Use of hospital-based services, as well as hospice, increased among patients with ovarian cancer

Patients with ovarian cancer were found to be more likely to enter a hospice and less likely to die in a hospital even though their use of hospital-based services actually increased, according to a study published in the Journal of Clinical Oncology (2014; doi:10.1200/JCO.2014.55.5383).

Efforts have been widespread to improve the quality of life of terminally ill patients. As more patients choose to spend their final days and weeks in hospice care rather than a hospital, the hope is the use of intensive and costly hospital services would decline. This study by Dana-Farber Cancer Institute researchers in Boston, Massachusetts, shows that this is not happening for one group of terminally ill cancer patients.

The study, which tracked nearly 7,000 older patients with ovarian cancer, found that between 1997 and 2007, patients were more likely to enter a hospice and less likely to die in a hospital. However, their use of hospital-based services actually increased. These seemingly paradoxical findings suggest that many patients received aggressive treatments while in the hospital, and resorted to hospice care as an “add-on” when those treatments fail, the authors wrote.

“There's a growing awareness that the use of aggressive, expensive medical interventions at the end of life often doesn't improve patients' quality of life and may even make it worse,” said lead author Alexi Wright, MD, MPH, medical oncologist at Dana-Farber.

“Hospice care, which focuses on intensive symptom management at home, is an attractive option for many people. But unless people make an end-of-life care plan while they're healthy—spelling out their preferences in advance—these important decisions are often made for them, or occur in a crisis atmosphere. That may explain why, in this study, we saw an increased use of hospital-based services even as hospice enrollment increased.”

The study analyzed the Medicare records of 6,956 women age 66 years or older who received an ovarian cancer diagnosis between 1997 and 2007, and who died of the disease by the end of 2007. The researchers found that hospice use increased significantly during that period, while hospitalized deaths fell. But they also found significant increases in intensive care unit admissions, hospitalizations, repeated emergency department visits, and transitions from one health care facility to another.

During the same time frame, the proportion of patients who were referred to hospice from a hospital inpatient clinic rose. Also, 70% of patients were transferred between medical facilities at least once in the last month of life, and 20% experienced major transitions between care settings within the final 3 days of life.

The findings paint a hectic picture of elderly, terminally ill patients undergoing multiple, stressful medical interventions, undergoing transfers between facilities, all before arriving at a hospice, where their stay may be very brief.

“The earlier people can make plans with their families and physicians, the better they can control the kind of care they receive at the end of life,” Wright remarked. “Many people want their final days to be a time of legacy building, a time when they can share or build memories with their loved ones, instead of time spent in hospitals or receiving potentially futile medical interventions. Our study points to the extent to which such planning is still needed.”

Loading links....
You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs