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Adjuvant Therapy Improves Survival in Stage II Colon Cancer, Study Confirms

A very large retrospective study of patients with stage II colon cancer found adjuvant therapy improves survival, regardless of treatment regimen, patient age, or high-risk pathologic risk features.

Hybrid Immune Cells Have Antitumor Effects in Early Stage Lung Cancer

A subset of tumor-associated neutrophils (TANs) has hybrid characteristics of both neutrophils and antigen-presenting cells in samples from early stage human lung cancers.

Clinician Communication, Adherence to Protocols, and Presence of Pharmacists Improve Outcomes in ICUs

Clinician Communication, Adherence to Protocols, and Presence of Pharmacists Improve Outcomes in ICUs

Oncologic patients are among the main users of ICUs and are vulnerable to infections and adverse drug reactions. However, relatively simple processes of organization can reduce the risk of these problems.

Identifying Smaller ctDNA Fragments Improves Sensitivity of Liquid Biopsy

Identifying Smaller ctDNA Fragments Improves Sensitivity of Liquid Biopsy

Circulating tumor DNA (ctDNA) has shorter fragment sizes than DNA fragments from healthy cells that have died, and this may increase the clinical utility of liquid biopsies.

Dual Antigen Targeting by CAR T Cells Improves Immunotherapeutic Technique

Chimeric antigen receptor (CAR) T cells may have improved therapeutic potential when they have 2 targets, according to preclinical findings using a mouse model.

Decision Support and Shared Decision Making Help Patients Choose Plan for Low-Risk Prostate Cancer

Decision Support and Shared Decision Making Help Patients Choose Plan for Low-Risk Prostate Cancer

Using an online decision-support tool led to most men with low-risk prostate cancer choosing active surveillance with less conflict about their decision.

Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors

Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors

Although most adolescent survivors of childhood cancer have no reported psychological symptoms, those who do often have multiple symptoms and distinct symptom profiles.

Advanced Endoscopy Techniques May Be Safe Alternative to Surgery for Most Difficult-to-Remove or Large Polyps

Advanced Endoscopy Techniques May Be Safe Alternative to Surgery for Most Difficult-to-Remove or Large Polyps

Most patients with large or difficult-to-remove colorectal polyps have a lower incidence of cancer than previously thought; therefore, more advanced endoscopic techniques that spare the colon may be a better and safer alternative to a traditional operation in some cases.

Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence

Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence

Genetic biomarkers from tumor DNA circulating in the bloodstream could indicate the risk for recurrence of colorectal cancer and the efficacy of chemotherapy after surgery.

Hypermutated Hotspots Are Biomarkers Predictive of Better Outcomes in Breast Cancer

Hypermutated Hotspots Are Biomarkers Predictive of Better Outcomes in Breast Cancer

Patients with kataegis, a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome, have less invasive tumors and better prognoses.

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