In elderly patients with moderate- to high-risk early stage breast cancer for whom standard chemotherapy is too toxic, capecitabine did not improve outcomes when tested as monotherapy, according to recent data.
A key discovery has advanced the understanding of why some patients respond to ipilimumab, an immunotherapy drug, whereas others show less response.
The anticancer drug galeterone has proved successful in lowering prostate-specific antigen levels in men with castration-resistant prostate cancer (CRPC).
A method to determine which patients with ovarian cancer are more likely to respond well to the new anticancer drug rucaparib has been discovered.
Employing financial incentives to encourage smokers to reduce cigarette use can be a successful ploy.
Women with symptoms of serious mental illness are significantly less likely to receive the three routine cancer screenings of Pap tests, mammography, and clinical breast examinations than women in the general population.
Adult survivors of retinoblastoma, a type of eye cancer that usually develops in early childhood, are typically free from long-lasting effects, a new study shows.
Ovarian clear cell adenocarcinoma (CCA), a rare and aggressive form of ovarian cancer, may be treated by employing pelvic radiotherapy (RT).
The surveillance and follow-up of breast cancer survivors has the potential to improve, from the perspective of both patients and the health system.
Significant and durable improvements in insomnia and sleep quality, with and without armodafinil
A genetic test has been developed to identify which men are at higher risk for prostate cancer recurrence after localized treatment with surgery or radiotherapy.
A novel medical-imaging technology, TexRAD, which analyzes the texture of tumors, has been shown in trials to enable early diagnosis of colorectal cancer in patients not responding to the standard cancer therapy better than other available tumor markers.
Prostate cancer patients with hereditary mutations in the BRCA genes do not respond as well to conventional treatment such as surgery and radiotherapy, and they have a lower survival rate than patients who do not have these genetic mutations.
A chemotherapy regimen of procarbazine, lomustine (CCNU), and vincristine (PCV) administered after radiation therapy improved both progression-free survival and overall survival in adults with low-grade gliomas.
A new approach to treatment using a cancer-killing virus combined with a chemotherapy drug may offer hope to those with advanced and recurrent forms of metastatic ovarian cancer.
Nearly one quarter of all women who underwent initial breast conservation surgery (BCS) for breast cancer had a subsequent surgical intervention.
The current classification system for colorectal cancer, based on genetic profiles, cannot be used to predict drug responses to FOLFIRI.
Patients with a specific type of esophageal cancer survived longer when they were given the latest lung cancer drug, according to trial results.
Exercise offers several benefits for breast cancer survivors, including reduced symptoms of lymphedema, according to a new study.
The cost of nonbillable nursing hours needed for these programs may hinder compliance. The right technology can link treatment silos and lower this cost.
A new standard of care for children facing acute myeloid leukemia (AML) may be clear, following a multiyear study.
For the first time, researchers have found that exposure to radioactive iodine is associated with more aggressive forms of thyroid cancer, according to a careful study of over a thousand individuals.
Psychosocial decline occurs in an estimated one-third of patients undergoing radiotherapy for cancer. These declines may sometimes be ameliorated by vigilant recognition of the need to refer patients for psychosocial support interventions.
Proportion undergoing testing varies by demographic and health-related factors, and by state, a study found.
Patients with non-small lung cancer (NSCLC) that received postoperative radiation therapy (PORT) lived an average of 4 months longer, when compared with patients who had the same disease progression and treatment criteria.
Excellent long-term, local control for medically inoperable, early stage lung cancer patients is possible, according to a review of data from an institutional patient registry on stereotactic body radiotherapy (SBRT).
Research indicates smoking cessation boosts survival, even if there has been a weight gain.
Treatment with a combination of the drugs sargramostim plus ipilimumab, rather than ipilimumab alone, yielded longer overall survival and lower toxicity for patients with metastatic melanoma.
Researchers have demonstrated that employing mindfulness meditation or being a member of a support group has a positive physical impact at the cellular level in breast cancer survivors.
A new correlation discovered between specific molecular disease features and subgroups of patients with different prognoses could make identification of chronic lymphocytic leukemia (CLL) prognosis at the time of diagnosis possible.
Researchers have demonstrated for the first time that the quality level of diagnostic staging using biopsy in patients with bladder cancer is directly linked with their survival.
Significant advances have been made in screening for lung cancer and in targeting those patients who will benefit most from it. This study examines the impact of screening and treatment modalities on elderly patients.
Hospital readmission rates after colorectal cancer surgery showed little variation when the data was adjusted to account for patient characteristics, coexisting illnesses, and operation types.
Oncology Nurse Advisor talked with Diane Meier, MD, about the components of quality palliative care. Dr. Meier is director of the Center to Advance Palliative Care and vice-chair for Public Policy and a professor at Icahn School of Medicine at Mount Sinai in New York City; she is also the co-author of a new book on palliative care.
Diffuse optical spectroscopic tomographic imaging (DOST) may be useful in predicting which patients will best respond to chemotherapy used to reduce breast cancer tumors before surgery, according to a new study.
A new, collaborative model in cancer care aims to reduce the rates at which patients go to intensive care or are readmitted to the hospital after discharge.
A new study has found that patients who received chest radiation for Wilms tumor may be more susceptible to breast cancer later in life, due to their radiation exposure.
The addition of trastuzumab to chemotherapy significantly improved the overall and disease-free survival of women with early stage HER2-positive breast cancer.
Oncology nurses at a New York cancer center successfully reduced the rate of CAUTIs at their facility to zero with a novel program that gives nurses autonomy in making care decisions for patients with urinary catheters.
Location of a breast cancer tumor, on the left or right side, does not impact overall survival in patients treated with breast-conserving surgery and adjuvant external beam radiation therapy.
By utilizing both facial scanning software and 3-D printing, researchers have developed an inexpensive way to make facial prostheses for patients with eye cancer.
Telephone counseling sessions increase likelihood that childhood cancer survivors receive cardiac screening
Written heart screening guidelines plus telephone counseling doubled the probability of childhood cancer patients receiving cardiac monitoring.
Removal of an entire lung lobe may offer patients with early stage lung cancer better overall survival compared with a partial resection.
As cancer care evolves toward anticipatory rather than reactionary care, oncology nurses should consider developing important new skills.
A new drug in development may offer analternative to standard chemotherapy for patient with T-cell acute lymphoblastic leukemia, according to new research.
A federal prescription-subsidy program for low-income Medicare recipients has increased adherence to hormone therapy to prevent breast cancer recurrence after surgery, according to recent data.
Young men who have a high risk of becoming sterile the option to bank a small piece of testicular tissue prior to cancer treatment.
In cases of bladder cancer, omission of muscle in specimen or its mention in pathology report is linked to increased mortality.
Examination of the DNA of a thyroid cancer survivor has revealed details about resistance to the drug everolimus, according to researchers.
A new technique to treat retinoblastoma may help prevent eye loss, blindness, or death in children with advanced forms of the disease.
Clinical trials could benefit from a greater number of participants with a dedicated cooperative network to support rural community cancer centers.
Lung cancer can remain dormant in the body for many years before emerging in an aggressive form, according to new research.
Improved tyrosine kinase inhibitor (TKI) selectively activates in tumor tissue, minimizing side effects in patients
A new strategy developed by an interdisciplinary team of researchers aims to reduce the side effects connected to use of tyrosine kinase inhibitors (TKIs).
Coupling immunotherapy to radiotherapy treatment could help prevent cancers from becoming resistant to treatment, according to a new study.
A recent review has found insufficient consistent data exist to recommend a change in use of levothyroxine as the only drug needed to treat hypothyroidism.
Is sequencing important when administering chemotherapy on the same day?
In a study of more than 1.1 million cancer patients who had surgery, almost 5 percent died within one month of their operation. Lack of access to quality care a major factor in these deaths, researchers say.
Treatnent with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to phase II trial data.
Addition of the experimental drug cediranib to standard chemotherapy improves tumor shrinkage and adds a modest improvement in progression-free survival for patients with cervical cancer that has recurred after treatment.
After failure of platinum-based chemotherapy, the tyrosine kinase inhibitor (TKI) afatinib significantly improved progression-free survival in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.
Guidelines for managing chemotherapy-induced nausea and vomiting direct management toward risk assessment and prophylactic antiemetics.
Findings suggest that elevated levels of cholesterol and triglycerides may be linked with greater risk of the prostate cancer recurrence, but normalization of blood fats may reduce risk.
Human epidermal growth factor receptor 2 (HER2) mutations may offer an important treatment target in a subset of patients with non-small cell lung cancer.
For younger patients with an acute lymphoblastic leukemia (ALL) subtype, modifying treatment based on chemotherapy response can make a vital difference.
Successful colonoscopy is closely dependent on good bowel preparation, and poor bowel prep often leads to missed precancerous lesions.
After surviving pancreatic cancer, a patient learns the disease metastasized to his liver. But this patient was not ready to give up. With the support of a liver surgeon, he underwent surgery and beat his disease.
Smokers with cancer using e-cigarettes (in addition to traditional cigarettes) were found to be more nicotine dependent and equally or less likely to have quit smoking traditional cigarettes than nonusers.
Combination treatment for melanoma achieves significant progression-free survival and response rates
Combination therapy with both BRAF inhibitor vemurafenib and MEK inhibitor cobimetinib achieved superior results over vemurafenib plus placebo for BRAF-mutation positive melanoma.
Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study confirms use of trastuzumab for HER2-positive breast cancer
The use of trastuzumab (Herceptin) as the standard-of-care treatment for HER2-positive breast cancer has been supported by the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study.
Researchers have successfully tested a new tool that will help surgeons better distinguish cancerous breast tissue from normal tissue, which should lower the mount of repeat procedures needed.
A targeted combination drug therapy has shown efficacy for metastatic melanoma, showing reduction in both mortality and disease progression.
A newly developed antifungal has proved as effective against invasive mold disease in cancer patients as the standardly used drug, voriconazole, with fewer side effects.
A shoulder surgical aid, known as the Spider Limb Positioner, was adapted successfully to conduct a left hip disarticulation on a patient with melanoma.
Patients that have inoperable advanced hepatocellular carcinoma (HCC) may live significantly longer by receiving a combined therapy, according to recent trial results.
An experimental regimen of once-weekly breast irradiation after lumpectomy provides more convenience to patients at less expense, and results in better completion rates of prescribed radiation treatment.
Studies show improved progression-free melanoma survival for both cobimetinib combined with vemurafenib, and dabrafenib combined with trametinib.
Prostate cancer treatment controversy continues as study finds watchful waiting not enough for some men
An active controversy among oncologists concerns watchful waiting versus more active treatment for prostate cancer.
Radiation therapy with concurrent paclitaxel chemotherapy after surgery can be effective to treat patients with high-risk endometrial cancer, according to new research.
A medical center in New Jersey makes the most of a rare opportunity to rebuild from the ground up. Its innovative patient rooms follow evidence-based design, a new concept in health care architecture.
A PARP inhibitor in oral tablet form, given in combination with chemotherapy, was deemed safe for heavily pretreated patients with ovarian cancer.
Smokers with cancer who used e-cigarettes along with traditional cigarettes were more dependent on nicotine, and the long-term safety of the devices still unclear, researchers caution.
Malignant melanoma was differentiated from benign skin lesions with high accuracy in a pivotal clinical utility study of the Myriad myPath Melanoma test.
Patients with cancer who use e-cigarettes as a form of smoking cessation are equally or less likely to quit smoking.
About 14.5 million U.S. cancer survivors are alive today, but aging population and increasing obesity threaten progress.
Scientists have developed a tool to distinguish each breast cancer subtype, research that could improve treatments and targeting of treatments for the disease.
Shorter time to testosterone recovery with 18 versus 36 months androgen deprivation therapy.
Breast cancer cells can lay the groundwork for their own metastasis throughout the body by coaxing cells within lymphatic vessels to send out tumor-welcoming signals.
Protein deletion predicts length of progression free survival (PFS) in patients with non-small cell lung cancer (NSCLC)
Deletion of the Bcl-2-like protein 11 (BIM) in advanced non-small cell lung cancer has been associated with shorter progression free survival (PFS).
Women treated for Hodgkin lymphoma will be able to better understand their risks of future infertility after researchers estimated their risk of premature menopause with different treatments.
Researchers in Australia examined patient and tumor characteristics of melanomas for higher mitotic rates (a marker of tumor cell growth) in an effort to increase early detection.
For men with early-stage prostate cancer, watching waiting is not always the best course of action, especially for black patients.
A subset of patients with stage III colon cancer had improved survival rates when treated with irinotecan-based therapy, according to recent research.
Weekend hospital admission for pediatric patients with newly diagnosed leukemia is associated with a longer length of stay, slightly longer wait to start chemotherapy, and higher risk for respiratory failure.
Study raises questions about the effect of soy's estrogen-like properties.
A protein named p66ShcA shows promise as a biomarker to identify breast cancers with poor prognoses, according to new research.
Rates of death resulting from opioid analgesic overdoses are lower in states that allow medical use of marijuana compared with states without such laws.
Patients with advanced laryngeal cancer appear to have better survival if they are treated with surgery than with nonsurgical chemoradiation.
A select team of immune-system cells from patients with leukemia can be multiplied in the laboratory, creating a horde of natural killer cells that can be used to target and destroy the cancer cells.
For patients with cancer, late admission more likely for younger patients, married men, hematologic malignancies.
A drug originally used to treat ovarian cancer has shown promising results in patients with advanced peritoneal cancers during a phase I clinical trial.
- Key discovery in understanding successes and failures of immunotherapy
- Added sugars may increase blood pressure more than high salt consumption
- Researchers identify biological indicator of response to new ovarian cancer drug
- Managing obesity should be part of cancer care
- Galeterone active in one form of castration-resistant prostate cancer
- Importance of sequence in administering premeds with paclitaxel
- Tamoxifen found to lower breast cancer rates among high-risk women in trial
- SABCS: Male breast cancer prognosis falls behind that for women
- Pembrolizumab safe, and even effective in some patients, for triple-negative breast cancer
- Capecitabine does not improve survival in elderly patients with early stage breast cancer
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|