T-cells

Mimicking Fasting During Chemotherapy Enhances T Cell Activity in Preclinical Study

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Fasting during chemotherapy treatment may increase the presence of cancer-killing T cells, according to recent study data.

Markers Found on Solid Tumors Are a Target for CAR T Cell Therapy

Markers Found on Solid Tumors Are a Target for CAR T Cell Therapy

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Chimeric antigen receptor (CAR) T cell therapy is now moving toward effectiveness against solid tumors, based on recent work in mouse models. CAR T cell therapy has already had successes against aggressive blood cancers.

TRAIL stops graft-vs-host disease after stem cell transplant for leukemia

T cells overexpressing the TRAIL protein destroyed graft-versus-host disease caused by stem cell transplant for leukemia and other cancers.

Reprogrammed donor cells thwart leukemia relapse

Specially treated T cells infused into high-risk and relapsed leukemia patients can prolong survival after stem cell transplantation.

Cancer vaccines self-sabotage by channeling immune attack to injection site

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In vaccines that stimulate an immune system assult, T cells aimed at tumors instead find the vaccination site a more inviting target.

T-ALL leukemia found to differ between adults and children

T-cell acute lymphoblastic leukemia (T-ALL) in adults has significantly more mutations than does T-ALL in children, scientists have discovered.

Nelarabine plus chemo viable in children with T-cell ALL

Nelarabine plus chemo viable in children with T-cell ALL

Nelarabine is well tolerated and encouraging for pediatric patients with a slow early response in T-cell ALL.

Diagnosis of non-Hodgkin's lymphoma

The non-Hodgkin's lymphomas (NHLs) are a heterogeneous group of tumours of the lymphoid system and a relatively complex group of disorders. Presentation can be variable with many patients developing extranodal disease. The disease accounts for 4% of all cancer in the UK.

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