Drug Name:
BONJESTA Rx
Generic Name and Formulations:
Doxylamine succinate 20mg, pyridoxine HCl 20mg; ext-rel tabs.
Company:
Duchesnay USA, Inc.
Therapeutic Use:
RECENT UPDATES
Monograph added.Indications for BONJESTA:
Treatment of nausea and vomiting of pregnancy (NVP) in women who do not respond to conservative management.
Limitations Of use:
Not studied in women with hyperemesis gravidarum.
Adult:
Swallow whole. Take on empty stomach with water. ≥18yrs: Day 1: initially 1 tab at bedtime; continue same dose next day if symptoms adequately controlled. If symptoms persist on Day 2, increase to 1 tab in AM and 1 tab at bedtime daily. Max 2 tabs daily.
Children:
<18yrs: not established.
Contraindications:
Concomitant MAOIs; may prolong and intensify anticholinergic effects.
Warnings/Precautions:
Asthma. Increased intraocular pressure. Narrow angle glaucoma. Stenosing peptic ulcer. Pyloroduodenal obstruction. Urinary bladder-neck obstruction. Reevaluate as pregnancy progresses. Nursing mothers: not recommended.
Interactions:
See Contraindications. Concomitant alcohol, other CNS depressants (eg, hypnotic sedatives, tranquilizers): not recommended. Concomitant food may delay onset of action and reduce absorption.
Pharmacological Class:
Antihistamine + Vit. B6 analog.
Adverse Reactions:
Somnolence.
Generic Availability:
NO
How Supplied:
Tabs—60, 100
Sign Up for Free e-newsletters
ONA Articles
- Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma
- Challenges for Young Adult Couples Facing a Cancer Diagnosis
- Progression-Free Survival Extended With PANEX Protocol in R/R Multiple Myeloma
- Redefining Prognosis for Hematologic Cancers in Older Adults by Age
- Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors
- Letter-Writing Project Communicates Care Wishes to Healthcare Team, Family
- Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care
- Long-term Carfilzomib May Be Safe, Effective In Relapsed Multiple Myeloma
- Palliative Sedation a Valid Option for Refractory Symptoms in End-stage Cancer
- Testicular Cancer Treatment May Increase Risk for Heart Disease in Survivors
- Spotlight on Triptorelin in the Treatment of Premenopausal Women with Early-Stage Breast Cancer
- Redefining Prognosis for Hematologic Cancers in Older Adults by Age
- Outcomes for Elderly With Hematologic Cancers Effected by Cognitive Impairments
- Evolving Role of Radiation Therapy in the Treatment of Mesothelioma
- FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
| Bone Cancer | Regimens | Drugs |
| Brain Cancer | Regimens | Drugs |
| Breast Cancer | Regimens | Drugs |
| Endocrine Cancer | Regimens | Drugs |
| Gastrointestinal Cancer | Regimens | Drugs |
| Genitourinary Cancer | Regimens | Drugs |
| Gynecologic Cancer | Regimens | Drugs |
| Head and Neck Cancer | Regimens | Drugs |
| Hematologic Cancer | Regimens | Drugs |
| Lung Cancer | Regimens | Drugs |
| Other Cancers | Regimens | |
| Rare Cancers | Regimens | |
| Skin Cancer | Regimens | Drugs |