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XOPENEX CONCENTRATE
Asthma/COPD
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Drug Name:

XOPENEX CONCENTRATE Rx

Generic Name and Formulations:
Levalbuterol (as HCl) (single-isomer albuterol) 1.25mg/0.5mL; per vial; soln for inhalation via nebulization after dilution; preservative-free.

Company:
Sunovion

Therapeutic Use:

Indications for XOPENEX CONCENTRATE:

Bronchospasm.

Adult:

Initially 0.63mg by nebulization 3 times daily at 6–8 hr intervals; may increase to 1.25mg 3 times daily.

Children:

<6yrs: not established. 6–11yrs: 0.31mg by nebulization 3 times daily; max 0.63mg 3 times daily.

Warnings/Precautions:

Do not exceed recommended dose. Monitor for increased need; if inadequate control, reevaluate and consider adding an antiinflammatory (eg, corticosteroids). Sensitivity to sympathomimetics. Discontinue if paradoxical bronchospasm or cardiovascular effects occur. Cardiovascular disorders (esp. coronary insufficiency, arrhythmias, hypertension). Seizure disorders. Diabetes. Hyperthyroidism. Renal impairment; monitor (esp. in elderly). Elderly. Labor & delivery. Pregnancy. Nursing mothers.

Interactions:

Avoid within 2 weeks of MAOIs, tricyclic antidepressants. Avoid other short-acting sympathomimetic aerosol bronchodilators, epinephrine. Antagonized by β-blockers. Caution with other drugs that may lower serum potassium (eg, diuretics). Monitor digoxin.

See Also:

XOPENEX HFA

XOPENEX

Pharmacological Class:

Beta-2 agonist.

Adverse Reactions:

Accidental injury, bronchitis, dizziness, pain, pharyngitis, rhinitis, vomiting; paradoxical bronchospasm, hypersensitivity reactions, cardiovascular effects, hypokalemia.

Generic Availability:

Vials (YES); HFA (NO)

How Supplied:

Inhaler w. actuator (80inh)—8.4g, (200 inh)—15g; Soln 0.31mg/3mL, 0.63mg/3mL, 1.25mg/3mL—24 vials; Concentrate 1.25mg/0.5mL—30 vials

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