Risk for Adverse Pulmonary Events Higher in Adult Survivors of Childhood Cancer

Risk for Adverse Pulmonary Events Higher in Adult Survivors of Childhood Cancer

Adult survivors of childhood cancer are at increased risk for late adverse pulmonary events.

Study Identifies Disparities in Cancer Pain Management

Study Identifies Disparities in Cancer Pain Management

Cancer survivors who are nonwhite, less educated, older, and/or have comorbidities were less likely to receive adequate cancer pain management.

Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma

Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma

[OncoTargets and Therapy] This research reviews the effects of single-port access transaxillary totally endoscopic thyroidectomy on outcomes following surgery, including quality of life and cosmetic result, in patients with papillary thyroid carcinoma (PTC).

Sexual Dissatisfaction Prevalent Among Cancer Survivors, Especially in Women

Sexual Dissatisfaction Prevalent Among Cancer Survivors, Especially in Women

Older cancer survivors' self-reports of sexual activity and functioning are comparable to age-matched people without cancer; despite this, sexual dissatisfaction is more prevalent among cancer survivors than age-matched cancer-free persons.

Addition of Elotuzumab to Bortezomib/Dexamethasone Improves Survival in Relapsed/Refractory Multiple Myeloma

Addition of Elotuzumab to Bortezomib/Dexamethasone Improves Survival in Relapsed/Refractory Multiple Myeloma

The addition of elotuzumab to bortezomib/dexamethasone appears to increase progression-free survival in relapsed/refractory multiple myeloma (RRMM).

Survivors Diagnosed at Young Age More Likely to be Financially Dependent

Survivors Diagnosed at Young Age More Likely to be Financially Dependent

Younger cancer survivors in Norway were more likely to be financially dependent and unemployed than individuals without cancer.

In NSCLC, Erlotinib Appears Effective at Doses Lower Than MTD

In NSCLC, Erlotinib Appears Effective at Doses Lower Than MTD

Patients with metastatic non-small cell lung cancer demonstrated prolonged median progression-free survival with the administration of erlotinib below the maximum tolerated dose.

Metformin Use May Improve Survival in Patients With CRC, Diabetes

Research indicates that metformin can confer improved survival for patients with colorectal cancer that also have diabetes.

Adding Daratumumab to Lenalidomide/Dexamethasone Improves Survival in Multiple Myeloma

Adding Daratumumab to Lenalidomide/Dexamethasone Improves Survival in Multiple Myeloma

Treatment with daratumumab, lenalidomide, and dexamethasone (DRd) may be superior to lenalidomide and dexamethasone (Rd) alone in patients with relapsed or refractory multiple myeloma.

CML-CP: Dasatinib, Nilotinib Associated With Similar Survival Outcomes as Frontline Therapy

Dasatinib and nilotinib are associated with similar response rates and survival outcomes in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP).

Medicaid Insurance Linked to Worse Outcomes for Patients With Glioblastoma Multiforme

Medicaid Insurance Linked to Worse Outcomes for Patients With Glioblastoma Multiforme

Insurance status influences overall patient survival for some cancer types, but its impact on glioblastoma multiforme (GBM) survival is well documented. This research study explored the possible impact of insurance on GBM survival.

ADT May Reduce Survival in African American Men With Favorable-risk Prostate Cancer

ADT May Reduce Survival in African American Men With Favorable-risk Prostate Cancer

Use of androgen suppression therapy may negatively impact survival in African American patients with favorable-risk prostate cancer.

Age-Related Prognosis in Breast Cancer Varies by Subtype

Age-Related Prognosis in Breast Cancer Varies by Subtype

Survival among women age 40 years and younger with breast cancer appears to vary according to breast cancer subtype, with age particularly prognostic for women with luminal type breast cancers.

Medicaid Insurance Linked to Worse Head and Neck Cancer Outcomes

Medicaid Insurance Linked to Worse Head and Neck Cancer Outcomes

A recent study examined the possible correlation between Medicaid coverage status and overall survival for patients with head and neck cancer.

Salvage Radiotherapy at Lower PSA Levels May be Beneficial

Salvage Radiotherapy at Lower PSA Levels May be Beneficial

As salvage radiotherapy (SRT) outcomes may be affected by factors associated with prostatectomy findings, they may be positively affected when used at lower prostate-specific antigen (PSA) levels.

Acupressure Improves Fatigue, Sleep, and Quality of Life for Survivors of Breast Cancer

Acupressure Improves Fatigue, Sleep, and Quality of Life for Survivors of Breast Cancer

Acupressure reduced persistent fatigue in women who had been treated for breast cancer, improving both sleep and quality of life.

Quality of Life Not Affected by Active Surveillance of Prostate Cancer

Quality of Life Not Affected by Active Surveillance of Prostate Cancer

Choosing no treatment and regular check-ups didn't seem to stress men with low-risk disease

Fitness Nearly as Important as Not Smoking for Longevity

Fitness Nearly as Important as Not Smoking for Longevity

Low aerobic capacity has greater effect on longevity than even high cholesterol, or high blood pressure.

Tyrosine Kinase Inhibitor Therapy Can Be Safely Stopped in Select Patients With CML in Chronic Phase

Tyrosine Kinase Inhibitor Therapy Can Be Safely Stopped in Select Patients With CML in Chronic Phase

A high percentage of patients with CML treated with TKIs achieve deep molecular responses and can safely stop therapy. Initials results of the EURO-SKI trial define prognostic markers that indicate durability of deep molecular responses after stopping TKI therapy.

Systematic Palliative Care Provides Greater Improvement in Quality of Life for Patients with Pancreatic Cancer

Systematic Palliative Care Provides Greater Improvement in Quality of Life for Patients with Pancreatic Cancer

Quality of life is significantly improved for patients with pancreatic cancer when systematic palliative care is administered vs on-demand palliative care.

Adjuvant Therapy Improves Survival in Stage II Colon Cancer, Study Confirms

A very large retrospective study of patients with stage II colon cancer found adjuvant therapy improves survival, regardless of treatment regimen, patient age, or high-risk pathologic risk features.

Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors

Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors

Although most adolescent survivors of childhood cancer have no reported psychological symptoms, those who do often have multiple symptoms and distinct symptom profiles.

Telomere Length Predicts Risk for Delayed Recovery in Pediatric Patients With AML

Telomere Length Predicts Risk for Delayed Recovery in Pediatric Patients With AML

Telomere length is predictive for determining which children treated for AML are at highest risk for delayed recovery, a finding that may have significant implications for treatment-related morbidity and mortality.

Increasing Numbers of Older Cancer Survivors Challenge Clinical Trial Participant Criteria

Improved cancer detection and advances in treatment mean larger numbers of older cancer patients are becoming survivors, combined with demographic trends. But older patients are underrepresented in clinical trials.

Nivolumab Maintains Baseline HRQoL in Advanced Melanoma

Nivolumab Maintains Baseline HRQoL in Advanced Melanoma

In addition to improving overall survival compared with dacarbazine in patients with advanced melanoma, nivolumab maintains baseline levels of health-related quality of life to ultimately confer long-term quality of survival benefit.

Unrealistic Patient Expectations Top Barrier to Quality EOL Care

Unrealistic Patient Expectations Top Barrier to Quality EOL Care

In a large cohort of hematologic oncologists surveyed in the United States, standard end-of-life quality measures were highly acceptable, but unrealistic patient expectations are the greatest impediment to quality end-of-life care.

Moderate-to-Vigorous Exercise Improves Subjective Memory in Breast Cancer Survivors

Moderate-to-Vigorous Exercise Improves Subjective Memory in Breast Cancer Survivors

Memory problems in breast cancer survivors appear associated with the high stress load these patients experience rather than their treatment, and moderate-to-vigorous physical activity may help subjective memory in these patients.

Nonsolid Nodules Unlikely to Cause Death in Lung Cancer

Nonsolid Nodules Unlikely to Cause Death in Lung Cancer

Lung cancers that manifest as nonsolid nodules seem to have indolent course, according to recent research data.

Among Survivors, Relaxing Acupressure Improves Fatigue, Sleep Quality, QoL

Among Survivors, Relaxing Acupressure Improves Fatigue, Sleep Quality, QoL

Relaxing acupressure resulted in significant improvement in persistent fatigue, sleep quality, and quality of life among survivors of breast cancer, a recent study has shown.

POSTCARE Intervention May Improve QoL Among Cancer Survivors

POSTCARE Intervention May Improve QoL Among Cancer Survivors

The Patient-Owned Survivorship Transition Care for Activated, Empowered survivors (POSTCARE) intervention resulted in clinically meaningful improvements in 3 domains of quality of life (QoL) among survivors of breast cancers.

Surgery and Adjuvant Hormonal Therapy Less Effective for Older Patients With Breast Cancer

Surgery and Adjuvant Hormonal Therapy Less Effective for Older Patients With Breast Cancer

A group of researchers sought to examine the physical functioning of patients with breast cancer, in various age brackets, who were enrolled in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) phase III trial.

U.S. Cancer Survivors Aging, Battling Other Chronic Conditions

U.S. Cancer Survivors Aging, Battling Other Chronic Conditions

Likelihood of other chronic conditions will stress health care system in next two decades, as more patients with cancer live longer.

Nearly 1 in 12 Patients With a Common Cancer Develops a Second Cancer

Nearly 1 in 12 Patients With a Common Cancer Develops a Second Cancer

Nearly 1 in 12 patients with a cancer from the 10 most common cancer sites developed a second primary neoplasm during survivorship.

Many Older Women With Early Stage Breast Cancer Are Susceptible to Functional Decline After Starting Treatment

Approximately 20% of older women with stage I-III breast cancer lost the ability to complete some basic tasks of independent living within 1 year of starting treatment. However, an assessment tool can identify those women at greatest risk of posttreatment functional decline.

Extent of Resection Influences Length of Progression-Free Survival in Glioblastoma

Extent of Resection Influences Length of Progression-Free Survival in Glioblastoma

Gross total resection to treat glioblastoma multiforme (GBM) showed progression-free survival benefits over subtotal resection and biopsy in a meta-analysis of 37 studies.

Autologous Stem Cell Transplant Safe as Standard of Care in Patients With HIV-Associated Lymphoma

Autologous Stem Cell Transplant Safe as Standard of Care in Patients With HIV-Associated Lymphoma

Recent results from a multicenter, phase 2 trial suggest that patients with HIV and aggressive lymphoma should receive autologous stem cell transplant as standard of care. Risk of serious complications after transplant in these patients is equal to that of patients without HIV.

Surgery Improves Quality of Life for Patients With Malignant Pleural Mesothelioma

Surgery Improves Quality of Life for Patients With Malignant Pleural Mesothelioma

Undergoing pleurectomy and decortication for malignant pleural mesothelioma generally leads to improved quality of life after the surgery.

Type of End-of-Life Care Received Varies Based on Type of Disease

Type of End-of-Life Care Received Varies Based on Type of Disease

Cancer and dementia patients get more access to palliative care than do patients with many other chronic conditions, recent research indicates.

Overall Survival and Progression-Free Survival Are Improved With Ibrutinib for del17p CLL

Overall Survival and Progression-Free Survival Are Improved With Ibrutinib for del17p CLL

Ibrutinib treatment for chronic lymphocytic leukemia with the deletion of chromosome 17p (del17p CLL) increases the percentage of patients alive at 30 months over other therapies for del17p CLL.

Novel Antibody-Drug Conjugate Bridges Patients With Relapsed ALL to Stem Cell Transplant

Novel Antibody-Drug Conjugate Bridges Patients With Relapsed ALL to Stem Cell Transplant

In a randomized phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with ALL whose disease had relapsed following standard therapies, qualified for stem cell transplants after treatment with the drug.

Intensive Protocol Improves Survival for Adults with Acute Lymphoblastic Leukemia

Intensive Protocol Improves Survival for Adults with Acute Lymphoblastic Leukemia

Event-free survival for adult patients with ALL has improved from 40% to 73% with the implementation of the NOPHO ALL 2008 protocol in July 2008.

Adjuvant Chemotherapy Improves Overall Survival in Early Stage NSCLC

Adjuvant chemotherapy in patients with stage Ib non-small cell lung cancer improved overall survival and 5-year overall survival.

Number of Ovarian Cancer Cases Not Treated Surgically or Not Treated at All Is Increasing

Number of Ovarian Cancer Cases Not Treated Surgically or Not Treated at All Is Increasing

The number of patients older than 75 years who do not undergo surgery is increasing, especially among those with stage III or IV ovarian cancer. Approximately 50% do not undergo surgery and 25% receive no treatment at all.

New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases

New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases

Researchers demonstrate how breast cancer cells invade bone marrow, where they escape chemotherapy and hormonal therapies that would otherwise eliminate the cancer cells.

Metastatic Ability May Precede Tumor Formation in Pancreatic Cancer

Metastatic Ability May Precede Tumor Formation in Pancreatic Cancer

Metastatic capabilities of pancreatic cancer might arise before tumors even form. Metastasis and advanced stage of disease at diagnosis are attributed to low survival rates for pancreatic cancer.

Carfilzomib Increases Survival for Patients With Relapsed Multiple Myeloma

Carfilzomib Increases Survival for Patients With Relapsed Multiple Myeloma

A post-hoc analysis of the Phase 3 ASPIRE study indicates that treatment combining carfilzomib with lenalidomide and dexamethasone extended survival time for patients with multiple myeloma.

Biochemical Marker Is a Better Predictor of Adverse Effects in Patients with Non-small Cell Lung Cancer

Albumin concentration with an established cutoff point is proven a better predictor of both chemotherapy toxicity and survival in patients with advanced lung cancer.

CDC: Cigarette Smoking Drops in U.S. Adolescents

CDC: Cigarette Smoking Drops in U.S. Adolescents

A decreasing number of adolescents are smoking, but e-cigarette use and rates of distracted driving are on the rise for this group.

ASCO: Smartphone App May Help Lung Cancer Patients Live Longer

ASCO: Smartphone App May Help Lung Cancer Patients Live Longer

Researchers found tracking symptoms and alerting doctors to problems early led to longer survival for patients with lung cancer.

Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication

Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication

Physical exercise may have a direct effect on cancer that is as effective as drugs for treating patients with prostate cancer, even for those with advanced stages of the disease.

ASCO: Aggressive Treatment Common in Terminal Cancer Patients

ASCO: Aggressive Treatment Common in Terminal Cancer Patients

Three in four of young or middle-aged patients with terminal cancer receive aggressive therapies in their last months of life.

Pembrolizumab Demonstrates Long-Term Survival in Advanced Melanoma

Pembrolizumab Demonstrates Long-Term Survival in Advanced Melanoma

At 3 years, 40% of patients with advanced melanoma treated with pembrolizumab are alive regardless of whether they had been treated with ipilimumab or not, follow-up results from the KEYNOTE-001 study reported at the ASCO 2016 Annual Meeting.

Dabrafenib Plus Trametinib Continue to Show Survival Benefit in BRAF-mutant Metastatic Melanoma

Dabrafenib Plus Trametinib Continue to Show Survival Benefit in BRAF-mutant Metastatic Melanoma

The longest overall survival follow-up among randomized phase 3 trials evaluating BRAF and MEK inhibitors in patients with BRAF-mutant metastatic melanoma to date has shown the best 3-year outcome with dabrafenib plus trametinib to be in patients with normal LDH and fewer than 3 disease sites, according to a presentation at the ASCO 2016 Annual Meeting.

Potential Survival Advantage Observed for 177Lu-Dotatate in Midgut Neuroendocrine Tumors

Potential Survival Advantage Observed for 177Lu-Dotatate in Midgut Neuroendocrine Tumors

NETTER-1 trial results of the somatostatin analogue peptide, 177Lu-DOTA0-Tyr3-octreotate (177Lu-Dotatate), suggest a potential survival benefit in patients with advanced midgut neuroendocrine tumors (NETs), attendees at the ASCO 2016 Annual Meeting were told.

Evidence Mounts That Low-Dose Aspirin Improves Survival in CRC

Evidence Mounts That Low-Dose Aspirin Improves Survival in CRC

Greatest survival benefit observed for those taking the drug before their cancer diagnosis.

Tailored Dose-Dense Chemotherapy Improves Event-free Survival in High-Risk Breast Cancer

Tailored Dose-Dense Chemotherapy Improves Event-free Survival in High-Risk Breast Cancer

Tailored dose-dense chemotherapy significantly improved event-free survival and also showed efficacy in relapse-free and overall survival compared with standard adjuvant chemotherapy in patients with high-risk breast cancer, according to results of the phase 3 PANTHER study reported at the 2016 ASCO Annual Meeting.

Meta-analysis Confirms Lenalidomide Maintenance Prolongs Overall Survival in Multiple Myeloma

Meta-analysis Confirms Lenalidomide Maintenance Prolongs Overall Survival in Multiple Myeloma

Lenalidomide maintenance after high-dose melphalan and autologous stem cell transplant (ASCT) significantly prolonged overall survival in patients with multiple myeloma compared with no maintenance, a meta-analysis of 3 randomized controlled trials presented at the 2016 ASCO Annual Meeting has found.

Early Palliative Care Improves Quality of Life for Family Caregivers of Patients With Cancer

Early Palliative Care Improves Quality of Life for Family Caregivers of Patients With Cancer

The introduction of palliative care shortly after a patient is diagnosed with cancer is associated with improved quality of life.

Precision Medicine Linked to Better Outcomes in Early Trials

Precision Medicine Linked to Better Outcomes in Early Trials

Patients whose treatment was based on the molecular characteristics of their particular tumor had significantly better outcomes compared with patients who did not.

Pembrolizumab Improves Long-term Survival in Advanced Melanoma

Pembrolizumab Improves Long-term Survival in Advanced Melanoma

Four in 10 patients with newly diagnosed and previously treated advanced melanoma were alive 3 years after initiating pembrolizumab.

Vessel-Sparing Radiation Successfully Treats Prostate Cancer, Maintains Quality of Life

Radiation therapy delivered to the critical vessels surrounding the prostate can result in erectile dysfunction and bladder and renal irritation. Vessel-sparing radiation and an improved understanding of the anatomy of the prostate can reduce these effects.

Including Quality Measures In Treatment Regimens Increases Survival in Stage IIIA Non-Small Cell Lung Cancer

Including Quality Measures In Treatment Regimens Increases Survival in Stage IIIA Non-Small Cell Lung Cancer

When more quality measures are incorporated into patient care, survival rates for patients with stage IIIA non-small cell lung cancer (NSCLC) increase, but only 13% of eligible patients actually receive all 4 recommended quality measures.

Chemoradiotherapy Showed No Survival Benefit Over Chemotherapy in Locally Advanced Pancreatic Cancer

Researchers discovered no survival benefit of chemoradiotherapy over chemotherapy in treating locally advanced pancreatic cancer in the LAP01 Randomized Clinical Trial.

Older Patients With Lung Cancer Experience High Survival After Surgery

Older Patients With Lung Cancer Experience High Survival After Surgery

Results from this study showed that 5-year survival for older patients after surgery for lung cancer is favorable. Based on these results, surgeons might be better equipped to individualize care for this older population.

Radiotherapy Plus Hormone Therapy Improves Long-term Survival for Patients With Prostate Cancer

Radiotherapy in combination with anti-androgen hormone therapy halves the risk of death from prostate cancer 15 years after diagnosis compared with hormone therapy alone.

Study Identifies Factors Associated With Depression, Anxiety in Family Caregivers

Study Identifies Factors Associated With Depression, Anxiety in Family Caregivers

A recent study examined depression and anxiety among family caregivers of patients with incurable cancer and sought to identify factors linked to these symptoms.

Young Adult Survivors of Childhood Cancers Experience Accelerated Aging

Chronic conditions commonly affect long-term quality of life for survivors of childhood cancer who are in their young adult years.

Survival in Head and Neck Cancer Increased With Nivolumab Over Chemotherapy

The immunotherapy drug nivolumab conferred a survival benefit in patients with head and neck cancer over standard chemotherapy.

Experimental Targeted Therapy Succeeds in Rare Pediatric Cancer

The experimental treatment LOXO-101 led to remarkable improvement for a 20-month-old girl whose rare pediatric cancer did not respond to surgery or chemotherapy.

E-Cigarette Poisonings on the Rise Among Young Children

E-Cigarette Poisonings on the Rise Among Young Children

Swallowing the liquid nicotine appears to affect children under 6 the most, and calls to poison control centers about accidental ingestion have sharply increased.

VATS Associated With Less Post-op Pain, Better QoL for Stage 1 NSCLC

VATS Associated With Less Post-op Pain, Better QoL for Stage 1 NSCLC

Video-assisted thoracoscopic surgery (VATS) is associated with less postoperative pain and better quality of life than anterolateral thoracotomy for the first year of surgery in patients with stage I NSCLC.

Delaying Radiation Therapy for Women With Early Stage Breast Cancer Increased Risk of Recurrence

Delaying Radiation Therapy for Women With Early Stage Breast Cancer Increased Risk of Recurrence

Delayed radiation therapy (RT) after surgery significantly increased the risk of recurrent disease in women treated for very early breast cancer.

Low-dose Aspirin Appears to Improve Cancer Survival and Metastasis

Low-dose Aspirin Appears to Improve Cancer Survival and Metastasis

A low-dose of aspirin could increase survival by up to 20% and help stop metastasis for patients receiving cancer treatment.

Ixazomib Improves Progression-Free Survival in Multiple Myeloma

Ixazomib Improves Progression-Free Survival in Multiple Myeloma

Progression-free-survival was improved in all prespecified patient groups, including those with high-risk cytogenetic abnormalities.

Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts

Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts

E-cigarettes have a strong potential to improve population health by reducing or displacing cigarette use. A team of international experts urged the US FDA to have a broad perspective when it comes to regulating e-cigarettes.

AYA Patient Survivorship Program Created to Improve Quality of Life

AYA Patient Survivorship Program Created to Improve Quality of Life

An AYA patient survivorship program jointly designed by a cancer institute and a community organization educates patients about their oncologic history and the effects of therapy, as well as provides resources to improve quality of life.

SES, Physical Health Features Linked to Depression Among CRC Survivors

SES, Physical Health Features Linked to Depression Among CRC Survivors

Socioeconomic status and features of physical health rather than tumor characteristics were associated with symptoms of depression among long-term survivors of colorectal cancer.

Survival Is Better With SRS Than With WBRT for NSCLC or Breast Cancer Metastases to the Brain

Longer survival was achieved with stereotactic radiosurgery (SRS) alone than with whole-brain radiation therapy (WBRT) in patients with fewer than 4 brain metastases from NSCLC or breast cancer.

Chemotherapy and Radiotherapy Combination Prolongs Survival in Low-grade Glial Brain Cancer

The addition of chemotherapy to radiation therapy prolonged survival in adults with grade 2 glial brain tumors.

Survival Prolonged by Continuing Ceritinib Beyond Disease Progression in Non-small Cell Lung Cancer

Continuation of ceritinib therapy beyond disease progression was associated with prolonged survival, according to results from a retrospective study of the use of ceritinib to treat advanced ALK-positive NSCLC.

Offer Smoking Cessation Help With Lung Cancer Screening for Patients Who Smoke

Smokers who visit a clinician for lung cancer screening should also be encouraged to quit smoking at that visit. Evidence-based behavioral strategies should be used, at each visit, to motivate smokers to quit.

AACR: Regular Pre-Diagnosis Exercise Ups Prostate Cancer Survival

AACR: Regular Pre-Diagnosis Exercise Ups Prostate Cancer Survival

Researchers found that men with prostate cancer who had exercised regularly had the best outcomes.

Breast Cancer Therapy and Cardiotoxicity Risk in Older Women

Breast Cancer Therapy and Cardiotoxicity Risk in Older Women

A study examined the relation between various forms of breast cancer therapies and risk of congestive heart failure.

New Therapy Holds Promise for Patients With Ewing Sarcoma

Two new compounds suppress tumor growth in cell culture and mouse xenograft models of Ewing sarcoma, a rare pediatric cancer. These 2 compounds are similar to mithramycin, also known as picamycin, a drug no longer manufactured due to its toxicity.

Metformin May Reduce Cancer Mortality Risk for Women

Metformin May Reduce Cancer Mortality Risk for Women

Older women with diabetes and cancer taking metformin saw an increase in survival.

Higher Radiation Doses May Not Improve Survival in Localized Prostate Cancer

New technology has enabled doctors to administer higher doses of radiation to prostate cancer tumors with fewer side effects; however, escalating the dose of radiation may not help patients with localized prostate cancer in the long term.

Patients With Hodgkin Lymphoma Resistant to Brentuximab Vedotin Have Poor Outcomes

Patients With Hodgkin Lymphoma Resistant to Brentuximab Vedotin Have Poor Outcomes

Patients with classical Hodgkin lymphoma who are resistant to the CD30-directed antibody-drug conjugate brentuximab vedotin have poor outcomes.

The Relationship Between Location of Metastases and Overall Survival in Men with mCRPC

The Relationship Between Location of Metastases and Overall Survival in Men with mCRPC

Site of metastasis is key to the length of time a patient can survive metastatic castration-resistant prostate cancer (mCRPC).

Higher Treatment Volumes at Radiation Facilities Lead to Improved Overall Survival in Prostate Cancer

Higher Treatment Volumes at Radiation Facilities Lead to Improved Overall Survival in Prostate Cancer

Among men with aggressive prostate cancer, overall survival (OS) rates improve when they receive radiation treatment at facilities that frequently perform the treatment.

Anxiety and Depressive Symptoms Are Increased in Pediatric Survivors of Acute Lymphoblastic Leukemia

Emotional distress during and after undergoing chemotherapy for ALL affects a significant percentage of children with the disease.

Prolonged Nightly Fasting May Reduce Breast Cancer Recurrence Risk

Prolonged Nightly Fasting May Reduce Breast Cancer Recurrence Risk

Prolonged nightly fasting may reduce the risk of recurrence for patients with breast cancer.

The Samfund: Helping Young Adult Patients Navigate the Financial Impact of Cancer Care

The Samfund: Helping Young Adult Patients Navigate the Financial Impact of Cancer Care

The Samfund is a not-for-profit organization dedicated to easing the lasting financial effects of cancer treatments for young adults with the disease.

Surgery Improves Survival After Radiotherapy Failure in Men With Prostate Cancer

A complex surgical procedure to remove the prostate achieves excellent long-term survival for men with prostate cancer after radiation therapy has failed.

Temsirolimus Effective as Salvage Treatment in Patients With Relapsed/Refractory PCNSL

Temsirolimus Effective as Salvage Treatment in Patients With Relapsed/Refractory PCNSL

A weekly dose of temsirolimus 75 mg was found to be active in patients with relapsed/refractory primary CNS lymphoma (PCNSL); however, only some patients achieved long-term control.

Prognosis Poor for Women With Pregnancy-Associated Melanoma

Prognosis Poor for Women With Pregnancy-Associated Melanoma

Among women aged up to 49 years with a pregnancy-associated melanoma, recurrence rates were higher than seen in other groups.

Inflammatory Bowel Disease Can be Managed With Anti-TNF Therapy in Cancer Survivors

Patients who have had cancer recently can still be treated with antibodies against tumor necrosis factor for inflammatory bowel disease.

Study Findings Show Possible Association Between PreLabor Cesarean Delivery and Risk for ALL in Young Children

The finding that prelabor cesarean delivery may have a correlation with acute lymphoblastic leukemia (ALL) may offer new targets for research into preventing cancer.

Model Demonstrates Benefits of MRI Screening for Breast Cancer in Survivors of Childhood Hodgkin Lymphoma

Model Demonstrates Benefits of MRI Screening for Breast Cancer in Survivors of Childhood Hodgkin Lymphoma

Female survivors of childhood Hodgkin lymphoma (HL) who received chest radiation can reduce their risk of breast cancer through early screening.

High Neutrophil to Lymphocyte Ratio Prognostic in Early Breast Cancer

High Neutrophil to Lymphocyte Ratio Prognostic in Early Breast Cancer

High neutrophil to lymphocyte ratio (NLR) is linked to worse prognosis in Caucasian patients with early breast cancer.

Reliance on PET to Detect Lung or Esophageal Cancer Recurrence May Lead to Overuse of the Imaging Modality

In posttreatment follow-up of lung and esophageal cancer, PET scans might be overused to detect cancer recurrence. Furthermore, PET scan use to detect recurrence does not increase survival.

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