Inheriting certain DNA sequences can affect the prognosis of bladder cancer patients, according to a new study.
Elderly with faster cognitive decline were found to have lower risk of cancer mortality, according to research.
Surgical resection of early-stage pancreatic tumors has the potential to cure patients with this deadly disease but continues to be underutilized, according to a new national analysis.
Mindfulness-based meditation could lessen some symptoms associated with cancer in teens, including depression and sleep quality in girls, according to the results of a preliminary study.
Even months after their child's acute lymphoblastic leukemia diagnosis and treatment, 46% of mothers still exhibited symptoms of clinical anxiety, and 26% of mothers showed depressive symptoms.
Adult survivors of childhood cancer face significant health problems as they age and are five times more likely than their siblings to develop new cancers.
A patient with advanced bladder cancer experienced a complete response to the drug combination everolimus and pazopanib in a phase 1 clinical trial. Genomic profiling revealed information that could help identify other patients who may respond to everolimus and pazopanib.
Shortening the time from first appearance of symptoms to diagnosis has no bearing on survival or stage of disease in unilateral retinoblastoma, the most common form of childhood eye cancer, according to a new study.
Colon cancer incidence rates have dropped 30% in the United States in the last 10 years among adults 50 years and older, the largest decrease in people older than 65 years.
In a study of men with early stage prostate cancer, those who received androgen deprivation as their primary treatment instead of surgery or radiation did not live any longer than those who received no treatment.
Adenoma detection rate is inversely associated with risk of interval colorectal cancer.
For patients with noninvasive urothelial carcinoma, three DNA methylation markers are able to accurately predict tumor recurrence, according to a study.
Women whose breast cancer has spread to just a few axial lymph nodes are less likely to have their disease recur or to die from it if they have radiotherapy after mastectomy.
Genetic analyses of results from postmenopausal women being treated for estrogen-responsive breast cancer have shown that some are more likely to have a late recurrence of their cancer and might benefit from additional years of hormone therapy.
Patients with terminal forms of leukemia and lymphoma who have run out of treatment options could soon benefit from a new drug, which not only puts an end to chemotherapy and has virtually no side effects.
The risk of early relapse is increased when radiotherapy is omitted in patients with stage I/II Hodgkin lymphoma whose PET scan findings are negative, according to an interim trial analysis.
A new approach to breast reconstruction surgery aimed at helping patients' bodies get back to normal more quickly cut their postoperative painkiller use in half and reduced hospital stay, a new study found.
Long-term survivors can enjoy a satisfying meal and good quality of life after esophagectomy with gastric pull-up, according to a new study.
The PROCEDE 500 study demonstrated that 65% of physicians changed their original treatment plans for men with prostate cancer based on results from the Prolaris test.
Biomarkers for the formation and resorption of bone predict outcomes for men with castration-resistant prostate cancer (CRPC).
A new study found substantial long-term reduction in mortality for men with localized prostate cancer who undergo a radical prostatectomy.
Baseline e-cigarette use does not significantly predict quitting smoking one year later or reduce cigarette consumption after one year, according to a study.
The increased risk of a severe, disabling, life-threatening, or fatal health condition persists to age 50 years for many childhood cancer survivors.
Eliminating the protein Mcl-1 could make radiation and chemotherapies more effective in treating the most common and deadly of all cancers, non-small cell lung cancer.
An experimental drug aimed at restoring the immune system's ability to spot and attack cancer halted cancer progression or shrank tumors in patients with advanced melanoma, according to an early-phase clinical trial.
Chemotherapy, one of the major treatments for breast cancer, can leave a long-lasting epigenetic imprint in the DNA of the blood cells of breast cancer patients, according to new research.
For women with gynecologic cancers, treatment at high-volume centers is associated with a survival advantage.
Earlier care improves quality of life and patient satisfaction, according to the results of the first clinical study to assess the impact of providing early outpatient palliative care versus standard oncology care.
For head and neck cancer patients undergoing radiation therapy, a reduction in the amount of radiation treatment volume to the submandibular (level IB) lymph nodes resulted in better patient-reported salivary function.
Adding bevacizumab (Avastin) to standard chemotherapy and radiation treatment does not improve survival for patients with newly diagnosed glioblastoma, an often deadly brain cancer, researchers reported.
Limiting radiation therapy to lymph nodes on one side of the neck for advanced tonsil cancer resulted in good local regional control and no cancer recurrence on the untreated side, according to new research presented at the 2014 Multidisciplinary Head and Neck Cancer Symposium in Scottsdale, Arizona.
Breast cancer patients receiving radiotherapy showed decreased fatigue as a result of cognitive behavioral therapy plus hypnosis, according to a new study.
Avoiding the contralateral submandibular gland during radiation therapy is feasible and safe with advanced stage, node-positive head and neck cancers and base of tongue lesions, according to new research.
Oropharyngeal cancer patients treated with combined chemotherapy and radiation therapy reported a decrease in their voice and speech quality for up to a year after the completion of treatment.
Combining Mutant-Allele Tumor Heterogeneity (MATH) as a biomarker with a patient's HPV status provides an effective indicator of improved patient outcome.
The largest clinical study ever conducted to date of patients with advanced leukemia found that 88% achieved complete remission after being treated with genetically modified versions of their own immune cells.
The most common genetic alteration ever reported in the brain tumor ependymoma has been identified. Researchers also have evidence that the alteration drives tumor development.
A new clinical study has found that erlotinib has promising potential to improve treatment for cervical cancer.
The use of radioimmunotherapy treatment in patients with newly diagnosed follicular lymphoma has been investigated in a new study.
Research has revealed that women with advanced cervical cancer live about 4 months longer with the combined use of bevacizumab and chemotherapy compared with chemotherapy alone.
A new analysis has found that adolescents and young adults who develop thyroid cancer as a secondary cancer have a significantly greater risk of dying than those with primary thyroid cancer.
Assessing the route to cancer on a case-by-case basis might make more sense than basing a patient's cancer treatment on commonly disrupted genes and pathways, according to a new study.
A new analysis confirmed the importance of known prognostic factors such as performance status and tumor grading for having a long-term outcome in patients treated with pazopanib for metastatic soft tissue sarcoma. In addition, hemoglobin at baseline was found to be a new prognostic factor.
Experts have identified three major sources of high cancer costs and argue that cancer doctors can likely reduce them without harm to patients. The cost-cutting proposals call for changes in routine clinical practice involved in end-of-life care, medical imaging, and drug pricing.
For women with breast cancer, incorporating yoga into radiotherapy is associated with a lasting improvement in quality of life.
A panel of 55 genes, almost all of which are impacted by the loss of a particular protein, appears to predict if breast cancer will become invasive.
Acceptable long-term safety, positive therapy responses persist after drug discontinuation
Severe skin reactions during radiation therapy could be prevented by applying a thin transparent silicone dressing to the skin from the first day of treatment, according to clinical research from New Zealand.
An increase in workload increases odds of death, whereas an increase in percentage of nurses with degrees cuts death rates, research found.
Recent articles discussed the need to develop both a learning IT system for cancer that enables real-time data analysis from cancer patients in a variety of care settings.
The American Cancer Society (ACS) has published its latest annual report on cancer incidence and mortality, and the news is good.
Among women with mutations in BRCA1 or BRCA2, oophorectomy reduces the risk of developing ovarian, fallopian tube, or peritoneal cancer by 80 percent.
Men with prostate cancer on active surveillance should be informed of the risk of complications linked to repeated biopsies.
A chemical signature has been found in blood-forming stem cells that predict if a patient with acute myeloid leukemia (AML) will respond to chemotherapy.
Half of African-American men and a third of African-American women will receive a diagnosis of cancer in their lifetimes. The causes of cancer health disparities are complex, stemming from such factors as genetic susceptibility and family history.
Tests that require patients to collect a single stool sample at home and then send it to a lab for analysis will detect about 79% of colorectal cancers. A review of 19 studies examining eight different FITs also finds that the tests will correctly identify about 94% of patients who do not have cancers of the rectum or colon.
Adjuvant bevacizumab increases overall survival in cervical cancer, and two studies show benefits of bevacizumab on PFS in newly diagnosed glioblastoma as well.
Improvements in fatigue, IL-6, TNF-a, and IL-1B seen in a clinical trial that measured the effects of yoga practice in women survivors of breast cancer.
Breast cancer was diagnosed at earlier stages in women age 40 to 49 years who underwent routine screening mammography, and their tumors were less likely to require chemotherapy.
Among patients with advanced melanoma, presence of higher levels of the protein VEGF in blood was associated with poor response to treatment with the immunotherapy ipilimumab.
Positive margins linked to two-fold increased risk of ipsilateral breast tumor recurrence, according to consensus guidelines.
A new type of magnetic resonance imaging (MRI) scan, known as diffusion-weighted MRI, could improve care for myeloma and reduce reliance on bone marrow biopsies.
Health-related quality of life assessment in randomized clinical trials in small cell lung cancer provides added information in studies where the treatment arms do not differ in terms of efficacy.
Long-term outcomes of breast cancer patients receiving adjuvant accelerated partial breast irradiation after breast-conserving surgery show excellent tumor control with minimal late toxicity.
A new report from the American Cancer Society outlines the progress made and challenges that remain in fighting childhood cancer.
When comparing treatments designed to enable long-term breast preservation for older women with invasive breast cancer, researchers found that those treated with brachytherapy were at higher risk for a later mastectomy.
Treating mesothelioma with radiation before surgery resulted in a 3-year survival rate that was more than double compared with that of treating with surgery first, according to new research.
Why do children with Down syndrome who are being treated for acute lymphocytic leukemia sometimes require oral leucovorin after intrathecal methotrexate administration?
Targeted treatments for acute promyelocytic leukemia cause a cascade of molecular events that lead to cellular senescence and recovery. This action model could be activated in other types of cancers.
Researchers found a significantly reduced mortality risk for breast cancer survivors who run.
Combining high-dose interleukin-2 and personalized vaccines to activate patients' immune systems improves survival of metastatic melanoma even more than IL-2 alone.
High pretreatment VEGF levels have been linked to lower survival after ipilimumab treatment.
A new study found that most women who undergo conservative surgery for vulvar cancer experience little to no long-term disruption to sexuality and body image.
Long-term results of an EORTC trial show that 5- fluorouracil (FU)-based adjuvant chemotherapy after preoperative chemoradiotherapy for patients with cT3-resectable T4 M0 rectal cancer does not improve survival or disease-free survival.
Girls treated for Hodgkin's lymphoma during adolescence acquire a considerable risk of developing breast cancer.
Men who walked at a fast pace prior to a prostate cancer diagnosis had more regularly shaped blood vessels in their prostate tumors compared with men who walked slowly, providing a potential explanation for why exercise is linked to improved outcomes.
Twelve-week intervention linked to improved fatigue, vitality, lower levels of proinflammatory cytokines in participants.
Minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer at diagnosis than white patients and those in higher economic brackets.
Many women who are survivors of childhood cancer can become pregnant. This good news comes from the Childhood Cancer Survivor Study, in which nearly two-thirds of the women in the survivor group, initially unsuccessful at becoming pregnant, eventually conceived.
Although challenged, youth with cancer do not have higher rates of posttraumatic stress disorder.
Although complications from surgical care for cancer patients may seem infrequent, the costs associated with such outcomes are extremely high, according to researchers.
Little to no long-term disruption to sexuality or body image for women undergoing treatment for vulvar cancer found, according to a study published online.
Patients with head and neck cancer who are treated with an advanced form of radiation therapy may experience fewer side effects and be less likely to die from their disease than patients who receive standard radiation therapy.
Preventive surgery improves survival for women who are at greater risk of developing ovarian cancer, and it may be helpful for women at risk of developing breast cancer due to genetics.
A protein has been identified that may be a key culprit when breast cancer metastasizes to the brain.
Brisk walking before prostate cancer diagnosis has been associated with more regularly-shaped blood vessels.
A biomarker, adenosine deaminase acting on RNA-1 (ADAR1), has been discovered, and it has the potential to improve the diagnosis, prognosis, and treatment of esophageal squamous cell carcinoma.
Measuring the amount of certain protein fragments and microRNAs in a woman's blood and breast tissue might enable the early diagnosis of breast cancer or prediction of its metastasis.
A higher 90-day mortality was seen after avoidable versus non-avoidable hospitalizations.
A new program designed to increase the overall satisfaction of patients undergoing esophageal surgery has resulted in lower patient costs and reduced times on both the operating table and in the hospital.
A new study demonstrates that nonpharmaceutical techniques can resolve sleep disturbance and insomnia in patients with cancer.
High-dose cytarabine in induction treatment improves the outcomes of adult patients with acute myeloid leukemia (AML).
The methods used to anesthetize patients with prostate cancer and control pain due to surgical resection of the prostate glands for adenocarcinoma may affect patients' long-term cancer outcomes, a study has found.
The leading National Cancer Institute-designated comprehensive cancer centers may not adequately help patients protect their fertility.
Findings among head and neck cancer patients treated with IMRT versus other types of radiation show significant improvements in cause-specific survival.
Cognitive behavioral therapy for insomnia (CBT-I) is the preferred choice over mindfulness-based stress reduction (MBSR) for nonpharmacologic management of insomnia in patients with cancer.
In a study that included more than 800 women who had undergone surgery for breast cancer, the majority reported some level of pain 12 months after surgery.
Women with HER2-positive breast cancer who had the highest levels of immune cells in their tumors gained the most benefit from presurgery treatment with chemotherapy and trastuzumab. These results were presented at the 2013 San Antonio Breast Cancer Symposium.
Combining the chemotherapy drugs docetaxel and carboplatin with the HER2-targeted therapy trastuzumab was identified to be an ideal postsurgery treatment option for patients with HER2-positive breast cancer.
Re-examination of data from four large studies of the benefits and harms of mammography screening shows that the benefits are more consistent across these studies than previously understood.
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