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SULAR
Hypertension
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Drug Name:

SULAR Rx

Generic Name and Formulations:
Nisoldipine 8.5mg, 17mg*, 34mg; ext-rel tabs; *contains tartrazine.

Company:
Covis Pharmaceuticals, Inc.

Therapeutic Use:

Indications for SULAR:

Hypertension.

Adult:

Swallow whole. Take on an empty stomach (1hr before or 2hrs after a meal). Initially 17mg once daily; may increase by 8.5mg per week or longer intervals. Usual maintenance: 17–34mg once daily; max 34mg/day. Hepatic impairment or elderly (>65yrs): Initially 8.5mg once daily.

Children:

Not established.

Warnings/Precautions:

Coronary artery disease. Heart failure or compromised ventricular function (esp. with a beta-blocker). Monitor BP closely during initiation and titration. Severe hepatic impairment. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Avoid concomitant CYP3A4 inhibitors or inducers, grapefruit juice. High-fat meals increase peak drug concentrations. Antagonized by phenytoin (avoid; consider alternatives). May be potentiated by cimetidine.

Pharmacological Class:

Calcium channel blocker (CCB) (dihydropyridine).

Adverse Reactions:

Peripheral edema, headache, dizziness, pharyngitis, vasodilation, sinusitis, palpitations, chest pain, nausea, rash; increased angina, MI (rare), hypotension.

How Supplied:

Tabs—100

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