Colorectal Cancer

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

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Researchers conducted a case-control study to determine whether colonoscopy is associated with decreased CRC mortality in veterans and whether its effect differs by anatomical location of CRC.

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

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A prospective study assessing the outcomes of a cohort of participants in the CALGB 89803 study determined the effect of following the American Cancer Society guidelines on survival for persons with colon cancer.

Modified XELIRI Noninferior to FOLFIRI for OS in Metastatic Colorectal Cancer

Modified XELIRI Noninferior to FOLFIRI for OS in Metastatic Colorectal Cancer

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Results of the phase 3 AXEPT study were used to determine the noninferiority of a modified XELIRI regimen vs a FOLFIRI regimen in terms of overall survival among patients with metastatic colorectal cancer (mCRC).

Colorectal Cancer Screening Rate Increased by Digital Self-Ordering

Colorectal Cancer Screening Rate Increased by Digital Self-Ordering

Fifty-three percent of intervention participants used app to self-order a colorectal screening test.

Increased Nut Consumption May Reduce Colon Cancer Recurrence, Death

Increased Nut Consumption May Reduce Colon Cancer Recurrence, Death

Investigators conducted a prospective observational study involving patients with stage III colon cancer to examine the correlation of nut intake with cancer mortality.

Recognizing Reduced Dietary Intake in Hospitalized Patients With Colorectal Cancer

Recognizing Reduced Dietary Intake in Hospitalized Patients With Colorectal Cancer

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Analysis revealed factors that contribute to reduced dietary intake among hospitalized patients with colorectal cancer.

Proinflammatory Diet Associated With Increased Colorectal Cancer Risk

Proinflammatory Diet Associated With Increased Colorectal Cancer Risk

Investigators examined correlations between an empirical dietary inflammatory pattern (EDIP) score and colorectal cancer risk.

Partial Response Achieved With Atezolizumab, Cobimetinib in Pretreated CRC

Partial Response Achieved With Atezolizumab, Cobimetinib in Pretreated CRC

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Safety and efficacy of atezolizumab with cobimetinib for heavily pretreated metastatic CRC was demonstrated in a phase 1b study that was presented at the 2018 Gastrointestinal Cancers Symposium.

Novel Approach Can Improve Both Colorectal Cancer Screening Outcomes and Adherence

Novel Approach Can Improve Both Colorectal Cancer Screening Outcomes and Adherence

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Study results presented at the 2018 Gastrointestinal Cancers Symposium demonstrated the sensitivity and specificity of the CMx biomimetic platform, a novel approach to detecting CRC and precancerous lesions that could improve screening rates.

Aromatase Inhibitor Use Does Not Increase Risk of Colorectal Cancer

Aromatase Inhibitor Use Does Not Increase Risk of Colorectal Cancer

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No additional risk of colorectal cancer was noted among women treated with aromatase inhibitors (AIs) following a median follow-up of 2.4 and 2.9 years.

Colorectal Cancer and Dietary Fiber: Source Is More Important Than Amount

Colorectal Cancer and Dietary Fiber: Source Is More Important Than Amount

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New research on the benefits of high-fiber diets for CRC survivors took its findings one step further and identified the type of fiber consumed and which provided better benefits.

Fiber Associated With Reduced Mortality in Those With Colorectal Cancer

Fiber Associated With Reduced Mortality in Those With Colorectal Cancer

Increasing fiber consumption after diagnosis may lower risk of all-cause, CRC-specific mortality.

Aprepitant Plus Standard Antiemetic Regimen Prevents CINV With FOLFOX for CRC

Aprepitant Plus Standard Antiemetic Regimen Prevents CINV With FOLFOX for CRC

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A small study of 50 patients undergoing FOLFOX for CRC determined if adding aprepitant to standard antiemetic prophylactic treatment would improve CINV in this patient population.

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

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An analysis of 23 studies focused on interventions with the potential to improve follow-up colonoscopy completion rates found that navigation programs are more effective than other interventions studied.

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

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Investigators sought to determine clinical and cost effectiveness of additional colonoscopy screening in patients undergoing FIT screening for colorectal cancer.

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

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Bevacizumab-awwb is a recombinant IgG1 monoclonal antibody that works by binding to vascular endothelial growth factor (VEGF) and inhibits angiogenesis.

Sarcopenia Affects Dose in Reinduction Therapy for Metastatic Colorectal Cancer

Sarcopenia Affects Dose in Reinduction Therapy for Metastatic Colorectal Cancer

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Sarcopenia is significantly associated with dose reductions but not with dose-limiting toxicities at initiation of CAPOX-B reinduction therapy in patients with mCRC, researchers reported at ESMO 2017 Congress.

Educational Program Explains Biomarker Testing for Colorectal Cancer

Educational Program Explains Biomarker Testing for Colorectal Cancer

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A newly developed patient education resource helps nurses educate patients with colorectal cancer about biomarker testing and counsel them on the significance of the results.

Colorectal Cancer Recurrence Lower in Survivors Who Exercise

Colorectal Cancer Recurrence Lower in Survivors Who Exercise

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Researchers examined the impact of exercise and low body fat mass on recurrence of colorectal polyps among survivors of colorectal cancer.

Colorectal Cancer Mortality Rates Down in African Americans

Colorectal Cancer Mortality Rates Down in African Americans

Among adults aged 20 to 54 years, increase in CRC mortality only seen in whites aged 30 to 54 years.

Financial Incentive Motivates Colorectal Cancer Screening

Financial Incentive Motivates Colorectal Cancer Screening

Researchers investigated whether a financial reward could help drive colorectal cancer participation.

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

This research aims to assess the correlation between quality of life (QoL) and severity of dermatological toxicity in patients with metastatic colorectal cancer.

MSTF Releases Updated Recommendations for Colorectal Cancer Screening

MSTF Releases Updated Recommendations for Colorectal Cancer Screening

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The United States Multi-Society Task Force (MSTF) on Colorectal Cancer Screening updated its recommendations, confirming that screening in people at average risk should begin at age 50 years. The update also includes a ranking of current screening modalities.

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

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Regular use of NSAIDs after diagnosis of colorectal cancer correlated with improved survival in survivors with KRAS wild-type tumors.

Doxorubicin Efficacy Improved, Cardiotoxicity Reduced With Adjuvant Fidarest for Colon Cancer

Doxorubicin Efficacy Improved, Cardiotoxicity Reduced With Adjuvant Fidarest for Colon Cancer

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The AR inhibitor fidarestat is effective as adjuvant therapy to enhance doxorubicin sensitivity of colorectal cancer cells and to reduce cardiotoxicity associated with the drug.

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

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By identifying incidence, prevalence, and risk factors for colorectal and pancreatic cancer in our communities, nurse navigators can develop screening and prevention programs to better serve these populations.

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

[Cancer Management and Research] This research examines preferences and risk tolerance among patients and oncologists in the USA for anticancer drugs to treat metastatic colorectal cancer (mCRC).

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

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Study compared FOLFOXIRI/bevacizumab and FOLFOX/bevacizumab in patients with metastatic colorectal cancer.

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

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'Conquer Fear' decreased fear among survivors of breast and colorectal cancer and melanoma compared with relaxation techniques.

Tumor Mutation Load Higher in Younger Patients With Colon Cancer

Tumor Mutation Load Higher in Younger Patients With Colon Cancer

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Tumor mutation load (TML) may be a factor in higher rates of colorectal cancer among younger persons as TML is 3 times higher in younger patients with colorectal cancer.

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