ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

SIMBRINZA
Glaucoma
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

SIMBRINZA Rx

Generic Name and Formulations:
Brinzolamide 1%, brimonidine tartrate 0.2%; oph susp; contains benzalkonium chloride.

Company:
Alcon Laboratories, Inc.

Therapeutic Use:

Indications for SIMBRINZA:

Reduction of elevated intraocular pressure in open-angle glaucoma or ocular hypertension.

Adults and Children:

<2yrs: contraindicated. ≥2yrs: 1 drop three times daily.

Contraindications:

Neonates and infants <2yrs.

Warnings/Precautions:

Sulfonamide allergy. Discontinue if serious systemic or hypersensitivity reactions occur. Increased risk of corneal edema in patients with low endothelium cell counts. Severe renal impairment (CrCl <30mL/min): not recommended. Hepatic impairment. Severe cardiovascular disease. Depression. Cerebral or coronary insufficiency. Raynaud’s phenomenon. Orthostatic hypotension. Thromboangitis obliterans. Acute angle-closure glaucoma. Remove soft contact lenses before use; may reinsert 15mins later. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Concomitant oral carbonic anhydrase inhibitors: not recommended. Caution with antihypertensives, cardiac glycosides, tricyclic antidepressants, MAOIs. Concomitant high-dose salicylate may produce acid-base and electrolyte alterations. May be potentiated by CNS depressants (eg, alcohol, opiates, barbiturates, sedatives, anesthetics). Separate administration of other oph drugs by ≥5 minutes.

Pharmacological Class:

Carbonic anhydrase inhibitor + alpha-2 agonist.

Adverse Reactions:

Blurred vision, eye irritation, dysgeusia, dry mouth, eye allergy.

How Supplied:

Susp—8mL

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs