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ZINPLAVA
Diarrhea
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Drug Name:

ZINPLAVA Rx

Generic Name and Formulations:
Bezlotoxumab 25mg/mL; soln for IV infusion after dilution; preservative-free.

Company:
Merck & Co., Inc.

Therapeutic Use:

Indications for ZINPLAVA:

To reduce recurrence of Clostridium difficile infection (CDI) in patients who are receiving antibacterial drug treatment of CDI and are at high risk for CDI recurrence.

Limitations Of use:

Not for treating CDI. Use only in conjunction with antibacterial drug treatment of CDI.

Adult:

Infuse over 60mins. ≥18yrs: a single dose of 10mg/kg.

Children:

<18yrs: not established.

Warnings/Precautions:

History of CHF. Pregnancy. Nursing mothers.

Pharmacological Class:

Human IgG1 monoclonal antibody.

Adverse Reactions:

Nausea, pyrexia, headache, infusion-related reactions; heart failure.

Generic Availability:

NO

How Supplied:

Single-dose vial (40mL)—1

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