Fertility preservation research project seeks to serve young boys with cancer

Young men who have a high risk of becoming sterile the option to bank a small piece of testicular tissue prior to cancer treatment.

Poor staging linked to mortality in bladder cancer

Poor staging linked to mortality in bladder cancer

In cases of bladder cancer, omission of muscle in specimen or its mention in pathology report is linked to increased mortality.

Dramatic response and resistance to cancer drug traced to unsuspected mutations

Examination of the DNA of a thyroid cancer survivor has revealed details about resistance to the drug everolimus, according to researchers.

New treatment for retinoblastoma expected to save more eyes from cancer

A new technique to treat retinoblastoma may help prevent eye loss, blindness, or death in children with advanced forms of the disease.

Achieving clinical trial participation through cooperative networks

Achieving clinical trial participation through cooperative networks

Clinical trials could benefit from a greater number of participants with a dedicated cooperative network to support rural community cancer centers.

Lung cancer can stay hidden for 20+ years

Lung cancer can remain dormant in the body for many years before emerging in an aggressive form, according to new research.

Improved tyrosine kinase inhibitor (TKI) selectively activates in tumor tissue, minimizing side effects in patients

A new strategy developed by an interdisciplinary team of researchers aims to reduce the side effects connected to use of tyrosine kinase inhibitors (TKIs).

Immunotherapy added to radiotherapy may help overcome resistance to treatments

Immunotherapy added to radiotherapy may help overcome resistance to treatments

Coupling immunotherapy to radiotherapy treatment could help prevent cancers from becoming resistant to treatment, according to a new study.

Current therapy for hypothyroidism endorsed by new guidelines

A recent review has found insufficient consistent data exist to recommend a change in use of levothyroxine as the only drug needed to treat hypothyroidism.

Importance of sequence in chemotherapy administration

Importance of sequence in chemotherapy administration

Is sequencing important when administering chemotherapy on the same day?

Nearly 5 percent of cancer patients die a month after surgery

Nearly 5 percent of cancer patients die a month after surgery

In a study of more than 1.1 million cancer patients who had surgery, almost 5 percent died within one month of their operation. Lack of access to quality care a major factor in these deaths, researchers say.

High-dose radiotherapy doesn't offer survival benefit in mesothelioma

Treatnent with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to phase II trial data.

Cediranib added to chemotherapy improves progression-free survival in cervical cancer

Addition of the experimental drug cediranib to standard chemotherapy improves tumor shrinkage and adds a modest improvement in progression-free survival for patients with cervical cancer that has recurred after treatment.

Afatinib improves progression-free survival in head and neck cancer

After failure of platinum-based chemotherapy, the tyrosine kinase inhibitor (TKI) afatinib significantly improved progression-free survival in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.

Using guideline adherence to manage CINV effectively

Using guideline adherence to manage CINV effectively

Guidelines for managing chemotherapy-induced nausea and vomiting direct management toward risk assessment and prophylactic antiemetics.

Elevated cholesterol associated with prostate cancer recurrence

Elevated cholesterol associated with prostate cancer recurrence

Findings suggest that elevated levels of cholesterol and triglycerides may be linked with greater risk of the prostate cancer recurrence, but normalization of blood fats may reduce risk.

HER2 inhibition shows promise in HER2-positive non-small cell lung cancer

Human epidermal growth factor receptor 2 (HER2) mutations may offer an important treatment target in a subset of patients with non-small cell lung cancer.

Good news for young patients with a leukemia subtype with poor prognosis

Good news for young patients with a leukemia subtype with poor prognosis

For younger patients with an acute lymphoblastic leukemia (ALL) subtype, modifying treatment based on chemotherapy response can make a vital difference.

Good bowel cleansing key for high-quality colonoscopy

Successful colonoscopy is closely dependent on good bowel preparation, and poor bowel prep often leads to missed precancerous lesions.

An episode of sudden-onset jaundice signaled pancreatic cancer in a healthy man

An episode of sudden-onset jaundice signaled pancreatic cancer in a healthy man

After surviving pancreatic cancer, a patient learns the disease metastasized to his liver. But this patient was not ready to give up. With the support of a liver surgeon, he underwent surgery and beat his disease.

E-cigarettes not helpful in smoking cessation among cancer patients

E-cigarettes not helpful in smoking cessation among cancer patients

Smokers with cancer using e-cigarettes (in addition to traditional cigarettes) were found to be more nicotine dependent and equally or less likely to have quit smoking traditional cigarettes than nonusers.

Combination treatment for melanoma achieves significant progression-free survival and response rates

Combination therapy with both BRAF inhibitor vemurafenib and MEK inhibitor cobimetinib achieved superior results over vemurafenib plus placebo for BRAF-mutation positive melanoma.

Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study confirms use of trastuzumab for HER2-positive breast cancer

The use of trastuzumab (Herceptin) as the standard-of-care treatment for HER2-positive breast cancer has been supported by the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study.

Tool successfully distinguishes between breast cancer and normal tissues

Researchers have successfully tested a new tool that will help surgeons better distinguish cancerous breast tissue from normal tissue, which should lower the mount of repeat procedures needed.

Targeted combination therapy halts disease and extends life in advanced melanoma

A targeted combination drug therapy has shown efficacy for metastatic melanoma, showing reduction in both mortality and disease progression.

New antifungal is as effective as existing drugs and with fewer adverse events

A newly developed antifungal has proved as effective against invasive mold disease in cancer patients as the standardly used drug, voriconazole, with fewer side effects.

Ortho-oncology team achieves successful hip articulation by repurposing a shoulder surgical aid

A shoulder surgical aid, known as the Spider Limb Positioner, was adapted successfully to conduct a left hip disarticulation on a patient with melanoma.

Improved survival for inoperative liver cancer through a combined therapy

Patients that have inoperable advanced hepatocellular carcinoma (HCC) may live significantly longer by receiving a combined therapy, according to recent trial results.

Once-weekly breast radiation regimen improves on current treatment

An experimental regimen of once-weekly breast irradiation after lumpectomy provides more convenience to patients at less expense, and results in better completion rates of prescribed radiation treatment.

ESMO: Combination treatments increase metastatic melanoma survival

ESMO: Combination treatments increase metastatic melanoma survival

Studies show improved progression-free melanoma survival for both cobimetinib combined with vemurafenib, and dabrafenib combined with trametinib.

Prostate cancer treatment controversy continues as study finds watchful waiting not enough for some men

An active controversy among oncologists concerns watchful waiting versus more active treatment for prostate cancer.

Concurrent radiation and chemotherapy after surgery effective in high-risk endometrial cancer

Radiation therapy with concurrent paclitaxel chemotherapy after surgery can be effective to treat patients with high-risk endometrial cancer, according to new research.

Evidence-based design: A new concept in health care facilities that puts the focus on patients

Evidence-based design: A new concept in health care facilities that puts the focus on patients

A medical center in New Jersey makes the most of a rare opportunity to rebuild from the ground up. Its innovative patient rooms follow evidence-based design, a new concept in health care architecture.

Olaparib tablet safe in patients with ovarian cancer who received pretreatment

A PARP inhibitor in oral tablet form, given in combination with chemotherapy, was deemed safe for heavily pretreated patients with ovarian cancer.

E-cigarettes don't help cancer patients stop smoking

E-cigarettes don't help cancer patients stop smoking

Smokers with cancer who used e-cigarettes along with traditional cigarettes were more dependent on nicotine, and the long-term safety of the devices still unclear, researchers caution.

Indeterminate melanoma cases reduced by three-quarters by diagnostic test

Malignant melanoma was differentiated from benign skin lesions with high accuracy in a pivotal clinical utility study of the Myriad myPath Melanoma test.

For cancer patients, e-cigarettes not helpful for smoking cessation

For cancer patients, e-cigarettes not helpful for smoking cessation

Patients with cancer who use e-cigarettes as a form of smoking cessation are equally or less likely to quit smoking.

AACR: Targeted drugs and prevention reduce cancer mortality

AACR: Targeted drugs and prevention reduce cancer mortality

About 14.5 million U.S. cancer survivors are alive today, but aging population and increasing obesity threaten progress.

Better classifications improve treatment planning for breast cancer

Scientists have developed a tool to distinguish each breast cancer subtype, research that could improve treatments and targeting of treatments for the disease.

ASTRO: Prostate cancer recovery faster with less androgen deprivation therapy

ASTRO: Prostate cancer recovery faster with less androgen deprivation therapy

Shorter time to testosterone recovery with 18 versus 36 months androgen deprivation therapy.

Tumor cells prep lymphatic cells to encourage breast cancer cells to spread

Breast cancer cells can lay the groundwork for their own metastasis throughout the body by coaxing cells within lymphatic vessels to send out tumor-welcoming signals.

Protein deletion predicts length of progression free survival (PFS) in patients with non-small cell lung cancer (NSCLC)

Deletion of the Bcl-2-like protein 11 (BIM) in advanced non-small cell lung cancer has been associated with shorter progression free survival (PFS).

Risk of premature menopause after Hodgkin lymphoma treatment is mapped

Women treated for Hodgkin lymphoma will be able to better understand their risks of future infertility after researchers estimated their risk of premature menopause with different treatments.

Patient and tumor characteristics in melanoma examined for clues to aggressive form of disease

Researchers in Australia examined patient and tumor characteristics of melanomas for higher mitotic rates (a marker of tumor cell growth) in an effort to increase early detection.

For black men with prostate cancer, watchful waiting may be unwise

For black men with prostate cancer, watchful waiting may be unwise

For men with early-stage prostate cancer, watching waiting is not always the best course of action, especially for black patients.

Irinotecan promising in some patients with stage III colon cancer

A subset of patients with stage III colon cancer had improved survival rates when treated with irinotecan-based therapy, according to recent research.

Weekend hospitalization linked to longer stays for pediatric patients with leukemia

Weekend hospital admission for pediatric patients with newly diagnosed leukemia is associated with a longer length of stay, slightly longer wait to start chemotherapy, and higher risk for respiratory failure.

Soy may be detrimental for women with breast cancer

Soy may be detrimental for women with breast cancer

Study raises questions about the effect of soy's estrogen-like properties.

Biomarker highly promising for predicting breast cancer outcomes

A protein named p66ShcA shows promise as a biomarker to identify breast cancers with poor prognoses, according to new research.

Opioid-related deaths are almost 25% lower in states with medical marijuana laws

Rates of death resulting from opioid analgesic overdoses are lower in states that allow medical use of marijuana compared with states without such laws.

Surgery associated with better survival for patients with advanced laryngeal cancer

Patients with advanced laryngeal cancer appear to have better survival if they are treated with surgery than with nonsurgical chemoradiation.

Natural killer cells battle pediatric leukemia

Natural killer cells battle pediatric leukemia

A select team of immune-system cells from patients with leukemia can be multiplied in the laboratory, creating a horde of natural killer cells that can be used to target and destroy the cancer cells.

Factors associated with late hospice admission for cancer patients identified

Factors associated with late hospice admission for cancer patients identified

For patients with cancer, late admission more likely for younger patients, married men, hematologic malignancies.

Promising results from trial for late-stage peritoneal cancers

A drug originally used to treat ovarian cancer has shown promising results in patients with advanced peritoneal cancers during a phase I clinical trial.

New analyses of epigenetics reveal tumor weaknesses

Scientists have known for decades that cancer can be caused by genetic mutations, but more recently they have discovered that chemical modifications of a gene can also contribute to cancer.

Major breakthrough in understanding acute lymphoblastic leukemia

Major breakthrough in understanding acute lymphoblastic leukemia

By analyzing the DNA sequence of patients at different stages of leukemia, researchers have discovered mutations in genes that lead to childhood leukemia of the acute lymphoblastic type, the most common childhood cancer.

Less radical procedures control kidney cancer similarly to surgery

Needle-guided tumor destruction procedures offer near equivalent lengths of cancer control when compared with surgery for patients with small kidney cancer tumors.

Now what? Aiding patients in planning for cancer survival

Now what? Aiding patients in planning for cancer survival

The transition to a primary care provider after completing cancer treatment should begin with a plan that documents treatments and follow-up care.

Gene likely to promote childhood cancers pinpointed

Researchers have identified a gene that contributes to the development of several childhood cancers, research that could lead to new strategies for targeting certain childhood cancers at a molecular level.

Postmenopausal breast cancer risk drops off after starting regular physical activity

Postmenopausal women who in the past 4 years had undertaken regular physical activity equivalent to at least 4 hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less

Chemoprotective effects of coffee

Chemoprotective effects of coffee

Diet and nutrition are significant factors in preventing hepatic diseases progressing to hepatocellular carcinoma, and coffee is high on the list of good foods.

Lung cancer rates declining but vary by subtype, sex, race/ethnicity, and age

A new analysis confirms that US lung cancer rates are declining overall, but it also uncovers previously unrecognized trends related to cancer subtype, sex, race/ethnicity, and age.

Expressive writing improves health outcomes for breast cancer survivors

Writing down fears, emotions, and the benefits of a cancer diagnosis may improve health outcomes for Asian American survivors of breast cancer, according to a new study. The research investigated methods of reducing the psychological burden among minority patients, particularly among breast cancer survivors.

Molecular panel increases likelihood that initial surgery for thyroid cancer is corrective

Routine use of a molecular testing panel greatly decreased the need for an initial lobectomy to confirm diagnosis in patients with thyroid nodules and cancer, reported researchers. The test improved the chances of patients undergoing the correct initial surgery by 30%.

Childhood cancer survivors do not eat healthier than their peers

Childhood cancer survivors do not eat healthier than their peers

Having survived cancer as a child does not necessarily have a ripple effect.

Single-fraction radiation therapy (SFRT) as effective as multiple-fraction (MFRT) for palliating bone metastases

Standardizing prescribing practices for single-fraction radiation therapy (SFRT) for palliation of bone metastases could lead to cost savings and improvement in patients' quality of life, according to a new study.

Protein is predictive of treatment that makes radiotherapy for bladder cancer more effective

Scientists have identified a protein that could help doctors decide which patients with bladder cancer would benefit from a treatment that makes radiotherapy more effective, according to a new study.

Drug target identified for common childhood blood cancer

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers report that they have identified a possible new drug target for treating the disease.

Computer tomography (CT) lung screening benefits far outweigh patient anxiety

Anxiety regarding inconclusive cancer screening test results among some patients is real and is only natural. However, as evidenced by a recent study, the incidence and effects of anxiety associated with false positive or other results of CT lung cancer screening exams are far less than claimed by some in the medical community.

Unhealthy habits double metabolic syndrome risk for childhood cancer survivors

By failing to follow a heart-healthy lifestyle, 73% of adult survivors of childhood cancer more than doubled their risk of developing metabolic syndrome and related health problems, according to a new study.

Lasting drop in prostate cancer mortality with prostate-specific antigen (PSA)

Lasting drop in prostate cancer mortality with prostate-specific antigen (PSA)

Prostate-specific antigen (PSA) screening is associated with a lasting reduction in prostate cancer mortality, according to a study published online.

Genomic analysis of prostate cancer suggests best plan after surgery

Genomic analysis of prostate cancer suggests best plan after surgery

A genomic tool can help doctors and patients make a more informed decision on the need for radiation therapy after surgery for prostate cancer.

Survival better with surgical resection than with endoscopic resection for early esophageal cancer

A study sheds new light on the risks associated with the growing popularity of endoscopic resection in the treatment of localized, early stage esophageal cancer. Researchers found that the more traditional surgical resection, while more invasive, provided significantly better outcomes for patients than endoscopic resection.

Saltier IV reduces complications from Whipple surgery for pancreatic cancer

Adequate hydration via a saline drip is essential during surgery, but recent reports suggest that getting the balance of salt and water just right could have an important impact on patient recovery.

Recent use of some birth control pills may increase breast cancer risk

Recent use of some birth control pills may increase breast cancer risk

Women who recently used birth control pills containing high-dose estrogen and a few other formulations had an increased risk for breast cancer, whereas women using some other formulations did not, according to recent data.

Surgical treatment for metastatic melanoma of the liver increases overall survival

Surgical resection markedly improves survival among patients with metastatic melanoma whose disease is isolated to a few areas in the liver, according to new study findings.

Even after cancer diagnosis, 1 in 10 survivors continues to smoke

Even after cancer diagnosis, 1 in 10 survivors continues to smoke

A new study published in the journal Cancer Epidemiology, Biomarkers, & Prevention found that nearly 1 in 10 cancer survivors continued smoking despite their cancer diagnosis

Robot-assisted surgery for prostate cancer controls disease for 10 years

Robot-assisted surgery to remove cancerous prostate glands is effective in controlling the disease for 10 years, according to a new study.

Healthy lifestyle reduces metabolic syndrome risk for cancer survivors

Healthy lifestyle reduces metabolic syndrome risk for cancer survivors

Reduced risk of metabolic syndrome (MetS) has been observed in male and female childhood cancer survivors who adhere to WCRF/AICR guidelines.

Shingles vaccine found to be safe and effective after chemotherapy

Shingles vaccine found to be safe and effective after chemotherapy

The herpes zoster vaccine continues to be effective in protecting older adults against shingles, even after they undergo chemotherapy, according to a recent study.

Rehabilitation benefits advanced cancer patients

Patients with advanced cancer can benefit from a rehabilitation program combining exercise, nutritional counselling, and symptom control, according to an evidence review.

Navigators can help guide patients with breast cancer through care

Navigators can help guide patients with breast cancer through care

A team of researchers from Boston University School of Medicine sought to determine the impact of patient navigators on the care of low-income and African-American women with breast cancer.

Electroacupuncture improves quality of life for breast cancer patients using AIs

Electroacupuncture improves quality of life for breast cancer patients using AIs

Use of electroacupuncture produces significant improvements in fatigue, anxiety, and depression in as little as 8 weeks for patients with early stage breast cancer patients experiencing joint pain related to the use of AIs to treat breast cancer.

Overall survival in advanced NSCLC increased with less toxic chemotherapy

A 10-year study shows that increased availability of better systemic chemotherapies and targeted therapies for patients with advanced non-small cell lung cancer coincides with increased usage of these therapies.

Repeat colonoscopies not always beneficial for some patients

Repeat colonoscopies not always beneficial for some patients

Little benefit seen for repeat colonoscopy within 10 years in patients with no polyps on initial exam.

Research team makes cancer glow to improve surgical outcomes

Research team makes cancer glow to improve surgical outcomes

Surgical resection is the most effective method for a cancer cure; however, the procedure may not remove the entire tumor, leading to local recurrence. Researchers at the University of Pennsylvania have established a new strategy in which near-infrared (NIR) imaging is used to help visualize the entire tumor.

Survival equivalent with cetuximab or bevacizumab in metastatic colorectal cancer

For patients with KRAS wild-type untreated colorectal cancer, adding cetuximab or bevacizumab to combination chemotherapy offers equivalent survival.

Study compares treatment risks for early esophageal cancer

Study compares treatment risks for early esophageal cancer

A new study sheds new light on the risks associated with the growing popularity of endoscopic resection in the treatment of localized, early-stage esophageal cancer.

Fewer cardiac scans in low-risk childhood cancer survivors can safely reduce costs

A less frequent screening schedule would both reduce health care charges and still protect low-risk childhood cancer survivors from heart ailments caused by drug therapy, according to recently published findings.

Everolimus does not improve overall survival of advanced liver cancer

Despite strong preclinical data, the drug everolimus failed to improve overall survival in patients with advanced liver cancer, compared to placebo, according to a study.

A review of radiotherapy-induced hypopituitarism

A review of radiotherapy-induced hypopituitarism

Some patients undergoing radiotherapy for cancers of the head, neck, and brain are at risk for endocrinopathies. This article reviews the risks, detection, and management of radiotherapy-induced hypopituitarism.

Lifestyle choices may lower metabolic syndrome risk of for cancer survivors

Lifestyle choices may lower metabolic syndrome risk of for cancer survivors

A study conducted by researchers based at the St. Jude Children's Research Hospital has determined that healthy lifestyle choices can help cancer survivors avoid the metabolic syndrome.

Colorectal cancer survival associated with higher vitamin D levels

Colorectal cancer survival associated with higher vitamin D levels

Colorectal cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a study shows.

Lack of Trust in One's Doctor Affects Health of Emotionally Vulnerable Cancer Patients

Lack of Trust in One's Doctor Affects Health of Emotionally Vulnerable Cancer Patients

Patients' relationship with their doctor and their attachment style may affect their physical and mental well-being, especially during vulnerable times such after a cancer diagnosis, according to a new study.

Exercise And Nutrition Counseling Plus Palliative Care Improves Quality Of Life For Patients With Cancer

Exercise And Nutrition Counseling Plus Palliative Care Improves Quality Of Life For Patients With Cancer

A team of researchers in Canada concludes that combining exercise, nutritional counseling, and symptom control to palliative care from diagnosis helps to improve the quality of life for patients with cancer.

Noninvasive advanced image analysis may improve care for lung cancer patients

Lung cancer patients could receive more precise treatment, and their progress could be better tracked by using a new high-tech method of non-invasive medical imaging analysis, according to a new study.

Rates of observation as prostate cancer management vary

Rates of observation as prostate cancer management vary

Rates of observation as management for low-risk prostate cancer vary widely, and primary ADT is not tied to better survival for men with localized prostate cancer.

Robot-assisted surgery effective in controlling prostate cancer for 10 years

Robot-assisted surgery effective in controlling prostate cancer for 10 years

Results of a new study show that robot-assisted surgery to remove cancerous prostate glands is effective in controlling the disease for 10 years.

Managing follicular lymphoma

Managing follicular lymphoma

Changes in how follicular lymphoma is managed have led to substantial improvement in prognosis and over all survival for patients with the disease.

New drug active against most aggressive type of lung cancer

Scientists have shown that a new drug could prove useful in treating small cell lung cancer, the most aggressive form of lung cancer.

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