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ZEBETA
Hypertension
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Drug Name:

ZEBETA Rx

Generic Name and Formulations:
Bisoprolol (as fumarate) 5mg+, 10mg; tabs; +scored.

Company:
Teva Pharmaceuticals

Therapeutic Use:

Indications for ZEBETA:

Hypertension.

Adult:

5mg once daily; max 20mg once daily. Renal or hepatic dysfunction, or bronchospastic disease: initially 2.5mg once daily.

Children:

Not recommended.

Contraindications:

Cardiogenic shock. Overt heart failure. 2nd- or 3rd-degree AV block. Marked sinus bradycardia.

Warnings/Precautions:

CHF. Angina. Peripheral vascular disease. Asthma. COPD. Surgery. Diabetes. Thyroid disease. Hepatic or renal impairment. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Additive effects with reserpine, guanethidine, other catecholamine depleting drugs, calcium channel blockers, antiarrhythmics, myocardial depressants. Increased rebound hypertension with clonidine withdrawal. Antagonized by rifampin. May block epinephrine.

Pharmacological Class:

Cardioselective beta-blocker.

Adverse Reactions:

Headache, fatigue, GI upset, upper respiratory symptoms (eg, cough, dyspnea, rhinitis), chest pain.

How Supplied:

Tabs—30

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