Researchers assessed shoulder mobility after breast-conserving surgery, comparing results after node-negative and node-positive treatment protocols and healthy controls.
Potential Clinically Useful Prognostic Biomarkers in Triple-negative Breast Cancer: Preliminary Results of a Retrospective Analysis
[Breast Cancer: Targets and Therapy] This research examines possible core biomarkers for triple-negative breast cancer.
Researchers sought to determine if the complementary practice could prevent CIPN in patients receiving adjuvant chemotherapy for breast cancer.
Study findings measure quality of life for pregnant patients with breast cancer and reveals the effectiveness of disease-specific assessment tools.
Study measures the usefulness of systemic imaging in early-stage breast cancer.
Few women aged 70 and older with breast cancer undergo postmastectomy breast reconstruction due to potential complications; however, these patients are not less likely to have good outcomes.
Researchers sought to determine how subjective measures of CIPN correlated with objective measures of CIPN.
Pilot study sought to determine risk of breast cancer among African American women veterans.
[Breast Cancer: Targets and Therapy] Researchers examined chemerin expression in tissue with immunohistochemistry and analyzed the association of chemerin expression with the patients' clinical characteristics to determine its role as a predictor of the disease and its relation to disease prognosis.
In a 2-pronged study, researchers determined that antiperspirant/deodorant use is a significant part of quality of life for patients with breast cancer, and the practice does not increase risk of skin reactions in the axilla.
Using data from the phase 3 trial CALGB 40101, researchers determined the risk for chemotherapy-induced neuropathy among patients with early-stage breast cancer receiving adjuvant paclitaxel weekly or biweekly.
Higher recurrence risk linked to older age, more advanced stage, HR-negative tumors.
A retrospective study sought to determine the effectiveness of surgical intervention for elderly female nursing home residents with breast cancer.
Assessment of a subgroup of a cohort study revealed that many patients undergoing tamoxifen therapy for early-stage breast cancer do not adhere to their prescribed treatment, even though they claim adherence on patient surveys.
Atezolizumab plus nab-paclitaxel prolongs progression-free survival in metastatic disease.
Researchers surveyed 60 breast cancer survivors to determine if their desire to achieve pregnancy had changed after completing treatment. These findings were presented at ESMO 2018 Congress.
Study findings presented at ESMO 2018 Congress revealed the effect of a shorter, 9-week course of trastuzumab on disease-free survival (DFS) and cardiac toxicity in women with HER2-positive breast cancer.
Researchers conducted a retrospective study to develop a DL algorithm to assess mammographic breast density.
A study from the Instituto Nacional de Cancerología demonstrated a potential need for education on fertility and contraceptive use among young women with breast cancer.
A review of the most feared effects of breast cancer treatment and resources to recommend to patients coping with these effects.
Thinking and Living With Cancer (TLC) sought to determine the effects of breast cancer treatment and age on cognitive function in older breast cancer survivors over time.
Hypofractionated Radiotherapy After Conservative Surgery May Increase Low-intermediate Grade Late Fibrosis in Breast Cancer Patients
[Breast Cancer: Targets and Therapy] Researchers sought to determine the incidence of subcutaneous side effects in patients with early-stage breast cancer treated with AHF-RT vs standard fractionated RT after breast conserving surgery.
Pros and cons of increased breast cancer screening in women with dense breasts are presented by experts.
[Cancer Management and Research] Data from a total of 16,998 patients with breast cancer included in the SEER database were evaluated to determine the prognosis of various treatment options for elderly patients.
Researchers have linked weight loss with a lower risk of breast cancer in postmenopausal women.
Researchers are seeking genetic biomarkers that can predict which patients are most likely to suffer radiotoxicities and which can safely undergo intensified radiation treatment regimens.
A retrospective, observational study investigated the impact of obtaining a second opinion of a breast cancer diagnosis from a multidisciplinary tumor board.
Self-care toolkits were found to reduce pain and other negative postsurgical experiences for women undergoing surgical procedures for breast cancer.
Researchers present a review of postmastectomy breast reconstruction options and patient preferences.
[Breast Cancer: Targets and Therapy] This research examines the mechanism of action of L-DOX and its most common side effects and highlight results of its use in clinical trials for the treatment of BC as single agent and in combination with other commonly used chemotherapeutics.
Results of an electronic survey of women with a history of stage 0-III breast cancer revealed patients' preferences for including costs when discussing treatment options with their cancer care team.
An examination of the parameters of a cell's nucleus can help identify the molecular markers of breast cancer tumors.
A study presented at 2018 ASCO Quality Care Symposium demonstrates further support for Choosing Wisely Initiative's recommendations against routine scanning in early-stage breast cancer.
Trastuzumab and certain chemotherapy treatments can increase patient risk of heart failure.
The MSP in Germany is designed to detect breast cancer during annually scheduled screenings and between the last negative and following screening among survivors.
Long-term Survival Effect of the Interval Between Mastectomy and Radiotherapy in Locally Advanced Breast Cancer
[Cancer Management and Research] Retrospective study investigates the effect of radiotherapy on long-term survival in patients who underwent mastectomy for breast cancer at various time intervals.
Investigators examined the impact of online symptom self-management on chronic pain symptoms associated with breast cancer survivorship.
Tamoxifen or exemestane plus ovarian suppression more effectively increases survival than tamoxifen alone for premenopausal women with breast cancer.
In a randomization of women with early-stage breast cancer, researchers explored the potential benefits of chemotherapy for women whose Oncotype DX RS was midrange.
Using 2 established sexual function questionnaires, researchers evaluated the effect of breast cancer treatment on sexual quality of life for survivors of the disease.
Digital mammography and tomosynthesis proved superior to digital mammography alone, according to a study.
Guideline recommends therapies for reducing anxiety/stress, depression/mood disorders, nausea
CDC investigators found that from 2000 to 2015, screening for breast, cervical, and prostate cancers decreased significantly.
Screening practices and smoking habits are expected to have a significant impact on mortality rates for lung cancer and breast cancer among women in high-income countries.
This fact sheet reviews Paget disease of the breast symptoms, diagnosis, and treatments.
In a multicenter study, researchers sought to determine if acupuncture effectively relieved aromatase inhibitor-related joint pain in patients with breast cancer.
Researchers sought to determine if men with prostate cancer would derive the same benefits from hypnosis as women with breast cancer. Their results highlight significant differences in what is helpful for men vs women.
Pooled analysis finds levels 60 ng/mL are most protective among women aged 55 years and older
A systematic review of 36 studies evaluated their findings to determine an overall effect of various types of exercise on quality of life for breast cancer survivors.
Survey responses revealed that clinicians and patients do not agree on whether discussions regarding the impact of treatment on employment and/or financial status occur or are helpful.
A population-based, case-control study identified a link between timing of meals and interval between last meal and sleep with risk of cancer, particularly of the breast and prostate.
A prospective trial with more than 2000 women who underwent mastectomy with immediate breast reconstruction sought to determine patient satisfaction with their breasts and quality of life annually over 4 years after their procedure.
In this study, researchers sought to determine if a genetic predisposition to depression exists in some patients with breast cancer and how to identify it.
Weight loss associated with bariatric surgery could reduce risk of hormone-related cancers, but an increased risk for colorectal cancer was seen in patients who underwent gastric bypass.
Researchers sought to determine if handgrip force could provide objective measures of CRF in patients with cancer.
Higher rate of recall, lower sensitivity, larger tumor diameter, and more lymph node-positive disease observed in women with dense breasts.
Combined Microwave Ablation and Minimally Invasive Open Decompression for the Management of Thoracic Metastasis in Breast Cancer
[Cancer Management and Research] An investigation into the efficacy of microwave ablation and minimally invasive open decompression treatment for breast cancer with thoracic metastases.
Researchers report on a study to determine the relationship between BMI and risk for breast cancer among younger women, particularly those 18 to 24 years old.
FDA-approved oral and injectable treatment options for breast cancer.
Is trastuzumab classified as an immunotherapy? If so, how does it work?
Creating a multidisciplinary breast clinic can ensure that patients with breast cancer receive care that is timely, effective, and efficient, according to a presentation at the 2018 ONA Navigation Summit.
Marissa Fors, director of CancerCare's Susan G. Komen® Breast Care Helpline, talked with Dr Penelope Damaskos, of Memorial Sloan Kettering Cancer Center, about breast cancer risk and related challenges for women who identify as lesbian and their healthcare providers.
A sizable number of breast cancer survivors do not undergo annual surveillance.
Researchers explored connections between overall survival and adjuvant radiotherapy when factoring in CTC status.
A personalized therapy can mediate complete durable cancer regression, according to study results.
In a retrospective study, researchers investigated the effect of primary prophylaxis on incidence of febrile neutropenia in patients with early stage breast cancer.
A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.
Study results presented at 2018 ASCO Annual Meeting demonstrated effectiveness of ado-trastuzumab emtansine in non-breast non-gastric HER2-amplified cancers.
In a multicenter phase 2 study, the Walk With Ease program was evaluated for its effectiveness in reducing radiotherapy-associated fatigue vs usual care in older patients with breast cancer. Results were presented at 2018 ASCO Annual Meeting.
Sarcopenia and adiposity measures may help clinicians steer management strategies for some patients with breast cancer.
Long-term analysis determined the effect of postadjuvant dose-dense chemotherapy on DLCO among women with breast cancer.
Survey results presented at the 2018 ASCO Annual Meeting demonstrated the effects of financial toxicity on patients with early stage breast cancer.
In a follow-up to the Women's Health Initiative study, researchers determined the effect of a low-fat diet on overall survival after a breast cancer diagnosis.
Computer analysis is not better than human clinical evaluation when it comes to measuring breast density
1. Similar associations were observed with clinical BI-RADS and automated BI-RADS with respect to interval and screen-detected cancer. 2. Both automated and clinical BI-RADS showed similar discriminatory accuracy and mammography accuracy. Evidence Rating Level: 2 (Good) Study Rundown: In the United States, the standard for monitoring breast density is through the Breast Imaging Reporting and 
A review of HER2-positive breast cancer, including etiology, diagnosis, and treatments.
Survivorship plans for adolescent and young adult survivors need to consider the relative long-term survival for AYAs with certain cancers. Those with certain cancers may have excess long-term mortality.
Researchers discovered that the likelihood of a poor prognosis was increased for cases of cancer diagnosed after screening mammography with negative results versus those diagnosed after mammography with positive results.
A review of surveillance mammography demonstrated the potential value of these images in post primary therapy treatment of women with breast cancer.
The researchers found that the choice to undergo future screenings appeared to be influenced by previous false-positive results for both men and women.
A review of the literature on follow-up after positive screening results led researchers to a consensus opinion on timing of diagnostic tests for 4 cancers: breast, cervical, colorectal, and lung.
A randomized study assessed the effectiveness of an Internet-based psychological intervention in helping women survivors of breast cancer cope with the changes brought by their disease and treatment.
In a study that evaluated outcomes for younger, working age women with breast cancer, researchers identified differences in cancer-related financial adverse events in black women vs white women.
A logistic regression analysis determined the effect receiving a false-positive result had on future participation in cancer screenings.
[Breast Cancer: Targets and Therapy] Researchers present a review of the LHRH agonist triptorelin and the use of this agent to induce chemical castration in estrogen-sensitive breast cancer tumors in younger women.
In this open label phase 2 BOLERO-4 study, researchers evaluated the effect of everolimus plus endocrine therapy on progression-free survival.
A model that incorporates HRQOL was found to outperform a model that only employs traditional prognostic variables.
A study using a cohort of women from Kaiser Permanente Washington evaluated the accuracy of risk assessment models for breast cancer that included classic risk factors with and without breast density as an additional factor during more than 10 years of follow-up.
A retrospective cohort study of data from the SEER database assessed the potential risk of cardiac-related mortality in patients with breast cancer, treated with chemotherapy or radiotherapy, vs the general population.
Researchers reviewed 48 cases of patients with prior breast augmentation undergoing breast cancer treatment to determine detection rate and treatment choices.
Researchers sought to determine the benefit of managing microinvasive breast cancer similarly to invasive tumors in a retrospective study.
Advances in breast imaging such as DBT offer better, clearer images of breast tissue that can identify even low-grade DCIS tumors. But will more sensitive imaging lead to improved outcomes or increased overtreatment?
Male spouse or partner perspectives on a female patient's ability to cope was found to have a positive effect on her ability to cope and adjust to her disease. Unfortunately, this effect remains rarely researched and poorly understood among patients with breast cancer in same sex relationships.
Results of a prospective study of patients with breast or prostate cancer demonstrate the impact of taxane-based chemotherapy on quality of life.
[Breast Cancer: Targets and Therapy] In this retrospective analysis of medical records and estimated costs of treatment, investigators demonstrated that rapid change based on level I evidence is feasible.
Researchers assessed outcomes of elderly patients with breast cancer to identify the correlation between cardiovascular disease risk factors and overall survival in survivors older than 66.
Pooled analysis indicated that schizophrenia was associated with a significantly increased risk of breast cancer incidence in women, but researchers had some reservations with the results.
The US FDA has approved a consumer test that may indicate increased breast and ovarian cancer risk in some individuals.
Results of a prospective study demonstrated the effectiveness of a 1-hour psychoeducational intervention designed to help survivors of breast cancer manage their chemotherapy-related cognitive dysfunction and improve their memory contentment.
An analysis of SEER data sought to examine the appropriateness of age- and race-specific breast cancer screening recommendations for white vs nonwhite women in the United States.
At $225 million per system, the precision of proton beam radiotherapy is not necessarily overshadowing its high costs. Yet ongoing studies seek to determine how this technology fits into current treatment regimens for prostate, breast, and other cancers.
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