Web Exclusives

Screening for Lynch syndrome improves health outcomes at an acceptable cost

Screening families of patients with colorectal cancer for a genetic condition would reduce their risk of developing related cancers, new research has determined.

Outcomes in nonsquamous lung cancer comparable with docetaxel or pemetrexed

The first direct comparison of treating nonsquamous lung cancer with either pemetrexed or docetaxel in addition to cisplatin has shown that the two combinations achieve similar progression-free survival.

JAK inhibitors promising in colorectal cancer

JAK inhibitors have been found to halt tumor growth in colorectal cancer with a certain genetic mutation, according to a new study.

Pertuzumab adds survival benefit for HER2-positive breast cancer

Patients with HER2-positive breast cancer that has metastasized demonstrate longer survival outcomes if treated with a combination of pertuzumab, trastuzumab, and chemotherapy.

IMPRESS trial fails to find benefit from more tyrosine kinase inhibitor (TKI) treatment after resistance develops

Patients with lung cancer that have developed resistance to the drug gefitinib experience no statistically significant improvement in progression-free survival when continued use of the drug with chemotherapy is utilized.

High-dose radiotherapy doesn't offer survival benefit in mesothelioma

Treatnent with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to phase II trial data.

Cediranib added to chemotherapy improves progression-free survival in cervical cancer

Addition of the experimental drug cediranib to standard chemotherapy improves tumor shrinkage and adds a modest improvement in progression-free survival for patients with cervical cancer that has recurred after treatment.

Anamorelin improves appetite and body mass in patients with cancer anorexia-cachexia

A new drug, anamorelin, has been found to improve appetite and body mass in patients with advanced lung cancer who are experiencing cancer anorexia and cachexia.

Afatinib improves progression-free survival in head and neck cancer

After failure of platinum-based chemotherapy, the tyrosine kinase inhibitor (TKI) afatinib significantly improved progression-free survival in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

Study confirms colonoscopy as the optimal screening measure for adenomas, colorectal cancer

For the group deemed at high risk of developing colorectal cancer, fecal blood tests appear to be a more effective means of screening than colonoscopy.

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