Colorectal Cancer

Surgical Practices May Explain International Survival Differences in Cancer Treatment

Surgical Practices May Explain International Survival Differences in Cancer Treatment

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Overall, patient survival was not associated with surgical technique.

Risk of Advanced Colorectal Neoplasia Higher Among Some Survivors of Hodgkin Lymphoma

Risk of Advanced Colorectal Neoplasia Higher Among Some Survivors of Hodgkin Lymphoma

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Researchers present results of an interim analysis of a study on the prevalence of advanced colorectal neoplasia among survivors of Hodgkin lymphoma.

Curative Option Identified for Squamous Cell Carcinoma of the Anal Canal With Distant Metastasis

Curative Option Identified for Squamous Cell Carcinoma of the Anal Canal With Distant Metastasis

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A retrospective review identified a subset of patients with squamous cell carcinoma of the anal canal with distant metastases who respond to extended-field chemoradiation.

Dietary Habits May Prolong Survival in Patients With Colorectal Cancer

Dietary Habits May Prolong Survival in Patients With Colorectal Cancer

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A prospective analysis of diets before and after diagnosis revealed dietary habits among patients with colorectal cancer that may help prolong survival.

SCOOPs Program Improves Patient Experience, Reduces Costs

SCOOPs Program Improves Patient Experience, Reduces Costs

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Researchers report on the effectiveness results of the Supportive Care of Oncology Patients (SCOOPs) Program were presented at the 2018 ASCO Quality Care Symposium.

Estimating Quality of Life Based on Cumulative Drug Toxicity in Colorectal Cancer

Estimating Quality of Life Based on Cumulative Drug Toxicity in Colorectal Cancer

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Results of a study in which more than 100 patients with metastatic colorectal cancer completed EORTC-QLQ-C30 suggests an association between assessment of cumulative drug toxicities and predictions of quality of life for patients undergoing first-line chemotherapy for the disease.

CDC Reports Screening Drop in Breast, Cervical, and Prostate Cancers

CDC Reports Screening Drop in Breast, Cervical, and Prostate Cancers

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CDC investigators found that from 2000 to 2015, screening for breast, cervical, and prostate cancers decreased significantly.

Bariatric Surgery Reduced Risk of Some Cancers in Obese Patients

Bariatric Surgery Reduced Risk of Some Cancers in Obese Patients

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Weight loss associated with bariatric surgery could reduce risk of hormone-related cancers, but an increased risk for colorectal cancer was seen in patients who underwent gastric bypass.

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

A retrospective review of data from the National Cancer Data Base demonstrated that trends in rectal cancer may follow a pattern similar to that of colon cancer.

Novel Quinazoline-based Sulfonamide Derivative (3D) Induces Apoptosis in Colorectal Cancer by Inhibiting JAK2-STAT3 Pathway

Novel Quinazoline-based Sulfonamide Derivative (3D) Induces Apoptosis in Colorectal Cancer by Inhibiting JAK2-STAT3 Pathway

[OncoTargets and Therapy] Researchers investigated the anticancer effects of a novel sulfonamide derivative in the treatment of colorectal cancer.

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

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Study results presented at 2018 ASCO Annual Meeting demonstrated effectiveness of ado-trastuzumab emtansine in non-breast non-gastric HER2-amplified cancers.

Emerging Treatment Options for BRAF-mutant Colorectal Cancer

Emerging Treatment Options for BRAF-mutant Colorectal Cancer

[Gastrointestinal Cancer: Targets and Therapy] This review presents the most up-to-date molecular, clinical, and therapeutic data, including an overview of a current phase 3 study assessing the efficacy of simultaneous BRAF, EGFR, and MEK inhibition among patients with BRAFV600E-mutant CRC.

Insurance Type Influences Colon Cancer Survival

Insurance Type Influences Colon Cancer Survival

Researchers evaluated survival in patients with colon cancer, according to the type of insurance the patients held.

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

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A review of the literature on follow-up after positive screening results led researchers to a consensus opinion on timing of diagnostic tests for 4 cancers: breast, cervical, colorectal, and lung.

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

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A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

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Researchers conducted a case-control study to determine whether colonoscopy is associated with decreased CRC mortality in veterans and whether its effect differs by anatomical location of CRC.

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

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A prospective study assessing the outcomes of a cohort of participants in the CALGB 89803 study determined the effect of following the American Cancer Society guidelines on survival for persons with colon cancer.

Modified XELIRI Noninferior to FOLFIRI for OS in Metastatic Colorectal Cancer

Modified XELIRI Noninferior to FOLFIRI for OS in Metastatic Colorectal Cancer

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Results of the phase 3 AXEPT study were used to determine the noninferiority of a modified XELIRI regimen vs a FOLFIRI regimen in terms of overall survival among patients with metastatic colorectal cancer (mCRC).

Colorectal Cancer Screening Rate Increased by Digital Self-Ordering

Colorectal Cancer Screening Rate Increased by Digital Self-Ordering

Fifty-three percent of intervention participants used app to self-order a colorectal screening test.

Increased Nut Consumption May Reduce Colon Cancer Recurrence, Death

Increased Nut Consumption May Reduce Colon Cancer Recurrence, Death

Investigators conducted a prospective observational study involving patients with stage III colon cancer to examine the correlation of nut intake with cancer mortality.

Recognizing Reduced Dietary Intake in Hospitalized Patients With Colorectal Cancer

Recognizing Reduced Dietary Intake in Hospitalized Patients With Colorectal Cancer

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Analysis revealed factors that contribute to reduced dietary intake among hospitalized patients with colorectal cancer.

Proinflammatory Diet Associated With Increased Colorectal Cancer Risk

Proinflammatory Diet Associated With Increased Colorectal Cancer Risk

Investigators examined correlations between an empirical dietary inflammatory pattern (EDIP) score and colorectal cancer risk.

Partial Response Achieved With Atezolizumab, Cobimetinib in Pretreated CRC

Partial Response Achieved With Atezolizumab, Cobimetinib in Pretreated CRC

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Safety and efficacy of atezolizumab with cobimetinib for heavily pretreated metastatic CRC was demonstrated in a phase 1b study that was presented at the 2018 Gastrointestinal Cancers Symposium.

Novel Approach Can Improve Both Colorectal Cancer Screening Outcomes and Adherence

Novel Approach Can Improve Both Colorectal Cancer Screening Outcomes and Adherence

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Study results presented at the 2018 Gastrointestinal Cancers Symposium demonstrated the sensitivity and specificity of the CMx biomimetic platform, a novel approach to detecting CRC and precancerous lesions that could improve screening rates.

Aromatase Inhibitor Use Does Not Increase Risk of Colorectal Cancer

Aromatase Inhibitor Use Does Not Increase Risk of Colorectal Cancer

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No additional risk of colorectal cancer was noted among women treated with aromatase inhibitors (AIs) following a median follow-up of 2.4 and 2.9 years.

Colorectal Cancer and Dietary Fiber: Source Is More Important Than Amount

Colorectal Cancer and Dietary Fiber: Source Is More Important Than Amount

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New research on the benefits of high-fiber diets for CRC survivors took its findings one step further and identified the type of fiber consumed and which provided better benefits.

Fiber Associated With Reduced Mortality in Those With Colorectal Cancer

Fiber Associated With Reduced Mortality in Those With Colorectal Cancer

Increasing fiber consumption after diagnosis may lower risk of all-cause, CRC-specific mortality.

Aprepitant Plus Standard Antiemetic Regimen Prevents CINV With FOLFOX for CRC

Aprepitant Plus Standard Antiemetic Regimen Prevents CINV With FOLFOX for CRC

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A small study of 50 patients undergoing FOLFOX for CRC determined if adding aprepitant to standard antiemetic prophylactic treatment would improve CINV in this patient population.

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

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An analysis of 23 studies focused on interventions with the potential to improve follow-up colonoscopy completion rates found that navigation programs are more effective than other interventions studied.

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

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Investigators sought to determine clinical and cost effectiveness of additional colonoscopy screening in patients undergoing FIT screening for colorectal cancer.

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