Experts have identified three major sources of high cancer costs and argue that cancer doctors can likely reduce them without harm to patients. The cost-cutting proposals call for changes in routine clinical practice involved in end-of-life care, medical imaging, and drug pricing.
For women with breast cancer, incorporating yoga into radiotherapy is associated with a lasting improvement in quality of life.
A panel of 55 genes, almost all of which are impacted by the loss of a particular protein, appears to predict if breast cancer will become invasive, leading to poorer survival, according to new research.
Acceptable long-term safety, positive therapy responses persist after drug discontinuation
Severe skin reactions during radiation therapy could be prevented by applying a thin transparent silicone dressing to the skin from the first day of treatment, according to clinical research from New Zealand.
An increase in workload increases odds of death, whereas an increase in percentage of nurses with degrees cuts death rates, research found.
Recent articles discussed the need to develop both a learning IT system for cancer that enables real-time data analysis from cancer patients in a variety of care settings.
The American Cancer Society (ACS) has published its latest annual report on cancer incidence and mortality, and the news is good.
Among women with mutations in BRCA1 or BRCA2, oophorectomy reduces the risk of developing ovarian, fallopian tube, or peritoneal cancer by 80 percent.
Men with prostate cancer on active surveillance should be informed of the risk of complications linked to repeated biopsies.
A chemical signature has been found in blood-forming stem cells that predict if a patient with acute myeloid leukemia (AML) will respond to chemotherapy.
Half of African-American men and a third of African-American women will receive a diagnosis of cancer in their lifetimes. The causes of cancer health disparities are complex, stemming from such factors as genetic susceptibility and family history.
Tests that require patients to collect a single stool sample at home and then send it to a lab for analysis will detect about 79% of colorectal cancers. A review of 19 studies examining eight different FITs also finds that the tests will correctly identify about 94% of patients who do not have cancers of the rectum or colon.
Adjuvant bevacizumab increases overall survival in cervical cancer, and two studies show benefits of bevacizumab on PFS in newly diagnosed glioblastoma as well.
Improvements in fatigue, IL-6, TNF-a, and IL-1B seen in a clinical trial that measured the effects of yoga practice in women survivors of breast cancer.
Breast cancer was diagnosed at earlier stages in women age 40 to 49 years who underwent routine screening mammography, and their tumors were less likely to require chemotherapy.
Among patients with advanced melanoma, presence of higher levels of the protein VEGF in blood was associated with poor response to treatment with the immunotherapy ipilimumab.
Positive margins linked to two-fold increased risk of ipsilateral breast tumor recurrence, according to consensus guidelines.
A new type of magnetic resonance imaging (MRI) scan, known as diffusion-weighted MRI, could improve care for myeloma and reduce reliance on bone marrow biopsies.
Health-related quality of life assessment in randomized clinical trials in small cell lung cancer provides added information in studies where the treatment arms do not differ in terms of efficacy.
Long-term outcomes of breast cancer patients receiving adjuvant accelerated partial breast irradiation after breast-conserving surgery show excellent tumor control with minimal late toxicity.
A new report from the American Cancer Society outlines the progress made and challenges that remain in fighting childhood cancer.
When comparing treatments designed to enable long-term breast preservation for older women with invasive breast cancer, researchers found that those treated with brachytherapy were at higher risk for a later mastectomy.
Treating mesothelioma with radiation before surgery resulted in a 3-year survival rate that was more than double compared with that of treating with surgery first, according to new research.
Why do children with Down syndrome who are being treated for acute lymphocytic leukemia sometimes require oral leucovorin after intrathecal methotrexate administration?
Targeted treatments for acute promyelocytic leukemia cause a cascade of molecular events that lead to cellular senescence and recovery. This action model could be activated in other types of cancers.
Researchers found a significantly reduced mortality risk for breast cancer survivors who run.
Combining high-dose interleukin-2 and personalized vaccines to activate patients' immune systems improves survival of metastatic melanoma even more than IL-2 alone.
High pretreatment VEGF levels have been linked to lower survival after ipilimumab treatment.
A new study found that most women who undergo conservative surgery for vulvar cancer experience little to no long-term disruption to sexuality and body image.
Long-term results of an EORTC trial show that 5- fluorouracil (FU)-based adjuvant chemotherapy after preoperative chemoradiotherapy for patients with cT3-resectable T4 M0 rectal cancer does not improve survival or disease-free survival.
Girls treated for Hodgkin's lymphoma during adolescence acquire a considerable risk of developing breast cancer.
Men who walked at a fast pace prior to a prostate cancer diagnosis had more regularly shaped blood vessels in their prostate tumors compared with men who walked slowly, providing a potential explanation for why exercise is linked to improved outcomes.
Twelve-week intervention linked to improved fatigue, vitality, lower levels of proinflammatory cytokines in participants.
Minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer at diagnosis than white patients and those in higher economic brackets.
Many women who are survivors of childhood cancer can become pregnant. This good news comes from the Childhood Cancer Survivor Study, in which nearly two-thirds of the women in the survivor group, initially unsuccessful at becoming pregnant, eventually conceived.
Although challenged, youth with cancer do not have higher rates of posttraumatic stress disorder.
Although complications from surgical care for cancer patients may seem infrequent, the costs associated with such outcomes are extremely high, according to researchers.
Little to no long-term disruption to sexuality or body image for women undergoing treatment for vulvar cancer found, according to a study published online.
Patients with head and neck cancer who are treated with an advanced form of radiation therapy may experience fewer side effects and be less likely to die from their disease than patients who receive standard radiation therapy.
Preventive surgery improves survival for women who are at greater risk of developing ovarian cancer, and it may be helpful for women at risk of developing breast cancer due to genetics.
A protein has been identified that may be a key culprit when breast cancer metastasizes to the brain.
Brisk walking before prostate cancer diagnosis has been associated with more regularly-shaped blood vessels.
A biomarker, adenosine deaminase acting on RNA-1 (ADAR1), has been discovered, and it has the potential to improve the diagnosis, prognosis, and treatment of esophageal squamous cell carcinoma.
Measuring the amount of certain protein fragments and microRNAs in a woman's blood and breast tissue might enable the early diagnosis of breast cancer or prediction of its metastasis.
A higher 90-day mortality was seen after avoidable versus non-avoidable hospitalizations.
A new program designed to increase the overall satisfaction of patients undergoing esophageal surgery has resulted in lower patient costs and reduced times on both the operating table and in the hospital.
A new study demonstrates that nonpharmaceutical techniques can resolve sleep disturbance and insomnia in patients with cancer.
High-dose cytarabine in induction treatment improves the outcomes of adult patients with acute myeloid leukemia (AML).
The methods used to anesthetize patients with prostate cancer and control pain due to surgical resection of the prostate glands for adenocarcinoma may affect patients' long-term cancer outcomes, a study has found.
The leading National Cancer Institute-designated comprehensive cancer centers may not adequately help patients protect their fertility.
Findings among head and neck cancer patients treated with IMRT versus other types of radiation show significant improvements in cause-specific survival.
Cognitive behavioral therapy for insomnia (CBT-I) is the preferred choice over mindfulness-based stress reduction (MBSR) for nonpharmacologic management of insomnia in patients with cancer.
In a study that included more than 800 women who had undergone surgery for breast cancer, the majority reported some level of pain 12 months after surgery.
Women with HER2-positive breast cancer who had the highest levels of immune cells in their tumors gained the most benefit from presurgery treatment with chemotherapy and trastuzumab. These results were presented at the 2013 San Antonio Breast Cancer Symposium.
Combining the chemotherapy drugs docetaxel and carboplatin with the HER2-targeted therapy trastuzumab was identified to be an ideal postsurgery treatment option for patients with HER2-positive breast cancer.
Re-examination of data from four large studies of the benefits and harms of mammography screening shows that the benefits are more consistent across these studies than previously understood.
A definitive trial has indicated that low-level laser therapy (LLLT) reduces the occurrence of canker sores and improves quality of life in patients with head and neck squamous cell carcinoma.
Changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients, according to new research.
Omission of radiotherapy is a reasonable option for women 65 years or older who receive hormone therapy after breast-conserving surgery for hormone receptor-positive, axillary node-negative breast cancer.
Compared with their counterparts in cities, cancer patients living in rural areas tend to retire early after a cancer diagnosis, and are less likely to go on paid disability leave while undergoing treatment. These are some of the insights drawn from research that sought to determine the impact of a cancer diagnosis on life choices.
Improved treatments and technologies are leading to more children than ever who survive cancer. Unfortunately, about 70% of these children experience late effects from their disease.
Among 1,000 U.S. women screened annually for 10 years, 0.3 to 3.2 will avoid breast cancer death due to mammography.
Breast cancer survivors taking AIs, such as anastrozole, letrozole, and exemestane, experienced a reduction in joint pain if they exercised while on treatment. These results were presented at the 2013 San Antonio Breast Cancer Symposium.
In a study of women with triple-negative breast cancer, adding carboplatin or Avastin to standard chemotherapy drugs brought a sharp increase in the number of patients whose tumors shrank away completely. This was reported at the 2013 San Antonio Breast Cancer Symposium.
Death rates for lung cancer dropped at a faster pace than in previous years, according to this year's "Annual Report to the Nation on the Status of Cancer." The Report also noted declines in the death rates in colorectal, breast, and prostate cancers; however, mortality rates in some cancers have increased.
Treatment with zoledronate, a bisphosphonate, did not improve outcomes for women with chemoresistant breast cancer, according to initial results of a phase 3 clinical trial presented at the 2013 San Antonio Breast Cancer Symposium.
For women with metastatic breast cancer who had elevated amounts of CTCs in their blood after a first line of chemotherapy, switching immediately to a different chemotherapy did not improve overall survival or time to progression. These phase 3 clinical trial results were presented at the 2013 San Antonio Breast Cancer Symposium.
Genetically engineered cell therapies may bring hope to patients for whom standard treatments have been unsuccessful, according to two separate studies presented at the 2013 ASH Annual Meeting, in New Orleans, Louisiana.
A cell-surface protein called CD151 may serve as a biomarker that accurately predicts which patients with prostate cancer are likely to experience metastasis or recurrence.
The metabolic profile of cancer cells can be used to develop therapies and identify biomarkers associated with cancer outcome. New research has discovered an association between the oncometabolite 2-HG levels, DNA methylation patterns, and breast cancer prognosis.
With a deluge of promising new treatments for advanced prostate cancer, a new model of care is needed that emphasizes collaboration between urology and medical oncology clinicians.
Increased levels of the protein HSET in African American women with breast cancer were associated with worse outcomes, according to results presented at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, in Atlanta.
Older breast cancer survivors should follow an ongoing exercise program of resistance and impact training. Newly published research found that the bone benefit from 1 year of such training could be maintained, even with less exercise, up to a year later, which could help prevent bone fractures in the long run.
A series of 10 genes have been identified that may signify a trifecta of benefits for women with ovarian cancer. This 10-gene biomarker panel may identify the aggressiveness of a patient's disease, help predict survival outcomes, and result in novel therapeutic strategies tailored to patients with the most adverse survival outcomes.
Children with acute lymphoblastic leukemia (ALL), the most common form of pediatric cancer, can safely receive intravenous infusions of a reformulated mainstay of chemotherapy that has been delivered via painful IM injection for more than 40 years, research suggests.
Factors such as smoking and obesity increase the odds of early implant loss in women who undergo mastectomy and immediate breast reconstruction with implants.
Supplementing general anesthesia (GA) with neuraxial anesthesia during prostate cancer surgery is associated with improved oncological outcomes compared with GA alone.
A toxin linked to a targeted monoclonal antibody has shown compelling antitumor activity in patients with non-Hodgkin lymphomas (NHLs) who were no longer responding to treatment, according to a new report.
The ANA convened a panel to investigate the impact of fatigue on nurses and nursing. In this first article, the objectives of the NFPIP panel are explained.
Drastic reimbursement cuts for image-guided breast biopsies, and other medical imaging techniques in the 2014 Medicare Fee Schedule Final Rule, may further reduce women's access to mammography and other breast cancer services.
Framework for optimizing CRPC treatment should involve joint management by both a urologist and a medical oncologist.
A new study finds that survivors of hematopoietic stem cell transplant, an aggressive treatment for blood cancers, benefited from a two-part peer support process. The authors called this peer support process "expressive helping."
A groundbreaking international collaborative survey found that more than half of the world's population lives in countries where regulations that aim to stem drug misuse leave cancer patients without access to opioid medicines for managing cancer pain.
Serum levels of the interleukin-6 family cytokine leukemia inhibitory factor (LIF) are higher in patients who did not respond to radiation therapy, according to new research.
Radiotherapy has no benefit for some older women after surgery, and hormone treatment after surgery may provide a radiation alternative.
The minimally invasive procedure provides effective, immediate relief from the pain of vertebral compression fractures due to multiple myeloma.
Patients with stage III or IV melanoma who have not received treatment with BRAF inhibitors remain at risk for developing new primary melanomas (NPMs).
Lymphedema can be accurately assessed through the use of Bioelectrical Impedance Analysis (BIA) ratios, according to a new study.
Both patients and clinicians often confuse palliative care and hospice care. Palliative care clinicians offer 10 points to help explain the purpose of the former.
The physiological reserves of elderly patients with cancer were evaluated and the most relevant biomarkers indicating their functional biological age were described in a recent publication by the Elderly Task Force of the European Organization for Research and Treatment of Cancer.
Genomic and epigenomic alterations in the PAX gene family are associated with racial disparity in head and neck squamous cell carcinoma (HNSCC) survival, according to a study.
Men with prostate cancer who take the cholesterol-lowering drugs known as statins are significantly less likely to die from their cancer than men who do not take such medication, according to a new study.
For patients with early cancer, a nurse navigator intervention can improve patient experience and reduce problems with care, according to a study published online Nov. 25 in the Journal of Clinical Oncology.
Use of a minimally invasive endoscopic procedure to remove superficial, early-stage esophageal cancer is as effective as surgery that removes and rebuilds the esophagus, according to a new study.
Breast cancer is treated differently in men than in women, with regard to frequency of both mastectomy and radiation treatment.
Performing early stem cell transplants in patients with aggressive non-Hodgkin lymphoma does not improve overall survival in high-risk patients, according to a new study. However, early transplantation appears to be beneficial among the small group of patients who are at the very highest risk.
Black patients with metastatic colorectal cancer are less likely to be seen by cancer specialists or receive cancer treatments. The study did not ascribe a specific cause for the racial disparities but offered six possible explanations.
The best outcome for wait times falls between 2.1 and 12.0 weeks time.
More than 500,000 women in the United States have a breast biopsy each year. Percutaneous biopsies are associated with fewer complications than the surgical approach, but short-term side effects such as pain and emotional distress are still significant.
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