Bacterial Conjunctivitis Drug Treatments

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BACTERIAL CONJUNCTIVITIS TREATMENTS
Generic Brand Strength Size Form Dose
azithromycin Azasite Rx 1% 2.5mL soln¹ <1yr: Not recommended.
≥1yr: 1 drop twice daily (8−12hrs apart) for 2 days, then once daily for 5 days.
bacitracin Bacitracin Ophthalmic Ointment Rx 500U/g 3.5g oint Adults and Children: Apply 1−3 times daily.
Blepharitis: remove scales and crusts before applying to lid margins.
besifloxacin Besivance Rx 0.6% 5mL susp¹ <1yr: Not recommended.
≥1yr: 1 drop in affected eye(s) 3 times daily (4−12hrs apart) for 7 days. Shake bottle once before use.
ciprofloxacin Ciloxan Rx 0.3% 3.5g oint <2yrs: Not established.
≥2yrs: Apply ½ inch into conjunctival sac 3 times daily for 2 days, then twice daily for next 5 days.
5mL soln¹ Adults and Children: 1–2 drops in conjunctival sac(s) every 2hrs while awake for 2 days, then 1–2 drops every 4hrs while awake for next 5 days.
erythro-
mycin
Erythro-
mycin Ophthalmic Ointment
Rx 5mg/g 3.5g oint Adults and Children: Apply 1cm ribbon of ointment to infected area up to 6 times daily. Prophylaxis of neonatal gonoccocal or chlamydial conjunctivitis: instill 1cm ribbon of ointment into each lower conjunctival sac.
gatifloxacin Zymar Rx 0.3% 5mL soln¹ <1yr: Not established.
≥1yr: 1 drop every 2hrs while awake for 2 days (up to 8 times daily), then 1 drop 4 times daily while awake for 5 more days.
Zymaxid Rx 0.5% 2.5mL soln¹ <1yr: Not recommended.
≥1yr: 1 drop every 2hrs (max 8 doses) on Day 1 then 1 drop 2−4 times daily while awake on Days 2−7.
gentamicin
sulfate
Garamycin Rx 3mg/g 3.5g oint Adults and Children: Apply a ½ inch of ointment 2−3 times daily.
levofloxacin Quixin Rx 0.5% 1mL,
5mL
soln¹ <1yr: Not recommended.
≥1yr: 1−2 drops every 2hrs while awake (max 8 times/day) on Days 1 and 2, then 1−2 drops every 4hrs while awake (max 4 times/day) on Days 3−7.
moxifloxacin Moxeza Rx 0.5% 3mL soln <4mos: Not recommended.
≥4mos: 1 drop twice daily for 7 days.
Vigamox Rx 0.5% 3mL soln <1yr: Not recommended.
≥1yr: 1 drop 3 times daily for 7 days.
ofloxacin Ocuflox Rx 0.3% 5mL soln¹ <1yr: Not recommended.
≥1yr: 1−2 drops every 2−4hrs for 2 days, then 4 times daily for 5 more days.
polymyxin B sulfate Rx 10000U/g contact supplier oint Adults and Children: Apply every 3−4hrs for 7−10 days.
bacitracin zinc 500U/g
polymyxin B sulfate Rx 10000U/g contact supplier oint Adults and Children: Apply every 4hrs for 7−10 days.
bacitracin zinc 400U/g
neomycin (as sulfate) 3.5mg/g
polymyxin B sulfate Neosporin Rx 10000U/
 
mL
10mL soln³ Children: Not recommended.
Adults: 1−2 drops every 4hrs for 7−10 days. Max up to 2 drops every hour.
neomycin sulfate 1.75mg/
 
mL
gramicidin 0.025mg/
 
mL
polymyxin B sulfate Polytrim Rx 10000U/
 
mL
10mL soln¹ <2mos: Not recommended.
≥2mos: 1 drop every 3hrs for 7−10 days; max 6 doses/day.
trimetho-
prim 
sulfate
1mg/mL
sulfacet-
amide
sodium
Bleph‑10 Rx 10% 5mL soln¹ <2mos: Not recommended.
≥2mos: Initially 1−2 drops every 2−3hrs during the day (less often at night). Treat for 7−10 days.
tobramycin Tobrex Rx 0.3% 3.5g oint² Severe infections: Initially 2 drops every hour or ½ inch of ointment every 3−4hrs; then may prolong dosing interval. Mild to moderate infections: 1−2 drops every 4hrs or ½ inch of ointment 2−3 times daily.
5mL soln¹
NOTES

Do not wear contact lenses with signs and symptoms of bacterial conjunctivitis. To prevent contamination, the dropper tip should not touch the eyelids or surrounding areas. Keep the bottle tightly closed when not in use.
¹contains benzalkonium chloride. May be absorbed by soft contact lenses.
²contains chlorobutanol.
³contains alcohol, thimerosal.

Not an inclusive list of medications, official indications, and/or dosing. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 10/2017)

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