Surgical Practices May Explain International Survival Differences in Cancer Treatment

Surgical Practices May Explain International Survival Differences in Cancer Treatment

Overall, patient survival was not associated with surgical technique.

Risk of Advanced Colorectal Neoplasia Higher Among Some Survivors of Hodgkin Lymphoma

Risk of Advanced Colorectal Neoplasia Higher Among Some Survivors of Hodgkin Lymphoma

Researchers present results of an interim analysis of a study on the prevalence of advanced colorectal neoplasia among survivors of Hodgkin lymphoma.

Curative Option Identified for Squamous Cell Carcinoma of the Anal Canal With Distant Metastasis

Curative Option Identified for Squamous Cell Carcinoma of the Anal Canal With Distant Metastasis

A retrospective review identified a subset of patients with squamous cell carcinoma of the anal canal with distant metastases who respond to extended-field chemoradiation.

Risk for Colon Cancer, Osteogenic Sarcoma Higher With Presence of Diamond-Blackfan Anemia

Risk for Colon Cancer, Osteogenic Sarcoma Higher With Presence of Diamond-Blackfan Anemia

Researchers reviewed cancer incidence in patients with Diamond-Blackfan anemia.

Dietary Habits May Prolong Survival in Patients With Colorectal Cancer

Dietary Habits May Prolong Survival in Patients With Colorectal Cancer

A prospective analysis of diets before and after diagnosis revealed dietary habits among patients with colorectal cancer that may help prolong survival.

SCOOPs Program Improves Patient Experience, Reduces Costs

SCOOPs Program Improves Patient Experience, Reduces Costs

Researchers report on the effectiveness results of the Supportive Care of Oncology Patients (SCOOPs) Program were presented at the 2018 ASCO Quality Care Symposium.

Estimating Quality of Life Based on Cumulative Drug Toxicity in Colorectal Cancer

Estimating Quality of Life Based on Cumulative Drug Toxicity in Colorectal Cancer

Results of a study in which more than 100 patients with metastatic colorectal cancer completed EORTC-QLQ-C30 suggests an association between assessment of cumulative drug toxicities and predictions of quality of life for patients undergoing first-line chemotherapy for the disease.

Computer-Aided Colonoscopy Reliably Identifies Small Polyps

Computer-Aided Colonoscopy Reliably Identifies Small Polyps

Researchers evaluated the performance of real-time CAD with endocytoscopes among 791 consecutive patients undergoing colonoscopy.

CDC Reports Screening Drop in Breast, Cervical, and Prostate Cancers

CDC Reports Screening Drop in Breast, Cervical, and Prostate Cancers

CDC investigators found that from 2000 to 2015, screening for breast, cervical, and prostate cancers decreased significantly.

Bariatric Surgery Reduced Risk of Some Cancers in Obese Patients

Bariatric Surgery Reduced Risk of Some Cancers in Obese Patients

Weight loss associated with bariatric surgery could reduce risk of hormone-related cancers, but an increased risk for colorectal cancer was seen in patients who underwent gastric bypass.

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

A retrospective review of data from the National Cancer Data Base demonstrated that trends in rectal cancer may follow a pattern similar to that of colon cancer.

Novel Quinazoline-based Sulfonamide Derivative (3D) Induces Apoptosis in Colorectal Cancer by Inhibiting JAK2-STAT3 Pathway

Novel Quinazoline-based Sulfonamide Derivative (3D) Induces Apoptosis in Colorectal Cancer by Inhibiting JAK2-STAT3 Pathway

[OncoTargets and Therapy] Researchers investigated the anticancer effects of a novel sulfonamide derivative in the treatment of colorectal cancer.

FDA-Approved Colorectal Cancer Drug Treatments

Colorectal cancer treatment regimen chart.

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

Ado-trastuzumab Emtansine Effective in HER2 Amplified Non-breast, Non-gastric Cancers

Study results presented at 2018 ASCO Annual Meeting demonstrated effectiveness of ado-trastuzumab emtansine in non-breast non-gastric HER2-amplified cancers.

Emerging Treatment Options for BRAF-mutant Colorectal Cancer

Emerging Treatment Options for BRAF-mutant Colorectal Cancer

[Gastrointestinal Cancer: Targets and Therapy] This review presents the most up-to-date molecular, clinical, and therapeutic data, including an overview of a current phase 3 study assessing the efficacy of simultaneous BRAF, EGFR, and MEK inhibition among patients with BRAFV600E-mutant CRC.

Insurance Type Influences Colon Cancer Survival

Insurance Type Influences Colon Cancer Survival

Researchers evaluated survival in patients with colon cancer, according to the type of insurance the patients held.

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

Cancer Screening Follow-up: Enabling Timely Diagnosis, Treatment

A review of the literature on follow-up after positive screening results led researchers to a consensus opinion on timing of diagnostic tests for 4 cancers: breast, cervical, colorectal, and lung.

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

Hope, Optimism Reduce Psychological Distress in Advanced Cancer

A cross-sectional analysis evaluated the impact of hope and optimism on different facets of psychological distress among patients with advanced melanoma, colorectal, lung, or gastrointestinal cancers.

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Researchers conducted a case-control study to determine whether colonoscopy is associated with decreased CRC mortality in veterans and whether its effect differs by anatomical location of CRC.

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

A prospective study assessing the outcomes of a cohort of participants in the CALGB 89803 study determined the effect of following the American Cancer Society guidelines on survival for persons with colon cancer.

Modified XELIRI Noninferior to FOLFIRI for OS in Metastatic Colorectal Cancer

Modified XELIRI Noninferior to FOLFIRI for OS in Metastatic Colorectal Cancer

Results of the phase 3 AXEPT study were used to determine the noninferiority of a modified XELIRI regimen vs a FOLFIRI regimen in terms of overall survival among patients with metastatic colorectal cancer (mCRC).

Colorectal Cancer Screening Rate Increased by Digital Self-Ordering

Colorectal Cancer Screening Rate Increased by Digital Self-Ordering

Fifty-three percent of intervention participants used app to self-order a colorectal screening test.

Increased Nut Consumption May Reduce Colon Cancer Recurrence, Death

Increased Nut Consumption May Reduce Colon Cancer Recurrence, Death

Investigators conducted a prospective observational study involving patients with stage III colon cancer to examine the correlation of nut intake with cancer mortality.

Evidence-Based Approach Improves Rate of Colon Surgical Site Infections

Evidence-Based Approach Improves Rate of Colon Surgical Site Infections

Study results presented at the NACNS 2018 Annual Conference demonstrate the efficacy of SSI bundle element compliance and multidisciplinary clinical collaboration in reducing colon surgical site infections.

Recognizing Reduced Dietary Intake in Hospitalized Patients With Colorectal Cancer

Recognizing Reduced Dietary Intake in Hospitalized Patients With Colorectal Cancer

Analysis revealed factors that contribute to reduced dietary intake among hospitalized patients with colorectal cancer.

Proinflammatory Diet Associated With Increased Colorectal Cancer Risk

Proinflammatory Diet Associated With Increased Colorectal Cancer Risk

Investigators examined correlations between an empirical dietary inflammatory pattern (EDIP) score and colorectal cancer risk.

Partial Response Achieved With Atezolizumab, Cobimetinib in Pretreated CRC

Partial Response Achieved With Atezolizumab, Cobimetinib in Pretreated CRC

Safety and efficacy of atezolizumab with cobimetinib for heavily pretreated metastatic CRC was demonstrated in a phase 1b study that was presented at the 2018 Gastrointestinal Cancers Symposium.

Novel Approach Can Improve Both Colorectal Cancer Screening Outcomes and Adherence

Novel Approach Can Improve Both Colorectal Cancer Screening Outcomes and Adherence

Study results presented at the 2018 Gastrointestinal Cancers Symposium demonstrated the sensitivity and specificity of the CMx biomimetic platform, a novel approach to detecting CRC and precancerous lesions that could improve screening rates.

Aromatase Inhibitor Use Does Not Increase Risk of Colorectal Cancer

Aromatase Inhibitor Use Does Not Increase Risk of Colorectal Cancer

No additional risk of colorectal cancer was noted among women treated with aromatase inhibitors (AIs) following a median follow-up of 2.4 and 2.9 years.

Colorectal Cancer and Dietary Fiber: Source Is More Important Than Amount

Colorectal Cancer and Dietary Fiber: Source Is More Important Than Amount

New research on the benefits of high-fiber diets for CRC survivors took its findings one step further and identified the type of fiber consumed and which provided better benefits.

Fiber Associated With Reduced Mortality in Those With Colorectal Cancer

Fiber Associated With Reduced Mortality in Those With Colorectal Cancer

Increasing fiber consumption after diagnosis may lower risk of all-cause, CRC-specific mortality.

Aprepitant Plus Standard Antiemetic Regimen Prevents CINV With FOLFOX for CRC

Aprepitant Plus Standard Antiemetic Regimen Prevents CINV With FOLFOX for CRC

A small study of 50 patients undergoing FOLFOX for CRC determined if adding aprepitant to standard antiemetic prophylactic treatment would improve CINV in this patient population.

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

An analysis of 23 studies focused on interventions with the potential to improve follow-up colonoscopy completion rates found that navigation programs are more effective than other interventions studied.

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

Investigators sought to determine clinical and cost effectiveness of additional colonoscopy screening in patients undergoing FIT screening for colorectal cancer.

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

Bevacizumab-awwb is a recombinant IgG1 monoclonal antibody that works by binding to vascular endothelial growth factor (VEGF) and inhibits angiogenesis.

Sarcopenia Affects Dose in Reinduction Therapy for Metastatic Colorectal Cancer

Sarcopenia Affects Dose in Reinduction Therapy for Metastatic Colorectal Cancer

Sarcopenia is significantly associated with dose reductions but not with dose-limiting toxicities at initiation of CAPOX-B reinduction therapy in patients with mCRC, researchers reported at ESMO 2017 Congress.

Educational Program Explains Biomarker Testing for Colorectal Cancer

Educational Program Explains Biomarker Testing for Colorectal Cancer

A newly developed patient education resource helps nurses educate patients with colorectal cancer about biomarker testing and counsel them on the significance of the results.

Colorectal Cancer Recurrence Lower in Survivors Who Exercise

Colorectal Cancer Recurrence Lower in Survivors Who Exercise

Researchers examined the impact of exercise and low body fat mass on recurrence of colorectal polyps among survivors of colorectal cancer.

Colorectal Cancer Mortality Rates Down in African Americans

Colorectal Cancer Mortality Rates Down in African Americans

Among adults aged 20 to 54 years, increase in CRC mortality only seen in whites aged 30 to 54 years.

Colorectal Cancer Recurrence Lower in Survivors Who Exercise, Have Low Body Fat Mass

Colorectal Cancer Recurrence Lower in Survivors Who Exercise, Have Low Body Fat Mass

This study investigated the impact of exercise (1 hour/week) and low body fat mass on recurrence of colorectal polyp recurrence among survivors of colorectal cancer.

Financial Incentive Motivates Colorectal Cancer Screening

Financial Incentive Motivates Colorectal Cancer Screening

Researchers investigated whether a financial reward could help drive colorectal cancer participation.

Obesity in Adolescents Ups Colon and Rectal Cancer Risk in Adulthood

Obesity in Adolescents Ups Colon and Rectal Cancer Risk in Adulthood

Overweight teens in Israel had about a 53 percent higher risk for colon cancer as adults, researchers found.

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

This research aims to assess the correlation between quality of life (QoL) and severity of dermatological toxicity in patients with metastatic colorectal cancer.

MSTF Releases Updated Recommendations for Colorectal Cancer Screening

MSTF Releases Updated Recommendations for Colorectal Cancer Screening

The United States Multi-Society Task Force (MSTF) on Colorectal Cancer Screening updated its recommendations, confirming that screening in people at average risk should begin at age 50 years. The update also includes a ranking of current screening modalities.

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

Regular use of NSAIDs after diagnosis of colorectal cancer correlated with improved survival in survivors with KRAS wild-type tumors.

Doxorubicin Efficacy Improved, Cardiotoxicity Reduced With Adjuvant Fidarest for Colon Cancer

Doxorubicin Efficacy Improved, Cardiotoxicity Reduced With Adjuvant Fidarest for Colon Cancer

The AR inhibitor fidarestat is effective as adjuvant therapy to enhance doxorubicin sensitivity of colorectal cancer cells and to reduce cardiotoxicity associated with the drug.

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

By identifying incidence, prevalence, and risk factors for colorectal and pancreatic cancer in our communities, nurse navigators can develop screening and prevention programs to better serve these populations.

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

[Cancer Management and Research] This research examines preferences and risk tolerance among patients and oncologists in the USA for anticancer drugs to treat metastatic colorectal cancer (mCRC).

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

Study compared FOLFOXIRI/bevacizumab and FOLFOX/bevacizumab in patients with metastatic colorectal cancer.

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

'Conquer Fear' decreased fear among survivors of breast and colorectal cancer and melanoma compared with relaxation techniques.

ACS Survivorship Guidelines for Healthy Behaviors Beneficial for Colon Cancer Survivors

ACS Survivorship Guidelines for Healthy Behaviors Beneficial for Colon Cancer Survivors

Patients with stage III colon cancer who follow the ACS guidelines for a healthy lifestyle after adjuvant chemotherapy had longer disease-free survival and overall survival.

Consuming Tree Nuts Improves DFS, OS in Survivors of Colon Cancer

Consuming Tree Nuts Improves DFS, OS in Survivors of Colon Cancer

Consumption of tree nuts is associated with significantly improved disease-free survival (DFS) and overall survival (OS) in survivors of stage III colon cancer who consume 2 or more servings per week.

Tumor Mutation Load Higher in Younger Patients With Colon Cancer

Tumor Mutation Load Higher in Younger Patients With Colon Cancer

Tumor mutation load (TML) may be a factor in higher rates of colorectal cancer among younger persons as TML is 3 times higher in younger patients with colorectal cancer.

Comprehensive After Surgery Recovery Program Reduces Complication Rates and Improves Surgical Outcomes

Comprehensive After Surgery Recovery Program Reduces Complication Rates and Improves Surgical Outcomes

Postoperative program improves complication rates, opioid prescribing, and hospital mortality and increases home discharge rates after colorectal or hip fracture surgery.

Prunes and Colon Cancer Prevention

Prunes and Colon Cancer Prevention

Scientists at Texas A&M University traced how eating a daily dose of prunes affects colon biochemistry, and the role this diet may play in cancer prevention.

Risk for Disease, Advanced Stage at Diagnosis Higher With Delayed Colonoscopy After Positive FIT Results

Risk for Disease, Advanced Stage at Diagnosis Higher With Delayed Colonoscopy After Positive FIT Results

Waiting 10 months or longer before follow-up colonoscopy after a positive FIT result is associated with higher risk of disease as well as advanced stage at diagnosis.

Prebiotic Qualities of Dried Plums Identified as a Colon Cancer Preventative

Prebiotic Qualities of Dried Plums Identified as a Colon Cancer Preventative

Consuming the equivalent of 5 prunes per day may provide a unique combination of biologically active compounds that can reduce the risk of colon cancer.

Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors

Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors

Including beans and whole grains such as rice in the diet is associated with a reduced burden of CRC in survivors.

Self-efficacy Level Predictive of Likelihood to Follow Through With Colorectal Cancer Screening

Self-efficacy Level Predictive of Likelihood to Follow Through With Colorectal Cancer Screening

Patients' confidence with colorectal cancer screening procedures is predictive of their likelihood to schedule and follow through with screening.

Survival Better for Hispanics, Blacks With Colorectal Cancer but HR-QoL Is Better for Whites

Survival Better for Hispanics, Blacks With Colorectal Cancer but HR-QoL Is Better for Whites

Although median survival is longer for Hispanic and black patients compared with white patients, health-related QoL is poor for minority patients.

Rates of Colorectal Cancer Screening Lower for Adults With Disabilities

Rates of Colorectal Cancer Screening Lower for Adults With Disabilities

Transportation issues, lack of awareness, other barriers may be to blame for diminished colorectal screening rates.

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

Predictive risk model shows that lifestyle choices have a greater influence on risk for colorectal cancer than does genetic factors.

Colorectal Cancer Rates Increased Sharply Among Generation X and Millennials

Colorectal Cancer Rates Increased Sharply Among Generation X and Millennials

Incidence of colon and rectal cancers are increasing sharply in people younger than 50 years, the recommended age for initiating screening.

Colorectal Cancer in 2017: Incidence Rates Going Up in Younger Patients, Down in Older Patients

Colorectal Cancer in 2017: Incidence Rates Going Up in Younger Patients, Down in Older Patients

ACS colorectal cancer statistics show an overall decrease in incidence due to increases in screening rates; however, age-related incidence is trending up in younger persons, down in older persons.

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

Outcomes improved with short-course radiation and delay to surgery of 4 to 8 weeks.

Colorectal Cancer Risk Higher With Poor Metabolic Health vs Increased Weight

Colorectal Cancer Risk Higher With Poor Metabolic Health vs Increased Weight

Women with poor metabolic health have a greater risk of colorectal cancer than those with increased weight.

Chemo May Be Overused Among Young, Middle-aged Adults With Colon Cancer

Chemo May Be Overused Among Young, Middle-aged Adults With Colon Cancer

Chemotherapy may be overused among young and middle-aged adults with colon cancer, with the addition of adjuvant chemotherapy not resulting in a matched survival benefit.

Geographic Location Affects Stage at Diagnosis of Colon Cancer in Segregated Communities

Geographic Location Affects Stage at Diagnosis of Colon Cancer in Segregated Communities

Geographic location was seen to affect disease stage at diagnosis among people with colorectal cancer who live in ethnically or racially segregated communities.

The Affordable Care Act Has Increased the Use of Mammography But Not Colonoscopy

The Affordable Care Act Has Increased the Use of Mammography But Not Colonoscopy

An assessment of the use of mammography and colonoscopy among fee-for-service Medicare beneficiaries before and after the Affordable Care Act demonstrates the impact of out-of-pocket costs in this population.

ASCO: Moderate Activity Linked to Longer Survival in Advanced CRC

ASCO: Moderate Activity Linked to Longer Survival in Advanced CRC

Moderate but not vigorous activity proved beneficial for patients with metastatic colorectal cancer.

MABp1 Improves Symptoms vs Placebo in Colorectal Cancer

MABp1 Improves Symptoms vs Placebo in Colorectal Cancer

MABp1 (Xilonix) is an interleukin 1α-targeting antibody associated with antitumor activity and relief of debilitating symptoms in patients with advanced colorectal cancer. In this ongoing phase 3 clinical trial, its impact on other debilitating symptoms in this population was evaluated.

Omega-3 Polyunsaturated Fatty Acids in the Prevention of Postoperative Complications in Colorectal Cancer: A Meta-analysis

Omega-3 Polyunsaturated Fatty Acids in the Prevention of Postoperative Complications in Colorectal Cancer: A Meta-analysis

[OncoTargets and Therapy] This research evaluates the clinical efficacy of omega-3 PUFAs in the prevention of postoperative complications in colorectal cancer patients.

NSAIDs, Low-Dose Aspirin Best Options for Preventing Recurrent Adenomatous Colon Polyps

NSAIDs, Low-Dose Aspirin Best Options for Preventing Recurrent Adenomatous Colon Polyps

Researchers compared the effectiveness of NSAIDs, aspirin, and several nutritional supplements for the prevention of recurrent adenomatous neoplasia after colon polyp removal.

Drug-Drug Interaction Between Capecitabine and PPIs Reduces Survival in GI Cancers

Drug-Drug Interaction Between Capecitabine and PPIs Reduces Survival in GI Cancers

Drug-drug interaction between capecitabine and common heartburn medications has a negative effect on progression-free survival and overall survival in patients with GI cancer.

Multigene Panel Testing For Patients With Early-onset Colorectal Cancer

Multigene Panel Testing For Patients With Early-onset Colorectal Cancer

Given the frequency of gene mutations in patients with early-onset CRC, genetic counseling and testing could be considered for this population.

Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer

Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer

Study results demonstrate effectiveness of 4 weeks of prehabilitation on the physical fitness of older patients undergoing surgery for colorectal cancer.

Study Helps to Clarify Navigator Role in Colonoscopy Screening

Study Helps to Clarify Navigator Role in Colonoscopy Screening

Survey data from patients receiving care at Boston Medical Center who were navigated for colonoscopy screening illustrates how patients value the services of oncology patient navigators.

Prediagnostic Wine Consumption May Improve Survival After CRC

Prediagnostic Wine Consumption May Improve Survival After CRC

A possible association between moderate to heavy alcohol consumption has been shown in previous studies. In this study, investigators examined the relationship between alcohol consumption and colorectal cancer survival remains unclear.

Side of Origin Affects Colon Cancer Survival

Side of Origin Affects Colon Cancer Survival

Researchers observed a significant disparity in colon cancer mortality related to origin location, independent of confounding variables.

Benefits of FIT As CRC Screening Method Examined

Benefits of FIT As CRC Screening Method Examined

FIT has several advantages over gFOBT, but practical concerns should be considered

Replacing Neoadjuvant CRT with Multiagent Chemo Not Recommended for Rectal Cancer

Replacing Neoadjuvant CRT with Multiagent Chemo Not Recommended for Rectal Cancer

In this study, the impact of advancements in surgical technique and systemic therapy for stage II and III rectal cancers was assessed via a comparison of outcomes after neoadjuvant chemoradiotherapy followed by definitive resection with those for neoadjuvant multiagent chemotherapy without radiation therapy.

Men With Genetic Risk of CRC May Lower Risk Via Healthy Lifestyle

Men With Genetic Risk of CRC May Lower Risk Via Healthy Lifestyle

Adopting healthy lifestyle can cut 25-year risk for the disease from 29 to 13 percent.

Novel Colonoscopy Prep Is Poised to Improve Screening Rates for Colon Cancer

Novel Colonoscopy Prep Is Poised to Improve Screening Rates for Colon Cancer

Novel preparation formulation is as effective and safe as current colon prep for colonoscopy. Plus, study participants gave the prep experience a high satisfaction rating.

Health Insurance Expansion Linked to Improved CRC Resection Rates

Health Insurance Expansion Linked to Improved CRC Resection Rates

The model for the Affordable Care Act, the 2006 Massachusetts health care reform, was associated with increased resection rates and a reduced risk for emergency resection in patients with colorectal cancer.

New CRC Screening Option Opens the Door for New Conversations

New CRC Screening Option Opens the Door for New Conversations

A new colorectal cancer (CRC) screening test that can be done in the privacy of patients' homes, at their convenience, and with no prep needed may help patients overcome their reticence.

Adding Bevacizumab to Adjuvant Capecitabine Not Effective for mCRC

The combination of adjuvant bevacizumab and capecitabine failed to improve disease-free survival compared with capecitabine alone in patients with mCRC who had undergone potentially curative surgery.

Rolapitant Improves CINV Prevention in Patients With GI Cancers

Rolapitant Improves CINV Prevention in Patients With GI Cancers

Adding rolapitant to a 5-HT3 receptor antagonist and dexamethasone significantly improved the prevention of CINV in patients with GI and CRC cancers receiving highly or moderately emetogenic chemotherapy.

Study Identifies Factors Associated With Poor Care Coordination

Study Identifies Factors Associated With Poor Care Coordination

Patients who have little to no understanding of the health system, multiple comorbid conditions, do not receive a written treatment plan, or do not have contact with a cancer care coordinator or specialist nurse have significantly poorer care coordination.

Increasing Dietary Omega-3 Intake After Colorectal Cancer Diagnosis Improves Survival

Increasing Dietary Omega-3 Intake After Colorectal Cancer Diagnosis Improves Survival

Lifestyle and dietary measures for preventing colorectal cancer are extensively studied; however, in this study, researchers looked at a dietary measure that improved survival for patients after diagnosis.

Recently Discovered microRNA Controls Response to Oxaliplatin in Colorectal Cancer

Danish researchers identified a microRNA shown to predict whether a patient with colorectal cancer would be resistant to oxaliplatin treatment, a discovery that holds promise of improving both current treatment options and development of future treatment strategies.

Poor Compliance to Adjuvant Chemo Linked to Poorer Survival in Rectal Cancer

Poor Compliance to Adjuvant Chemo Linked to Poorer Survival in Rectal Cancer

Poor compliance to NCCN guidelines for adjuvant chemotherapy appears to be associated with poorer overall survival.

Metformin Use May Improve Survival in Patients With CRC, Diabetes

Research indicates that metformin can confer improved survival for patients with colorectal cancer that also have diabetes.

Adjuvant Therapy Improves Survival in Stage II Colon Cancer, Study Confirms

A very large retrospective study of patients with stage II colon cancer found adjuvant therapy improves survival, regardless of treatment regimen, patient age, or high-risk pathologic risk features.

Immunotherapy Combination is Effective in Colorectal Cancer

Cbimetinib and atezolizumab was well tolerated and demonstrated encouraging clinical activity in microsatellite stable colorectal cancer (CRC).

Advanced Endoscopy Techniques May Be Safe Alternative to Surgery for Most Difficult-to-Remove or Large Polyps

Advanced Endoscopy Techniques May Be Safe Alternative to Surgery for Most Difficult-to-Remove or Large Polyps

Most patients with large or difficult-to-remove colorectal polyps have a lower incidence of cancer than previously thought; therefore, more advanced endoscopic techniques that spare the colon may be a better and safer alternative to a traditional operation in some cases.

Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence

Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence

Genetic biomarkers from tumor DNA circulating in the bloodstream could indicate the risk for recurrence of colorectal cancer and the efficacy of chemotherapy after surgery.

In Stage II Colon Cancer, Adjuvant Chemo is Associated With Improved OS

In Stage II Colon Cancer, Adjuvant Chemo is Associated With Improved OS

Adjuvant chemotherapy is associated with improved overall survival in patients with stage II colon cancer regardless of treatment regimen, patient age, or high-risk pathologic risk features.

Rare Mutations in Immune-Related Genes Linked to Multiple Simultaneous Colorectal Cancer Tumors

Genetic mutations affecting the immune system were identified in patients who develop more than one CRC tumor at the same time, and understanding how these cancers develop could improve therapy targeting.

Elderly Patients Often Not Up-to-Date on Screening for Colorectal Cancer

Screening for colorectal cancer (CRC) is not widely used by Americans age 75 years and older, even though some patients are healthy and may benefit.

More Older Patients With Comorbidities Are Receiving Therapy for mCRC

The proportion of older patients with comorbidities receiving treatment for metastatic colorectal cancer (mCRC) has increased over the last 2 decades despite the overall percentage of older adults being treated remaining low.

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