Women Have Clear Melanoma Survival Advantage Over Men

Share this article:
Women Have Clear Melanoma Survival Advantage Over Men
Women Have Clear Melanoma Survival Advantage Over Men

(HealthDay News) – Women with localized melanoma have a consistent advantage over men of approximately 30% for survival and progression.

Arjen Joosse, MD, from the Erasmus University Medical Center in the Netherlands, and colleagues examined the female advantage across multiple end points in four Phase III randomized adjuvant treatment trials conducted by the European Organization for Research and Treatment of Cancer Melanoma Group. A total of 2,672 patients diagnosed with stage I/II melanoma were included in the analyses.

The researchers identified a consistent and independent survival advantage for women in overall and disease-specific survival (adjusted hazard ratio [aHR], 0.70 and 0.74, respectively), and in time to lymph node and distant metastasis (aHR, 0.70 and 0.69, respectively). The survival advantage for female patients was consistent in both pre- and postmenopausal age groups and across all prognostic subgroups (except possibly for head and neck melanomas).

"Women have a consistent and independent relative advantage in all aspects of the progression of localized melanoma of approximately 30%, most likely caused by an underlying biologic sex difference," the authors write.

Abstract
Full Text (subscription or payment may be required)
Editorial

Share this article:
You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs