Multiple studies are exploring whether e-cigarettes help smokers quit or continue smoking

Multiple studies are exploring whether e-cigarettes help smokers quit or continue smoking

Research continues into whether e-cigarettes help smokers quit or actually worsen their habit.

Post-cancer survival up for Americans, but disparities remain

Post-cancer survival up for Americans, but disparities remain

Study shows biggest improvements in post-cancer survival for people diagnosed between ages 50 and 64.

Healthful lifestyle advice needed by cancer survivors

Healthful lifestyle advice needed by cancer survivors

Oncology care teams should provide more guidance on lifestyle change as part of survivorship care, according to recent research.

Considerable practice variation among surgeons in selecting patients for radical prostatectomy

Considerable practice variation among surgeons in selecting patients for radical prostatectomy

Variation was observed at a high-volume center when surgeons selected patients with low-risk prostate cancer to undergo radical prostatectomy, according to a study.

The unmet needs of cancer survivors: Quantifying the long-term effects of cancer

The unmet needs of cancer survivors: Quantifying the long-term effects of cancer

Long-lasting effects of cancer can plague patients for years after they complete their treatments. In this study, researchers sought to measure which problems plagued patients the most and for the longest time.

ASCO endorses ACS recommendations for prostate cancer survivor care

ASCO endorses ACS recommendations for prostate cancer survivor care

Guideline outlines recommended follow-up care for prostate cancer survivors

Adult survivors of pediatric cancer who underwent brain irradiation at risk for hormone deficiencies

Adult survivors of pediatric cancer who underwent brain irradiation at risk for hormone deficiencies

Adult survivors of pediatric cancer are at risk for developing pituitary hormone deficiencies that may worsen their health and quality of life.

Potential therapeutic strategy against a very aggressive children's bone cancer

Inhibiting the protein Sirtuin1 could play a part in fighting Ewing sarcoma, a common bone cancer in adolescents and children.

Patient treatment: The constancy of vulnerability

Patient treatment: The constancy of vulnerability

Transitions from one stage of cancer care to another are pivotal points of vulnerability for patients. The most significant point comes at the end of treatment, as patients face life forever changed.

Research promising for reducing risk of breast cancer spreading to the brain

New research seeks to better understand why breast cancer spreads to the brain, with the goal of developing a way to reduce the risk of this phenomenon.

Children of melanoma survivors need better sun protection

A recent, groundbreaking new study found that children of melanoma survivors are not adhering to sun protection recommendations.

Biological factors account for most of the variations in breast cancer survival rates

A study of approximately 375,000 U.S. women with invasive breast cancer showed differences in likelihood of diagnosis occurring at an early stage, and survival after stage I diagnosis, based on by race and ethnicity.

Nutrition intervention leads to dietary behavior changes in Latina breast cancer survivors

Nutrition intervention leads to dietary behavior changes in Latina breast cancer survivors

An intervention aimed at an under-represented group of Latina breast cancer survivors helped encourage better eating habits and nutrition.

Novel tool predicts postoperative liver cancer recurrence after transplant

The risk of disease recurrence in liver cancer patients who have undergone a liver transplant can now be more accurately calculated, thanks to new tool.

Higher vitamin D levels associated with markedly improved survival in advanced colorectal cancer

Higher vitamin D levels associated with markedly improved survival in advanced colorectal cancer

Patients in a a phase III study with higher vitamin D levels demonstrated better outcomes after treatment for their colorectal cancer with chemotherapy and targeted therapy.

Combination therapy can reduce chance of recurrence from small HER2+ breast tumors

Women with stage 1 HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were unlikely to suffer cancer recurrence within 3 years of treatment.

Stereotactic body radiation therapy (SBRT) plus chemotherapy improves survival among patients with stage 4 lung cancer

Combining stereotactic body radiation therapy (SBRT) with a specific chemotherapy regimen more than doubled survival rates for certain patients with stage 4 lung cancer, according to recent research data.

Single genetic abnormality important in Ewing sarcoma

Single genetic abnormality important in Ewing sarcoma

Better understanding of the two distinct processes at the heart of the genetic abnormality driving Ewing sarcoma development could lead to new, more effective therapies.

Women with atypical hyperplasia are at higher risk of breast cancer

A new study has better established the future risk of developing breast cancer for those with atypical hyperplasia of the breast.

Test predicts response to treatment for graft-versus-host disease (GVHD)

A new test may reveal which patients will respond to treatment for graft-versus-host disease (GVHD), a serious complication that can arise from stem cell SCT.

Risk for leukemia after treatment for early stage breast cancer higher than reported

According to results of a new, retrospective study, the risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer is double that previously reported.

International collaboration sets stage for better lung cancer surgery outcomes

The Society of Thoracic Surgeons (STS) and the European Society of Thoracic Surgery (ESTS) plan to link their outcomes data on chest procedures, in an effort to improve patient care.

Laparoscopic surgery for bladder cancer leads to good long-term cancer control

The long-term survival rates following laparoscopic surgery for bladder cancer are not unlike survival rates for open surgery, according to research.

Trastuzumab improves long-term survival of HER2-positive breast cancer patients

Trastuzumab significantly improves the long-term survival of HER-2 positive breast cancer patients, according to a large national study.

Effectiveness of drugs to prevent hepatitis among patients receiving chemotherapy

Use of the antiviral drug entecavir resulted in a lower incidence of hepatitis B virus (HBV)-related hepatitis and HBV reactivation among patients with lymphoma undergoing a certain type of chemotherapy.

Using genomic correlates of radiotoxicity to predict patient outcomes

Using genomic correlates of radiotoxicity to predict patient outcomes

Radiogenomics is maturing into a predictor of patients' likelihood of experiencing radiotoxicities and late radiation effects.

Cancer survivors face unmet disease- and treatment-related physical, mental needs

Cancer survivors face unmet disease- and treatment-related physical, mental needs

Many cancer survivors face disease- and treatment-related physical and mental challenges even decades after being cured of their disease.

Time to treatment initiation increasing for patients with head and neck cancer

Time to treatment initiation increasing for patients with head and neck cancer

Biggest increase for time to treatment initiation seen for head and neck cancer patients with advanced disease, chemoradiation, or undergoing treatment at academic center.

Hispanic women less likely to survive endometrial uterine cancer

Hispanic women in the United States were significantly less likely to survive endometrial uterine cancer than non-Hispanic white women.

Young adults with acute lymphoblastic leukemia (ALL) benefit from therapies developed for children

There is increasing evidence that adolescent and young adult patients with acute lymphoblastic leukemia (ALL) tend to fare better when treated with high-intensity pediatric protocols than standard adult regimens.

Older patients with breast cancer still undergo radiation despite its limited benefit

Women over 70 years with early stage breast cancer are very likely to receive radiation therapy, despite evidence of that it might not be the best form of treatment.

Mistletoe: The holiday plant is making headlines as an alternative cancer treatment

Mistletoe: The holiday plant is making headlines as an alternative cancer treatment

Most people know of the traditional use of mistletoe to get a kiss from a loved one during the Christmas holiday. However, US oncologists are discovering a new use for the plant as a CAM treatment for cancer.

New kind of targeted drug is promising for patients with leukemia

New kind of targeted drug is promising for patients with leukemia

Patients with advanced leukemia, when treated with a new type of cancer therapy that blocks mutated IDH2 protein, showed dramatic results in a clinical trial.

Investigational cellular therapy promising for pediatric ALL and for lymphoma

Pediatric patients with acute lymphoblastic leukemia (ALL) showed a 90% response rate from the first trials testing an investigational personalized cellular therapy known as CTL019.

Immunotherapy shows clinical benefit in relapsed transplant recipients

Immunotherapy shows clinical benefit in relapsed transplant recipients

Almost half of patients with blood cancer who had relapsed following allogeneic stem cell transplantation benefitted from treatment with the immune checkpoint blocker ipilimumab.

Experience counts with radiation for head and neck cancer

The effectiveness of radiation therapy used to treat head and neck cancer could depend in part on clinician experience, according to a new study.

Managing oral side effects of irinotecan therapy

Managing oral side effects of irinotecan therapy

Is there an effective way to manage the oral side effects of irinotecan therapy?

Results confirm long-term success of laser treatment for vocal cord cancer

The first long-term study of a pioneering endoscopic laser treatment for early vocal cord cancer, previously shown to provide optimal voice outcomes, finds that it is as successful as traditional approaches in curing patients' tumors.

Clear excision margins vital for stage Ia1 squamous cervical cancer management

Clear excision margins vital for stage Ia1 squamous cervical cancer management

Women with clear surgical margins after the initial excision are more likely to remain disease-free.

Treatment-related cognitive issues in children with leukemia may have a genetic link

Common variations in four genes related to brain inflammation or cells' response to damage from oxidation may contribute to the problems with memory, learning, and other cognitive functions seen in children treated for acute lymphoblastic leukemia (ALL).

Life expectancy still not used to determine aggressiveness of prostate cancer treatment

More than half of prostate cancer patients age 66 years and older have life expectancies of less than 10 years, yet half of them were over-treated for their prostate cancer with surgery, radiation, or brachytherapy.

Many breast cancer patients do not receive shorter radiation treatment

Although the use of a radiation treatment that is shorter in duration and less costly has increased among women with early stage breast cancer who underwent breast conserving surgery, most patients who meet guidelines to receive this treatment do not.

Quantifying mental disorders in patients with cancer

Quantifying mental disorders in patients with cancer

Researchers in Germany interviewed more than 2,000 patients with cancer to gather epidemiologic data on mental health of patients with cancer.

Gefitinib effective in older, African American patients with non-small cell lung cancer (NSCLC)

Researchers have found that an FDA-approved therapy could be effective in treating both older and African American patients with advanced lung cancer who may not be candidates for chemotherapy.

Organ preservation in kidney cancer more likely at facilities that are early adopters of robotic surgery

Patients with operable kidney cancers were more likely to have a partial nephrectomy, which is the recommended treatment for localized tumors, when treated in hospitals that were early adopters of robotic surgery, according to a new study.

Antacids linked to better survival in patients with head and neck cancer

Patients with head and neck cancer who used antacid medicines to control acid reflux had better overall survival, according to a new study.

Long-term testosterone therapy does not increase risk of prostate cancer

Current evidence seems to indicated that withholding T therapy in hypogonadal men cannot be justified.

Mobile support system keeps up with a younger generation of breast cancer survivors

Mobile support system keeps up with a younger generation of breast cancer survivors

A new digital program using a Web site and social media aims to meet the unique support needs of women younger than 40 years with breast cancer.

Initial surgical therapy for advanced-stage laryngeal cancer may increase survival

A single academic center performing a high rate of surgical therapy, including total laryngectomy, to treat advanced-stage laryngeal cancer had a higher 5-year survival rate than national levels in a small study.

Fulvestrant improves survival over anastrozole for patients with advanced breast cancer

Fulvestrant did more to improve survival than anastrozole for patients with advanced, hormone receptor-positive breast cancer, according to data.

Study shows need for psychosocial support for patients undergoing hematopoietic stem cell transplant

Study shows need for psychosocial support for patients undergoing hematopoietic stem cell transplant

According to a recent study, patients undergoing hematopoietic stem cell transplantation (HCT) reported a steep problems and substantially worsening depression during hospitalization.

Breast cancer has different biological characteristics and outcomes in men and women

Results from the largest series of male breast cancer cases ever studied shows improvement in male survival, but not equal to that seen in women with breast cancer.

New imaging system may cut radiation exposure for liver cancer patients

An interventional x-ray guidance device approved by the U.S. Food and Drug Administration in 2013 may have the potential to reduce the radiation exposure of patients undergoing intra-arterial therapy for liver cancer.

Adding ultrasound to routine mammography improves cancer detection in dense breasts

Among women with denser breasts, an additional ultrasound can detect breast cancers not discovered by mammogram.

Multigene test can predict risk of recurrence for women with ductal carcinoma in situ

A multigene test was validated as a predictor of risk of disease recurrence among women treated with breast-conserving surgery alone for ductal carcinoma in situ (DCIS), according to data from a large study.

Guanfacine may help with smoking cessation

Guanfacine may help with smoking cessation

Guanfacine, a medication used to treat hypertension, shows promise as a smoking cessation aid.

Capecitabine does not improve survival in elderly patients with early stage breast cancer

In elderly patients with moderate- to high-risk early stage breast cancer for whom standard chemotherapy is too toxic, capecitabine did not improve outcomes when tested as monotherapy, according to recent data.

Key discovery in understanding successes and failures of immunotherapy

Key discovery in understanding successes and failures of immunotherapy

A key discovery has advanced the understanding of why some patients respond to ipilimumab, an immunotherapy drug, whereas others show less response.

Galeterone active in one form of castration-resistant prostate cancer

The anticancer drug galeterone has proved successful in lowering prostate-specific antigen levels in men with castration-resistant prostate cancer (CRPC).

Researchers identify biological indicator of response to new ovarian cancer drug

A method to determine which patients with ovarian cancer are more likely to respond well to the new anticancer drug rucaparib has been discovered.

Financial incentives double quit rates among smokers

Employing financial incentives to encourage smokers to reduce cigarette use can be a successful ploy.

Women with serious mental illness are less likely to receive cancer screenings

Women with symptoms of serious mental illness are significantly less likely to receive the three routine cancer screenings of Pap tests, mammography, and clinical breast examinations than women in the general population.

Adult survivors of childhood eye cancer experience few cognitive or social setbacks

Adult survivors of retinoblastoma, a type of eye cancer that usually develops in early childhood, are typically free from long-lasting effects, a new study shows.

Ovarian cancer patients may benefit from pelvic radiotherapy

Ovarian clear cell adenocarcinoma (CCA), a rare and aggressive form of ovarian cancer, may be treated by employing pelvic radiotherapy (RT).

Researchers suggest new follow-up model for breast cancer patients

The surveillance and follow-up of breast cancer survivors has the potential to improve, from the perspective of both patients and the health system.

Cognitive behavioral therapy for insomnia benefits cancer survivors

Cognitive behavioral therapy for insomnia benefits cancer survivors

Significant and durable improvements in insomnia and sleep quality, with and without armodafinil

Personalized genetic test predicts recurrence risk for prostate cancer

A genetic test has been developed to identify which men are at higher risk for prostate cancer recurrence after localized treatment with surgery or radiotherapy.

Tumor-analysis technology speeds treatment decisions for colorectal cancer

A novel medical-imaging technology, TexRAD, which analyzes the texture of tumors, has been shown in trials to enable early diagnosis of colorectal cancer in patients not responding to the standard cancer therapy better than other available tumor markers.

Conventional therapies are less effective in prostate cancer with BRCA mutations

Prostate cancer patients with hereditary mutations in the BRCA genes do not respond as well to conventional treatment such as surgery and radiotherapy, and they have a lower survival rate than patients who do not have these genetic mutations.

Chemotherapy after radiation slows progression of low-grade gliomas

A chemotherapy regimen of procarbazine, lomustine (CCNU), and vincristine (PCV) administered after radiation therapy improved both progression-free survival and overall survival in adults with low-grade gliomas.

Cancer-killing virus and doxorubicin act synergistically on metastatic ovarian cancer

Cancer-killing virus and doxorubicin act synergistically on metastatic ovarian cancer

A new approach to treatment using a cancer-killing virus combined with a chemotherapy drug may offer hope to those with advanced and recurrent forms of metastatic ovarian cancer.

Can consensus guidelines defining adequate margins decrease unnecessary breast cancer surgeries?

Nearly one quarter of all women who underwent initial breast conservation surgery (BCS) for breast cancer had a subsequent surgical intervention.

FOLFIRI treatment response not related to colorectal cancer classification by gene expression

The current classification system for colorectal cancer, based on genetic profiles, cannot be used to predict drug responses to FOLFIRI.

First targeted treatment to boost survival for esophageal cancer

Patients with a specific type of esophageal cancer survived longer when they were given the latest lung cancer drug, according to trial results.

Exercise therapy benefits breast cancer survivors

Exercise offers several benefits for breast cancer survivors, including reduced symptoms of lymphedema, according to a new study.

Navigation and survivorship: Rationalizing your program costs

Navigation and survivorship: Rationalizing your program costs

The cost of nonbillable nursing hours needed for these programs may hinder compliance. The right technology can link treatment silos and lower this cost.

Improved survival in pediatric umbilical cord transplants for hematologic cancers

Improved survival in pediatric umbilical cord transplants for hematologic cancers

A new standard of care for children facing acute myeloid leukemia (AML) may be clear, following a multiyear study.

Radiation exposure linked to aggressive thyroid cancers

For the first time, researchers have found that exposure to radioactive iodine is associated with more aggressive forms of thyroid cancer, according to a careful study of over a thousand individuals.

Monitoring psychosocial function in radiotherapy

Monitoring psychosocial function in radiotherapy

Psychosocial decline occurs in an estimated one-third of patients undergoing radiotherapy for cancer. These declines may sometimes be ameliorated by vigilant recognition of the need to refer patients for psychosocial support interventions.

Variation seen in number of cancer survivors undergoing HIV testing

Variation seen in number of cancer survivors undergoing HIV testing

Proportion undergoing testing varies by demographic and health-related factors, and by state, a study found.

Postoperative radiation therapy improves overall survival in resected NSCLC

Patients with non-small lung cancer (NSCLC) that received postoperative radiation therapy (PORT) lived an average of 4 months longer, when compared with patients who had the same disease progression and treatment criteria.

Stereotactic body radiotherapy (SBRT) effective for inoperable early stage lung cancer

Excellent long-term, local control for medically inoperable, early stage lung cancer patients is possible, according to a review of data from an institutional patient registry on stereotactic body radiotherapy (SBRT).

AHA: Even with weight gain, smoking cessation ups survival

AHA: Even with weight gain, smoking cessation ups survival

Research indicates smoking cessation boosts survival, even if there has been a weight gain.

Combination treatment for metastatic melanoma results in longer overall survival

Treatment with a combination of the drugs sargramostim plus ipilimumab, rather than ipilimumab alone, yielded longer overall survival and lower toxicity for patients with metastatic melanoma.

Cellular evidence for mind-body connection in breast cancer survivors

Researchers have demonstrated that employing mindfulness meditation or being a member of a support group has a positive physical impact at the cellular level in breast cancer survivors.

Risk prediction improved by new classification in chronic lymphocytic leukemia

Risk prediction improved by new classification in chronic lymphocytic leukemia

A new correlation discovered between specific molecular disease features and subgroups of patients with different prognoses could make identification of chronic lymphocytic leukemia (CLL) prognosis at the time of diagnosis possible.

Quality of biopsy directly linked to survival in patients with bladder cancer

Researchers have demonstrated for the first time that the quality level of diagnostic staging using biopsy in patients with bladder cancer is directly linked with their survival.

Resection for lung cancer in the elderly: Lobectomy better than sublobar resection

Resection for lung cancer in the elderly: Lobectomy better than sublobar resection

Significant advances have been made in screening for lung cancer and in targeting those patients who will benefit most from it. This study examines the impact of screening and treatment modalities on elderly patients.

Postsurgery readmission rates questioned as a quality measure in colorectal cancer care

Hospital readmission rates after colorectal cancer surgery showed little variation when the data was adjusted to account for patient characteristics, coexisting illnesses, and operation types.

ONA Interview: Breaking the barriers to effective palliative care

ONA Interview: Breaking the barriers to effective palliative care

Oncology Nurse Advisor talked with Diane Meier, MD, about the components of quality palliative care. Dr. Meier is director of the Center to Advance Palliative Care and vice-chair for Public Policy and a professor at Icahn School of Medicine at Mount Sinai in New York City; she is also the co-author of a new book on palliative care.

Breast cancer tumor response to neoadjuvant chemotherapy (NAC) measured

Diffuse optical spectroscopic tomographic imaging (DOST) may be useful in predicting which patients will best respond to chemotherapy used to reduce breast cancer tumors before surgery, according to a new study.

Early palliative care can cut hospital readmissions for cancer patients

A new, collaborative model in cancer care aims to reduce the rates at which patients go to intensive care or are readmitted to the hospital after discharge.

Chest radiation to treat childhood Wilms tumor increases breast cancer risk

A new study has found that patients who received chest radiation for Wilms tumor may be more susceptible to breast cancer later in life, due to their radiation exposure.

Trastuzumab shows benefit years after treatment for HER2+ breast cancer

The addition of trastuzumab to chemotherapy significantly improved the overall and disease-free survival of women with early stage HER2-positive breast cancer.

Innovative program helps combat catheter-associated urinary tract infections (CAUTI)

Innovative program helps combat catheter-associated urinary tract infections (CAUTI)

Oncology nurses at a New York cancer center successfully reduced the rate of CAUTIs at their facility to zero with a novel program that gives nurses autonomy in making care decisions for patients with urinary catheters.

Survival comparable after radiation therapy for tumors in left or right breast

Location of a breast cancer tumor, on the left or right side, does not impact overall survival in patients treated with breast-conserving surgery and adjuvant external beam radiation therapy.

3-D printed facial prosthesis offers new hope for eye cancer patients after surgery

By utilizing both facial scanning software and 3-D printing, researchers have developed an inexpensive way to make facial prostheses for patients with eye cancer.

Telephone counseling sessions increase likelihood that childhood cancer survivors receive cardiac screening

Telephone counseling sessions increase likelihood that childhood cancer survivors receive cardiac screening

Written heart screening guidelines plus telephone counseling doubled the probability of childhood cancer patients receiving cardiac monitoring.

Treatments and survival benefits compared for early stage lung cancer

Removal of an entire lung lobe may offer patients with early stage lung cancer better overall survival compared with a partial resection.

Cancer prehabilitation: One step toward improved outcomes

Cancer prehabilitation: One step toward improved outcomes

As cancer care evolves toward anticipatory rather than reactionary care, oncology nurses should consider developing important new skills.

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