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Tetracycline
Acne
Bacterial infections
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Drug Name:

Tetracycline Rx

Generic Name and Formulations:
Tetracycline HCl 250mg, 500mg; caps.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Tetracycline:

Adjunct in severe acne.

Adult:

Take with fluids, 1 hour before or 2 hours after meals. Initially 1g daily in 2–4 divided doses. After improvement: 125–500mg daily.

Children:

Not recommended.

Warnings/Precautions:

Renal impairment. Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Discontinue if skin erythema occurs. Pregnancy (Cat.D), nursing mothers: not recommended.

Interactions:

Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics; avoid. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Pharmacological Class:

Tetracycline antibiotic.

Adverse Reactions:

Photosensitivity, GI upset, rash, blood dyscrasias, increased BUN, hepatotoxicity; rare: esophagitis and esophageal ulceration.

Note:

Formerly known under the brand names Achromycin V, Tetracyn, Tetrex.

How Supplied:

Contact supplier.

Indications for Tetracycline:

Tetracycline-sensitive infections, including respiratory, genitourinary, skin and soft tissue, and those caused by rickettsiae and Mycoplasma pneumoniae; also cholera, psittacosis, plague, shigellosis.

Adult:

Take with fluids, 1 hour before or 2 hours after meals. 250–500mg 4 times daily.

Children:

<8yrs: not recommended. Take with fluids, 1 hour before or 2 hours after meals. ≥8yrs: 25–50mg/kg/day in 4 divided doses.

Warnings/Precautions:

Renal impairment. Monitor blood, renal and hepatic function in long-term use. Avoid sun and UV light. Discontinue if skin erythema occurs. Pregnancy (Cat.D), nursing mothers: not recommended.

Interactions:

Avoid methoxyflurane, photosensitizing agents. May antagonize bactericidal antibiotics; avoid. Reduced absorption with antacids, iron, zinc, calcium, magnesium, dairy products, urinary alkalinizers, other multivalent cations. May reduce effectiveness of oral contraceptives. Monitor prothrombin time with oral anticoagulants.

Pharmacological Class:

Tetracycline antibiotic.

Adverse Reactions:

Photosensitivity, GI upset, rash, blood dyscrasias, increased BUN, hepatotoxicity; rare: esophagitis and esophageal ulceration.

Note:

Formerly known under the brand names Achromycin V, Tetracyn, Tetrex.

How Supplied:

Contact supplier.

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