ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

TYVASO
Pulmonary hypertension
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

TYVASO Rx

Generic Name and Formulations:
Treprostinil 0.6mg/mL; soln for oral inhalation using Tyvaso Inhalation System.

Company:
United Therapeutics Corp.

Therapeutic Use:

Indications for TYVASO:

Pulmonary arterial hypertension (WHO Group I) in patients with NYHA Class III symptoms, to improve exercise ability.

Adult:

Give 4 separate treatment sessions each day approximately 4hrs apart, during waking hours. ≥18yrs: Initially 3 breaths (18mcg) per treatment session; if not tolerated, reduce to 1–2 breaths, and then subsequently increase to 3 breaths as tolerated. Maintenance: may increase by an additional 3 breaths at 1–2 week intervals, if tolerated, to target dose of 9 breaths (54mcg) per treatment session.

Children:

<18yrs: not established.

Warnings/Precautions:

Significant underlying lung disease (eg, asthma, COPD). Acute pulmonary infections. Patients with low systemic arterial pressure. Hepatic or renal insufficiency. Risk of bleeding. Avoid contact with eyes and skin, oral ingestion. Elderly. Labor & delivery. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Increased risk of symptomatic hypotension with concomitant diuretics, antihypertensives, other vasodilators. May be potentiated by CYP2C8 inhibitor (eg, gemfibrozil). May be antagonized by CYP2C8 inducer (eg, rifampin). Increased risk of bleeding with anticoagulants.

Pharmacological Class:

Prostacyclin analogue.

Adverse Reactions:

Cough, headache, nausea, diarrhea, dizziness, flushing, throat irritation, pharyngolaryngeal pain, syncope; symptomatic hypotension, bleeding.

Generic Availability:

NO

How Supplied:

Ampules (2.9mL)—4; Starter Kit—1 (28 ampules with inhalation system); Refill Kit—1 (28 ampules with accessories)

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs