Antibiotics crucial after chemotherapy

Share this content:

Prophylactic antibiotics, barrier isolation, and air quality control measures can substantially reduce the risk of death in high-risk cancer patients after chemotherapy, a systematic review has shown. Researchers analysed 29 studies and found mortality risk was reduced 40 per cent at 30 days post-treatment when this combination of infection control measures was employed. However, inclusion of prophylactic antibiotics was crucial to show the beneficial effect on mortality. Analysis of a further 11 studies on inpatient versus outpatient management after haematopoietic stem-cell transplantation showed that all-cause mortality was 28 per cent lower in outpatients.

Schlesinger A, Paul M, Gafter-Gvili A et al. Lancet Infect Dis 2009;9(2):97-107

Originally published in the March 2009 edition of MIMS Oncology & Palliative Care.

You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs