Cancer In The Elderly
Researchers evaluated whether age is a predictor of pain response after radiotherapy for painful bone metastasis among 128 patients undergoing palliative radiotherapy.
In a single-arm phase 2 study, researchers explored the effectiveness of a modified lenalidomide, bortezomib, and dexamethasone (RVD-lite) regimen in transplant-ineligible patients with multiple myeloma.
Clinicopathological Features and Prognosis in Elderly Gastric Cancer Patients: A Retrospective Cohort StudyApril 27, 2018
[OncoTargets and Therapy] A retrospective study assessed patients with gastric cancer, identifying disease characteristics more prevalent in elderly patients and the effect on prognosis for these patients.
A report on how variations in the effects of geriatric syndromes and aging can affect treatment modality choices and outcomes for the eldest older adults with hematologic cancers.
With median age of participants in clinical trials for soft-tissue sarcoma younger than most patients who develop the disease, these researchers sought to determine the prevalence of including persons older than 65 in clinical trials and the efficacy of first-line chemotherapy for STS in older patients.
This observational study demonstrates the significance of using the chemotherapy toxicity risk score (CTRS) to determine if an elderly patient can safely tolerate standard-dose combination chemotherapy, or would fare better with a reduced-dose regimen.
As supportive care improves, elderly patients may benefit from high-dose chemotherapy with autologous stem cell transplantation.
Feasibility and Outcomes of Modified Enhanced Recovery After Surgery for Nursing Management of Aged Patients Undergoing EsophagectomyJanuary 19, 2018
[Journal of Thoracic Disease] A randomized study investigated whether an mERAS protocol could result in improved recovery of aged patients with esophageal cancer undergoing esophagectomy.
Investigators sought to determine the efficacy of 2-year rituximab maintenance therapy in elderly patients with CLL who achieve a complete response to abbreviated FCR induction therapy.
Using a series of functional tests, researchers determined the significance of sarcopenia severity after chemotherapy in older patients with cancer and its effect on their physical independence.
Researchers conducted a geriatric assessment of 304 patients with cancer, then followed them in a 2-year study to determine the risk of fractures and falls in older patients.
Researchers at Memorial Sloan-Kettering Cancer Center sought to determine if observation status may be a better treatment option for older adults with cancer who present to the ED.
Although use of medical co-management and rehabilitation services increasing for older patients with kidney cancer, consultation remains sparse for those undergoing surgery.
A look at the significant influence of age-adjusted prognoses and treatment priorities for radiation therapy in the oldest patients with cancer.
Roughly half of older Americans experiencing difficulty paying for needed drugs did not talk to their physicians about the issue, poll shows.
Lenvatinib Improves OS, PFS in Radioiodine-Refractory Differentiated Thyroid Cancer in All Older PatientsJune 27, 2017
Results from a sub-analysis of the impact of age on the safety and efficacy of lenvatinib in patients with RR-DTC in the SELECT trial showed that lenvatinib significantly increased PFS.
Prehabilitation before initiating ADT in older men with prostate cancer may improve functioning, even in men on short-term ADT.
Survivorship care plan successfully improves the overall survivorship care of older cancer survivors using lay navigators.
Older cancer survivors typically have higher severity of disease and pre-existing conditions, which makes their cancer treatment additionally challenging. The Patient Care Connect Program was created to help address these issues.
Older adults are underrepresented in clinical trials of cancer drugs, according to study findings presented at the 2017 ASCO Annual Meeting.
Patients aged 80 years and older had a cancer incidence of 16% in 2013 yet made up only 4% of cancer drug clinical trial participants during 2005-2015.
Older patients with cancer most frequently adhere to recommendations to see a dietitian for nutritional issues.
The Coalition for Quality in Geriatric Surgery (CQGS) released its standards of surgical care in older adults with the goal of ensuring high-quality and safe surgical care for older adults in an interdisciplinary setting.
A meta-analysis of elderly patient discharge practices found that including informal caregivers in discharge planning reduces risks of readmission.
The addition of temozolomide to short-course radiotherapy in elderly patients with glioblastoma was associated with some survival benefit compared with radiotherapy alone.
Rosiglitazone has potential for older patients with melanoma who develop resistance to targeted therapies.
Elderly with NSCLC have lower incidence of esophagitis, can tolerate aggressive radiation therapy.
Researchers determined the curative potential of allogenic hematopoetic stem cell transplantation in patients aged 60 years and older with acute myeloid leukemia in second complete remission.
The Patient Care Connect Program lowers Medicare costs and provides other benefits, research indicates.
Using data from previous analyses and several state medical cannabis programs, investigators assessed how social attitudes, health issues, and state laws affect the use of cannabis among persons older than 50 years.
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