Chronic Myeloid Leukemia‎ News and Features

Conception, Pregnancy Possible During TKI Therapy for Chronic Myeloid Leukemia

Conception, Pregnancy Possible During TKI Therapy for Chronic Myeloid Leukemia

A retrospective and prospective study of Italian adult patients with CML investigated the potential for childbearing and outcomes in this patient population.

De-Escalation or Stoppage May Be Effective After Response to TKI Therapy in CML

De-Escalation or Stoppage May Be Effective After Response to TKI Therapy in CML

De-escalation of TKI therapy may be an effective management strategy among patients with CML who have responded to therapy.

Low-Dose Dasatinib for Chronic-Phase CML Safe, Effective With Fewer Adverse Events

Low-Dose Dasatinib for Chronic-Phase CML Safe, Effective With Fewer Adverse Events

In this study, researchers assigned 75 patients with newly diagnosed Philadelphia chromosome (Ph)-positive CML-CP to receive dasatinib 50 mg once daily.

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

Although many TKIs have well-documented cardiotoxic effects, results of a single-center prospective study that assessed effects of 1 year of therapy with imatinib or nilotinib in patients with CML demonstrated safety and efficacy of the 2 agents in this population.

Risk of Secondary Cancers With CML Linked to Disease, Not Treatment

Risk of Secondary Cancers With CML Linked to Disease, Not Treatment

This study examined the risk of secondary cancers among patients with CML who were treated with TKIs.

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