Corticosteroids

Use of Corticosteroids With PD-1 or PD-L1 Inhibitors Associated With Poorer Outcomes in NSCLC

Use of Corticosteroids With PD-1 or PD-L1 Inhibitors Associated With Poorer Outcomes in NSCLC

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A retrospective study of patients with NSCLC from 2 cancer centers demonstrates that concurrent use of corticosteroids with PD-1 or PD-L1 inhibitors at baseline decreases progression-free and overall survival for these patients.

Data on Corticosteroid-Related Adverse Events in Advanced Cancer Are Lacking, Needed

Data on Corticosteroid-Related Adverse Events in Advanced Cancer Are Lacking, Needed

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Although corticosteroids are frequently used to manage adverse effects (AEs), data on AEs related to these agents are lacking. Therefore, these researchers sought to determine if better reporting of corticosteroid-related AEs would be of benefit.

ITP Treatment Outcomes Not Improved With Intravenous vs Oral Corticosteroids

ITP Treatment Outcomes Not Improved With Intravenous vs Oral Corticosteroids

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In this prospective study, researchers sought to compare the effectiveness of IV methylprednisolone vs oral prednisone in hospitalized patients with newly diagnosed ITP.

High-Dose Dexamethasone Effective With Less Adverse Effects in ITP vs Corticosteroids

High-Dose Dexamethasone Effective With Less Adverse Effects in ITP vs Corticosteroids

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In this randomized trial, investigators sought to determine the effectiveness of high-dose dexamethasone vs conventional prednisone therapy in treatment-naïve patients with ITP. Results were presented at ASH 2017.

Pomalidomide extends survival in multiple myeloma

A new immunomodulatory drug under FDA review significantly increased survival in persons with multiple myeloma, including older patients.

Steroid-induced osteoporotic fracture

Reviews steroid-induced ostoporotic fracture and its management

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