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SPECTRACEF
Bacterial infections
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Drug Name:

SPECTRACEF Rx

Generic Name and Formulations:
Cefditoren (as pivoxil) 200mg, 400mg; tabs.

Company:
Vansen Pharma Inc.

Therapeutic Use:

Indications for SPECTRACEF:

Susceptible mild to moderate acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia (CAP), pharyngitis/tonsillitis, uncomplicated skin and skin structure infections.

Adult:

Take with meals. Bronchitis: 400mg twice daily for 10 days. CAP: 400mg twice daily for 14 days. Pharyngitis/tonsillitis, skin and skin structure: 200mg twice daily for 10 days. Renal impairment (CrCl 30–49mL/min): max 200mg twice daily; CrCl <30mL/min: max 200mg once daily; ESRD: not established.

Children:

Not established.

Contraindications:

Milk protein allergy (not lactose intolerance). Carnitine deficiency or conditions causing carnitine deficiency.

Warnings/Precautions:

Penicillin or other allergy. Not for long-term therapy. Decreased muscle mass (risk of carnitine deficiency). Monitor prothrombin time in renal or hepatic impairment or poor nutritional state. Labor & delivery. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Avoid drugs that reduce gastric acidity. Potentiated by probenecid. May cause false (+) glucose test with Clinitest, Fehling's or Benedict's soln, Coomb's test; false (–) with ferricyanide test.

Pharmacological Class:

Cephalosporin.

Adverse Reactions:

GI upset, headache, transient reduction in plasma carnitine levels; pseudomembranous colitis.

Elimination:

Renal.

Generic Availability:

NO

How Supplied:

Tabs (200mg)—20-count blister pack; 400mg—2-, 20-, 28-count blister pack

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