Oral Therapy for Urinary Tract Infections in Adults

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ORAL URINARY TRACT INFECTION TREATMENTS
Generic Brand Form Strength Adult Dose Duration
CEPHALOSPORINS
cefadroxil caps 500mg Uncomplicated UTI: 1−2g once daily or in 2 divided doses
Complicated UTI: 2g/day in 2 divided doses
 
tabs 1g
susp 250mg/5mL, 500mg/5mL
cefixime Suprax chew tabs 100mg, 150mg, 200mg 400mg once daily or 200mg every 12hrs  
tabs 400mg
susp 100mg/5mL, 200mg/5mL, 500mg/5mL
cefpodoxime granules for susp 50mg/5mL, 100mg/5mL 100mg every 12hrs 7 days
tabs 100mg, 200mg
cefuroxime Ceftin tabs 250mg, 500mg 250mg twice daily 7−10 days
cephalexin Keflex caps 250mg, 500mg, 750mg Uncomplicated cystitis: 500mg every 12hrs; max 4g/day 7−14 days
NITROFURANTOINS
nitrofurantoin Furadantin susp 25mg/5mL 50−100mg 4 times daily.
Suppressive therapy: 50−100mg once daily at bedtime may suffice
 
Macrobid caps 100mg 100mg every 12hrs 7 days
Macro-
dantin
caps 25mg, 50mg, 100mg 50−100mg 4 times daily.
Long-term use: 50−100mg once daily at bedtime
7 days
PENICILLINS
amoxicillin caps 250mg, 500mg 250mg every 8hrs
tabs 500mg, 875mg
susp 125mg/5mL, 250mg/5mL
amoxicillin + clavulanic acid Augmentin tabs 250mg+
 
125mg, 500mg+
 
125mg, 875mg+
 
125mg
500mg every 12hrs or 250mg every 8hrs
susp 125mg+
 
31.25mg/5mL, 200mg+
 
28.5mg/5mL, 250mg+
 
62.5mg/5mL, 400mg+
 
57mg/5mL
chew-
able
125mg+
 
31.25mg, 200mg+
 
28.5mg, 250mg+
 
62.5mg, 400mg+
 
57mg
QUINOLONES
ciprofloxacin Cipro tabs 250mg, 500mg Acute uncomplicated cystitis due to E. coli, S. saprophyticus in females: 250mg every 12hrs. 3 days
susp 250mg/5mL, 500mg/5mL
Other UTI: 250−500mg every 12hrs 7−14 days
Cipro XR ext‑rel tabs 500mg, 1g Uncomplicated UTI: 500mg once daily 3 days
Complicated UTI, acute uncomplicated pyelonephritis: 1000mg once daily 7−14 days
levofloxacin Levaquin soln 25mg/mL Uncomplicated UTI: 250mg once daily 3 days
tabs 250mg, 500mg, 750mg Complicated UTI, acute pyelonephritis: 250mg once daily or 750mg once daily 250mg dose: 10 days
750mg dose: 5 days
ofloxacin tabs 200mg, 300mg, 400mg Uncomplicated cystitis: 200mg every 12hrs 3 days (E. coli or K. pneu-
moniae
); 7 days (other)
Complicated: 200mg every 12hrs 10 days
SULFONAMIDES
sulfameth-
oxazole + trimethoprim
susp 200mg+
 
40mg/5mL
20mL every 12hrs 10−14 days
Bactrim tabs 400mg+80mg 2 tabs every 12hrs
Septra
Bactrim DS tabs 800mg+
 
160mg
1 tab every 12hrs
Septra DS
OTHER CLASSES
fosfomycin Monurol granules for soln 3g Uncomplicated UTI: Females: Mix 1 sachet with 3−4oz of water (do not use hot water); drink immediately. Max 1 dose/episode. 1 dose
trimethoprim tabs 100mg, 200mg Uncomplicated UTI: 100mg twice daily, or 200mg once daily 10 days
Primsol soln 50mg/5mL
NOTES
Not an inclusive list of medications. Please see drug monographs at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 3/2018)

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