Web Exclusives

Rabbit virus improves bone marrow transplants and kills some cancer cells

Researchers have discovered that a rabbit virus can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common and dangerous complication of bone marrow transplants.

Increasing percentages of patients undergoing breast-conserving therapy

The percentage of patients with early stage breast cancer undergoing breast-conserving therapy (BCT) increased from 54.3% in 1998 to 60.1% in 2011, according to a recent report. Notably, nonclinical factors including socioeconomic demographics, insurance, and the distance patients must travel to treatment facilities persist as key barriers to the treatment.

ALK1 protein may play a role in breast cancer metastasis

Breast cancer patients with high levels of the protein activin-like receptor kinase (ALK1) in the blood vessels of their tumors were more likely to develop metastatic disease, according to a new study. This makes inhibition of the ALK1 pathway a possible new target for the treatment of metastatic breast cancer.

Follow-up PET/CT more than 95% sensitive for non-Hodgkin lymphoma

BALTIMORE, MD—For more aggressive cases of non-Hodgkin lymphoma (NHL), posttreatment surveillance with molecular imaging could mean the early start of a new, life-saving treatment. This was presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2015 Annual Meeting.

Distinct triple-positive subtypes identified in breast cancer

CHICAGO, IL—Functional subtyping with a multigene classifier resulted in 1 in 5 tumors being reclassified compared with conventional immunohistochemistry/fluorescent in situ hybridization (IHC/FISH) analysis. This study was presented at the 2015 American Society for Clinical Oncology (ASCO) Annual Meeting.

Younger, unrelated donors with high T cell counts make better matches for patients undergoing stem cell transplant

Measuring the T lymphocyte count in stem cell transplant donors can improve matchmaking for patients in need of an allogeneic stem cell transplant.

Patients at risk for stem cell transplant complications identified

Lymphocyte recovery in related and unrelated stem cell transplant recipients generally falls into three patterns that are significantly associated with survival, according to findings from a phase 2 clinical trial.

Lifestyle intervention trial produces posttreatment weight loss in patients with breast cancer

The presence of extra body fat causes increased risk of diabetes and heart disease, and also increases the chances for breast cancer recurrence.

Chemotherapy may be the preferred option for some patients with advanced prostate cancer

In a small clinical trial, scientists found that men with advanced prostate cancer and detection of androgen receptor splice variant-7 (AR-V7) respond to chemotherapy just as well as men who lack the variant.

Scientists identify key to preventing metastatic breast cancer

Scientists identify key to preventing metastatic breast cancer

The discovery of an enzyme that facilitates the spread of breast cancer may enable clinicians to prevent secondary cancer.

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