Web Exclusives

New mechanism of acquired resistance to breast cancer drugs discovered

Researchers have discovered that ERBB4 (also known as HER4) is a driver protein in ERBB2-positive tumors that have developed resistance to first- or second-line treatments.

Crucial role of breast cancer tumor suppressor revealed

Cells that contain lower levels of protein profilin 1 in breast tumors have an increased capacity to metastasize and invade other tissues, according to research.

What determines cost-effectiveness of targeted anticancer therapies?

What determines cost-effectiveness of targeted anticancer therapies?

An opinion published in the Journal of Thoracic Disease examines data required to determine the cost effectiveness of cancer treatments.

Physician-controlled decisions in cancer care linked to lower quality rating

Patients who reported physician-controlled decisions about their cancer care, versus shared decision-making, were less likely to report receiving excellent quality of care, according to study results.

Lung cancer may be treatable with use of SapC-DOPS technology

The therapeutic agent SapC-DOPS may have use in lung cancer treatment, according to a new study .

What autism can teach us about brain cancer

Research into the transfer of proteins within the cells of patients with autism has helped broaden our understanding of brain cancer.

New genetic anomalies linked to breast cancer in African American families

Newly discovered segments of DNA shared by African American family members who have breast cancer indicate there may still be undiscovered breast cancer genes that may be unique to African Americans.

Many patients with locally advanced breast cancer do not receive postmastectomy radiation

More than a third of women who should receive radiation subsequent to mastectomy are actually undergoing the recommended postmastectomy radiation therapy (PMRT), according to a new study.

New treatment method shrinks ovarian cancer tumors and improves chemotherapy effectiveness

A new method uses a portion of a naturally occurring protein inhibitor of angiogenesis to reduce the formation of new blood vessels required by tumors to grow.

Precise risk assessment for gastric and breast cancers among CDH1 gene mutation carriers may improve genetic counseling

More exacting estimates of age-associated risks of gastric and breast cancer were derived for carriers of the CDH1 gene mutation, a cancer-predisposing gene in families meeting criteria for clinically defined hereditary diffuse gastric cancer.

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