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VITRASERT
Ocular infections
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Drug Name:

VITRASERT Rx

Generic Name and Formulations:
Ganciclovir 4.5mg; per implant; for intravitreal implantation.

Company:
Valeant Pharmaceuticals, Inc

Therapeutic Use:

Indications for VITRASERT:

Treatment of cytomegalovirus (CMV) retinitis in patients with AIDS.

Adults and Children:

<9yrs: not recommended. ≥9yrs: Implant designed to release drug over 5–8 months. May be removed and replaced following depletion of ganciclovir.

Contraindications:

External infection. Severe thrombocytopenia.

Warnings/Precautions:

Should be administered by surgeon who has observed or assisted in surgical implantation of Vitrasert prior to attempting procedure. Monitor for extraocular CMV disease. Ophthalmologic follow-up advised at appropriate intervals. Pregnancy (Cat.C). Nursing mothers: not recommended.

Pharmacological Class:

Nucleoside analogue.

Adverse Reactions:

Visual acuity loss of 3 lines or more, vitreous hemorrhage, retinal detachments, cataract formation/lens opacities, macular abnormalities, intraocular pressure spikes, optic disk/nerve changes, hyphemas, uveitis.

How Supplied:

Implant—1

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