E-cigarettes have a strong potential to improve population health by reducing or displacing cigarette use. A team of international experts urged the US FDA to have a broad perspective when it comes to regulating e-cigarettes.
An AYA patient survivorship program jointly designed by a cancer institute and a community organization educates patients about their oncologic history and the effects of therapy, as well as provides resources to improve quality of life.
Socioeconomic status and features of physical health rather than tumor characteristics were associated with symptoms of depression among long-term survivors of colorectal cancer.
Longer survival was achieved with stereotactic radiosurgery (SRS) alone than with whole-brain radiation therapy (WBRT) in patients with fewer than 4 brain metastases from NSCLC or breast cancer.
The addition of chemotherapy to radiation therapy prolonged survival in adults with grade 2 glial brain tumors.
Continuation of ceritinib therapy beyond disease progression was associated with prolonged survival, according to results from a retrospective study of the use of ceritinib to treat advanced ALK-positive NSCLC.
Smokers who visit a clinician for lung cancer screening should also be encouraged to quit smoking at that visit. Evidence-based behavioral strategies should be used, at each visit, to motivate smokers to quit.
Researchers found that men with prostate cancer who had exercised regularly had the best outcomes.
A study examined the relation between various forms of breast cancer therapies and risk of congestive heart failure.
Two new compounds suppress tumor growth in cell culture and mouse xenograft models of Ewing sarcoma, a rare pediatric cancer. These 2 compounds are similar to mithramycin, also known as picamycin, a drug no longer manufactured due to its toxicity.
Older women with diabetes and cancer taking metformin saw an increase in survival.
New technology has enabled doctors to administer higher doses of radiation to prostate cancer tumors with fewer side effects; however, escalating the dose of radiation may not help patients with localized prostate cancer in the long term.
Patients with classical Hodgkin lymphoma who are resistant to the CD30-directed antibody-drug conjugate brentuximab vedotin have poor outcomes.
Site of metastasis is key to the length of time a patient can survive metastatic castration-resistant prostate cancer (mCRPC).
Higher Treatment Volumes at Radiation Facilities Lead to Improved Overall Survival in Prostate Cancer
Among men with aggressive prostate cancer, overall survival (OS) rates improve when they receive radiation treatment at facilities that frequently perform the treatment.
Anxiety and Depressive Symptoms Are Increased in Pediatric Survivors of Acute Lymphoblastic Leukemia
Emotional distress during and after undergoing chemotherapy for ALL affects a significant percentage of children with the disease.
Prolonged nightly fasting may reduce the risk of recurrence for patients with breast cancer.
The Samfund is a not-for-profit organization dedicated to easing the lasting financial effects of cancer treatments for young adults with the disease.
A complex surgical procedure to remove the prostate achieves excellent long-term survival for men with prostate cancer after radiation therapy has failed.
A weekly dose of temsirolimus 75 mg was found to be active in patients with relapsed/refractory primary CNS lymphoma (PCNSL); however, only some patients achieved long-term control.
Among women aged up to 49 years with a pregnancy-associated melanoma, recurrence rates were higher than seen in other groups.
Patients who have had cancer recently can still be treated with antibodies against tumor necrosis factor for inflammatory bowel disease.
Study Findings Show Possible Association Between PreLabor Cesarean Delivery and Risk for ALL in Young Children
The finding that prelabor cesarean delivery may have a correlation with acute lymphoblastic leukemia (ALL) may offer new targets for research into preventing cancer.
Model Demonstrates Benefits of MRI Screening for Breast Cancer in Survivors of Childhood Hodgkin Lymphoma
Female survivors of childhood Hodgkin lymphoma (HL) who received chest radiation can reduce their risk of breast cancer through early screening.
High neutrophil to lymphocyte ratio (NLR) is linked to worse prognosis in Caucasian patients with early breast cancer.
Reliance on PET to Detect Lung or Esophageal Cancer Recurrence May Lead to Overuse of the Imaging Modality
In posttreatment follow-up of lung and esophageal cancer, PET scans might be overused to detect cancer recurrence. Furthermore, PET scan use to detect recurrence does not increase survival.
Chemotherapy agents commonly used to treat childhood cancer impair eyesight in a way that indicates an impact on the CNS. The damage occurs to the patient's eye motor skills.
Immense financial challenges confront young adults with cancer. As a result of medical bills and the loss of savings, these patients may forgo recommended medications and/or follow-up appointments.
Survival rates are not increased and the likelihood of receiving a full course of radiation is decreased for patients with locally advanced head and neck cancer who receive IC rather than the standard treatment of CRT.
Unmet health information needs, even nearly a decade after a cancer diagnosis, were a key finding of a study of the needs of cancer survivors who are at least 9 years beyond an initial diagnosis.
As the American College of Surgeons' Commision on Cancer milestones approach, ASTRO publishes a template to ensure consistent, comprehensive survivorship care plans can be developed for cancer survivors whose treatment involved radiotherapy.
Researchers have noted a link between supportive care and reduced risk of adverse outcomes.
Posttreatment imaging at 3 months and physical examinations during the 6 months following treatment can detect most recurrences in patients treated with definitive radiation therapy for HPV-associated oropharyngeal cancer.
Paclitaxel administered with carboplatin on a weekly basis is not associated with improved progression-free survival.
Pediatric survivors of ALL treated only with chemotherapy remain at an increased risk for attention problems 2 years after treatment cessation.
A group of pediatric oncology psychosocial experts developed evidence-based standards for the care of children with cancer and their families.
A significant decrease in muscle area was seen in patients with metastatic colorectal cancer (mCRC) receiving chemotherapy, which was independently associated with survival in these patients.
Depressive Symptoms Linked to Worse Survival Following Hyperthermic Intraperitoneal Chemotherapy With Cytoreductive Surgery
A study examined the relationship between depression and survival for patients undergoing hyperthermic intraperitoneal chemotherapy combined with cytoreductive surgery.
The intensity of end-of-life care for patients with myelodysplastic syndromes may be optimal in terms of hospice use, a recently published study has shown.
An exercise intervention did not improve physical functioning for women living with advanced breast cancer, according to a study.
Osteosarcoma in children may be impacted by a defect in DNA imprinting that also occurs in their biological parents. These imprinting defects may be predictive of survival outcomes.
Most patients with resected non-small cell lung cancer (NSCLC) preferred a collaborative role in decision-making about adjuvant chemotherapy.
Hematopoietic cell transplantation (HCT)-related concerns at the time of hospital discharge predict increases in depression but not in anxiety.
After experiencing the benefits of meditation to help himself cope with the stress of caring for patients with cancer, this oncologist leads classes teaching those patients to use the tool to better cope with their disease and its effects.
Patients with cancer, including those with a tobacco-related cancer, do not seem to be more likely to quit smoking than the general population.
Men with prostate cancer and bone metastases that have experienced at least one skeletal-related event (SRE) show worse survival, according to a recent study.
Smokers have good reason to quit the habit both before and after a breast cancer diagnosis.
[OncoTargets and Therapy] Anaplastic large cell lymphoma (ALCL) frequently involves the bone marrow, but primary or secondary involvement to the bone is rare. This article examines a case of anaplastic lymphoma kinase positive ALCL with prominent bone involvement in a young boy.
African-American pediatric patients with Hodgkin lymphoma still display a considerable survival disparity when compared to their white and Hispanic peers.
Treating medulloblastoma with proton beam therapy results in survival rates in line with other proton therapies, according to recent study data.
A recent study examined factors that impact patient preferences for web- and phone-based tobacco cessation programs.
Intensive care unit survivors have higher mortality, use of hospital resources in five years after discharge.
Early cardiovascular events are a risk for survivors of childhood cancer, according to researchers who also advocate for a unified definition of pediatric metabolic syndrome.
No increase in locoregional recurrence, systemic recurrence, or second breast cancer observed following breast lipofilling procedure.
Use of minimally invasive hysterectomy is linked to favorable morbidity profile and does not compromise long-term survival for patients.
Ob-gyns report external examinations are important for cancer detection and lesion identification.
Phase 2 trial data showed acceptable toxicity and similar survival as conventional radiotherapy for childhood medulloblastoma.
US cancer survivors are not more likely than the general population to engage in all healthy lifestyle behaviors.
Chemotherapy, with or without cranial irradiation, has been associated with improved survival versus surgery alone for patients with early-stage small-cell lung cancer (SCLC) undergoing resection.
Initiating a palliative care consultation in the ED improved quality of life and survival was not shortened in patients with advanced cancer.
A simple blood test can identify post-chemo patients with the NPM1 gene mutation.
Valproic acid and levetiracetam do not improve survival outcomes in patients with newly diagnosed glioblastoma, according to a recently published study.
No significant difference in survival was observed with VTE, but odds of esophageal cancer ecurrence are increased.
Survivorship care plans led to improved outcomes in a randomized, controlled trial reported at the American Society of Clinical Oncology 2016 Cancer Survivorship Symposium.
Adolescent and Young-adult Survivors of Hodgkin Lymphoma May Not Adhere to Follow-up Recommendations
Within the first year posttreatment, more than half of Hodgkin lymphoma survivors did not receive all recommended care. However, 96% had their recommended oncology visits and 70% had the recommended laboratory tests within the first 5 years.
Mortality rate changes in the United States since 1991 translate to an additional 1.7 million cancer survivors.
Lifelong screening is recommended for survivors of childhood cancer that affects the vision, in order to detect issues early.
A study compared the effectiveness of volasertib versus chemotherapy for treatment of platinum-resistant or -refractory ovarian cancer.
Cancer-induced Weakness in Immune System May Be Key to HER2+ Breast Cancer Recurrence, and Prevention
T cells from patients whose breast cancer had recently recurred showed weak response to the HER2 receptor protein, according to a recent study. The study findings suggest that immune status monitoring may be used to gauge the risk of recurrence.
New Studies Reveal Long-Term Vision-related Health Concerns of Survivors of Childhood Retinoblastoma and Brain Cancer
Two new studies investigate the impact of retinoblastoma on long-term health of survivors and the long-term psychological and socio-economic effects of blindness in survivors of brain tumors.
Improved survival for patients treated by higher-volume radiation oncologists was observed.
Exposure to anthracycline and heart radiation has been tied to higher odds of cardiac disease.
Health-related quality of life (HRQOL) is significantly better for cancer survivors than for persons with chronic diseases without cancer, based on questionnaire responses reported in a study.
Adolescents and young adults (AYAs) with hematologic malignancies experience significant psychological morbidities during treatment and early survivorship.
Medicaid benefits are an important part of the health care landscape for low-income cancer survivors.
Rates of 6-month continuous abstinence after lung cancer screening did not differ between black smokers and white smokers despite a higher likelihood of 24-hour and 7-day quit attempts by black smokers.
Improvements to progression-free survival (PFS) seen across patient subgroups treated with cabozantinib.
Researchers observed significant changes in health-related quality of life (HRQoL), depression, and sexual function among patients with breast cancer receiving chemotherapy.
Docetaxel should be added at initiation of standard of care treatment in men with prostate cancer; however, no evidence of survival improvement was seen with zoledronic acid therefore it is not recommended as part of standard of care for this patient population.
A recent study examined the efficacy of pembrolizumab for the treatment of previously treated, PD-L1-positive, advanced non-small-cell lung cancer.
Survivors of thyroid cancer report their quality of life after diagnosis and treatment as poor compared with patients whose diagnoses are more lethal cancers.
Tumor Location and Duration of Therapy Influence Palliative Effects of Radiation Therapy for Painful Bone Metastases
In a review of the Dutch Bone Metastasis Study results, stratified for primary tumor location, palliative radiation therapy was found to reduce pain and improve quality of life for some patients.
The longest survival time was observed for primary debulking surgery coupled with chemotherapy in an optimal timeframe.
Depression is a significant predictor of 5-year survival and recurrence in patients with head and neck cancer. These findings represent one of the largest studies to report on the impact of depression on cancer survival.
Mindfulness-based Stress Reduction Reduces Cognitive Deficits in Survivors of Breast and Colorectal Cancers
Participation in an MBSR program yields robust and sustained improvement in cancer-related cognitive impairment.
American Cancer Society and American Society of Clinical Oncology publish their breast cancer survivorship care guideline, providing care guidance for the estimated 3.1 million female adult survivors of breast cancer in the United States.
Association Is Found Between Bone Complications in Young Pediatric Patients With Leukemia and Gene Variations
Variations in genes involved in normal bone development are associated with an 8- to 15-fold increased risk for osteonecrosis in young patients with acute lymphoblastic leukemia (ALL).
Radiotherapy is the most effective single modality for local control of Hodgkin lymphoma. Involved site radiotherapy is a recent innovation intended to reduce the risk of late effects—an urgent goal, particularly for adolescent and young adult patients.
Risk of death from all causes is 45% higher in women with breast cancer and a subsequent diagnosis of depression, according to a recent study. This finding could help identify those women most at risk for depression and in need of support.
Understanding the effect of cancer on health-related quality of life is vital for optimal patient care.
Ten-year Overall Survival Is Higher After Breast-conserving Therapy Compared With Mastectomy in Early Stage Breast Cancer
Breast-conserving surgery with radiation therapy (BCT) demonstrated improved 10-year overall survival in patients with early stage breast cancer compared with mastectomy without radiation therapy, according to data presented at the 2015 San Antonio Breast Cancer Symposium.
There are benefits for breast and colorectal cancer survivors with mindfulness-based stress reduction, study data indicates.
Women who were taught how to manage stress early in their breast cancer treatment showed greater length of survival and longer time until disease recurrence over 8 to 15 years after their original diagnosis.
Nipple-sparing Mastectomy Offers Better Cosmetic and Psychological Outcomes for Patients With Breast Cancer
Nipple-sparing mastectomy and immediate breast reconstruction results in higher reported patient body image, when compared to skin-sparing partial mastectomy (SS-PM), and may lower risk of local recurrence.
Results of a phase 3 randomized trial support high intensity conditioning with myeloablative regimens prior to allogeneic stem cell transplantation as standard of care for patients with acute myeloid leukemia.
Immunophenotypic expression profiles can provide a tool to discriminate cohorts of young patients with acute myeloid leukemia (AML) that have a high relapse probability.
For patients with chronic phase chronic myeloid leukemia (CP-CML) and the T315I mutation, ponatinib treatment may offer longer overall survival.
Although a fourth chemotherapy course may benefit younger patients with poor-risk acute myeloid leukemia, those with good and standard risk demonstrated little survival benefit from the additional course.
Continuous antibiotic treatment can reduce infections in young patients with acute lymphoblastic leukemia (ALL).
Addition of Midostaurin Significantly Improved Event-Free and Overall Survival in Some Patients With Acute Myeloid Leukemia
The addition of midostaurin, a multi-target protein kinase inhibitor, to to standard chemotherapy for AML has been associated with increased survival.
- Phase 1 Study Results Show CAR T-cell Therapy Promising in Solid Brain Tumors
- Initiating Palliative Care in the Emergency Department
- A Review of Systemic Treatment in Metastatic Triple-Negative Breast Cancer
- Follow-up Calls, Clinician Assessment May Identify Patients Who Need Adherence Support
- Precision Medicine Resource Center Improves Patient Education
- Sugar and Cancer: Mitigating the Affects of Diet on Cancer
- Nurse Residency Programs Can Impact Oncology Nursing Practice, Outcomes
- Acupuncture Improves Management of Hot Flashes, Quality of Life in Breast Cancer
- Higher Vitamin D Levels Lower Risk of Cancer in Women
- Getting Started: Implementation of an Oncology Navigation Program That Meets Community Needs
- Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts
- Proactive management strategies for potential gastrointestinal adverse reactions with ceritinib in patients with advanced ALK-positive non-small-cell lung cancer
- Disparities in Gut Microbiome Could Lead to Biomarkers for Estrogen-driven Breast Cancer
- SPF30 Sunscreens Delay Melanoma in Preclinical Model
- New Drug Combination Before Surgery May Improve Outcomes for Advanced HER2+ Breast Cancer
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