A newly developed, evidence-based psychoeducational intervention effectively reduced fear of cancer recurrence and stress in patients at high risk for developing another melanoma.
Organ transplant recipients of all races/ethnicities are at higher risk for skin cancer, therefore routine, annual total-body skin cancer screenings should be a part of post organ transplant care.
Treatment with pembrolizumab better maintained health-related quality of life compared with chemotherapy in patients with advanced melanoma refractory to ipilimumab.
[OncoTargets and Therapy] This research presents a rare case of a secondary tumor (BCC) which arose on top of a primary tumor (keloid scar) on the right auricle region in a healthy 23-year-old woman.
Patients with localized melanoma see their supportive care needs peak at their initial cancer diagnosis and if they experience disease recurrence.
Three-quarters of young adult women who visit indoor tanning salons support stronger restrictions on their use.
Response rates with PD-1 inhibitors in patients with acral and mucosal melanomas were similar to previously reported rates in patients with cutaneous melanoma.
Variants of the MC1R gene, associated with red hair, pale skin, and freckles, increases the number of genetic mutations related to skin cancer and the level of other gene mutations, further increasing the risk for skin cancer.
Cobimetinib in combination with vemurafenib as a standard first-line approach improves survival in patients with BRAF V600 mutation-positive melanoma, updated results of the coBRIM study.
New report doesn't change Task Force's prior statement on skin cancer screening issued in 2009
Training Primary Care Providers to Screen for Melanoma Increases Diagnoses, With Little Affect on Dermatology Visits or Skin SurgeriesJuly 21, 2016
Training primary care providers (PCP) to detect early melanoma led to increased melanoma diagnoses, but had little impact on skin surgeries or dermatology visits.
De novo melanomas, which arise from clinically normal skin with no associated nevus, may be more aggressive than nevus-associated melanomas.
In addition to improving overall survival compared with dacarbazine in patients with advanced melanoma, nivolumab maintains baseline levels of health-related quality of life to ultimately confer long-term quality of survival benefit.
Exaggerated sensitivity to harmless light, or photosensitization, is often triggered by photodynamic therapy used to treat precancerous skin lesions and skin cancers.
Population-based screening for melanoma performed by primary care providers does not cause substantial harm with respect to skin surgeries and dermatology visits.
Results from a clinical trial indicate that 2 topical creams compared favorably to photodynamic therapy for primary, low-risk superficial basal cell carcinoma.
Disease-Free Status Is Achieved by Combining Immunotherapy Treatments in Patient With Metastatic MelanomaJune 17, 2016
A patient with refractory metastatic melanoma was successfully treated with a novel combination of 2 different types of immunotherapy.
Cutaneous melanoma is rare on feet, but often advanced at point of diagnosis.
Pembrolizumab provides benefit over ipilimumab in patients with advanced melanoma, regardless of tumor PD-L1 expression status or number of prior therapies, a study presented at the 2016 ASCO Annual Meeting has shown.
A newly discovered synthesized drug reduced the viability of melanoma cells without affecting normal cells in cell culture and mouse xenograft models of the disease. The drug, HA15, is a type of thiazole benzenesulfonamide.
Combining radiation treatments with a new generation of immunotherapies is showing promise in the treatment of melanoma, according to a recent review.
To improve patient comfort during full-body skin cancer screenings, dermatologists should respect patients' preferences for the gender of the examining clinician and for how the genital area is examined.
The Bim protein might predict which patients could be successfully treated with immunotherapy for metastatic melanoma.
New study highlights the importance of diagnosing and treating obstructive sleep apnea because of possible cancer connection.
The geometric shape of the outside edge of a cancerous tumor plays a significant role in activating tumor-seeding cells that lead to metastasis.
[Cancer Control] This research explores the efficacy of intralesional therapy as a treatment option for patients with unresectable, locally advanced, or metastatic melanoma.
Half of 25 patients with Merkel cell carcinoma treated with pembrolizumab experienced significant tumor shrinkage that lasted almost 3 times longer than conventional chemotherapy, and some had no remaining disease after treatment.
Overall objective responses occurred in one-third of patients with melanoma who were treated with pembrolizumab in a phase 1b clinical trial.
Aggressive basal cell skin cancers have higher levels of both EZH2 and Ki67, suggesting these proteins have potential to serve as biomarkers for when basal cell carcinoma has become dangerous.
Melanoma onset was delayed by applying sun protection factor 30 (SPF30) sunscreen prior to exposure to ultraviolet-B light in a mouse model of the disease.
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