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XODOL
Narcotic analgesics
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Drug Name:

XODOL CII

Generic Name and Formulations:
Hydrocodone bitartrate, acetaminophen; 5mg/300mg, 7.5mg/300mg, 10mg/300mg; scored tabs.

Company:
Shionogi, Inc.

Therapeutic Use:

Indications for XODOL:

Moderate to moderately severe pain.

Adult:

5mg/300mg: 1–2 tabs every 4–6 hrs as needed. 7.5mg/300mg, 10mg/300mg: 1 tab every 4–6 hrs as needed; max 6 tabs/24hrs.

Children:

Not recommended.

Warnings/Precautions:

Head injury. Increased intracranial pressure. CNS depression. Acute abdomen. Impaired renal, hepatic, thyroid, pulmonary, or adrenocortical function. GI or GU obstruction. Post-op use. Asthma. Drug abusers. Elderly. Debilitated. Pregnancy (Cat.C). Labor & delivery, nursing mothers: not recommended.

Interactions:

Potentiation with alcohol, CNS depressants (eg, narcotics, antihistamines, antipsychotics, anxiolytics), MAOIs, tricyclic antidepressants, anticholinergics (reduce dose of either or both drugs if used together).

Pharmacological Class:

Opioid + analgesic.

Adverse Reactions:

Lightheadedness, dizziness, sedation, other CNS effects, GI upset, constipation, pruritus, urinary retention, ototoxicity, CNS and respiratory depression; hepatotoxicity (overdosage).

How Supplied:

Tabs 5/300, 10/300—100, 500; 7.5/300—100

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