Side-effect Management

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

[OncoTargets and Therapy] This research examines the lymphatic flow in the arm following breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphoscintigraphy (LS).

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

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A study using a mouse model to investigate the effect of adding everolimus to cyclophosphamide to slow tumor growth found the drug also preserves fertility.

Exercise and Psychological Interventions Reduce Cancer-Related Fatigue

Exercise and Psychological Interventions Reduce Cancer-Related Fatigue

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A meta-analysis of randomized clinical trials found that exercise, psychological interventions, and the two combined are most effective.

Neurofeedback Reduces Symptoms of Chemotherapy-induced Peripheral Neuropathy

Neurofeedback Reduces Symptoms of Chemotherapy-induced Peripheral Neuropathy

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A type of functional brain training improved the pain, burning, tingling, and loss of feeling associated with CIPN.

Regorafenib Improves Quality-adjusted Survival in Sarcoma

Regorafenib Improves Quality-adjusted Survival in Sarcoma

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In patients with soft tissue sarcoma pretreated with doxorubicin, treatment with regorafenib significantly reduced the risk of progression symptoms or toxicity.

Web-based Symptom Management Improves Symptom Controllability in Ovarian Cancer

Web-based Symptom Management Improves Symptom Controllability in Ovarian Cancer

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Nurse-guided and self-directed web-based symptom management interventions (WRITE Symptoms) improved symptom controllability among women with recurrent ovarian cancer.

Perioperative Pain Control Reduces Need for Postoperative Narcotics After Hysterectomy for Uterine Cancer

Perioperative Pain Control Reduces Need for Postoperative Narcotics After Hysterectomy for Uterine Cancer

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Preoperative intravenous acetaminophen plus local infiltration of LB during hysterectomy and surgical staging of uterine cancer may reduce the need for postoperative narcotics.

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

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Nicotinamide riboside, a type of B3 vitamin, was shown to prevent chemotherapy-induced peripheral neuropathy in an animal-model study.

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

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Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.

Letermovir Reduces CMV Infection, Improves Survival After Stem Cell Transplantation

Letermovir Reduces CMV Infection, Improves Survival After Stem Cell Transplantation

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A novel agent, letermovir, reduced incidence of CMV in patients undergoing stem cell transplantation for hematologic malignancies.

Hematologic Oral Chemotherapy Clinic Reduces Emergency Department Visits

Hematologic Oral Chemotherapy Clinic Reduces Emergency Department Visits

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A hematologic multidisciplinary oral chemotherapy clinic established at a community hospital identified adverse events early and reduced ED visits.

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

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Internet-based cognitive behavioral therapy has positive effects on sexual functioning in breast cancer survivors experiencing sexual dysfunction.

G-CSF May Help Preserve Fertility in Male Patients With Cancer

G-CSF May Help Preserve Fertility in Male Patients With Cancer

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The use of cytokine granulocyte colony-stimulating factor (G-CSF) may help to preserve fertility in male patients with cancer, according to research.

Scalp Cooling Reduces Risk of Chemotherapy-Induced Alopecia

Scalp Cooling Reduces Risk of Chemotherapy-Induced Alopecia

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Risk of chemotherapy-induced hair loss common to breast cancer therapy may be reduced with the use of scalp-cooling device.

Patients With Urologic Cancer Need Psycho-oncologic Support to Manage High Stress

Patients With Urologic Cancer Need Psycho-oncologic Support to Manage High Stress

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Patients with urologic cancer should be offered psycho-oncologic support to manage effects of emotional stressors.

Best Approach to Infection and Tumor Treatment: Contain or Eliminate?

Best Approach to Infection and Tumor Treatment: Contain or Eliminate?

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Using mathematical analysis, researchers identified factors to help determine if containment or the elimination of an infection or tumor, is most effective.

Treatment Outcomes Were Unchanged by Brentuximab Vedotin (BV)-induced Peripheral Neuropathy

Treatment Outcomes Were Unchanged by Brentuximab Vedotin (BV)-induced Peripheral Neuropathy

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Patients who were surveyed reported that the benefits of treatment with BV outweighed its risks.

Müllerian Inhibiting Substance Hormone Protects Ovaries From Chemotherapy Drugs in Mice

Müllerian Inhibiting Substance Hormone Protects Ovaries From Chemotherapy Drugs in Mice

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Müllerian inhibiting substance (MIS) may be employed to protect ovaries from the effects of chemotherapy, according to research done with mice.

Managing Adverse Effects From Oral Kinase Inhibitors in Patients With Hematologic Cancers

Managing Adverse Effects From Oral Kinase Inhibitors in Patients With Hematologic Cancers

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Ibrutinib, idelalisib, ponatinib, and ruxolitinib are each associated with a variety of potential adverse effects and oncology nurses must be aware of these to successfully monitor for them.

Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs

Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs

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Cancer survivors who reported chronic neuropathic pain 5 years after diagnosis were approximately 50% less likely to retain their jobs than those without chronic neuropathic pain.

Emerging Reproductive Technology Holds Great Potential and Risks for Patients, Research

Emerging Reproductive Technology Holds Great Potential and Risks for Patients, Research

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In vitro gametogenesis (IVG) offers hope for patients and survivors coping with disease-related and treatment-induced infertility, as well as providing a potentially unlimited supply of embryonic stem cells. However, legal and ethical issues need to be addressed before its widespread clinical use.

Cannabis Use Becoming More Common Among Older Patients

Cannabis Use Becoming More Common Among Older Patients

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Using data from previous analyses and several state medical cannabis programs, investigators assessed how social attitudes, health issues, and state laws affect the use of cannabis among persons older than 50 years.

Comprehensive Report Looks at Benefits and Harms of Medical Cannabis

Comprehensive Report Looks at Benefits and Harms of Medical Cannabis

Oral cannabinoids can ease chronic pain and chemotherapy-related nausea, but researchers cite risks, as well.

Hypnosis and Its Use in Cancer Treatment

Hypnosis and Its Use in Cancer Treatment

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A cursory look at hypnosis and where it may be used to offer an alternative and side-effect-free management of several aspects of care that can be beneficial to patients with cancer.

Menopause-specific QoL Changes Associated With Chemoprevention Nonadherence

Menopause-specific QoL Changes Associated With Chemoprevention Nonadherence

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A cohort of participants in the MAP.3 trial completed the MENQOL questionnaire, and the findings shed light on the influence of changes in menopause-specific quality of life on aromatase inhibitor adherence in women at high risk for breast cancer.

Diarrhea Common But Manageable With Pertuzumab-containing Regimens

Diarrhea Common But Manageable With Pertuzumab-containing Regimens

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Because treatment with pertuzumab could include adverse events similar to those observed with EGFR antagonists, such as diarrhea, researchers evaluated participants from 3 trials to determine the incidence and severity of diarrhea observed with pertuzumab.

Serum IL-12 May Predict for Chemotherapy-Related Fatigue in Early-Stage Breast Cancer

Serum IL-12 May Predict for Chemotherapy-Related Fatigue in Early-Stage Breast Cancer

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In this study, researchers sought to identify physical, neurocognitive, and serologic markers that may correlate with self-reported fatigue before and after (neo)adjuvant chemotherapy for patients with early-stage breast cancer.

Adding Aprepitant Not Superior to Ondansetron Monotherapy for UA-RINV

Adding Aprepitant Not Superior to Ondansetron Monotherapy for UA-RINV

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Many patients can still experience UA-RINV despite prophylactic therapy; therefore, researchers explored the effectiveness and safety of dual prophylactic therapy with an NK1 receptor antagonist and a 5-HT3 receptor antagonist.

Tissue Factor May Predict for Recurrent VTE in Patients Receiving Anticoagulants

Tissue Factor May Predict for Recurrent VTE in Patients Receiving Anticoagulants

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An evaluation of the association of tissue factor, clinical risk factors, and other biomarkers measured at the time of initial VTE with recurrent VTE helps determine their predictive value for patients at high risk.

Optimal Timing of Influenza Vaccination in Patients Receiving Chemotherapy

Optimal Timing of Influenza Vaccination in Patients Receiving Chemotherapy

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A comparison of administering the influenza vaccine concurrently with chemotherapy with that of administration within the cytopenic period during 3-week chemotherapy cycles determined which schedule was the optimal timing for vaccination administration in this group.

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