Genetic mutations in the REST gene have been shown to cause Wilms tumor, a rare kidney cancer that occurs in children. The findings identified mutations in the REST gene in 16 children with Wilms tumor.
Incurable astrocytomas grow into healthy brain tissue like mycelium. Therefore, these tumors cannot be completely removed by surgery and invariably start growing again at some point despite intensive treatment.
Among more than 1500 adults who underwent cardiac surgery, those who were divorced, separated, or widowed were more likely to have died or develop a new functional disability after the surgery compared with the married participants.
Dietary habits have a profound impact on cancer survivorship. A recent study found that unfortunately many survivors do not adhere to healthy dietary guidelines, and those who smoke are even less likely to follow the guidelines.
Patients undergoing oncologic liver surgeries who participated in an enhanced recovery program returned sooner to their normal life function and to adjuvant cancer therapies than patients who were treated with a traditional approach to perioperative care.
Elderly cancer survivors with high self-efficacy for performing strength and endurance exercise may benefit from home-based lifestyle counseling.
Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center sought to assess the effects of treatment for brain tumors in children over 10 years of follow-up.
Patients with melanoma who undergo surgical resection of abdominal metastases live more than twice as long as those treated with drug therapy alone, according to novel research presented at the American College of Surgeons Clinical Congress 2015.
Surviving neuroblastoma as a child can come with just as many challenges as the cancer itself. But a team of surgeons is in the nascent stages of developing a more targeted method for delivering chemotherapy, with lower toxicity.
Findings based on small study of childhood cancer survivors with treatment-related deficits shows benefits of computerized cognitive intervention.
The genetic makeup of colon cancer tumors and survival rates for patients with the disease differ by race, according to a study from the Mayo Clinic Cancer Center in Rochester, Minnesota.
Despite advances in treatment, finding smaller tumors has been linked to better survival results.
Ethnic, racial, and socioeconomic disparities appear to exist among children with retinoblastoma, a once uniformly fatal but now treatable eye cancer. Those disparities are associated with greater risks for advanced disease and undergoing removal of the eye.
Patients successfully treated at age 15 to 39 are nearly 60 percent more likely to develop another cancer, necessitating continued screening.
Aspirin improves survival in patients with tumors situated throughout the gastrointestinal (GI) tract, according to results from a large study. This is the first time that survival data from patients with tumors in different GI locations have been analyzed at the same time.
An experimental gene therapy essentially doubled the overall survival of patients with recurrent glioblastoma compared with the current standard of care.
Current results from a clinical trial comparing a combination of two targeted therapies with a single-agent treatment for advanced melanoma has shown patients are living significantly longer with the combination therapy.
Nonsmokers more likely than smokers to be women and to have adenocarcinoma
Despite growing popularity of patient navigation (PN) in cancer care, few studies have evaluated the impact of PN on patient outcomes.
Adult survivors of childhood brain tumors have lower working memory performance compared with healthy adults, according to research from Georgia State University and Emory University, in Atlanta.
Patients with metastatic nonsquamous non-small-cell lung cancer treated with nivolumab demonstrated greater survival.
In the study, management was changed in 44% more cases by Use of the imaging agent Ga-68 PSMA with PET/CT resulted in a change in management of prostate cancer in 44% more cases than with another widely used agent.
A study of the risk of acute leukemia that considered all 2,760 cases of leukemia in children younger than 15 years in metropolitan France between 2002 and 2007 found that the incidence of myeloblastic leukemia was 30% higher among children who lived within 150 m of heavily used roads.
This fact sheet explores the harmful effects of tobacco smoke, tobacco addiction, and the immediate and long-term benefits of smoking cessation.
The U.S. Preventive Services Task Force (USPSTF) urges PCPs to offer interventions to help adults, including pregnant women, stop smoking.
A new study reveals that insurance status, marital status, and county-level income may affect survival for younger patients with AML, indicating that efforts are needed to address social factors that impact critical aspects of health.
Use of irreversible electroporation (IRE) doubles survival time for patients with locally advanced pancreatic cancer.
Guidelines and novel approaches are helping clinicians to more effectively manage this debilitating side effect of radiation treatment for cancer.
Increased risk of childhood leukemia and lymphoma has been observed with indoor insecticide exposure.
Survivors of childhood cancer have a high risk for stroke at a surprisingly young age.
For children with high-grade gliomas, the chances of survival are improved when surgery is successful in eliminating all visible cancer.
Clinically meaningful weight loss over two years in overweight/obese survivors of breast cancer can be achieved via weight loss intervention.
Genetic mutations identified during remission of leukemia may help predict risk of relapse, survival
Even though potentially curative therapy is now available for many patients with AML, the therapy is expensive and is associated with significant side effects. This study explained that identifying patients at high risk for relapse would be helpful clinically.
Adjuvant chemotherapy does not improve QOL, recurrence, and survival in patients with stage II colon cancer
The American Cancer Society (ACS) has released its second in a series of cancer survivorship care guidelines.
Chemotherapy prolongs life for older adults with most types of cancer, but for women older than 80 years with breast cancer, the chances of improved survival due to chemotherapy are significantly lower, according to a recent study.
A new set of genes has been identified that can indicate improved survival after surgery for patients with pancreatic cancer. The study also showed that detection of circulating tumor DNA in the blood could provide an early indication of tumor recurrence.
What would be the ideal TSH level for patients after total thyroidectomy for cancer of the papillary thyroid?
Some drugs normally taken to treat heart ailments may also be beneficial for ovarian cancer.
Shutting down the healing action of certain white blood cells triggered by chemotherapy may help prevent the spread of cancer.
A combination therapy increased survival rates for individuals with newly diagnosed metastatic, hormone-sensitive prostate cancer.
Many patients with lung cancer do wish to be offered support to help them quit smoking after surgery, according to a recent study.
Researchers have discovered that determining a tumor's medulloblastoma subgroup can be achieved noninvasively, using magnetic resonance spectroscopy (MRS).
Circulating tumor DNA analysis spots stray cells months before scans detect breast cancer recurrence.
Study uses dog sledding to demonstrate benefits of adapted physical activities for children with cancer
The results of a new preliminary study indicate that children with cancer may benefit from a different kind of treatment: a healthy dose of adventure.
The addition of omega-3 fatty acids to antitumor medications may improve treatment response and improve quality of life for cancer patients.
An international team has decoded the molecular characteristics of acute lymphoblastic leukemia (ALL), a cancer with some incurable subtypes.
A genetic variation in the FOPNL gene can increase mortality for patients with multiple myeloma.
Increased risk for treatment-related subsequent neoplasms extends beyond age 40 years.
The effect of irradiation of regional nodes in patients with stage I, II, or III breast cancer on overall survival is very limited, according to a study.
Studies find aromatase inhibitors (AIs) and bisphosphonates improve survival in postmenopausal breast cancer patients
Two new studies suggest that two different classes of drugs, aromatase inhibitors (AIs) and bisphosphonates, can each improve survival prospects for postmenopausal women with early breast cancer.
Greatly improved outcomes have been observed in using stem cell transplantation to treat patients with juvenile myelomonocytic leukemia (JMML), a rare form of blood cancer.
Predictors for long-term survival include younger age, early stage, low grade, non-serous histology
New study strengthens the case that some adolescents and young adults with cancer may struggle in later adulthood with brain and emotional function.
Survivors of childhood cancer remain at increased risk for treatment-related subsequent neoplasms, even after the age of 40.
Despite survival benefits, only 41 percent of suitable candidates actually receive the therapy.
Many breast cancer survivors in Appalachia neglect taking critical follow-up treatment, even though their insurance would cover the cost, a study has found.
A recently compiled database that compares gene expression patterns to survival data could help predict survival outcomes for a variety of cancer types.
Effect of radiotherapy on survival of women with locally excised ductal carcinoma in situ of the breast: a Surveillance, Epidemiology, and End Results population-based analysis
[OncoTargets and Therapy] This research examines the effect of radiotherapy on overall survival in women with locally excised ductal carcinoma in situ (DCIS).
Patients that cease smoking shortly before or after a lung cancer diagnosis experience significant survival benefits.
Despite treatment advances for adolescents and young adults with cancer, they still experience a higher rate of hospitalizations than the general public.
Receptors that mediate activity of the female sex hormones (estrogen and progesterone) interact with DNA to control the growth of a large majority of breast cancers, research indicates.
A new study has examined the unique challenges facing cancer survivors that wish to adopt a child.
Combining two anti-tumor agents appears to increase the sensitivity of cancer cells to these drugs and seems to lead to more effective Ewing's sarcoma treatment.
It is important that patients are advised early about the effect radiotherapy toxicity can have on their sexual anatomy and overall sexual health.
In the first clinical trial of difluoromethylornithine (DFMO), an investigational agent for children suffering from neuroblastoma, side effects were minimal and patients saw long-term survival.
Almost two-thirds of patients with T4a larynx ("voice box") cancer are not receiving a total laryngectomy, despite published guidelines.
Researchers have found that cancer survivors' options for adoption may be limited by adoption agencies' policies.
For patients with radiation-induced xerostomia, ALTENS may reduce symptom burden with less side effects than current standard treatment.
A new study identified several factors that inhibit the efforts of cancer survivors who smoke to quit.
Researchers estimate that 48.5% of the nearly 346,000 deaths from 12 cancers among adults 35 years and older in 2011 were attributable to cigarette smoking, according to a newly published study.
BALTIMORE, MD—For more aggressive cases of non-Hodgkin lymphoma (NHL), posttreatment surveillance with molecular imaging could mean the early start of a new, life-saving treatment. This was presented at the Society of Nuclear Medicine and Molecular Imaging (SNMMI) 2015 Annual Meeting.
The links between demographic, treatment, and socioeconomic factors and breast cancer survival were examined in a recent study.
Women diagnosed with breast cancer and treated with a one-week regimen of partial breast radiation after tumor removal saw no increase in cancer recurrence or difference in cosmetic outcomes.
The first reported case of endoscopic spinal tumor extraction enabled accurate diagnosis and allowed for patient reporting of sensations and motor testing.
Patients with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection of all or part of the lung if combined with chemotherapy and radiation therapy.
The emotional state and health of a cancer survivor's spouse can affect their own well being, a recent study indicates.
Breast surgery performed at or shortly after a diagnosis of low-grade ductal carcinoma in-situ (DCIS) was not found to significantly impact patients' survival rate.
Poor sleep and snoring before breast cancer diagnosis is tied to poor survival outcomes.
Eighty percent of lung cancer deaths linked to smoking, researchers say, and the mortality rate of several other cancers is also strongly impacted by smoking status.
Treating advanced melanoma patients with either a combination of nivolumab and ipilimumab, or nivolumab alone, significantly increases progression-free survival (PFS) when compared with ipilimumab alone.
New templates from the American Society of Clinical Oncology (ASCO) will augment successful cancer survivorship care planning. But a stronger effort toward implementation is still needed.
Long-term childhood cancer survivors have greater prevalence of abnormal global longitudinal strain and diastolic function.
A new study found that prognosis after treatment for women with breast cancer with a family history of the disease is no worse than it is for other women with breast cancer.
Fewer childhood cancer survivors die of 'late effects' from radiation and chemotherapy, according to recent research.
Mesenchymal chondrosarcoma, which often affects young adults, is among the deadliest cancers.
Cancer survivors' information needs differed over time depending on the topic, and these trends varied by cancer type.
Depending on the type of cancer faced, the needs of survivors can vary.
One more potential benefit for breastfed babies, research suggests, is a lowered risk of childhood leukemia.
Modifying pediatric cancer treatments may reduce occurrence of late effects and promoting early detection, indicated data from a 5-year analysis of childhood cancers survivors presented at ASCO 2015.
Government estimates show smoking reduced in roughly half of U.S. states, but some people may be using alternative tobacco products in addition to cigarettes.
Aspirin exposure after a colorectal cancer diagnosis was independently associated with improved colorectal cancer-specific survival.
Higher mortality is associated with more narrow margins for high-risk primary melanoma, per research presented at the American Society of Clinical Oncology (ASCO) 2015 Annual Meeting in Chicago.
As of 2012 in the U.S. there were 14 million cancer survivors, a number that is expected to grow to 18 million by 2022.
Early intervention should be offered to young women with breast cancer on ovarian function suppression and tamoxifen, who experience poorer quality of life (QOL) in the early survivorship period, according to a study presented at the 2015 American Society of Clinical Oncology Annual Meeting.
Cancer treatments in early life can lead to obesity in later years, and counseling and weight loss interventions for certain childhood cancer survivors are important.
No difference seen in distant disease-free intervals for those with versus those without a positive family history, say researchers.
Post-treatment surveillance linked to improved survival in head and neck squamous cell cancer (HNSCC)
Adherence to posttreatment surveillance, income level, and follow-up care proximity had effects on survival in patients with head and neck squamous cell cancer (HNSCC), according to a recent report.
Men with prostate cancer that has spread to nearby lymph nodes may find the addition of radiation therapy to treatments that block the effects of testosterone beneficial.
Combination of docetaxel and hormone therapy can extend life by almost a year for prostate cancer patients, according to new research.
- Risk of Some Cancers Modestly Increased in Persons Who Had Herpes Zoster
- Targeted Treatment Produces Rapid Shrinkage of Recurrent BRAF-mutant Brain Tumor
- Blood Test Indicates Breast Cancer Tumors Developed Resistance to Hormone Treatment
- Breakthrough Advance Announced in International Blood Cancer Drug Trial
- Gut Bacteria Can Dramatically Amplify Cancer Immunotherapy
- Breastfeeding Associated With A Reduced Risk of Aggressive Breast Cancer
- Hospitals Should Enact Bereavement Programs, Researchers Urge
- Physical Activity Communications Should be Part of Oncology Care Clinic Visits With Patients
- Communication Practices of Many US Physicians May Be Discouraging HPV Vaccination
- Navigation Program Tackles Cancer Care on Two Fronts
- Liquid Biopsy of Cerebrospinal Fluid More Effective in Managing Brain Tumors
- Nivolumab Indications Extended to Include Advanced Renal Cell Carcinoma
- S-1 as First-line Chemo for HER2- Metastatic Breast Cancer
- Nanoliposomal Irinotecan Extends Survival in Metastatic Pancreatic Cancer
- Blood Test Identifies Mutations Behind Drug Resistance in Patients Taking Antiandrogen for Prostate Cancer
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