Specialized fat molecules, called sphingolipids, play a key role in the survival of aggressive lymphomas caused by viruses, according to new research.
This fact sheet provides an overview of how the immune system functions and examines biological therapies, including monoclonal antibodies, cytokines, therapeutic vaccines, cancer-killing viruses, gene therapy, and adoptive T-cell transfer as well as side effects.
This activity from myCME offers a review of groundbreaking molecular research and novel treatment options for patients with NSCLC.
Molecules in the bloodstream that might accurately gauge the likelihood of radiation illness after exposure to ionizing radiation have been identified. This animal study shows that X-rays or gamma rays alter the levels of certain molecules called microRNA (miRNA) in the blood in a predictable way.
Ibrutinib, which targets the Bruton's tyrosine kinase to combat chronic lymphocytic leukemia, showed promising results in two phase II studies.
Electrically-conductive polymers, commonly used in solar energy applications, have been modified so that infrared light causes them to generate heat that can be used to kill colorectal cancer cells.
A fusion gene that is responsible for 30% of a rare subtype of childhood leukemia with an extremely poor prognosis has been identified. This finding offers the first evidence of a mistake that gives rise to a significant percentage of acute megakaryoblastic leukemia cases in children.
French researchers are taking advantage of the progress in genetic and molecular profiling to analyze the make-up of the tumors of individual cancer patients and then using the information to assign patients to particular treatments and phase I clinical trials.
A combination of chemotherapy and immunotherapy appears to be a labor-intensive but feasible treatment for persons with metastatic melanoma.
A therapeutic vaccine for women who are already harboring human papillomavirus (HPV) appeared to fight cervical cancer in a small, phase 1 study.
Melanoma cells are able to build up tolerance to chemotherapy by means of a genetic pathway that inhibits their detection of DNA damage.
Many potential targets for squamous cell lung cancer (SCLC) have been identified by The Cancer Genome Atlas (TCGA). The study involved a team of researchers from throughout the United States, plus the British Columbia Cancer Agency in Vancouver, British Columbia, Canada.
Subcutaneous delivery of trastuzumab (Herceptin) appears to be as safe and effective as the much more time-consuming intravenous system.
News about pertuzumab injection (Perjeta); ondansetron (Zofran); carfilzomib (Kyprolis); Therascreen KRAS RGQ PCR Kit; Prostate Health Index (phi); and Prepopik
Mice without the genes responsible for the development of the T helper 17 (TH17) cell demonstrated significant resistance to melanoma tumor growth.
Researchers are investigating the use of genomics to achieve better cure rates with less morbidity in patients undergoing radiation treatment.
Combination therapy may be a promising treatment approach for patients with advanced melanoma who experience the abscopal effect.
A long-term study indicated that imatinib is the treatment of choice for people with chronic myeloid leukemia who do not respond to interferon.
A recent trial indicates that a viral therapy delivered intravenously can consistently infect and spread within tumors without harming normal tissue in humans.
Women recovering from breast cancer choose biological-based therapies, according to findings published in Nursing Research (2010 Jan-Feb;59(1):58-66).
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