Brain Cancer section

Brain Cancer News and Features

CNS Tumors in Childhood: Predicting Successful Independence in Adult Life

CNS Tumors in Childhood: Predicting Successful Independence in Adult Life

Researchers at St Jude Children's Research Hospital sought to determine what indicators in survivors of CNS tumors can predict the survivor's ability to live independently as an adult.

Durable Response Achieved With Nivolumab in Untreated Melanoma Brain Metastases

Durable Response Achieved With Nivolumab in Untreated Melanoma Brain Metastases

In this phase 2 study, researchers randomly assigned 79 patients with immunotherapy-naive melanoma with brain metastases to receive either nivolumab plus ipilimumab or nivolumab alone.

Prognostic Significance of Epidermal Growth Factor Receptor Expression in Glioma Patients

Prognostic Significance of Epidermal Growth Factor Receptor Expression in Glioma Patients

[OncoTargets and Therapy] A meta-analysis was conducted to evaluate the effect of abnormal EGFR expression on overall survival (OS) in patients with glioma.

Tumor-treating Fields Useful to Improve Glioblastoma Outcomes

Tumor-treating Fields Useful to Improve Glioblastoma Outcomes

Adverse event rates were similar in both trial groups, though patients treated with TTFields were much more likely to have mild to moderate skin toxicity.

History of Headache, Vomiting, Seizures Associated With Pediatric Brain Cancer

History of Headache, Vomiting, Seizures Associated With Pediatric Brain Cancer

Research pinpointed clinical factors, such as headache, that may be associated with pediatric brain neoplasms.

Brain Cancer Clinical Trials

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

As immunotherapies gain a stronger foothold as a treatment option for cancer, ASCO and SITC convened a panel to develop recommendations to ensure consistent and efficient clinical trial reporting in immuno-oncology.

Progression free survival poorly correlates with health-related quality of life in cancer trials

1. Progression free survival demonstrates poor-correlation with measures of health related quality of life (HRQoL) in oncology trials. 2. Current study demonstrate poor follow-up and reporting of HRQoL measures, likely introducing bias into published results. Evidence Rating Level:3 (Average) Study Rundown: Current stated goals for the American Society of Clinical Oncology include the focus on []

Delphi Panel Presents Recommendations for Expanding Role of Patients in Research

A Delphi panel developed recommendations for integrating patients, as well as caregivers and advocate, a greater role in medical research while maintaining scientific integrity of studies.

CNS Tumors in Childhood: Predicting Successful Independence in Adult Life

Researchers at St Jude Children's Research Hospital sought to determine what indicators in survivors of CNS tumors can predict the survivor's ability to live independently as an adult.

ASCO Roundtable Addresses Clinical Trial Financial Burdens

The American Society of Clinical Oncology hosted a roundtable to develop recommendations targeted at improving patients' out-of-pocket costs for clinical trial participation.

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