In this study, researchers evaluated whether ruxolitinib, a JAK2 inhibitor that reduces symptoms in patients with myelofibrosis, would improve disease-related symptoms in patients with CLL.
Findings at 6 and 12 months after treatment for advanced head and neck cancer indicate a higher risk of recurrences for those reporting cachexia after their treatment.
Patients on active surveillance with stable disease may be candidates for less intense surveillance
Women with a history of breast cancer face a wide variety of challenges as they transition from the role of "patient" to "survivor".
New evidence indicates that depression can impact cancer outcomes following chemotherapy.
The timing of surgery taking place following an endometrial cancer diagnosis may adversely impact survival.
Study results indicate that herpetic cytomegalovirus infection prior to birth subjects the child to increased odds of developing pediatric acute lymphoblastic leukemia.
Although many men obtain a second opinion regarding their prostate cancer care options, they seldom deviate from the original course of action.
Seluminitinib in combination with an AKT inhibitor did not improve survival compared with modified FOLFOX in previously treated metastatic pancreatic cancer.
Weak social ties are associated with poorer survival and a higher risk of breast cancer recurrence, researchers say.
A new meta-analysis examines the impact of palliative care services on patients' and caregivers' quality of life and outcomes.
Patients with metastatic breast cancer have significantly diminished quality of life (QoL) compared with those without metastatic disease and those without breast cancer, a study presented at the 2016 San Antonio Breast Cancer Symposium.
A study using focus groups identifies barriers that impact the quality of survivorship care for Latina women with breast cancer.
The effects of a 2-treatment course of acupuncture on pain, nausea, and anxiety and ability to cope among women undergoing mastectomy was compared with usual care.
Even patients that quit smoking in their 60s can add years to their lives, researchers find.
The LIVESTRONG at the YMCA exercise program significantly improved physical activity, fitness, and quality of life in survivors of cancer.
Using the Kessler nonspecific mental/psychological distress scale, investigators examined whether AYA cancer survivor experienced greater mental distress and assessed their access to mental health care.
Loss of bone density related to chemotherapy and adjuvant therapy for breast cancer can lead to debilitating hip and vertebral fractures. This discussion discusses the impact of resistance training for these patients.
Studies show better physical function and quality of life for cancer patients who do strength training or aerobic activity.
Large cohort study assesses the frequency of, and factors associated with, ototoxicity in childhood cancer survivors who received platinum agents without cranial irradiation.
Research shows only modest improvements in the physical or mental health of childhood cancer survivors in recent decades.
A new card game helps patients and caregivers broach the difficult subject of end-of-life wishes and prioritize what's most important in their planning.
Study evaluates whether a web-based rehabilitation program can effectively improve pain, fatigue, strength, and quality of life for breast cancer survivors.
A nurse develops a tablet app that helps intubated patients communicate with their nurses, caregivers, and families.
Nearly one in five cancer survivors are taking medication for depression or anxiety years later.
Researchers observed a significant disparity in colon cancer mortality related to origin location, independent of confounding variables.
In this study, researchers assessed data on women who underwent breast cancer treatment to identify the factors associated with posttreatment imaging use.
Epidemiologic study reveals the impact of cancer and its treatment on diet quality among adult survivors of childhood cancers.
Researchers examined the long-term effects of a short-term culturally based dietary intervention on increasing the consumption of fruits and vegetables, decreasing fat, and changing biomarkers associated with recurrence in Hispanic breast cancer survivors.
Cancers that cause more readily noticeable physical changes can produce self-image challenges for patients. This discussion reviews what interventions can help validate patients' self-image concerns.
CDK4/6 Inhibitor Plus Aromatase Inhibitor Improves Progression-Free Survival in Metastatic Breast Cancer
Adding ribociclib to letrozole significantly improves progression-free survival for postmenopausal women with metastatic hormone receptor (HR)-positive breast cancer, compared with hormone therapy alone.
Internalizing, Externalizing Behavioral Problems a Significant Postdiagnosis Concern in Children With Cancer
Children with cancer are at risk for developing behavioral problems after diagnosis.
The United States has remained near the bottom of the Bloomberg Health-Care Efficiency Index since its creation in 2012.
Adding daratumumab to lenalidomide and dexamethasone significantly prolonged progression-free survival compared with lenalidomide plus dexamethasone alone in patients with relapsed or refractory multiple myeloma.
Severe fatigue is associated with unemployment and financial problems in survivors of Hodgkin lymphoma, highlighting the need for clinicians to address fatigue in these patients.
Patients with oropharyngeal tumors that harbor HPV16 have higher 5-year survival and lower recurrence rates than patients with tumors that harbor other HPV strains or are HPV-negative.
Prostate cancer survivors who maintain or begin recreational physical activity following cancer diagnosis report substantially higher quality of life than those who never exercise or stopped exercising after diagnosis.
Treatment with pembrolizumab better maintained health-related quality of life compared with chemotherapy in patients with advanced melanoma refractory to ipilimumab.
Continued adoption of stereotactic body radiation therapy (SBRT) to treat early stage NSCLC improved OS and lung cancer-specific survival, according to a study presented at the 2016 annual meeting of the American Society for Radiation Oncology.
The combination of adjuvant bevacizumab and capecitabine failed to improve disease-free survival compared with capecitabine alone in patients with mCRC who had undergone potentially curative surgery.
A twenty percent decrease in cancer death rate among children and adolescents has taken place from 1999 to 2014.
Minimal residual disease (MRD) negativity after treatment is associated with prolonged overall survival in patients with newly diagnosed multiple myeloma.
An analysis of population trends in England demonstrated that use of electronic cigarettes improves the rate of successful quit attempts, but results in less use of prescription nicotine-replacement therapy products.
Early care after an incurable cancer diagnosis improves quality of life and also increases the chances of having end-of-life discussions.
Palliative care improved quality of life, depression, anxiety, and symptom burden in patients with hematologic malignancies hospitalized for hematopoietic stem cell transplantation (HCT).
Smartphones can motivate patients to stay on track with lifestyle changes.
Hematopoietic stem cell transplantation (HCT) is found to increase expression of a genetic code used to make proteins, leading to a biological aging of immune cells equivalent to 30 years of chronological age.
[Journal of Gastrointestinal Oncology] This research examines factors associated with survival in patients with brain metastasis from esophageal cancer.
The population-based EUTOS registry demonstrated high overall and progression-free survival rates among patients with chronic myeloid leukemia.
HIV is associated with reduced cancer-specific survival among women with invasive cervical cancer.
African American survivors of breast cancer experience significant problem burden during the first 5 years after diagnosis and treatment.
Lifestyle and dietary measures for preventing colorectal cancer are extensively studied; however, in this study, researchers looked at a dietary measure that improved survival for patients after diagnosis.
When patients ask about safety and using e-cigarettes to stop smoking, doctors give varying advice.
Adult survivors of childhood cancer are at increased risk for late adverse pulmonary events.
Cancer survivors who are nonwhite, less educated, older, and/or have comorbidities were less likely to receive adequate cancer pain management.
Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma
[OncoTargets and Therapy] This research reviews the effects of single-port access transaxillary totally endoscopic thyroidectomy on outcomes following surgery, including quality of life and cosmetic result, in patients with papillary thyroid carcinoma (PTC).
Older cancer survivors' self-reports of sexual activity and functioning are comparable to age-matched people without cancer; despite this, sexual dissatisfaction is more prevalent among cancer survivors than age-matched cancer-free persons.
Addition of Elotuzumab to Bortezomib/Dexamethasone Improves Survival in Relapsed/Refractory Multiple Myeloma
The addition of elotuzumab to bortezomib/dexamethasone appears to increase progression-free survival in relapsed/refractory multiple myeloma (RRMM).
Younger cancer survivors in Norway were more likely to be financially dependent and unemployed than individuals without cancer.
Patients with metastatic non-small cell lung cancer demonstrated prolonged median progression-free survival with the administration of erlotinib below the maximum tolerated dose.
Research indicates that metformin can confer improved survival for patients with colorectal cancer that also have diabetes.
Treatment with daratumumab, lenalidomide, and dexamethasone (DRd) may be superior to lenalidomide and dexamethasone (Rd) alone in patients with relapsed or refractory multiple myeloma.
Dasatinib and nilotinib are associated with similar response rates and survival outcomes in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP).
Insurance status influences overall patient survival for some cancer types, but its impact on glioblastoma multiforme (GBM) survival is well documented. This research study explored the possible impact of insurance on GBM survival.
Use of androgen suppression therapy may negatively impact survival in African American patients with favorable-risk prostate cancer.
Survival among women age 40 years and younger with breast cancer appears to vary according to breast cancer subtype, with age particularly prognostic for women with luminal type breast cancers.
A recent study examined the possible correlation between Medicaid coverage status and overall survival for patients with head and neck cancer.
As salvage radiotherapy (SRT) outcomes may be affected by factors associated with prostatectomy findings, they may be positively affected when used at lower prostate-specific antigen (PSA) levels.
Acupressure reduced persistent fatigue in women who had been treated for breast cancer, improving both sleep and quality of life.
Choosing no treatment and regular check-ups didn't seem to stress men with low-risk disease
Low aerobic capacity has greater effect on longevity than even high cholesterol, or high blood pressure.
Tyrosine Kinase Inhibitor Therapy Can Be Safely Stopped in Select Patients With CML in Chronic Phase
A high percentage of patients with CML treated with TKIs achieve deep molecular responses and can safely stop therapy. Initials results of the EURO-SKI trial define prognostic markers that indicate durability of deep molecular responses after stopping TKI therapy.
Systematic Palliative Care Provides Greater Improvement in Quality of Life for Patients with Pancreatic Cancer
Quality of life is significantly improved for patients with pancreatic cancer when systematic palliative care is administered vs on-demand palliative care.
A very large retrospective study of patients with stage II colon cancer found adjuvant therapy improves survival, regardless of treatment regimen, patient age, or high-risk pathologic risk features.
Although most adolescent survivors of childhood cancer have no reported psychological symptoms, those who do often have multiple symptoms and distinct symptom profiles.
Telomere length is predictive for determining which children treated for AML are at highest risk for delayed recovery, a finding that may have significant implications for treatment-related morbidity and mortality.
Improved cancer detection and advances in treatment mean larger numbers of older cancer patients are becoming survivors, combined with demographic trends. But older patients are underrepresented in clinical trials.
In addition to improving overall survival compared with dacarbazine in patients with advanced melanoma, nivolumab maintains baseline levels of health-related quality of life to ultimately confer long-term quality of survival benefit.
In a large cohort of hematologic oncologists surveyed in the United States, standard end-of-life quality measures were highly acceptable, but unrealistic patient expectations are the greatest impediment to quality end-of-life care.
Memory problems in breast cancer survivors appear associated with the high stress load these patients experience rather than their treatment, and moderate-to-vigorous physical activity may help subjective memory in these patients.
Lung cancers that manifest as nonsolid nodules seem to have indolent course, according to recent research data.
Relaxing acupressure resulted in significant improvement in persistent fatigue, sleep quality, and quality of life among survivors of breast cancer, a recent study has shown.
The Patient-Owned Survivorship Transition Care for Activated, Empowered survivors (POSTCARE) intervention resulted in clinically meaningful improvements in 3 domains of quality of life (QoL) among survivors of breast cancers.
A group of researchers sought to examine the physical functioning of patients with breast cancer, in various age brackets, who were enrolled in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) phase III trial.
Likelihood of other chronic conditions will stress health care system in next two decades, as more patients with cancer live longer.
Nearly 1 in 12 patients with a cancer from the 10 most common cancer sites developed a second primary neoplasm during survivorship.
Many Older Women With Early Stage Breast Cancer Are Susceptible to Functional Decline After Starting Treatment
Approximately 20% of older women with stage I-III breast cancer lost the ability to complete some basic tasks of independent living within 1 year of starting treatment. However, an assessment tool can identify those women at greatest risk of posttreatment functional decline.
Gross total resection to treat glioblastoma multiforme (GBM) showed progression-free survival benefits over subtotal resection and biopsy in a meta-analysis of 37 studies.
Recent results from a multicenter, phase 2 trial suggest that patients with HIV and aggressive lymphoma should receive autologous stem cell transplant as standard of care. Risk of serious complications after transplant in these patients is equal to that of patients without HIV.
Undergoing pleurectomy and decortication for malignant pleural mesothelioma generally leads to improved quality of life after the surgery.
Cancer and dementia patients get more access to palliative care than do patients with many other chronic conditions, recent research indicates.
Ibrutinib treatment for chronic lymphocytic leukemia with the deletion of chromosome 17p (del17p CLL) increases the percentage of patients alive at 30 months over other therapies for del17p CLL.
In a randomized phase III study of the drug inotuzumab ozogamicin, a statistically significant percentage of patients with ALL whose disease had relapsed following standard therapies, qualified for stem cell transplants after treatment with the drug.
Event-free survival for adult patients with ALL has improved from 40% to 73% with the implementation of the NOPHO ALL 2008 protocol in July 2008.
Adjuvant chemotherapy in patients with stage Ib non-small cell lung cancer improved overall survival and 5-year overall survival.
The number of patients older than 75 years who do not undergo surgery is increasing, especially among those with stage III or IV ovarian cancer. Approximately 50% do not undergo surgery and 25% receive no treatment at all.
New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases
Researchers demonstrate how breast cancer cells invade bone marrow, where they escape chemotherapy and hormonal therapies that would otherwise eliminate the cancer cells.
Metastatic capabilities of pancreatic cancer might arise before tumors even form. Metastasis and advanced stage of disease at diagnosis are attributed to low survival rates for pancreatic cancer.
A post-hoc analysis of the Phase 3 ASPIRE study indicates that treatment combining carfilzomib with lenalidomide and dexamethasone extended survival time for patients with multiple myeloma.
Biochemical Marker Is a Better Predictor of Adverse Effects in Patients with Non-small Cell Lung Cancer
Albumin concentration with an established cutoff point is proven a better predictor of both chemotherapy toxicity and survival in patients with advanced lung cancer.
- Ruxolitinib May Improve Symptom Control in Patients With CLL
- 3-drug Regimen With Ricolinostat Active, Safe in Multiple Myeloma
- Lung Cancer Navigator App Aims to Help Patients Understand Disease
- Racial Disparities Persist in Myeloma Treatment Use
- Adding Bortezomib to Rd Improves PFS, OS in Newly Diagnosed Myeloma
- Optimal Timing of Influenza Vaccination in Patients Receiving Chemotherapy
- Racial Disparities Persist in Myeloma Treatment Use
- Hypnosis and Its Use in Cancer Treatment
- Longer Dosing Interval of Zoledronic Acid May Be Acceptable for Bone Metastases
- Melanoma Incidence Still on the Rise in Parts of the United States
- Frailty Classifications Associated With Prognosis Among Older Patients
- Beach Umbrella Not Enough for Protection from UV Rays
- Comprehensive Report Looks at Benefits and Harms of Medical Cannabis
- ASCO: Moderate Activity Linked to Longer Survival in Advanced CRC
- MABp1 Improves Symptoms vs Placebo in Colorectal Cancer
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