Staging

CT-Based Technique for Body Mass Measurements of Patients With Cancer Improves Disease Staging, Therapy Monitoring

CT-Based Technique for Body Mass Measurements of Patients With Cancer Improves Disease Staging, Therapy Monitoring

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A new method of measuring lean body mass accounts for changes in body composition, enabling improved disease staging and monitoring of therapy.

Biomarker for Class 1 Uveal Melanoma Correlates with Metastatic Disease

Biomarker for Class 1 Uveal Melanoma Correlates with Metastatic Disease

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A new biomarker measurement might improve the accuracy of prognostic testing and precision medicine in uveal melanoma.

Staging by Lymph Node Categories Shown to Better Predict Survival in Patients With Oropharyngeal Cancer

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The current staging system for oropharyngeal cancer does not adequately differentiate HPV-positive from HPV-negative OPC. These researchers suggest regional OPC lymph node (N) categories and nasopharyngeal N categories might be more useful in staging HPV-positive OPC.

Tumor Weight and Volume May Improve Mesothelioma Staging Accuracy

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Improvements in scoring the severity of mesothelioma could be achieved by considering both tumor weight and volume.

Node-related Upstaging of Lung Cancer Occurs More Often With Open vs Closed Procedures

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Non-small cell lung cancer stage is increased due to discovering a lymph node positive for cancer more often following open chest surgery, compared with closed surgery.

Affordable Care Act (ACA) Impacts Stage at Diagnosis and Fertility-Sparing Treatment in Young Women With Cervical Cancer

Affordable Care Act (ACA) Impacts Stage at Diagnosis and Fertility-Sparing Treatment in Young Women With Cervical Cancer

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Both the stage of cervical cancer at diagnosis and the receipt of fertility-sparing treatment among young women age 21 to 25 years, but not among women age 26 to 34 years, is associated with the Affordable Care Act Dependent Coverage Expansion provision.

FDG PET/CT not useful in staging newly diagnosed stage III invasive lobular breast cancer

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Although FDG PET/CT is appropriate for systemic staging of newly diagnosed stage III breast cancer, the technique may not be equally valuable for all breast cancer histologies, research indicates.

Cancer Staging (Fact Sheet)

Cancer Staging (Fact Sheet)

This fact sheet explains cancer staging, the TNM System, and tests commonly used to determine cancer stage.

Quality of biopsy directly linked to survival in patients with bladder cancer

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Researchers have demonstrated for the first time that the quality level of diagnostic staging using biopsy in patients with bladder cancer is directly linked with their survival.

Breast cancer is more accurately diagnosed after PET/CT imaging in younger patients

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A change in diagnosis resulted from PET/CT imaging of patients who were younger than 40 years with an initial diagnosis of stage I-III breast cancer, according to a retrospective analysis.

Lung cancer diagnosis tool safe and effective for older patients

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A recent study has found that a procedure to take tissue samples from lung cancer patients can be used safely in the elderly. This allows doctors to make a more accurate diagnosis and to choose appropriate treatment.

Update of staging criteria for breast cancer diagnosis recommended

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New findings paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin, but not beyond.

Mammography has led to fewer late-stage breast cancers

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In the 30 years since mammography was introduced, late-stage breast cancer incidence has decreased by 37%, according to a new study. The analysis, from the University of Michigan Comprehensive Cancer Center in Ann Arbor, takes into account an observed underlying trend of increased breast cancer incidence present since the 1940s

Researchers suggest updating the staging criteria for breast cancer diagnoses

Researchers suggest updating the staging criteria for breast cancer diagnoses

Study findings from Fox Chase Cancer Center offer relatively optimistic news for women with breast cancer whose disease has spread to the chest wall or skin, but not beyond.

Microfluidic chip improves detection of circulating tumor cells

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A device is being created to monitor circulating tumor cells (CTCs), with the ability to easily retrieve the cells for further testing. The ability to detect CTCs in this way can play an important role in early diagnosis and treatment monitoring.

Simple blood test can indicate cervical cancer

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The heat profile from a person's blood, known as a plasma thermogram, can serve as an indicator for the presence or absence of cervical cancer, including the stage of the cancer.

New diagnostic and therapeutic techniques for patients with metastasized melanoma

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New research highlights the potential of newly developed radiopharmaceuticals with benzamide for the imaging of metastases and as a targeted systemic therapy.

Staging is overused in younger, early-stage breast cancer patients

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More than one-third of younger, early-stage breast cancer patients undergo unnecessary imaging procedures at the time of staging and diagnosis, according to research presented at the 2013 San Antonio Breast Cancer Symposium.

Guidelines cover diagnosis, staging of esophageal cancer

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The Society of Thoracic Surgeons (STS) has released new clinical-practice guidelines that feature evidence-based recommendations to help clinicians diagnose and stage esophageal cancer.

Immunocytochemistry used to determine ALK status in lung cancer

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ALK immunocytochemistry is highly accurate for detecting ALK-rearranged non-small cell lung cancer (NSCLC) on cytological specimens, according to newly published research.

Lymphoseek detects more sentinel lymph nodes than standard blue dye

The new radiopharmaceutical, technetium Tc99m tilmanocept (Lymphoseek), improves sentinel lymph node mapping in breast cancer.

Lung cancer survival based on more than stage at diagnosis

Data show that differences in stage at diagnosis explain some but not all of the international variation in overall lung cancer survival.

International disparity in stage-specific lung cancer survival

International disparity in stage-specific lung cancer survival

Net survival from TNM stage I and IV disease, 16 and 10 percent lower in UK versus Sweden.

Longer delays in breast cancer treatment may affect survival

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Delays between a breast cancer diagnosis and treatment increase the risk of death for women with late-stage cancers, according to a recently published study. A second study found that the median wait time between diagnosis and treatment has grown longer.

Cancer diagnosis through automatic mitotic cell detection

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The system promises to bring objectivity and automation to the cancer grading process, which determines the aggressiveness of the treatment offered to the patient.

Measuring water in breast tissue may prevent unnecessary biopsies

Assessing how water moves through breast tissue may reduce false-positive findings among women undergoing dynamic contrast-enhanced MRI.

Older age marker may be a more appropriate predictor of prognosis in papillary thyroid cancer

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Younger age at diagnosis is no longer a useful predictor of negative outcomes in the staging of patients with papillary thyroid cancer. Prognosis for survival in thyroid cancer does not drop until age 65 to 74 years, and those patients still have 92.0% survival.

Breath test can indicate lung cancer

An analysis of breath samples from patients with pulmonary nodules distinguished benign from malignant growths in a recent study.

Pre-op SPECT/CT detected more lymph node metastasis in melanoma

Preoperative imaging detected more positive sentinel lymph nodes and improved disease-free survival among patients with cutaneous melanoma.

"Inoperable" pancreatic cancer may be treatable after all

"Inoperable" pancreatic cancer may be treatable after all

Oncologists at M.D. Anderson Cancer Center found the key to screening for pancreatic cancer lies in the interpretation of preoperative CT scans.

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