Cancer In The Elderly

Mammograms may be beneficial for women over 75

Mammograms may be beneficial for women over 75

According to a study published in Radiology, women over 75, a population not typically included in mammography screening effectiveness studies, may benefit from mammograms.

Study Shows Older Patients With Breast Cancer Patients Do Follow Drug Therapy

Study Shows Older Patients With Breast Cancer Patients Do Follow Drug Therapy

Many older breast cancer patients with localized disease are taking drug treatments to prevent their cancer from returning, a new study finds. The research, covering a 7-year period, included more than 1,000 women, age 65 to 91 years, across the United States who had estrogen-positive breast cancer that had not spread.

New compound could reverse loss of muscle mass

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A new antibody could dramatically boost strength and muscle mass in patients with cancer, COPD, sporadic inclusion body myositis, and in elderly patients with sarcopenia.

U.S. Cancer Death Rates Decreasing

U.S. Cancer Death Rates Decreasing

The largest cancer death rate was decrease seen among black men aged 40 to 49 years; no drop for white women aged over 80 was observed.

Older people with Alzheimer's less likely to have cancer, and vice versa

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Although the occurrence of both cancer and Alzheimer's disease increases exponentially with age, researchers have discovered an inverse relationship between the two illnesses.

Pomalidomide extends survival in multiple myeloma

A new immunomodulatory drug under FDA review significantly increased survival in persons with multiple myeloma, including older patients.

Trastuzumab raises heart risk in older women with breast cancer

Heart failure is relatively common in older women undergoing breast cancer treatment, but trastuzumab therapy appears to raise the risk even more.

Withdrawn leukemia drug has good results in UK study

Gemtuzumab ozogamicin, discontinued here in 2010, reduced relapse risk and improved survival in Welsh patients with acute myeloid leukemia.

Radiotherapy after prostatectomy has long-term benefits

Administering radiotherapy after prostatectomy helped nearly two-thirds of users in a recent study remain free of prostate cancer after 10 years.

Older breast cancer patients have more complications with brachytherapy

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The breast cancer treatment brachytherapy, heralded for its low complication rates, actually results in more complications than whole-breast radiation 1 year after treatment.

All-cause mortality is reduced in elderly female cancer survivors who adhere to lifestyle guidelines

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Survival after cancer diagnosis in elderly female cancer survivors is improved by achieving and maintaining a healthy body weight, staying physically active, and maintaining a healthy diet.

HF/CM risks in breast chemotherapy

HF/CM risks in breast chemotherapy

Earlier study findings that anthracycline- or trastuzumab-based treatment for breast cancer raises the risk for heart failure and cardiomyopathy can be extended to a more general population of women.

Aspirin helps in some cancers

Aspirin helps in some cancers

Differences in the impact of aspirin in various forms of cancer are highlighted in two studies recently published in the oncology literature.

New colonoscopy schedule mirrors prior advice

Two of three main recommendations for colonoscopy surveillance are now supported by stronger evidence than they were in 2006.

Fit elderly patients with NSCLC should be considered for therapy

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Fit elderly patients with non-small cell lung cancer (NSCLC) should be considered for salvage targeted therapy. Many physicians use age to decide what therapy to give their patients, since validated biomarkers to direct treatment decisions are lacking.

Direct-mail FOBT kits bridge colorectal screening gap

The mailing of fecal occult blood test (FOBT) kits boosted colorectal cancer screening rates in a low-income, racially diverse patient population.

Disparities in surgical management of thyroid cancer

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ATA guidelines for well-differentiated thyroid cancer recommend therapeutic neck dissection when the disease is clinically involved or metastatic and prophylactic central neck dissection when tumors are advanced. Nonetheless, though these established guidelines are in place, the surgical management of cervical nodes varies greatly.

Radiation after lumpectomy might benefit older women after all

Most older women with early breast cancer are more likely to avoid mastectomy by following lumpectomy with radiation, contrary to current thinking.

Basal cell carcinoma viewed as a chronic disease for some

Because people who have had multiple bouts of basal cell carcinoma always risk recurrence, the disease can be considered chronic for such patients.

Only a few gene mutations important in leukemia

Most of the hundreds of mutations found in acute myeloid leukemia (AML) genomes occur randomly as part of the aging process, unrelated to cancer.

Protein may predict chemotherapy response in osteosarcoma

The expression of the P16 protein, which inhibits cell growth, may be useful for predicting how osteosarcoma will respond to chemotherapy.

Guidelines: screen for lung cancer with low-dose CT

The American Association for Thoracic Surgery wants annual lung cancer screening for 55-to-79-year-olds with a 30 pack-year history of smoking.

Laxative-free virtual colonoscopy can detect large polyps

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CT colonography can accurately detect adenomas 10 mm or larger in patients who did not undergo laxative-induced bowel cleansing before the procedure.

USPSTF: 'No' for all PSA screening for prostate cancer

USPSTF: 'No' for all PSA screening for prostate cancer

USPSTF has issued a final recommendation against PSA-based screening for prostate cancer for all men, regardless of age.

Younger CRC patients have worse presentation but comparable survival

Colorectal cancer patients under 50 had worse histological characteristics and earlier metastasis but survival equal to or better than older patients.

Diagnosis delayed for certain cancers and certain patients

A large UK study found a wide variation between cancer types in patients who had visited their general practitioner 3 or more times before cancer diagnosis.

Chemoradiotherapy prolongs life for older patients with lung cancer

Survival improved for elderly patients with non-small cell lung cancer who had combined chemotherapy and radiotherapy rather than radiotherapy alone.

CT lung screening useful for some smokers, but drawbacks remain

Annual lung cancer screening with low-dose computed tomography may benefit some smokers, but uncertainty exists as to the harms of screening.

Walking wards off fatigue in pancreatic, periampullary cancers

A home walking program significantly improves fatigue levels and physical functioning in persons with pancreatic and periampullary cancers.

Estrogen use after hysterectomy protects against breast cancer

Women who used estrogen after hysterectomy appear to be nearly 25% less likely to develop breast cancer and nearly 63% less likely to die from it.

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