Skin Cancer

Study Finds Association Between Folate Intake and Risk of Cutaneous Melanoma

Study Finds Association Between Folate Intake and Risk of Cutaneous Melanoma

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Researchers assessed the effect intake levels of folate and other nutrients involved in one-carbon metabolism have on risk of melanoma.

Melanoma Outcomes Improved With Nivolumab Alone or Plus Ipilimumab

Melanoma Outcomes Improved With Nivolumab Alone or Plus Ipilimumab

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Systemic review and meta-analysis evaluated the efficacy of nivolumab vs ipilimumab, in combination, as monotherapy, or vs other treatment options for the treatment of metastatic melanoma.

Oral Contraceptive Use May Not Be Associated With Increased Melanoma Risk

Oral Contraceptive Use May Not Be Associated With Increased Melanoma Risk

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Researchers sought to determine if melanoma risk was associated with oral contraceptive use or if OC users are more likely to have higher exposure to UV light.

Encorafenib, Binimetinib Combination Receives FDA Approval for Mutation-Positive Melanoma

Encorafenib, Binimetinib Combination Receives FDA Approval for Mutation-Positive Melanoma

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Approval was granted for the treatment of patients with unresectable or metastatic BRAF V600E or V600K mutation-positive melanoma.

Radiation, Immunotherapy Improved Median Overall Survival in Melanoma Brain Metastases

Radiation, Immunotherapy Improved Median Overall Survival in Melanoma Brain Metastases

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Study data indicate that checkpoint inhibitors combined with radiation could improve survival for patients with melanoma-related brain metastases.

New Guidelines Increase Melanoma Staging Reproducibility and Concordance

New Guidelines Increase Melanoma Staging Reproducibility and Concordance

Greater reproducibility and higher concordance for melanoma staging observed with implementation of AJCC 8.

Link Found Between Skin Cancer Risk and High Polyunsaturated Fat Intake

Link Found Between Skin Cancer Risk and High Polyunsaturated Fat Intake

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Using data from the NHS and the HPFS, researchers investigated the association between polyunsaturated fat, cholesterol, and monounsaturated fat intake and risks for SCC, melanoma, and BCC.

Lower Risk for Alzheimer Associated With Skin Cancer Diagnoses

Lower Risk for Alzheimer Associated With Skin Cancer Diagnoses

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After adjusting for confounding factors,a significantly decreased risk for subsequent AD was reported among patients with malignant melanoma.

New Recommendations Target Promoting Better Sun Protection Habits for All Patients

New Recommendations Target Promoting Better Sun Protection Habits for All Patients

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A new US Preventive Services Task Force Evidence Report is suggesting that greater efforts are needed to educate children and young adults with fair skin about risks of sun exposure. Although the Task Force recommendations are directed at primary care, its members are encouraging oncology nurses to take note of these new findings.

What Prompts Indoor Tanners and Nontanners to Undergo Skin Cancer Screening?

What Prompts Indoor Tanners and Nontanners to Undergo Skin Cancer Screening?

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Researchers sought to determine the factors that influenced a decision to undergo skin cancer screening among more than 30,000 adults who have ever used an indoor tanning device and nontanners.

Study Determined Association Between Risk of Melanoma, Aspirin Use

Study Determined Association Between Risk of Melanoma, Aspirin Use

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In a review of nearly 200,000 patients from a Midwest metropolitan area, researchers sought to determine if chronic aspirin use would offer the same risk reduction for melanoma as has been seen in various cancers.

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

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Investigators sought to compare the prognostic value of sentinel lymph node status vs Breslow thickness in patients with cutaneous melanoma.

USPSTF: Skin Cancer Counseling Recommended for Fair-Skinned Individuals

USPSTF: Skin Cancer Counseling Recommended for Fair-Skinned Individuals

The U.S Preventive Services Task Force recommends counseling for fair-skinned individuals younger than 24 years, and selective counseling is recommended for adults.

USPSTF: Behavioral interventions do not reduce sunburn or skin cancer outcomes

1. Behavioral interventions increase sun protection behavior but do not reduce sunburn or skin cancer outcomes. 2. Behavior interventions lead to increased skin self-examinations but may lead to additional skin procedures without finding additional skin cancers. Evidence Rating Level: 1 (Excellent) Study Rundown: While melanoma comprises 2% of all skin cancers, it causes more than []

Presence of Iris Pigmented Lesions Indicates Melanoma Risk

Presence of Iris Pigmented Lesions Indicates Melanoma Risk

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The likelihood for development of cutaneous melanoma may be greater for individuals with iris pigmented lesions, according to a study.

Revised AJCC8 Demonstrates Superior Tumor Classification for HNCSCC 

Revised AJCC8 Demonstrates Superior Tumor Classification for HNCSCC 

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AJCC8 tumor classification demonstrated significantly superior homogeneity and monotonicity to AJCC7 tumor classification.

Age Not a Deterrent to Immunotherapy for Malignant Melanoma

Age Not a Deterrent to Immunotherapy for Malignant Melanoma

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Investigators sought to evaluate whether age is associated with risk for immune-related adverse events among patients with metastatic melanoma treated with immunotherapy.

Adjuvant Vemurafenib Does Not Improve Disease-Free Survival in Melanoma

Adjuvant Vemurafenib Does Not Improve Disease-Free Survival in Melanoma

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Researchers report on finding of a double-blind phase 3 study on the efficacy of adjuvant vemurafenib in patients with resected stage IIC to IIIB melanoma.

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

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A retrospective study evaluated the relationship of BMI with survival outcomes among patients with metastatic melanoma who received targeted therapy, immunotherapy, or chemotherapy.

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

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The FDA granted approval for nivolumab for adjuvant treatment of some patients with melanoma, based on the results of the CHECKMATE-238 study.

Potential for Metastatic Melanoma Cure Seen in High CR Rate With Pembrolizumab

Potential for Metastatic Melanoma Cure Seen in High CR Rate With Pembrolizumab

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Baseline tumor size and PD-L1 status were independently associated with the likelihood of a complete response.

Distinct Patterns of Shiny White Streaks Strong Indicator of Melanoma

Distinct Patterns of Shiny White Streaks Strong Indicator of Melanoma

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Patients presenting with lesions with shiny white streaks on dermoscopy should undergo biopsy for possible melanoma.

Adherence to Skin Cancer Screening Guidelines Beneficial in Management SCC in SOTRs

Adherence to Skin Cancer Screening Guidelines Beneficial in Management SCC in SOTRs

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Transplant recipients developed squamous cell carcinomas that did not appear to behave more aggressively than those that developed in the immunocompetent group.

Fluorouracil Associated With Reduced Surgery for Squamous Cell Carcinoma

Fluorouracil Associated With Reduced Surgery for Squamous Cell Carcinoma

A reduced risk of squamous cell carcinoma, but not basal cell carcinoma, was observed for one year in at-risk individuals treated with fluorouracil.

Atopic Dermatitis Linked to Increased Risk of Skin Cancer

Atopic Dermatitis Linked to Increased Risk of Skin Cancer

Individuals with a history of atopic dermatitis have a higher risk of squamous cell carcinoma development, research indicates.

No Increased Risk for Melanoma in Patients With MM

No Increased Risk for Melanoma in Patients With MM

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An increased prevalence of melanoma has been observed in patients with various immunocompromised conditions.

Researchers Find No Link Between Acne and Malignant Melanoma in Men

Researchers Find No Link Between Acne and Malignant Melanoma in Men

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Individuals categorized as overweight or obese had a significantly increased risk for malignant melanoma.

Survival Benefit in Advanced Melanoma With Pembrolizumab Versus Ipilimumab

Survival Benefit in Advanced Melanoma With Pembrolizumab Versus Ipilimumab

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Fifty-five percent of patients treated with pembrolizumab survived through 24-months compared with 43% of patients treated with ipilimumab.

Challenging the Standard of Care in Advanced Melanoma: Focus on Pembrolizumab

Challenging the Standard of Care in Advanced Melanoma: Focus on Pembrolizumab

[Cancer Management and Research] This study examines the advances that pembrolizumab has made in melanoma and upcoming research that may further improve melanoma treatment.

Is This the End of Cytotoxic Chemotherapy in Merkel Cell Carcinoma?

Is This the End of Cytotoxic Chemotherapy in Merkel Cell Carcinoma?

[OncoTargets and Therapy] A review of the role of chemotherapy in the treatment of Merkel cell carcinoma in view of the recent FDA approval of the PD-L1 antibody avelumab and limited and controversial data on the efficacy of chemotherapy in this disease.

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