Overall Survival in Advanced Melanoma Improved With Nivolumab, Ipilimumab Combination

Overall Survival in Advanced Melanoma Improved With Nivolumab, Ipilimumab Combination

Overall survival was significantly prolonged in patients with advanced melanoma who were treated with nivolumab plus ipilimumab compared with either drug alone, according to results from the Checkmate 067 study.

FDA Approves Gemtuzumab Ozogamicin for CD-33 Positive Acute Myeloid Leukemia

FDA Approves Gemtuzumab Ozogamicin for CD-33 Positive Acute Myeloid Leukemia

Gemtuzumab ozogamicin (Mylotarg) was granted US FDA approval for the treatment of relapsed or refractory CD-33 positive AML in patients ages 2 years and older and newly diagnosed CD-33 positive AML in adult patients.

Progression-Free Survival in CLL Prolonged With Maintenance Lenalidomide

Progression-Free Survival in CLL Prolonged With Maintenance Lenalidomide

Lenalidomide reduced the relative risk of disease progression in a clinical trial of patients with chronic lymphocytic leukemia who did not achieve MRD negative disease state after first-line chemoimmunotherapy.

Progression-Free, Overall Survival in Liposarcoma Improved With Eribulin vs Dacarbazine

Progression-Free, Overall Survival in Liposarcoma Improved With Eribulin vs Dacarbazine

Comparison study shows significantly improved overall survival and progression-free survival in patients with advanced LPS treated with eribulin vs dacarbazine.

Oncological Safety and Cosmetic Outcomes in Oncoplastic Breast Conservation Surgery, a Review of the Best Level of Evidence Literature

Oncological Safety and Cosmetic Outcomes in Oncoplastic Breast Conservation Surgery, a Review of the Best Level of Evidence Literature

[Breast Cancer: Targets and Therapy] This review examines oncological safety in oncoplastic breast conservation surgery, local recurrence and patient outcome, postoperative complications, and cosmetic outcomes.

Niraparib Maintains Quality of Life in Recurrent Ovarian Cancer

Niraparib Maintains Quality of Life in Recurrent Ovarian Cancer

Administering niraparib to patients with recurrent ovarian cancer after CR or PR to platinum-based chemotherapy may allow patients to continuously maintain QOL during treatment, reported researchers in presentation at ESMO 2017 Congress.

Reduced-Dose Sorafenib Effective and Economical in Hepatocellular Carcinoma

Reduced-Dose Sorafenib Effective and Economical in Hepatocellular Carcinoma

Reducing the initial dose of sorafenib was shown to have some benefits — such as reduced pill burden, lower costs, and decreased AE-related discontinuation rates — and OS was noninferior compared with the standard dose in patients with hepatocellular carcinoma.

Carfilzomib Improves Overall Survival in Relapsed/Refractory Multiple Myeloma

Carfilzomib Improves Overall Survival in Relapsed/Refractory Multiple Myeloma

The first interim analysis of the ENDEAVOR trial reported superiority of carfilzomib in some outcomes; however, data on overall survival were not available. This second interim analysis reports on overall survival with carfilzomib for patients with relapsed/refractory multiple myeloma.

Cancer Patient Caregivers Have Increased Burden With Assessment Dissonance

Cancer Patient Caregivers Have Increased Burden With Assessment Dissonance

There is an increased burden on caregivers to not only assist with IADLs but also to assess patient conditions and provide health care information.

Hospital Volume, Quality Impact Survival in Ovarian Cancer

Hospital Volume, Quality Impact Survival in Ovarian Cancer

Survival rate were worse for lower volume hospitals with higher quality scores, versus higher volume hospitals.

Pain Management, Cancer Care at End-of-Life Improved by Caregiver Education, Training Intervention

Pain Management, Cancer Care at End-of-Life Improved by Caregiver Education, Training Intervention

Novel intervention focuses on caregivers' beliefs, knowledge, and skills regarding home care for patients with cancer resulting in improved pain management and better overall care at the end of life.

Decitabine Improves Overall Survival, Overall Response Rate in Chronic Myelomonocytic Leukemia

Decitabine Improves Overall Survival, Overall Response Rate in Chronic Myelomonocytic Leukemia

Patients with high-risk chronic myelomonocytic leukemia (CMML), a MDS/myeloproliferative neoplasm, may experience prolonged overall survival and increased overall response rate from treatment with decitabine.

Resistance Training, Nutritional Interventions Prevent Muscle Loss During, After Radiotherapy for Head and Neck Cancer

Resistance Training, Nutritional Interventions Prevent Muscle Loss During, After Radiotherapy for Head and Neck Cancer

Intervention with resistance training and nutritional supplements during and after radiation therapy is not only feasible, but also shown to prevent loss of muscle mass and improve quality of life in patients with head and neck cancer (HNC).

Undergoing CT Lung Cancer Screening May Motivate Quit Attempts in Persons at High Risk

Undergoing CT Lung Cancer Screening May Motivate Quit Attempts in Persons at High Risk

Contrary to some concerns, persons at high risk for lung cancer who undergo CT lung scans are more likely to attempt smoking cessation regardless of their test results compared with unscreened persons.

Virtual Reality Offers New Experiences to Patients in Hospice

Virtual Reality Offers New Experiences to Patients in Hospice

A London hospice facility's experiment with virtual reality offers patients at the end of life the chance to explore the world beyond their bed.

Obesity in Adolescents Ups Colon and Rectal Cancer Risk in Adulthood

Obesity in Adolescents Ups Colon and Rectal Cancer Risk in Adulthood

Overweight teens in Israel had about a 53 percent higher risk for colon cancer as adults, researchers found.

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

Use of antiperspirant or deodorant does not adversely affect potential for dermal toxicity or surface concentrations of aluminum in the axilla in women undergoing radiation therapy for breast cancer.

Survival Predictions for NSCLC Accurate With the Lung Cancer Prognostic Index

Survival Predictions for NSCLC Accurate With the Lung Cancer Prognostic Index

The Lung Cancer Prognostic Index (LCPI) provides additional relevant prognostic data for patients with NSCL and may lead to better outcomes.

Rare Case of Langerhans Cell Histiocytosis With Prior ITP Highlights Diagnostic Challenge for Clinicians

Rare Case of Langerhans Cell Histiocytosis With Prior ITP Highlights Diagnostic Challenge for Clinicians

A rare case of Langerhans cell histiocytosis (LCH) in a patient with idiopathic thrombocytopenic purpura (ITP) highlights the difficulty in diagnosing LCH.

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

This research aims to assess the correlation between quality of life (QoL) and severity of dermatological toxicity in patients with metastatic colorectal cancer.

Neuropathic Cancer Pain Linked to Reduced Quality of Life

Neuropathic Cancer Pain Linked to Reduced Quality of Life

Results of a recent study showed that neuropathic cancer pain (NCP) in patients with cancer was not only associated with a worsened quality of life but is also not adequately managed.

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

Two recent studies examined the benefits of using a 3D bioabsorbable marker to indicate the tumor bed in women with breast cancer who underwent breast conserving surgery (BCS).

Rates at Some Milestones May Indicate Clinical Trial Results for Immunotherapeutics

Rates at Some Milestones May Indicate Clinical Trial Results for Immunotherapeutics

An analysis of rates at certain milestones in clinical trials of treatments for mNSCLC suggests these rates reflect end point results for immunotherapies vs targeted and conventional therapies.

Lenvatinib Improves OS, PFS in Radioiodine-Refractory Differentiated Thyroid Cancer in All Older Patients

Lenvatinib Improves OS, PFS in Radioiodine-Refractory Differentiated Thyroid Cancer in All Older Patients

Results from a sub-analysis of the impact of age on the safety and efficacy of lenvatinib in patients with RR-DTC in the SELECT trial showed that lenvatinib significantly increased PFS.

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

Regular use of NSAIDs after diagnosis of colorectal cancer correlated with improved survival in survivors with KRAS wild-type tumors.

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

Women with breast cancer who received capecitabine after adjuvant epirubicin had better quality of life (QOL) compared with those who received CMF after adjuvant therapy.

Clinical Trials May Benefit Oncology Patients

Clinical Trials May Benefit Oncology Patients

Research on the effects of research demonstrated that oncology-related clinical trials provide measurable benefits in terms

Survivorship Care Plans: Providing A Blueprint for Health Care After Cancer

Survivorship Care Plans: Providing A Blueprint for Health Care After Cancer

Survivorship care plans can ensure that cancer survivors know their cancer and treatment history, and are equipped to maintain proper follow-up care.

Eating and Exercising Towards Better Health in Cancer Survivors

Eating and Exercising Towards Better Health in Cancer Survivors

Lifestyle changes that promote proper weight management, increased exercise, and a healthy diet have the potential to improve survivors' health and well-being.

Lay Navigation Program Improves Health Care, Health System Use, Costs for Older Cancer Survivors

Lay Navigation Program Improves Health Care, Health System Use, Costs for Older Cancer Survivors

Survivorship care plan successfully improves the overall survivorship care of older cancer survivors using lay navigators.

Innovative Navigation Strategies: The Patient Care Connect Program

Innovative Navigation Strategies: The Patient Care Connect Program

Older cancer survivors typically have higher severity of disease and pre-existing conditions, which makes their cancer treatment additionally challenging. The Patient Care Connect Program was created to help address these issues.

Young Cancer Survivors More Often Have Cost-Related Nonadherence

Young Cancer Survivors More Often Have Cost-Related Nonadherence

Risk of nonadherence was lower for survivors reporting a usual source of care than those without

United States Leads in Income-Based Health Care Inequalities

United States Leads in Income-Based Health Care Inequalities

More public tolerance for health care inequalities has been observed in the United States than other countries.

Neurocognitive Function Impacts Health-Related QOL in Advanced Lung Cancer

Neurocognitive Function Impacts Health-Related QOL in Advanced Lung Cancer

Study finds a correlation between various measures of neurocognitive function and health utility scores.

Survival Increased With First-Line Abiraterone-ADT Combination for Hormone-Naïve Prostate Cancer

Survival Increased With First-Line Abiraterone-ADT Combination for Hormone-Naïve Prostate Cancer

Addition of abiraterone to androgen deprivation therapy for patients with hormone-naïve advanced prostate cancer may be a new standard of care.

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

Study compared FOLFOXIRI/bevacizumab and FOLFOX/bevacizumab in patients with metastatic colorectal cancer.

CVD Risk Factors Identified in Long-Term Survivors of Pediatric Cancer

CVD Risk Factors Identified in Long-Term Survivors of Pediatric Cancer

Study implicates higher doses of cardiac radiotherapy and exposure to high-dose anthracyclines.

Palliative Care Improves Coping in Patients With Incurable Cancers

Palliative Care Improves Coping in Patients With Incurable Cancers

Active coping is associated with a better quality of life and a decrease in depression symptoms, study finds.

Survivors of Pediatric Cancers Suffering Less From Chronic Diseases

Survivors of Pediatric Cancers Suffering Less From Chronic Diseases

A decline in the incidence of serious chronic diseases in survivors of childhood cancer may be linked to changes in treatment protocols.

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

'Conquer Fear' decreased fear among survivors of breast and colorectal cancer and melanoma compared with relaxation techniques.

Quality of Life in Ovarian Cancer Not Diminished by Olaparib

Quality of Life in Ovarian Cancer Not Diminished by Olaparib

Change in FACT-O TOI score from baseline to 12 months did not differ significantly between maintenance olaparib and placebo.

ACS Survivorship Guidelines for Healthy Behaviors Beneficial for Colon Cancer Survivors

ACS Survivorship Guidelines for Healthy Behaviors Beneficial for Colon Cancer Survivors

Patients with stage III colon cancer who follow the ACS guidelines for a healthy lifestyle after adjuvant chemotherapy had longer disease-free survival and overall survival.

Home-based Symptom Management With Caregiver Involvement Improves HRQOL in Advanced Breast Cancer

Home-based Symptom Management With Caregiver Involvement Improves HRQOL in Advanced Breast Cancer

Trends in caregiver involvement in home-based patient care are introducing new avenues for symptom management and improved health-related quality of life for patients undergoing chemotherapy for advanced breast cancer.

Vaccine for Cervical Cancer Could Extend Survival in Relapsed Disease

Vaccine for Cervical Cancer Could Extend Survival in Relapsed Disease

Axalimogene filolisbac, an intravenous vaccine currently in clinical trials, could prevent often-fatal cervical cancer relapse.

High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels

High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels

Negative emotions were shown to motivate breast cancer survivors to engage in moderate-to-vigorous exercise, and can increase their daytime levels of cortisol.

Complete vs Incomplete Metastasectony for mRCC: Improved Survival, Decreased All-Cause Mortality

Complete vs Incomplete Metastasectony for mRCC: Improved Survival, Decreased All-Cause Mortality

Complete surgical metastasectomy correlated with increased survival in patients with metastatic renal cell carcinoma (mRCC) compared with incomplete surgical metastasectomy.

Survivorship Care Plans Specific to Head and Neck Cancers Enable Transition to Posttreatment Care

Survivorship Care Plans Specific to Head and Neck Cancers Enable Transition to Posttreatment Care

Disease-specific survivorship care plans (SCPs) for head and neck cancer support a successful transition to a healthy lifestyle after curative intent therapy of larynx and oral cavity/pharynx cancer.

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

A literature review noted improvements in quality of life after patients were coached and educated following radiotherapy for HPV-associated oropharyngeal cancers.

Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors

Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors

Including beans and whole grains such as rice in the diet is associated with a reduced burden of CRC in survivors.

Combination Therapy Plus Stem-Cell Tx Ups PFS in Multiple Myeloma

Combination Therapy Plus Stem-Cell Tx Ups PFS in Multiple Myeloma

Patients with myeloma that underwent transplantation in addition to RVD had significantly longer median progression-free survival compared to the group that received RVD alone.

Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab

Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab

A significantly higher 5-year survival rate was seen in a small subset of patients with NSCLC treated with nivolumab.

Pre-Op Training Program Improves Patient Outcomes

Pre-Op Training Program Improves Patient Outcomes

Program provides physical, nutritional, and psychological guidance

Whole Genome Sequencing Reveals that 12% of Childhood Cancer Survivors Have Mutations in Genes that Increase Cancer Risk

Whole Genome Sequencing Reveals that 12% of Childhood Cancer Survivors Have Mutations in Genes that Increase Cancer Risk

Whole genome sequencing of more than 3000 survivors of childhood cancers demonstrates the value of genetic testing for potential second cancers in this population.

Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors

Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors

Physical activity is proven to improve both physical and mental effects of cancer diagnosis and treatment, even if the activity needs to be modified to fit the patient's current abilities.

Continuing Nivolumab After Progression of Head and Neck Cancer May Improve Survival

Continuing Nivolumab After Progression of Head and Neck Cancer May Improve Survival

Continuing immunotherapy after disease progression extends survival for some patients with head and neck cancer.

Annual Report Shows Decline in Cancer Death Rates, 1975-2014

Annual Report Shows Decline in Cancer Death Rates, 1975-2014

The joint report states that overall cancer rates have decreased for men, women, and children in all major race and ethnic groups. However, progress has been limited for some cancers.

Survival Better for Hispanics, Blacks With Colorectal Cancer but HR-QoL Is Better for Whites

Survival Better for Hispanics, Blacks With Colorectal Cancer but HR-QoL Is Better for Whites

Although median survival is longer for Hispanic and black patients compared with white patients, health-related QoL is poor for minority patients.

Concurrent, Maintenance Therapy With Cediranib Maintains QOL in Ovarian Cancer

Concurrent, Maintenance Therapy With Cediranib Maintains QOL in Ovarian Cancer

Quality of life was maintained in patients with ovarian cancer who received chemotherapy with concurrent cediranib then cediranib alone as maintenance therapy.

Arm Measurements a Better Assessment of Nutritional Status in Childhood Cancer Survivors

Arm Measurements a Better Assessment of Nutritional Status in Childhood Cancer Survivors

Arm anthropometry is a better tool for assessing nutritional status of survivors of childhood cancer.

Little Difference in QoL Between Various Treatments, Active Surveillance in Prostate Cancer

Little Difference in QoL Between Various Treatments, Active Surveillance in Prostate Cancer

QoL after radical prostatectomy, EBRT, or brachytherapy vs active surveillance for prostate cancer are similar.

Preterm Birth, Low Birth Weight Rates Higher in AYA Cancer Survivors

Preterm Birth, Low Birth Weight Rates Higher in AYA Cancer Survivors

Cancer treatment during childbearing years increased risk of preterm birth and delivering low birth weight babies.

Pembrolizumab May Help Combat Mesothelioma

Pembrolizumab May Help Combat Mesothelioma

Checkpoint inhibitor pembrolizumab appears well-tolerated with antitumor activity in patients with malignant pleural mesothelioma.

Social Functioning Scores for Young Cancer Survivors Remain Lower Than Their Peers

Social Functioning Scores for Young Cancer Survivors Remain Lower Than Their Peers

AYAs continue to report lower social functioning scores than their peers 2 years after diagnosis.

Mortality Rates Highest Among Youngest Oncology Patients, Particularly Minorities

Mortality Rates Highest Among Youngest Oncology Patients, Particularly Minorities

Cancer deaths within 1 month of diagnosis occur most often in patients younger than 1 years, especially among Blacks and Hispanics.

Greaster Risk of Adverse Birth Outcomes for Young Cancer Survivors

Greaster Risk of Adverse Birth Outcomes for Young Cancer Survivors

Increased risks among live births for adolescent and young adult cancer survivors

Improved Survival, Fewer Second Cancers With Less Radiation Therapy for Childhood Cancers

Improved Survival, Fewer Second Cancers With Less Radiation Therapy for Childhood Cancers

A significant reduction in use of radiation therapy to treat childhood cancers improved survival, reduced second cancers in survivors.

Lasting Outcomes for Imatinib in Chronic Myeloid Leukemia

Lasting Outcomes for Imatinib in Chronic Myeloid Leukemia

The efficacy of imatinib for CML treatment persisted over time and long-term administration was not associated with unacceptable cumulative effects.

No Intervention for Small Thyroid Cancers May Cause Anxiety

No Intervention for Small Thyroid Cancers May Cause Anxiety

Deciding not to intervene for small, incidentally identified thyroid cancer may cause patients to experience anxiety and feelings of isolation.

Endometrial Cancer Survivors in High-Poverty Areas Have Impaired Access to Self-Care Resources

Endometrial Cancer Survivors in High-Poverty Areas Have Impaired Access to Self-Care Resources

Living in a high-poverty region is associated with lower access to obesity-related self-care resources.

Nonadherence to Guidelines, Low-Volume Centers Linked to Lower Cervical Cancer Survival

Nonadherence to Guidelines, Low-Volume Centers Linked to Lower Cervical Cancer Survival

Nonadherence to NCCN guideline treatment recommendations was strongly associated with decreased survival from early-stage cervical cancer.

SWOG Study Shows Robust, Longer Survival With Imatinib Therapy for GIST

SWOG Study Shows Robust, Longer Survival With Imatinib Therapy for GIST

A phase 3 analysis of SWOG Intergroup Trial S0033 reveals that imatinib significantly extends survival in patients with GIST.

Many Breast Cancer Survivors Remain Inactive After Treatment

Many Breast Cancer Survivors Remain Inactive After Treatment

Despite the known benefits of physical activity for breast cancer survivors, a large proportion of this population continues to be physically inactive after treatment.

Walking Improves Quality of Life in Patients with Advanced Cancer

Walking Improves Quality of Life in Patients with Advanced Cancer

Simply walking for 30 minutes 3 times a week has significant impact on symptom severity and ability to cope, as well as quality of life, for patients with advanced cancer.

ASCO Endorses ACS Head and Neck Survivorship Care Guideline

ASCO Endorses ACS Head and Neck Survivorship Care Guideline

ASCO endorses ACS head and neck survivorship care guideline, which supports health promotion, especially regarding tobacco cessation and dental care.

HMT Improves PFS in Serous Carcinoma of the Ovary, Peritoneum

HMT Improves PFS in Serous Carcinoma of the Ovary, Peritoneum

Individuals with serious carcinoma of the ovary or peritoneum experienced improved progression-free survival after hormone maintenance therapy.

Women May Significantly Benefit from Entering OB/GYN Clinical Trials

Women May Significantly Benefit from Entering OB/GYN Clinical Trials

The researchers hope the results will lead to an increase in clinicians offering trials to their patients and an increase in women volunteering to participate in trials.

SCLC: No Benefit from Pravastatin When Added to First-line Chemo

SCLC: No Benefit from Pravastatin When Added to First-line Chemo

The addition of pravastatin to first-line chemotherapy did not improve overall survival or progression-free survival in patients with small-cell lung cancer.

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based cognitive behavioral therapy has positive effects on sexual functioning in breast cancer survivors experiencing sexual dysfunction.

Tattoo Transforms Mastectomy Scars Into Personal Art for Breast Cancer Survivors

Tattoo Transforms Mastectomy Scars Into Personal Art for Breast Cancer Survivors

Painter and tattoo artist David Allen has used his skills to transform breasts scarred by surgical reconstruction into works of art.

Specialized Cancer Centers May Improve Outcomes in Children with Leukemia

Specialized Cancer Centers May Improve Outcomes in Children with Leukemia

The site of cancer care may partially explain survival differences between children and AYAs with ALL.

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients with hormone receptor-positive, HER2-negative, axillary lymph node-negative breast cancer who have a recurrence score of 11 to 25 may not benefit from chemotherapy.

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

Outcomes improved with short-course radiation and delay to surgery of 4 to 8 weeks.

E-cigarettes and Replacement Nicotine Therapy Safer Than Tobacco Use

E-cigarettes and Replacement Nicotine Therapy Safer Than Tobacco Use

E-cigarettes and replacement nicotine therapy deposit fewer harmful chemicals in the body that smoking.

1 Year of Adjuvant Trastuzumab Improves Long-Term DFS in Early Breast Cancer

1 Year of Adjuvant Trastuzumab Improves Long-Term DFS in Early Breast Cancer

Adjuvant trastuzumab following chemotherapy significantly improves long-term disease-free survival in women with HER2-positive early breast cancer, according to study data.

Chemo + Radiotherapy Efficacious in Muscle-invasive Bladder Cancer

Chemo + Radiotherapy Efficacious in Muscle-invasive Bladder Cancer

Adding chemotherapy with fluorouracil and mitomycin to radiotherapy improves locoregional control.

Targeting AR Mutations Promising in Metastatic Prostate Cancer

Targeting AR Mutations Promising in Metastatic Prostate Cancer

A higher overall number of genetic alterations in cell-free circulating tumor DNA (ctDNA) were associated with worse treatment outcomes.

Pembrolizumab Active Against Rare Melanoma, Extends Survival in Bladder Cancer

Pembrolizumab Active Against Rare Melanoma, Extends Survival in Bladder Cancer

Clinical trials show pembrolizumab active against mucosal melanoma, extends survival in bladder cancer.

Metabolic Syndrome More Likely After Platinum-Based Chemotherapy for Testicular Cancer

Metabolic Syndrome More Likely After Platinum-Based Chemotherapy for Testicular Cancer

Survivors of testicular cancer are more likely to develop metabolic syndrome after platinum-based chemotherapy.

Trends in Behaviors, Medical Practice Indicate Mortality From Melanoma Will Decline

Trends in Behaviors, Medical Practice Indicate Mortality From Melanoma Will Decline

Using statistical models, predictions were made for death rates from melanoma in 3 three countries and based on availability of a treatment.

HNSCC Survival Worse for Patients in Lower Socioeconomic Population

HNSCC Survival Worse for Patients in Lower Socioeconomic Population

Investigators determined the impact of socioeconomic status on disease status at presentation and survival among patients with head and neck squamous cell carcinoma.

Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence

Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence

In this study, the impact of cholesterol-lowering medications on breast cancer recurrence in women receiving adjuvant endocrine therapy was investigated.

Oral SCC Diagnosis Has Greater Affect on Sexual Behavior Than HPV Status

Oral SCC Diagnosis Has Greater Affect on Sexual Behavior Than HPV Status

The impact of oral squamous cell carcinoma (OSCC) diagnosis and treatment on sexual behavior and relationship stress with respect to HPV status was evaluated in this study. Participants included patients with HPV-positive and HPV-negative disease, as well as partners.

Young Adult Survivors of Childhood Cancer May Face Psychosexual Challenges

Young Adult Survivors of Childhood Cancer May Face Psychosexual Challenges

Survivors of childhood cancer who received certain neurotoxic therapies are less likely to have had sexual intercourse or to be in an intimate relationship, researchers found.

Some Early Breast Cancer Patients Should Have Breast Conservation Instead of Mastectomy

Some Early Breast Cancer Patients Should Have Breast Conservation Instead of Mastectomy

Investigators from the Netherlands present their research findings on survival in women with early stage breast cancer who underwent breast-conserving therapy vs mastectomy at the 2017 European Cancer Congress.

Postoperative Gemcitabine Plus Capecitabine: A New Standard of Care for Pancreatic Cancer

Postoperative Gemcitabine Plus Capecitabine: A New Standard of Care for Pancreatic Cancer

Use of Adjuvant gemcitabine plus capecitabine for patients with pancreatic cancer who have undergone tumor resection resulted in a modest increase short-term survival.

Adding Bicalutamide to Salvage RT Improves OS in Recurrent Prostate Cancer

Adding Bicalutamide to Salvage RT Improves OS in Recurrent Prostate Cancer

Investigators studied the effects of adding antiandrogen therapy to radiotherapy on cancer control and overall survival in men with prostate cancer recurrence after radical prostatectomy.

Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs

Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs

Cancer survivors who reported chronic neuropathic pain 5 years after diagnosis were approximately 50% less likely to retain their jobs than those without chronic neuropathic pain.

Soy Consumption Influences Tamoxifen Efficacy Against Breast Tumor Recurrence

Soy Consumption Influences Tamoxifen Efficacy Against Breast Tumor Recurrence

Lifelong soy consumption improves tamoxifen response in women with breast cancer; however, adding soy to diet after initiating tamoxifen therapy may not provide the same benefits.

New Study Shows Standard of Care for NSCLC Patients Leads to Improved Overall Survival

New Study Shows Standard of Care for NSCLC Patients Leads to Improved Overall Survival

There are a growing number of NSCLC patients with advanced disease who are opting to forgo treatment despite the fact that receiving standard of care treatment leads to a higher OS.

Study Suggest New Treatment Approaches for High-Risk Pediatric Leukemia

Study Suggest New Treatment Approaches for High-Risk Pediatric Leukemia

Three specific genetic alterations may help identify pediatric patients with AMKL at high risk who may benefit from allogeneic stem cell transplants.

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