Sarcopenia and adiposity measures may help clinicians steer management strategies for some patients with breast cancer.
Long-term analysis determined the effect of postadjuvant dose-dense chemotherapy on DLCO among women with breast cancer.
A phase 2 study determined if adding bevacizumab or temsirolimus to PC, or an ixabepilone/carboplatin/bevacizumab combination will increase progression-free survival for women with advanced/recurrent endometrial cancer, compared with PC alone.
In a follow-up to the Women's Health Initiative study, researchers determined the effect of a low-fat diet on overall survival after a breast cancer diagnosis.
Researchers report on a study investigating effects of ADT on prostate cancer health-related quality of life, sexual function, sexual bother, and mood for patients with prostate cancer and their partners.
Investigators sought to determine the impact on quality of life for patients with relapsed/refractory multiple myeloma treated with PAN and BTZ+DEX.
Researchers conducted a retrospective cohort analysis to examine patterns of clinical practice in the management of women with advanced HGSC.
Long-term neurotoxicity was more frequently seen with cisplatin than with vinca alkaloids, data indicates.
A link between visual function, ocular symptoms, and quality of life was found in cross-sectional study of patients who underwent radiotherapy for head and neck cancers, according to a presentation at the 2018 ONS Annual Congress.
Study results support the role of androgens and benefits of 5-alpha-reductase inhibition in the progression of bladder cancer.
Patients with lymphoma were interviewed to determine their evaluation of a program that offered continuing clinical care with a nurse-led intervention in the early months of survivorship.
Using a cross-sectional online survey, researchers sought to determine how a MPN diagnosis affects work productivity and employment for patients with polycythemia vera, essential thrombocytopenia, or myelofibrosis.
In this phase 2 study, researchers randomly assigned 79 patients with immunotherapy-naive melanoma with brain metastases to receive either nivolumab plus ipilimumab or nivolumab alone.
A review of SEER data revealed trends in incidence of advanced Hodgkin lymphoma, discrepancies among subgroups, and survival over 3 decades.
Study investigates the risk for cardiovascular events among survivors of endometrial cancer, and the effect of treatment — chemotherapy vs chemotherapy plus radiotherapy — on survivors' risk for CVD.
A review of surveillance mammography demonstrated the potential value of these images in post primary therapy treatment of women with breast cancer.
Using the NEI-VFQ-25, researchers assessed vision-targeted health-related quality of life for survivors of retinoblastoma.
A group of Australian researchers report study findings that demonstrate a significant improvement in PFS in patients with relapsed/refractory CLL treated with venetoclax plus rituximab compared with the standard care.
Researchers evaluated survival in patients with colon cancer, according to the type of insurance the patients held.
Slight changes in taste perceptions are noted in patients undergoing HSCT for hematologic cancers. In this study, researchers sought to determine how these changes affect quality of life and nutritional intake.
A randomized study assessed the effectiveness of an Internet-based psychological intervention in helping women survivors of breast cancer cope with the changes brought by their disease and treatment.
A survey of oncology providers demonstrated a mix of opinions as to whether immunosuppressed children with cancer should attend school.
A report on how variations in the effects of geriatric syndromes and aging can affect treatment modality choices and outcomes for the eldest older adults with hematologic cancers.
A model that incorporates HRQOL was found to outperform a model that only employs traditional prognostic variables.
Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.
Recent research shows that although testicular cancer survivors do not totally conform to the criteria for metabolic syndrome, past treatment with platinum-based chemotherapy increases its prevalence among survivors and may lead to a greater risk for heart disease in this patient population.
A retrospective cohort study of data from the SEER database assessed the potential risk of cardiac-related mortality in patients with breast cancer, treated with chemotherapy or radiotherapy, vs the general population.
Researchers presented the preliminary results from an ongoing randomized, crossover study evaluating the cardiorespiratory effects of e-cigarettes.
In a quasi-experimental pre-post study, researchers demonstrate the efficacy of the SEE-ACBT rehabilitation method on health-related and cost outcomes in patients with NSCLC who underwent curative lung resection.
Researchers reviewed data from a Swiss cancer registry to determine the effects of cancer survivorship on physical and mental health and health-related quality of life experienced by AYA survivors.
Fatigability and poor endurance appeared higher in those with a history of cancer, especially in older adults.
Venetoclax plus rituximab increases progression-free survival in relapsed chronic lymphocytic leukemia
1. Patients with relapsed or remitting chronic lymphocytic leukemia (CLL) treated with venetoclax-rituximab had a greater 2-year progression-free survival rate compared to bendamustine-rituximab treated patients. 2. Progression-free survival rates were greater for venetoclax-rituximab patients in almost all subgroup analysis, including patients with chromosome 17p deletion. Evidence Rating Level: 1 (Excellent) Study Rundown: Curative treatment of relapsed 
Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.
1. Behavioral interventions increase sun protection behavior but do not reduce sunburn or skin cancer outcomes. 2. Behavior interventions lead to increased skin self-examinations but may lead to additional skin procedures without finding additional skin cancers. Evidence Rating Level: 1 (Excellent) Study Rundown: While melanoma comprises 2% of all skin cancers, it causes more than 
Sexual impairment is frequently associated with breast and pelvic cancers, but patients with digestive cancer also experience this effect. In this study, researchers assessed sexual activity, dysfunction, sexual quality of life, and need for oncosexology care among patients with gastrointestinal cancers.
A cross-sectional study asked patients with hematologic cancers to name the components of care they felt were most crucial to their perception of optimal care.
Excretion of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide, crotonaldehyde up
A multivariable analysis revealed how median household income influences cancer-specific and overall survival among patients with squamous cell carcinoma of the anus.
This review of radiodermatitis, a common adverse effect of radiation therapy, discusses preventive and treatment options available that reduce and/or minimize symptoms of the condition.
An analysis of ESAS scores identified factors that increased the odds patients with cancer would experience greater symptom burdens and at what points in the cancer experience this was more likely to occur.
Study finds metals, including lead, leak from e-cigarette heating coils into inhaled aerosols
In this evaluation of palliative care use, investigators were able to determine how the focus of palliative care - coping, treatment, or advanced care planning - influenced patients' decisions on quality of life and decisions regarding chemotherapy and hospice care at the end of life.
Independent of cardiovascular risk factors, a history of cancer is a significant factor in future longevity.
In this study, researchers determined the efficacy of calcitriol, weight-bearing exercise, both, or daily multivitamins on bone formation and resorption in breast cancer survivors actively maintained on hormone therapy.
A retrospective study evaluated the relationship of BMI with survival outcomes among patients with metastatic melanoma who received targeted therapy, immunotherapy, or chemotherapy.
SPARTAN phase 3 study shows that apalutamide prolongs metastasis-free survival and time to symptomatic progression compared with placebo among men with nonmetastatic CRPC.
Researchers evaluated the effect of antibiotics on treatment delays, interruptions, and dose reductions in patients with mRCC treated with a first-line VEGF-TKI and presented their results at the 2018 Genitourinary Cancers Symposium.
Increasing trend seen for some lethal cancers, with up to 5 percent increase for liver, pancreas, lung CAs
Results of a nonblinded study demonstrate the value of incorporating early palliative care into oncologic care for patients with advanced cancer.
Advances in breast cancer treatment are improving outcomes for patients with the disease; however, treatments are increasing these patients' risk for cardiovascular diseases.
Study compared the effect of treatments on quality of life in treatment-naïve patients with HNC vs those who underwent radiotherapy and/or chemotherapy, and compared with cancer-free patients.
A randomized prospective study determined the effectiveness of the Restoring Body Image after Cancer (ReBIC) intervention in women breast cancer survivors who reported struggling with body image issues and sexual functioning.
In this study, researchers sought to determine the effect depressive symptoms during treatment planning had on immediate and long-term outcomes for patients with head and neck cancer.
In a phase 3 study presented at the 2018 Gastrointestinal Cancers Symposium, researchers reported on OS outcomes with gemcitabine plus S-1 vs gemcitabine plus cisplatin in patients with advanced biliary tract cancer.
Improved therapies and better screening has led to a plunge in breast cancer deaths over the last two decades.
Comparison of Survival Outcomes Between Radical Hysterectomy and Definitive Radiochemotherapy in Stage IB1 and IIA1 Cervical Cancer
[Cancer Management and Research] A comparison study evaluated whether radical hysterectomy or radiochemotherapy provides superior survival outcomes for patients with stage IB1 or IIA1 cervical cancer.
Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.
Using data from the TUS-CPS, researchers sought to determine the effect of pharmaceutical smoking cessation aids on long-term quit rates among patients who smoke tobacco.
Although dynapenia and weak HGS is associated with poor outcomes in patients with cancer, it is not routinely assessed in this population.
Researchers examined the impact of BEAT Cancer intervention on sleep for breast cancer survivors.
Adverse event rates were similar in both trial groups, though patients treated with TTFields were much more likely to have mild to moderate skin toxicity.
Capecitabine and Oxaliplatin as First and Second Line Treatment for Locally Advanced and Metastatic Pancreatic Ductal Adenocarcinoma
[Journal of Gastrointestinal Oncology] This research evaluates the use of capecitabine and oxaliplatin (CAPOX) for first or second-line treatment of locally advanced or metastatic PDAC.
In a retrospective study of SEER-Medicare data, researchers determined the survival outcomes of women with breast cancer and comorbid mental illness vs those without mental illness.
A survey of 754 cancer survivors sought to determine the association between number of neurotoxicities such as CIN, hearing loss, and tinnitus and outcomes for these patients.
Clinical Aspects of Foot Health and Their Influence on Quality of Life Among Breast Cancer Survivors: A Case-control Study
[Cancer Management and Research] Researchers determined the effect of breast cancer and its treatment on quality of life relative to foot health issues.
Fifty-five percent of patients treated with pembrolizumab survived through 24-months compared with 43% of patients treated with ipilimumab.
Trial investigates which of 3 maintenance regimens of nab-paclitaxel has the most ideal impact on quality of life in patients with metastatic breast cancer. Results were presented at SABCS 2017.
Novel weight reduction plan helps breast cancer survivors achieve and maintain a healthy weight and glucose level, according to a presentation at SABCS 2017.
Choosing the optimal adjuvant therapy option for a patient with early-stage HR-positive breast cancer should be a continuous discussion with the patient, according to a presentation at SABCS 2017.
A comparison of adjuvant endocrine therapies showed one option provided greater reduction in disease recurrence among premenopausal women with ER+ breast cancer.
A head-to-head comparison investigated whether patients with multiple myeloma achieved greater prolongation in overall survival with daratumumab monotherapy or pomalidomide plus low-dose dexamethasone.
New research on the benefits of high-fiber diets for CRC survivors took its findings one step further and identified the type of fiber consumed and which provided better benefits.
Improved survival in pediatric patients with standard-risk ALL has shifted the focus toward reducing treatment burden and toxicity; therefore, researchers sought to determine the effects of reduced DI chemotherapy on relapse and survival.
Researchers evaluated the effectiveness of online learning modules on physical activity counseling for oncology nurses. Although the modules improved nurses' counseling practices, they did not resolve the issue of physical activity in survivors.
Lomustine plus bevacizumab may increase progression-free, but not overall, survival versus lomustine alone in progressive glioblastoma.
Data on psychosocial and psychiatric variables of patients with HNC prior to treatment was analyzed to determine the extent of cognitive impairment and quality of life for patients with head and neck cancer, and its impact on patient outcomes.
Women with ER-positive BC who stop therapy after 5 years have steady recurrence rate up to 20 years afterward.
[Cancer Management and Research] This study examines the advances that pembrolizumab has made in melanoma and upcoming research that may further improve melanoma treatment.
Using a data sample from the CDC National Program for Cancer Registries, investigators determined how demographic factors — age, race, and sex — impact 5-year survival rates for HPV-associated cancers from initial diagnosis until death.
A randomized study assessed the impact of ConquerFear, a novel intervention developed from various models of cognitive therapy, and Taking-it-Easy, an intervention based on models that promote relaxation, on cancer survivors' ability to manage their fear of cancer recurrence.
In a prospective study, researchers assessed survival and quality of life measures for patients with advanced cancer in relation to where they are discharged from hospital: postacute care (PAC), hospice, or home without hospice.
A comparative case study of 12 advanced primary care practices identified the 3 factors that are barriers to integrating comprehensive cancer survivorship services into primary care practices.
This study evaluated the feasibility and potential efficacy of a yoga intervention for patients with NSCLC and their caregivers.
Comparison study via questionnaires assessed patients' and oncologists' views on likelihood of dying as a result of treatment shortly after beginning intensive or nonintensive chemotherapy for AML, and their views on prognosis 1 month later.
Researchers randomly assigned 478 patients with R/R MM to receive carfilzomib 70 mg/m2 once weekly plus dexamethasone or carfilzomib 27 mg/m2 twice weekly plus dexamethasone.
When her search for a realistic nipple to complete her breast reconstruction alluded Michelle Kolath-Arbel, a breast cancer survivor, she decided to make one herself.
The transition from active treatment to survivorship for patients with breast cancer can be as complex as the disease. An oncology social worker discusses the challenges of this "new unknown" in the continuum of care.
Investigators assessed the impact of advances over time in the treatment of Hodgkin lymphoma on all-cause mortality in patients with Hodgkin lymphoma who received radiotherapy alone or with chemotherapy.
Patients with head and neck cancer treated at hospitals attaining the combined metric of a 90 percent or higher negative margin rate and 80% percent of cases achieving a LNY of 18 or more experienced a significant reduction in mortality.
A cross-sectional survey revealed the impact of symptoms and economic burden on quality of life for survivors of gastrointestinal cancer.
This study explored the potential for pregnancy and breastfeeding among women who survived breast cancer, particularly those with ER-positive disease, and the impact of pregnancy on disease recurrence.
Aggressive de-escalation of chemoradiation after surgery in patients with HPV-associated OPSCC led to similar disease control and improved quality of life and safety profile compared with historical controls, according to data presented at the ASTRO 59th Annual Meeting.
A retrospective analysis of 28 studies determined that overall response rates for patients with ITP were similar treated with hydroxychloroquine, danazol, or dapsone in the second-line setting were similar.
Researchers present findings of a phase 2 study that compared PFS when SBRT is administered prior to maintenance chemotherapy in patients with limited metastatic NSCLC vs chemotherapy alone. Data was presented at ASTRO 59th Annual Meeting.
Retrospective analysis of data from more than 19,000 women revealed that all-cause mortality rates are higher in women with breast cancer who have a prior diagnosis of a mental illness.
Overall survival was significantly prolonged in patients with advanced melanoma who were treated with nivolumab plus ipilimumab compared with either drug alone, according to results from the Checkmate 067 study.
Gemtuzumab ozogamicin (Mylotarg) was granted US FDA approval for the treatment of relapsed or refractory CD-33 positive AML in patients ages 2 years and older and newly diagnosed CD-33 positive AML in adult patients.
Lenalidomide reduced the relative risk of disease progression in a clinical trial of patients with chronic lymphocytic leukemia who did not achieve MRD negative disease state after first-line chemoimmunotherapy.
Comparison study shows significantly improved overall survival and progression-free survival in patients with advanced LPS treated with eribulin vs dacarbazine.
Oncological Safety and Cosmetic Outcomes in Oncoplastic Breast Conservation Surgery, a Review of the Best Level of Evidence Literature
[Breast Cancer: Targets and Therapy] This review examines oncological safety in oncoplastic breast conservation surgery, local recurrence and patient outcome, postoperative complications, and cosmetic outcomes.
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