Surgical Resection

Imaging and Fluorescence Technique Guides Surgical Removal of Otherwise Undetectable Ovarian Tumors

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A newly created tumor-specific fluorescent molecule combined with an imaging system guided surgeons to removing additional tumors not palpable or visible without fluorescence in patients with ovarian cancer.

Surgical Probe Distinguishes Between Tumor Margins and Healthy Tissue

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A new surgical tool that uses light to ensure surgeons removed all of a cancerous tumor was found to correlate well with traditional pathologists' diagnoses, according to a clinical study showing that the tool could soon enable reliable, real-time surgical guidance.

Targeted molecular contrast agent may improve visualization of lung tumor margins

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New molecular tools are emerging to identify lung adenocarcinomas during pulmonary resection. The results of a proof-of-concept study suggest that fluorescent imaging of lung cancer during surgery using targeted molecular agents may soon be a reality.

Tool successfully distinguishes between breast cancer and normal tissues

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Researchers have successfully tested a new tool that will help surgeons better distinguish cancerous breast tissue from normal tissue, which should lower the mount of repeat procedures needed.

Study compares treatment risks for early esophageal cancer

Study compares treatment risks for early esophageal cancer

A new study sheds new light on the risks associated with the growing popularity of endoscopic resection in the treatment of localized, early-stage esophageal cancer.

Colorectal cancer resection mortality still high for elderly

Colorectal cancer resection mortality still high for elderly

Despite an overall improved mortality seen during the past 10 years, advancing age is associated with higher morbidity and mortality in colorectal cancer resection.

ACS: Laparoscopic colon cancer resection advantageous for elderly

ACS: Laparoscopic colon cancer resection advantageous for elderly

Laparoscopic procedure linked with lower risk of discharge to a nursing facility when compared with open surgery.

Carbon ion radiotherapy works for inoperable spinal sarcomas

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Carbon ion radiotherapy (CIRT) appears to be safe and effective for the treatment of persons with unresectable spinal sarcoma, researchers have affirmed.

Lung cancer pathology pattern may predict cancer recurrence after surgery

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A specific pattern found in the tumor pathology of some patients with lung cancer is a strong predictor of recurrence, according to a new study.

Locally advanced pancreatic cancer responds to FOLFIRINOX

FOLFIRINOX chemotherapy plus chemoradiation helped make resection possible in locally advanced pancreatic cancer.

Cetuximab enables liver metastasis surgery in colorectal cancer

Combining cetuximab (Erbitux) with standard therapy improved the resectability of previously inoperable liver metastases of colorectal cancer.

New type of retinoblastoma discovered in babies

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A new type of retinoblastoma, which is a rapidly developing eye cancer that affects very young babies, has been discovered. This finding can immediately change clinical practice and optimize care for these children.

5-ALA fluorescence guide improves resection of glioblastoma multiforme

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Fluorescence form 5-aminolevulinic acid (5-ALA) has been used to guide resection of recurrent GBM. Before surgery, the patient ingests 5-ALA, then the tumor cells fluoresce intraoperatively in response to certain wavelengths of light.

EGFR doesn't predict outcomes in lung cancer

EGFR mutation is not a prognostic factor in non-small cell lung cancer, but EGFR tyrosine kinase inhibitors may prolong survival after recurrence.

Treatment outcomes compared in early-stage lung cancer

In early non-small cell lung cancer, overall survival was better after surgery than after radiation, but cancer-specific survival was similar.

Fluorescence provides instant pathology of lymph nodes during surgery

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A new technique has been developed that allows surgeons, during surgery, to identify which lymph nodes are cancerous so that healthy tissue can be saved.

"ICE" is key to new kidney-sparing cancer surgery

A surgical technique known as intracorporeal cooling and extraction (ICE) may reduce the need for conventional open surgery in kidney cancer.

Adjuvant chemotherapy increases survival rates after resection of recurrent breast cancer

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Chemotherapy after surgery led to higher rates of disease-free and overall survival for women with isolated local or regional recurrence of breast cancer.

Regorafenib prolongs survival in face of GI cancers

Persons with metastatic colorectal cancer or gastrointestinal stromal tumors may garner some survival benefit from regorafenib after standard treatments have failed.

Four studies report on advances and challenges in improving the quality of cancer care

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New studies reveal important advances in cancer care quality measurement, physician adherence to quality standards, and end-of-life care, while highlighting the overuse of contralateral prophylactic mastectomy.

Repeat glioblastoma surgeries may prolong life

Persons with glioblastoma who undergo repeated resections can have improved survival, indicate the findings of a recent study.

Early surgery for low-grade gliomas better than waiting

A facility favoring early surgical resection of low-grade glioma had better overall survival rates than did a facility favoring watchful waiting.

Higher risk of uterine cancer recurrence when radiation therapy after hysterectomy is delayed

The risk of uterine cancer recurrence may be increased by waiting too long after a hysterectomy to begin radiation therapy. For patients with uterine cancer who are not receiving chemotherapy, tumors were found to be more likely to return if radiation therapy was delayed 9 weeks or longer following surgery.

"LESS" painful form of laparoscopy proven in kidney cancer

Laparoendoscopic single-site surgery (LESS) for removal of a cancerous kidney led to a less painful recovery than did traditional multiport laparoscopy.

Patients with colorectal or bladder cancer may benefit from advanced surgical approaches

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Robotic-assisted operations and minimally invasive surgical procedures may extend survival and improve recovery in these patients compared with conventional open operations, according to recent studies presented at the 2012 Annual Clinical Congress of the American College of Surgeons.

Preop pain brings on postop pain in breast cancer

Women with chronic preoperative pain were up to three times more likely to report moderate to severe pain on movement after breast cancer surgery.

Multiple tumors worsen glioblastoma prognosis

Persons with more than one glioblastoma tumor upon diagnosis experience significantly worse survival than do patients with a solitary lesion.

Quantity/quality of life in pancreatic cancer examined

Knowing how much time people with pancreatic cancer spend in the hospital or in medical care can help clinicians make treatment recommendations.

"Inoperable" pancreatic cancer may be treatable after all

"Inoperable" pancreatic cancer may be treatable after all

Oncologists at M.D. Anderson Cancer Center found the key to screening for pancreatic cancer lies in the interpretation of preoperative CT scans.

Assay can predict survival

Assay can predict survival

A new molecular test is more accurate at predicting high risk for death after surgical resection of early-stage nonsquamous NSCLC.

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