Adverse Effects
Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT
August 16, 2018Researchers sought to determine if NMA or reduced-intensity conditioning with busulfan improved severity/duration of oral mucositis compared with myeloablative conditioning in patients with hematologic cancer undergoing HCT.
FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma
August 14, 2018The manufacturer of daratumumab, a CD38-directed antibody for the treatment of multiple myeloma, has submitted a sBLA and a type II variation to the US FDA and European Medicines Agency, respectively, for approval of a split dosing regimen.
8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers
August 14, 2018In an open-label study, researchers sought to determine the optimal amount of bed rest after intrathecal chemotherapy for patients with hematologic cancers.
Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma
August 10, 2018In a systematic review, researchers explored the financial burden of treating grade 3 to 4 adverse events associated with melanoma and its treatment.
Healthcare Use, Economic Burden Greater With Cancer-Related Opioid-Induced Constipation
August 03, 2018Use of opioids to manage cancer-related pain may have adverse effects of its own that can have a significant impact on healthcare use among patients with cancer.
Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma
July 18, 2018In an analysis of 11 studies, researchers investigated whether the benefits of carfilzomib for multiple myeloma outweigh the cardiovascular risks. However, the researchers recommend careful monitoring and management of blood pressure and volume status as good clinical practice, regardless.
Genetic Link Between Depression and Breast Cancer Remains Unclear
July 17, 2018In this study, researchers sought to determine if a genetic predisposition to depression exists in some patients with breast cancer and how to identify it.
Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer
July 06, 2018In a randomized study, researchers sought to determine the effect of IV injections of coix seed oil, a Chinese CAM, on pain and quality of life measures for patients with advanced cancer.
Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue
July 05, 2018Researchers sought to determine if handgrip force could provide objective measures of CRF in patients with cancer.
CALM: A Depression Intervention for Cancer Patients at the End of Life
July 03, 2018The effectiveness of a novel intervention intended to reduce and/or prevent depression in patients with advanced cancer at the end of life was investigated in a randomized study with more than 300 patients.
Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress
July 02, 2018Mindfulness-based interventions are proven effective in helping patients with cancer manage distress and other psychological symptoms. In this study, researchers sought to determine if Internet-based MBCT can be as effective as face-to-face interventions.
PTSD May Increase Symptom Burden in Patients With Cancer
July 02, 2018Post-traumatic stress symptoms are linked to a greater symptom burden in hospitalized cancer patients.
Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life
June 29, 2018In this retrospective study, researchers sought to determine the effectiveness of fentanyl for dyspnea in dying patients with advanced cancer.
Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer
June 28, 2018In a retrospective study, researchers used established tools to measure the nutritional status of patients with head and neck cancer before, immediately after, and at 2 follow-up points after radiotherapy.
Ixazomib, Lenalidomide, Dexamethasone Effective But Increases Toxicity in Multiple Myeloma
June 27, 2018Three-drug regimen twice a week achieved good response and long-term outcomes in patients with newly diagnosed multiple myeloma; however, regimen has higher toxicity than once weekly dose.
Low-Dose Dasatinib for Chronic-Phase CML Safe, Effective With Fewer Adverse Events
June 25, 2018In this study, researchers assigned 75 patients with newly diagnosed Philadelphia chromosome (Ph)-positive CML-CP to receive dasatinib 50 mg once daily.
Childhood Neuroblastoma Survivors at Risk for Psych Impairment
June 19, 2018Psychological impairment seen particularly in survivors with chronic health conditions.
Navigating the Benefits and Challenges of Immunotherapy
June 15, 2018A review of immunotherapy — what they are, how they work, and what to watch for — was presented at the 2018 ONA Navigation Summit.
Muscle Loss Not Always Correlated With Loss of Function, Strength in Cancer Cachexia
June 12, 2018Interventions specifically designed to target cachexia in patients with thoracic or gastrointestinal cancer and established cachexia were effective in helping patients preserve functional stability and rehabilitation potential.
Association Between Multiple Myeloma With VTE and Increased Mortality at 2, 5 Years
June 11, 2018A study presented at the 2018 ASCO Annual Meeting investigated the mortality risk for patients with multiple myeloma who develop VTE.
Primary Prophylaxis Key in Reducing Febrile Neutropenia in Early Breast Cancer
June 07, 2018In a retrospective study, researchers investigated the effect of primary prophylaxis on incidence of febrile neutropenia in patients with early stage breast cancer.
Head and Neck Cancer Survival Improved When irAEs Occur During Anti-PD-1 Therapy
June 06, 2018Researchers evaluated whether the development of irAEsc among patients with metastatic head and neck cancer who have failed platinum-based chemotherapy could improve patient outcomes.
Palliative Issues Inadequately Addressed Among Hospitalized Cancer Patients
June 04, 2018Consultations for palliative care for hospitalized highly symptomatic patients with cancer is low regardless of curability or whether patient has hematologic or solid cancer, a study presented at 2018 ASCO has shown.
Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer
May 31, 2018In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.
Patient Advocacy, Questioning 'Status Quo,' Improves Safety in Ambulatory Infusion Setting
May 23, 2018In fielding reports of CNS-related adverse effects from patients in the ambulatory infusion room, nurses were able to prompt a pharmacy practice review. The outcomes of the resulting switch in premedication for HSR was presented at the 2018 ONS Annual Congress.
Peripheral Neuropathy Frequent for Childhood Cancer Survivors
May 22, 2018Long-term neurotoxicity was more frequently seen with cisplatin than with vinca alkaloids, data indicates.
NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes
May 22, 2018A clinic staffed with clinical research nurses provided needed care for patients in clinical trials who experienced adverse effects, and also ensured consistent documentation of treatment-related AEs, according to a presentation at the 2018 ONS Annual Congress.
Simple Adjustment Key to Paclitaxel Infusion Protocol That Reduced Hypersensitivity Reactions
May 20, 2018A project presented at the 2018 ONS Annual Congress demonstrated the effectiveness of standardizing nursing practices for paclitaxel infusions.
Posttreatment Visual Function, Ocular Symptoms Impact QOL in Head and Neck Cancer
May 18, 2018A link between visual function, ocular symptoms, and quality of life was found in cross-sectional study of patients who underwent radiotherapy for head and neck cancers, according to a presentation at the 2018 ONS Annual Congress.
Electronic Self-Report Assessment-Cancer May Preserve Physical Function in Chemotherapy-Induced Peripheral Neuropathy
May 18, 2018Research presented at the 2018 ONS Congress reported on the effectiveness of ESRA-C, a web-based assessment and self-care intervention program, in the management of CIPN in patients receiving platinum and/or taxane-based chemotherapy.
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ONA Articles
- New PDL1 Inhibitors for Non-small Cell Lung Cancer: Focus on Pembrolizumab
- FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma
- Adhering to Cytoreductive Therapy Use May Improve Outcomes in Polycythemia Vera
- Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma
- Hope, Gratitude, and Spirituality: What They Mean to Cancer Patients
- NCCIH HerbList App Launched to Provide Information on Herbal Products
- Seeking Reliable Information on Herbal Products
- Metformin Use May Improve Survival Outcomes in Bladder Cancer
- Higher Vitamin D Levels Associated With Lower Breast Cancer Risk
- Nurse-Led Program Improves Health, Financial Outcomes in Outpatient Chemotherapy
- Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT
- Alternate Dosing of Ruxolitinib May Alleviate Anemia in Myelofibrosis
- Adhering to Cytoreductive Therapy Use May Improve Outcomes in Polycythemia Vera
- Disparities Remain in Prevalence of Cancer Screening Tests
- Hope, Gratitude, and Spirituality: What They Mean to Cancer Patients
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