Microscopic Polyangiitis
Are You Confident of the Diagnosis? Microscopic polyangiitis (MPA) is a systemic small vessel vasculitis, which, although primarily associated with necrotizing and crescentic glomerulonephritis and pulmonary capillaritis, often has cutaneous and musculoskeletal features. MPA is a member of the family of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides and is strongly associated with antimyeloperoxidase (MPO)-ANCA. Characteristic findings…