A review of radiotherapy-induced hypopituitarism

A review of radiotherapy-induced hypopituitarism

Some patients undergoing radiotherapy for cancers of the head, neck, and brain are at risk for endocrinopathies. This article reviews the risks, detection, and management of radiotherapy-induced hypopituitarism.

Lifestyle choices may lower metabolic syndrome risk of for cancer survivors

Lifestyle choices may lower metabolic syndrome risk of for cancer survivors

A study conducted by researchers based at the St. Jude Children's Research Hospital has determined that healthy lifestyle choices can help cancer survivors avoid the metabolic syndrome.

Colorectal cancer survival associated with higher vitamin D levels

Colorectal cancer survival associated with higher vitamin D levels

Colorectal cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a study shows.

Lack of Trust in One's Doctor Affects Health of Emotionally Vulnerable Cancer Patients

Lack of Trust in One's Doctor Affects Health of Emotionally Vulnerable Cancer Patients

Patients' relationship with their doctor and their attachment style may affect their physical and mental well-being, especially during vulnerable times such after a cancer diagnosis, according to a new study.

Exercise And Nutrition Counseling Plus Palliative Care Improves Quality Of Life For Patients With Cancer

Exercise And Nutrition Counseling Plus Palliative Care Improves Quality Of Life For Patients With Cancer

A team of researchers in Canada concludes that combining exercise, nutritional counseling, and symptom control to palliative care from diagnosis helps to improve the quality of life for patients with cancer.

Noninvasive advanced image analysis may improve care for lung cancer patients

Lung cancer patients could receive more precise treatment, and their progress could be better tracked by using a new high-tech method of non-invasive medical imaging analysis, according to a new study.

Rates of observation as prostate cancer management vary

Rates of observation as prostate cancer management vary

Rates of observation as management for low-risk prostate cancer vary widely, and primary ADT is not tied to better survival for men with localized prostate cancer.

Robot-assisted surgery effective in controlling prostate cancer for 10 years

Robot-assisted surgery effective in controlling prostate cancer for 10 years

Results of a new study show that robot-assisted surgery to remove cancerous prostate glands is effective in controlling the disease for 10 years.

Managing follicular lymphoma

Managing follicular lymphoma

Changes in how follicular lymphoma is managed have led to substantial improvement in prognosis and over all survival for patients with the disease.

New drug active against most aggressive type of lung cancer

Scientists have shown that a new drug could prove useful in treating small cell lung cancer, the most aggressive form of lung cancer.

Depressed men with prostate cancer have worse outcomes

Depressed men with prostate cancer have worse outcomes

Depressed men with a diagnosis of intermediate- or high-risk prostate cancer have worse overall outcomes.

Doctors steer prostate cancer treatment choices

Doctors steer prostate cancer treatment choices

Physicians who diagnosed low-risk prostate cancer had more influence over the decision to enter active surveillance than did the disease characteristics, according to a case review.

Radiation-induced toxicity risk in prostate cancer predicted by variations in key gene

Key genetic variants may affect how cancer patients respond to radiation treatments, according to a new study.

Study explores reasons for significant variations in blood cancer survival across Europe

Study explores reasons for significant variations in blood cancer survival across Europe

The EUROCARE study, the largest population-based study of survival in European blood cancer patients to date, analyzed data from 30 cancer registries, involving all patients with cancer diagnoses in 20 European countries.

DII may be a potential determinant of hospitalization duration among surgically treated patients with colorectal cancer

DII may be a potential determinant of hospitalization duration among surgically treated patients with colorectal cancer

The dietary inflammatory index may be used as a potential predictor of length of hospitalization among patients undergoing surgical treatment of colorectal cancer, according to a team of researchers at Jagiellonian University Medical College, in Krakow, Poland.

Latest findings give optimistic picture of breast cancer survival odds

Latest findings give optimistic picture of breast cancer survival odds

New findings from Fox Chase Cancer Center paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin.

New test predicts survival in patients with leukemia

New test predicts survival in patients with leukemia

Scientists have developed a test which accurately predicts the prognosis for patients with the most common form of leukemia.

Nanoliposome formulation improves drug delivery and survival in metastatic pancreatic cancer

The addition of MM-398, a novel nanoliposome formulation of irinotecan, to standard treatment improves survival for metastatic pancreatic cancer patients who have already received gemcitabine.

Insurer's study finds cost-effective way to treat cancer

Insurer's study finds cost-effective way to treat cancer

A new model for paying oncologists reduced cancer care costs by 34% without changing how well patients fared after treatment, according to a study conducted by UnitedHealthcare.

Genetics could factor into racial disparity in colon cancer

Genetics could factor into racial disparity in colon cancer

African-Americans are half as likely to have the genetic marker associated with improved survival.

Telephone call is effective support when breast cancer treatment includes weight loss

A series of simple telephone calls can make a profound difference in helping women with breast cancer to meet their treatment goals for weight loss.

Combination treatment improves recurrence and survival in ovarian cancer

A new combination of medications for treatment of recurrent ovarian cancer showed improved response rates, increased the rate of tumor shrinkage, and prolonged the time until cancers recurred

Benefits of trastuzumab outweigh the risk of harm in advanced breast cancer

A new systematic review shows that treatment with the breast cancer drug trastuzumab is associated with prolonged survival in women with advanced breast cancer, but the risk of developing heart problems also increases.

Study Results Demonstrate A New Prostate Cancer Treatment

Study Results Demonstrate A New Prostate Cancer Treatment

A new study is suggesting a different approach to treating prostate cancer. Researchers at Comprehensive Cancer Centers of Nevada conducted a study in which 790 men with advanced stages of prostate cancer received early chemotherapy.

Bisphenol A Triggers Changes in Rats That May Lead to Breast Cancer

Bisphenol A Triggers Changes in Rats That May Lead to Breast Cancer

New research presents another cause for concern in regard to the chemical bisphenol A (BPA). The study is the first to examine what impact BPA has on the DNA of mammary glands as they age.

Risk of hospitalization increased for childhood cancer survivors, even years after treatment

Survivors of childhood cancers were hospitalized more often and had longer hospital admissions many years after cancer treatment was completed, compared with the general population.

Early initiation of palliative care support improves caregiver quality of life and patient survival

Early initiation of palliative care support improves caregiver quality of life and patient survival

The earlier a specific phone-based, palliative care support program can be introduced to caregivers, the better they will be able to cope with the caregiving experience, according to research conducted by University of Alabama at Birmingham School of Nursing investigators.

Answering the unanswerable

Answering the unanswerable

Sometimes the best answer to a patient's question is quiet support. Can you recognize when no words are needed?

LDCT screening for lung cancer does not induce long-term anxiety or distress

A review of studies that evaluated patient-centered outcomes of LDCT screening for lung cancer found that overall quality of life is not significantly impacted in persons who undergo the screening procedure.

Study demonstrates improved diagnosis and outcomes with LDCT

A study using a 5-year LDCT screening protocol showed good adherence and patient survival outcomes in persons at high risk of developing lung cancer.

'Financial Toxicity' tool created to assist cancer patients

'Financial Toxicity' tool created to assist cancer patients

A four-step process involving 155 patients with cancer was used to develop patient-reported outcome measure.

A few circulating tumor cells can indicate metastasis risk

A simple, noninvasive blood test matched with state-of-the-art molecular imaging of individual cells could help oncologists understand their patients' chances of survival.

Molecular breast imaging protocol unmasks more cancer in advanced cases

Patients with advanced breast cancer that may have spread to their lymph nodes could benefit from a more robust dose of a molecular imaging agent when undergoing lymphoscintigraphy.

Limiting carbs may reduce breast cancer recurrence in some women

Limiting carbs may reduce breast cancer recurrence in some women

Reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the insulin-like growth factor-1 (IGF1) receptor, according to a new study.

Diets high in dairy may up colon cancer survival

Diets high in dairy may up colon cancer survival

A diet rich in dairy products may slightly extend the lives of people diagnosed with colon cancer, a new study suggests.

Advanced heart imaging raises lifetime cancer risk of children

Children who undergo repeated complex imaging tests that deliver higher doses of radiation may have a slightly increased lifetime risk of cancer, according to new research.

Study Compares Outcomes for Treatments of Uncommon Eye Cancer

Study Compares Outcomes for Treatments of Uncommon Eye Cancer

Treatment with selumetinib resulted in improved progression-free survival time and tumor response rate compared with chemotherapy, but no improvement was seen in overall survival. Furthermore, the modest improvement in clinical outcomes was accompanied by a high rate of adverse effects.

National Childhood Cancer Strategies Are Needed for Low- and Middle-Income Countries

National Childhood Cancer Strategies Are Needed for Low- and Middle-Income Countries

Cancer represents the leading cause of nonaccidental death among children in an increasing number of middle-income countries. Meaningful declines in global childhood cancer mortality will require moving toward the establishment of national childhood cancer strategies.

Restoring gene function reverses cancer in common childhood leukemia

Restoring gene function reverses cancer in common childhood leukemia

Researchers in Melbourne, Australia, have shown that switching off a gene called Pax5 could cause a type of leukemia, and restoring its function could cure the disease.

Breast cancer surgery trends in Canada similar to that in United States

Breast cancer surgery trends in Canada similar to that in United States

To better understand breast cancer surgery trends in Canada, researchers reviewed data from the Canadian Institute for Health (CHI) on 57,840 women who underwent breast cancer surgery between 2007 and 2010.

Specialized apps extend the reach of community

Specialized apps extend the reach of community

In Alabama, smartphone technology brings regional resources to patients with cancer; in New Jersey, it motivates adolescent survivors to exercise.

Hospitalization rate greater for childhood cancer survivors

Hospitalization rate greater for childhood cancer survivors

A higher hospital admission rate is seen for childhood survivors, with highest rates for survivors of neuroblastoma and bone tumors.

Gene mutation lowers breast cancer survival

Gene mutation lowers breast cancer survival

Women with a specific gene mutation have a higher risk of dying from a type of breast cancer, according to a study that raised prospects of targeted drugs.

Growing pains noted in survey on moving toward quality patient-centered care

In order to meet new cancer program accreditation standards, institutions have placed new focus on patient navigation, psychosocial distress screening, and survivorship care plans.

Hyperfractionated radiotherapy improves overall survival in patients with head and neck cancer

Hyperfractionated radiotherapy improves overall survival in patients with head and neck cancer

A multi-institutional, randomized phase III trial of fractionation in locally advanced head and neck cancer demonstrated improved local-regional control and improved overall survival with no increase in late toxicity with hyperfractionated radiation therapy.

Patient risk information improves mammogram interpretation

Patient risk information improves mammogram interpretation

A research group's findings demonstrate a role for risk profiling in the interpretation of mammograms. The new approach takes into account a woman's health risk profile, which may reduce both the number of missed cancers and false positives.

Tobacco companies to introduce e-cigarettes

Tobacco companies to introduce e-cigarettes

Big tobacco companies are jumping into the rapidly expanding and lucrative e-cigarette market.

Patient navigation: Is it a process or person?

Patient navigation: Is it a process or person?

Optimum, risk-based survivorship health care is a provision of lifelong care that integrates cancer and survivorship experiences in survivors' overall health care needs.

Lowering carb intake could help reduce breast cancer risk

Lowering carb intake could help reduce breast cancer risk

Concerned about the associations between obesity, diabetes, and cancer risk, researchers examined the links between carbohydrate intake and breast cancer risk.

Genomics of lung cancer progression vary widely

Tumor sequencing of several different lung cancers and their surrounding tissue complicates the prevailing theory of linear lung cancer progression and offers new insights for management of this deadly cancer.

Research Demonstrates That Chinese Herbal Medicine Can Treat Cancer

Research Demonstrates That Chinese Herbal Medicine Can Treat Cancer

In a review of study results from 2,964 human clinical trials, Australia and Chinese university scientists found that Chinese herbal medicine offers significant treatment for most types of cancers.

Nearly one-quarter of children in remission from ALL miss doses of maintenance medication

Nearly one-quarter of children in remission from ALL miss doses of maintenance medication

Children in remission from acute lymphocytic leukemia (ALL) must take 6-mercaptopurine (6MP) for 2 years to prevent disease reemergence; however, a study shows that an estimated 25% of children in remission are not taking this essential maintenance medication at least 90% of the time, tripling their relapse risk.

No clinic, no problem: Virtual navigation program extends the service to head and neck cancer

No clinic, no problem: Virtual navigation program extends the service to head and neck cancer

A team of clinicians proposed a virtual navigation system that would allow patients to follow the same pathway as clinic patients but without the formal clinic setting.

Oncology nursing collaboration delivers improved patient experience

Oncology nursing collaboration delivers improved patient experience

A team of nurses at Torrance Memorial Medical Center identified developed a collaborative approach aimed at improving the cancer patient experience at their community hospital.

Integrative model of nurse navigation enhances survivorship care

Integrative model of nurse navigation enhances survivorship care

A new cancer diagnosis encompasses multiple physician visits and procedures, and can produce overwhelming stress for all involved.

Survivorship program helps patients embrace life after treatment ends

Survivorship program helps patients embrace life after treatment ends

Nurses at a community cancer center in Minneapolis described the Celebration of Life Cancer Survivorship Evening Program they developed in a presentation at the 2014 NCONN Conference.

The evolution of psychosocial care in cancer centers

The evolution of psychosocial care in cancer centers

Ongoing efforts are being made to address the distress experienced by patients with cancer and new guidelines are now incorporating this care into standard practice.

ACS predicts that cancer survivors will number nearly 19 million by 2024

The number of cancer survivors in the United States, currently estimated at 14.5 million, will grow to almost 19 million by 2024, according to an updated report by the American Cancer Society.

New care guidelines issued for prostate cancer survivors

New care guidelines issued for prostate cancer survivors

New guidelines have been developed for clinical follow-up care for prostate cancer survivors. Issues addressed include health promotion, surveillance for recurrence, and new primaries.

The Healing Arts Program at Montefiore: A collaboration that heals patients and nurses

The Healing Arts Program at Montefiore: A collaboration that heals patients and nurses

A major medical center in New York City uses a program of arts and music to help patients through their treatments. The program is even being used to give nurses a chance to de-stress.

HBV therapy may reduce liver cancer risk

HBV therapy may reduce liver cancer risk

Antiviral treatment for hepatitis B virus (HBV) may be associated with a lower risk of hepatocellular carcinoma, researchers reported.

MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma

The largest clinical study to evaluate breast cancer screening of female survivors of childhood Hodgkin lymphoma, showed that MRI detected invasive breast tumors at very early stages, when cure rates are expected to be excellent.

ACS Releases Long-Term Primary Care Guidelines for Prostate Cancer Survivors

ACS Releases Long-Term Primary Care Guidelines for Prostate Cancer Survivors

The American Cancer Society released a set of guidelines addressing the long-term primary care for survivors of prostate cancer. The guidelines outline follow-up care, monitoring for recurrence, and screening for secondary primary cancers. They also reiterate the need to educate survivors about physical exercise and smoking cessation.

Antiviral therapy may prevent liver cancer in patients with hepatitis B

Antiviral therapy may prevent liver cancer in patients with hepatitis B

Researchers have found that antiviral therapy may be successful in preventing hepatitis B virus from developing into the most common form of liver cancer, hepatocellular carcinoma (HCC).

ASCO: Fish and exercise can thwart colon cancer recurrence

ASCO: Fish and exercise can thwart colon cancer recurrence

The likelihood that patients will suffer a return of colon cancer more than doubles if they eat fish less than twice a week, or if they get less than 60 minutes of moderate exercise a week.

For patients with AIDS-related lymphomas, identification of CNS involvement at diagnosis does not affect overall survival

For patients with AIDS-related lymphomas, identification of CNS involvement at diagnosis does not affect overall survival

Patients with AIDS-related lymphomas may face an increased risk of CNSi compared to other lymphomas. Researchers report that CNSi - identified at the time of an ARL diagnosis - does not appear to have an impact on overall survival. The vast majority of patients have stage IV disease at the time of presentation.

Prolaris test predicts prostate cancer mortality risk

The Prolaris test distinguished newly diagnosed patients who were likely to die from prostate cancer within 10 years from those with lower risk disease.

Early detection and aging to grow cancer survivorship in United States

Early detection and aging to grow cancer survivorship in United States

By 2024, the number of Americans with a history of cancer is expected to grow to 19 million.

Newly identified brain cancer mutation may can aid drug development

Researchers have identified a genetic mutation in brain cancer tumor cells that plays a role in both the growth and the death of the cell.

Insurance coverage associated with improved cancer-specific outcomes

Insurance coverage associated with improved cancer-specific outcomes

Health insurance coverage is associated with improved cancer-specific outcomes for young adults, according to a study.

Interruption of biological rhythms during chemotherapy worsens side effects

Chemotherapy disrupts circadian rhythms leading to a higher risk for clinically relevant fatigue or weight loss.

Does Early Integration of Palliative Care and Cancer Treatment Benefit Patients?

Does Early Integration of Palliative Care and Cancer Treatment Benefit Patients?

Immediately integrating cancer treatment and palliative care might improve survival at 1 year in patients with advanced cancers, suggest findings from the ENABLE III randomized controlled trial, presented at the 2014 ASCO Annual Meeting.

Patients taking pazopanib for advanced renal cancer report better quality of life

Patients taking pazopanib for advanced renal cancer report better quality of life

Two oral targeted drugs approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, according to results of a large international clinical trial led by researchers at Dana-Farber Cancer Institute.

ASCO: Ramucirumab extends survival for NSC lung cancer

ASCO: Ramucirumab extends survival for NSC lung cancer

For patients with non-small-cell lung cancer who have relapsed after initial treatment, the addition of the anti-angiogenesis drug ramucirumab to standard docetaxel chemotherapy extends survival.

Expert commentary: 'Apology bill' shields health care providers' apologies from malpractice suits in Wisconsin

Expert commentary: 'Apology bill' shields health care providers' apologies from malpractice suits in Wisconsin

Apologies by health care workers are protected from being used against them in court by a new law enacted in Wisconsin, one of more than 35 states to enact such a law.

Navigator Notes: The role of the navigator and its effect on health care reform

Navigator Notes: The role of the navigator and its effect on health care reform

Nurse navigators can offer more than just helping patients keep their appointments and maintain their lives. Navigators can help the health care system function more effectively.

Gene mutation identified for aggressive form of pancreatic cancer

A mutated gene common to adenosquamous carcinoma tumors has been identified. It is the first known unique molecular signature for this rare, but particularly virulent, form of pancreatic cancer.

How modern medicine can help patients achieve a "good" death

Overall quality of death of cancer patients who die in an urban Canadian setting with ready access to palliative care was found to be good to excellent in a majority of cases, helping to dispel the myth that suffering at the end of life is inevitable.

Lung cancer screening may prompt smoking cessation

Lung cancer screening may prompt smoking cessation

Smokers with abnormalities detected in lung cancer screening are significantly more likely to quit smoking, according to research.

Adolescent and Young Adult Cancer Survivors Report Cognitive, Sexual Late Effects

Adolescent and Young Adult Cancer Survivors Report Cognitive, Sexual Late Effects

Adult and young adult cancer survivors face cognitive and sexual late effects from cancer and its treatment, according to data compiled from an online cancer survivorship care planning tool presented at the 2014 ASCO Annual Meeting.

Docetaxel + ADT ups survival in metastatic prostate cancer

Docetaxel + ADT ups survival in metastatic prostate cancer

Upfront standard androgen deprivation therapy plus six cycles of docetaxel significantly improves overall survival compared with ADT alone in men with metastatic hormone-sensitive prostate cancer.

Baseline hypertension, ASIs affect hypertension, survival during VEGF inhibitor therapy

Baseline hypertension, ASIs affect hypertension, survival during VEGF inhibitor therapy

Baseline hypertension and BMI can affect worsening hypertension among patients administered vascular endothelial growth factor signaling pathway inhibitors, according to research presented at the 2014 ASCO Annual Meeting.

New way to predict response to chemotherapy in triple-negative breast cancer

New way to predict response to chemotherapy in triple-negative breast cancer

The presence of tumor-infiltrating lymphocytes ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer, according to a new study.

Pancreatic cancer to become second-leading cause of cancer death by 2030

An analysis projects pancreatic and liver cancers will become second and third leading causes of cancer-related death in the United States by 2030, respectively, behind lung cancer, which will remain the number one killer.

Genetic alterations in lung cancer help select treatment and may improve survival

Genetic alterations of lung cancer tumors were identified through multiplexed testing, and these alterations were helpful in selecting targeted treatments.

Novel target identified for chemotherapy-resistant leukemia cells

By targeting a particular receptor, chemotherapy-resistant cancer cells can be killed in an acute form of childhood leukemia, according to new research.

Molecular tumor board helps in advanced cancer cases

With accelerating development of personalized cancer treatments matched to a patient's DNA sequencing, proponents of these treatments say frontline physicians increasingly need help finding the best individualized therapy.

Most adults aware of e-cigarettes and perceive them as less harmful

Most adults aware of e-cigarettes and perceive them as less harmful

Just over half believe them to be less harmful than cigarettes, according to a study.

Success with lung cancer treated by novel repeat radiation approach

An old idea of retreating lung tumors with radiation is new again, especially with the technological advances seen in radiation oncology over the last decade.

Better sleep linked to longer survival in advanced breast cancer

Better sleep linked to longer survival in advanced breast cancer

A new study reports that sleep efficiency, a ratio of time asleep to time spent in bed, is predictive of survival time for women with advanced breast cancer.

Study raises doubts on value of additional imaging before colorectal cancer surgery

Among patients with a certain type of colorectal cancer with limited spread to the liver, imaging using PET and CT before surgery did not significantly change the surgical treatment of the cancer, compared with CT alone.

Experimental treatment shows early promise for advanced neuroblastoma in children

Tumors shrank or disappeared and disease progression was temporarily halted in 15 children with advanced neuroblastoma enrolled in a safety study of an experimental antibody.

Immunogenic mutations in tumor genomes tied to increased survival

In a new study, researchers examined the largest collection of tumor samples to date to predict patient-specific tumor mutations that may activate the patient's immune system, paving the way for more successful, personalized cancer immunotherapy.

How men used humor to cope with the devastating physical consequences of penile cancer

How men used humor to cope with the devastating physical consequences of penile cancer

Despite the seriousness of cancer, patients may use humor as part of their coping armamentarium. They may also appreciate when their health care team does, too, as these researchers found.

Can e-cigarettes help smokers quit?

Can e-cigarettes help smokers quit?

One study by British researchers suggests yes, but not all experts agree.

Human fat may be a Trojan horse in the fight against brain cancer

Stem cells derived from human body fat have been successfully used to deliver biologic treatments directly to the brains of mice with the most common and aggressive form of brain tumor, significantly extending their lives.

Higher vitamin D linked to higher survival of cancer

Higher vitamin D linked to higher survival of cancer

Cancer patients who have higher levels of vitamin D at diagnosis tend to have better survival rates and remain in remission longer than patients who are vitamin D-deficient, according to a new study.

Survival benefit associated with aggressive prostate cancer treatment weakens with comorbidity

Survival benefit associated with aggressive prostate cancer treatment weakens with comorbidity

For men with early-stage prostate cancer, the cancer-specific survival benefit associated with aggressive prostate cancer treatment is reduced with increasing comorbidity, according to a study.

Hemipelvectomy: Providing evidence-based nursing care

Meeting the challenges of the significant morbidity, functional impairment, and alterations in body image in patients undergoing this surgical resection.

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