Cancer Diagnosis

Cancer diagnosis often adversely affects mental health

Cancer diagnosis often adversely affects mental health

Patients diagnosed with breast cancer, head and neck cancer, and malignant melanoma are particularly at risk for disorders such as anxiety or depression.

Immunosignatures: A powerful, new technique for early diagnosis

Immunosignatures: A powerful, new technique for early diagnosis

Researchers at the Arizona State University Biodesign Institute can developed a new method of early disease detection.

Annual report highlights 2012 cancer advances

The American Society of Clinical Oncology has released a nearly 100-page report detailing the year's most significant developments in cancer.

Three-way approach demystifies kidney cancer

Researchers looking at multiple different levels of changes in renal cell carcinoma are closer to determining how these tumors grow and survive.

Tomosynthesis sharpens digital mammography results

Adding three-dimensional breast imaging to standard digital mammography increases diagnostic accuracy and reduces false-positive recall rates.

Suppressed protein halted melanoma metastasis

Inhibiting one protein eliminated metastasis of melanoma in lab studies, a finding that could lead to targeted therapies for a range of cancers.

High mortality persists for black women with breast cancer

Black women have the highest death rate from breast cancer of all racial and ethnic groups, and are 40% more likely to die of the disease than are white women, according to a new report from the CDC.

Study suggests 10-year colonoscopy rescreen not needed after first negative result

It may be reasonable to use methods other than colonoscopy to rescreen people who had negative results on their first screening colonoscopy.

Expectations too high for palliative chemotherapy

Many persons who receive chemotherapy for incurable cancers may not understand that the treatment is unlikely to be curative.

Measuring water in breast tissue may prevent unnecessary biopsies

Assessing how water moves through breast tissue may reduce false-positive findings among women undergoing dynamic contrast-enhanced MRI.

Quick survey helps uncover ovarian cancer

A simple three-question survey has been developed to help clinicians identify women who may be experiencing symptoms of ovarian cancer.

Use more preop needle biopsy in breast cancer, urge researchers

The quality of breast cancer surgery improved when percutaneous needle biopsy was performed preoperatively.

HF/CM risks in breast chemotherapy

HF/CM risks in breast chemotherapy

Earlier study findings that anthracycline- or trastuzumab-based treatment for breast cancer raises the risk for heart failure and cardiomyopathy can be extended to a more general population of women.

Race and socioeconomics impact emergency colorectal cancer diagnosis


Among patients with colorectal cancer, 29% in a nationally representative sample were diagnosed after an emergency, such as an obstruction or perforation of the bowel.

Watchful waiting offers more quality years than prostatectomy

Compared with prostatectomy, surveillance will likely reduce prostate cancer-specific survival only slightly and greatly enhance quality of life.

Special ultrasound device approved for dense breasts

The somo-V Automated Breast Ultrasound System received FDA approval for use in combination with standard mammography in women with dense breast tissue.

Split-dose prep improves colonoscopy

Dividing bowel preparation solution into two doses resulted in better preparation quality, detection rates, and colonoscopy completion rates.

Patient navigation services improve time to diagnosis and care for vulnerable patients


For female patients with an abnormal breast or cervical cancer screening result, patient navigation services help to decrease the time to diagnosis and helps vulnerable populations get the care they need in a timely manner.

HPV alone not a reliable marker of HPV-driven head/neck cancers

Human papillomavirus (HPV) positivity alone is a poor biomarker for HPV-driven head and neck cancers, according to two recent studies.

Breath test can indicate lung cancer

An analysis of breath samples from patients with pulmonary nodules distinguished benign from malignant growths in a recent study.

Diagnosis and surgery for prostate cancer reduces quality of life


One year after men undergo surgical removal of prostate cancer, they have significant anxiety, which appears to be linked to poor sexual satisfaction and depression.

Children with acute myeloid leukemia benefit from improved diagnostic test


Flow cytometry has been identified as better for checking for minimal residual disease than two other widely used methods to predict patient survival.

Excess weight bodes poorly for HR-positive breast cancer

Overweight and obese women with hormone receptor (HR)-positive operable breast cancer have an increased risk of disease recurrence and death.

Multiple tumors worsen glioblastoma prognosis

Persons with more than one glioblastoma tumor upon diagnosis experience significantly worse survival than do patients with a solitary lesion.

Risk model finds best candidates for lung cancer CT screening

A lung cancer risk-prediction model effectively identified individuals who would benefit most from low-dose computed tomography (CT) screening.

PSA era sees improved overall survival rates in prostate cancer

Overall survival rates have improved for men with prostate cancer following the introduction of PSA screening, particularly for African Americans.

Finasteride, dutasteride therapy may enhance PSA reading

The magnitude of change in serum prostate-specific antigen (PSA) after 5α-reductase inhibitor therapy may be useful in diagnosing prostate cancer.

Basal cell carcinoma viewed as a chronic disease for some

Because people who have had multiple bouts of basal cell carcinoma always risk recurrence, the disease can be considered chronic for such patients.

Recommendations for management of esophageal precancer, cancer

Recommendations for management of esophageal precancer, cancer

Good endoscopic equipment, endoscopic surgery, and good tissue samples are key to diagnosing and managing esophageal conditions.

FDA Update - July/August 2012

News about pertuzumab injection (Perjeta); ondansetron (Zofran); carfilzomib (Kyprolis); Therascreen KRAS RGQ PCR Kit; Prostate Health Index (phi); and Prepopik

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