Year In Review ONA

Prosthetic Nipple Crowns Survivor's Quest for Improved Breast Reconstruction

Prosthetic Nipple Crowns Survivor's Quest for Improved Breast Reconstruction

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When her search for a realistic nipple to complete her breast reconstruction alluded Michelle Kolath-Arbel, a breast cancer survivor, she decided to make one herself.

Navigating the Transition From Treatment to Breast Cancer Survivor

Navigating the Transition From Treatment to Breast Cancer Survivor

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The transition from active treatment to survivorship for patients with breast cancer can be as complex as the disease. An oncology social worker discusses the challenges of this "new unknown" in the continuum of care.

Breast Cancer Recurrence Not a Deterrent for Survivors Who Wish to Conceive

Breast Cancer Recurrence Not a Deterrent for Survivors Who Wish to Conceive

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This study explored the potential for pregnancy and breastfeeding among women who survived breast cancer, particularly those with ER-positive disease, and the impact of pregnancy on disease recurrence.

Options Available for Estrogen Depletion After Breast Cancer

Options Available for Estrogen Depletion After Breast Cancer

Women should be encouraged to optimize lifestyle and should not generally be treated with hormone therapy following breast cancer.

Perioperative Blockade of Pathways May Improve Outcomes in Breast Cancer

Perioperative Blockade of Pathways May Improve Outcomes in Breast Cancer

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Blocking the beta-adrenergic and COX-2 pathways in the perioperative period may inhibit cellular and molecular pathways associated with metastasis and disease recurrence in patients with early stage breast cancer.

One-Quarter of Patients With Early Breast Cancer Strongly Consider CPM

One-Quarter of Patients With Early Breast Cancer Strongly Consider CPM

A majority of patients with early-stage breast cancer consider undergoing contralateral prophylactic mastectomy.

Emerging Treatments for HER2-positive Early-stage Breast Cancer: Focus on Neratinib

Emerging Treatments for HER2-positive Early-stage Breast Cancer: Focus on Neratinib

[OncoTargets and Therapy] This research reviews available data on the role of the HER2 pathway in breast cancer and on the different targeted agents for the treatment of patients with early-stage HER2-positive disease, with a particular focus on neratinib.

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

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Use of antiperspirant or deodorant does not adversely affect potential for dermal toxicity or surface concentrations of aluminum in the axilla in women undergoing radiation therapy for breast cancer.

Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane

Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane

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A 10-year follow-up study finds disease-free survival (DFS) comparable with exemestane and sequential tamoxifen/exemestane in patients with HR-positive breast cancer.

A Review of CDK4/6 Toxicities and Interactions Management in Breast Cancer

A Review of CDK4/6 Toxicities and Interactions Management in Breast Cancer

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CDK4/6 inhibitors, which block the activity of regulatory enzymes, are tolerated fairly well in patients with cancer; however, oncology nurses should be aware of some strategies that minimize their adverse effects.

Counseling Regarding Genetic Testing in Breast Cancer Lacking, Yet Many Still Undergo BLM

Counseling Regarding Genetic Testing in Breast Cancer Lacking, Yet Many Still Undergo BLM

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Many women with breast cancer with genetic VUS undergo testing and bilateral mastectomy (BLM) without ever receiving genetic counseling.

Fat Grafting May Lead to Better Outcomes in Postmastectomy Breast Reconstruction

Fat Grafting May Lead to Better Outcomes in Postmastectomy Breast Reconstruction

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Fat grafting provides benefits to women with breast cancer considering their options for postmastectomy breast reconstruction, even though this study shows that patient-reported outcomes are similar among women who did and did not undergo the procedure.

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

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Two recent studies examined the benefits of using a 3D bioabsorbable marker to indicate the tumor bed in women with breast cancer who underwent breast conserving surgery (BCS).

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

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Risk assessment study for carriers of the BRCA1/2 mutation identified the factors that influence their risk of developing breast cancer, ovarian cancer, or contralateral breast cancer.

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

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Regular aspirin use is associated with a lower risk of breast cancer among women with diabetes, a recent study from Taiwan has shown.

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

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Breast cancer survivors who received taxane-based chemotherapy for their disease are at increased risk for falls due to CIPN and treatment-associated effects on balance and gait.

Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer

Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer

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Adding a second HER2-blocker to standard care therapy after surgery for HER2-positive breast cancer may be modestly beneficial for some women.

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Participants with high risk of depression reported lower mood disturbance, anxiety, depression following intervention.

Tai Chi Effective, Affordable Alternative to CBT-I for Insomnia in Breast Cancer Survivors

Tai Chi Effective, Affordable Alternative to CBT-I for Insomnia in Breast Cancer Survivors

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Tai chi is as effective as cognitive behavioral therapy for insomnia (CBT-I) for the treatment of insomnia in breast cancer survivors.

Even Small Amounts of Alcohol Can Affect Breast Cancer Risk

Even Small Amounts of Alcohol Can Affect Breast Cancer Risk

Even a small glass of wine each day can increase the odds of both premenopausal and postmenopausal breast cancer, evidence suggests.

Mastectomy vs BCT: Understanding Women's Treatment Choice for Early-Stage Breast Cancer

Mastectomy vs BCT: Understanding Women's Treatment Choice for Early-Stage Breast Cancer

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Canadian investigators sought to understand the factors that influence the treatment choices of women with early-stage breast cancer.

High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels

High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels

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Negative emotions were shown to motivate breast cancer survivors to engage in moderate-to-vigorous exercise, and can increase their daytime levels of cortisol.

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

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Women with triple-negative or HER2-positive breast cancer who achieve a pathologic complete response from neoadjuvant chemotherapy may be able to avoid follow-up breast or lymph node surgery.

Manipulation Increases Susceptibility of Triple-Negative Breast Cancer to Conventional Therapy

Manipulation Increases Susceptibility of Triple-Negative Breast Cancer to Conventional Therapy

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Researchers manipulated triple-negative breast cancer cells to make them susceptible to conventional antiestrogen therapy for breast cancer.

Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors

Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors

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Physical activity is proven to improve both physical and mental effects of cancer diagnosis and treatment, even if the activity needs to be modified to fit the patient's current abilities.

Mastectomy Skin Flap Necrosis: Challenges and Solutions

Mastectomy Skin Flap Necrosis: Challenges and Solutions

[Breast Cancer: Targets and Therapy] This research discusses the management options for incidents of mastectomy skin flap necrosis (MSFN).

Benefits of Radiation Therapy Undone by Smoking in Some Breast Cancer Patients

Benefits of Radiation Therapy Undone by Smoking in Some Breast Cancer Patients

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Absolute risks from radiation therapy for women with breast cancer who continue to smoke could exceed the absolute benefit of the therapy.

Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options

Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options

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Genetic signatures similar to BRCA1/BRCA2 mutations could make PARP inhibition a treatment option for some breast cancers.

Shorter Treatment of Breast Cancer with Trastuzumab May Lead to Improved Results

Shorter Treatment of Breast Cancer with Trastuzumab May Lead to Improved Results

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A significantly shorter course of trastuzumab achieved both improved outcomes for patients and cost savings for the UK National Health Service.

Antiperspirants / Deodorants and Breast Cancer (Fact Sheet)

Antiperspirants / Deodorants and Breast Cancer (Fact Sheet)

This fact sheet examines possible relationships between use of antiperspirants or deodorants and cancer risk.

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