[Cancer Management and Research] A single-institution study that evaluated the efficacy and safety of apatinib, a specific TKI, in patients aged 16 years and older with advanced osteosarcoma progressing on chemotherapy showed that some AEs may be markers for improved PFS and clinical benefit rate.
[Cancer Management and Research] Despite the efficacy of radiotherapy, response to treatment can vary by breast cancer subtype and type of therapy. In this review, researchers summarize the prognostic differences and discuss potential reasons for them.
[OncoTargets and Therapy] While multimodal treatment can be curative in select cases of r/r pediatric sarcoma, treatment refractoriness remains a tremendous hurdle for clinicians.
[Breast Cancer: Targets and Therapy] A review of conventional and novel therapies for breast cancer, as well as an investigation into the role of breast cancer stem cells in treatment resistance and what’s in the pipeline to combat that resistance.