Side-effect Management

Multivitamin Use May Reduce Risk of Chemo-Induced Neuropathy

Multivitamin Use May Reduce Risk of Chemo-Induced Neuropathy

Use of multivitamins prior to a breast cancer diagnosis is associated with reduced symptoms of peripheral neuropathy.

Frozen Gloves Reduced Chemotherapy-Induced PN, Improved Quality of Life

Frozen Gloves Reduced Chemotherapy-Induced PN, Improved Quality of Life

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Quality of life for patients with CIPN was improved by wearing frozen gloves during treatment. Researchers reported in an oral presentation at ESMO 2017 Congress that the gloves reduced symptoms even though long-term differences in neuropathy were not observed.

Daratumumab Infusion-Related Reactions Managed by Pre/Postinfusion Medications

Daratumumab Infusion-Related Reactions Managed by Pre/Postinfusion Medications

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Patients with multiple myeloma treated with daratumumab who experience IRRs may easily be managed by administering pre-infusion and postinfusion medications, investigators reported in a presentation at ESMO 2017 Congress.

Adding Thalidomide to Palonosetron, Dexamethasone Reduces CINV

Adding Thalidomide to Palonosetron, Dexamethasone Reduces CINV

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Delayed CINV was improved significantly in patients receiving highly emetogenic chemotherapy for cancer when thalidomide was added to palonosetron and dexamethasone regimen.

Two FDA Approvals Propel CAR T Cell Therapy Into the Limelight

Two FDA Approvals Propel CAR T Cell Therapy Into the Limelight

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The first FDA approval of a CAR T cell therapy is granted for the treatment of B-cell precursor ALL. FDA also approves rheumatoid arthritis medication for the management of cytokine release syndrome, a common and serious adverse effect of CAR T cell therapy

Breakthrough Cancer Pain Managed Effectively With Fentanyl Buccal Tablets

Breakthrough Cancer Pain Managed Effectively With Fentanyl Buccal Tablets

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This prospective, noninterventional trial evaluated the response of 276 patients to FBT from 64 pain and oncology clinics

Combination of Western Care With Chinese Medicine Shows Potential in ITP

Combination of Western Care With Chinese Medicine Shows Potential in ITP

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The pathogenesis of idiopathic thrombocytopenic purpura (ITP) may be associated with Th17 helper T cells.

Distress Assessments Improve Psychosocial Support Referrals for HNC Patients

Distress Assessments Improve Psychosocial Support Referrals for HNC Patients

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A quality improvement project demonstrates that routine distress assessment using the NCCN DT/PL in patients with head and neck cancers improves referrals for psychosocial services.

Cause of Superior Vena Cava Syndrome in Cancer Determines Prognosis

Cause of Superior Vena Cava Syndrome in Cancer Determines Prognosis

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Prognosis for cancer patients with superior vena cava syndrome is highly associated with the underlying cause of the syndrome.

Affect of Daratumumab on Laboratory Blood Test Results

Affect of Daratumumab on Laboratory Blood Test Results

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Do monoclonal antibodies other than daratumumab cause false positives in the blood antibody screen and crossmatch obtained prior to a transfusion?

Anorexia-Cachexia in Non-Small Cell Lung Cancer Improved With Anamorelin

Anorexia-Cachexia in Non-Small Cell Lung Cancer Improved With Anamorelin

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Data from 5 phase 2/3 studies demonstrate improved weight and body mass in patients with NSCLC receiving anamorelin.

Early Recognition of Checkpoint Inhibitor-Related Pneumonitis Improves Outcomes

Early Recognition of Checkpoint Inhibitor-Related Pneumonitis Improves Outcomes

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As the use of checkpoint inhibitors increases in many types of cancer, oncology nurses need to learn to recognize the signs and symptoms of pneumonitis, a rare but life-threatening adverse effect of these agents.

Osteoporosis Medication Improves Bone Health in ADT-Treated Prostate Cancer

Osteoporosis Medication Improves Bone Health in ADT-Treated Prostate Cancer

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Osteoporosis medications were found to reduce bone mineral density loss and risk of fracture in men with nonmetastatic prostate cancer being treated with androgen-deprivation therapy.

Preventing Body-Trauma Triggers During Radiation Therapy for Cancer

Preventing Body-Trauma Triggers During Radiation Therapy for Cancer

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Some patients undergoing radiation therapy may experience traumatic symptoms if they had a prior experience that triggered their "fight, flight, or freeze" response. Somatic experiencing may help these patients manage their symptoms during their radiation treatments.

Palonosetron Prevents Delayed Nausea and Vomiting After CHOP in Non-Hodgkin Lymphoma

Palonosetron Prevents Delayed Nausea and Vomiting After CHOP in Non-Hodgkin Lymphoma

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Palonosetron effectively prevents and manages delayed CINV in patients with non-Hodgkin lymphoma.

ASCO Updates Guidelines for Antiemetic Therapy in Adult, Pediatric Patients Receiving Chemotherapy

ASCO Updates Guidelines for Antiemetic Therapy in Adult, Pediatric Patients Receiving Chemotherapy

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The American Society of Clinical Oncology (ASCO) convened a panel of experts to update its clinical guidelines for antiemetic therapy in patients receiving chemotherapy. A notable change is the addition of olanzapine in emetic regimens for adult patients.

Physical Activity Improves Cognitive Function for Breast Cancer Survivors

Physical Activity Improves Cognitive Function for Breast Cancer Survivors

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Moderate-to-vigorous physical activity was found to improve working memory and executive function in survivors of breast cancer.

Oropharyngeal Mucositis Pain Effectively Relieved With Indomethacin Oral Spray

Oropharyngeal Mucositis Pain Effectively Relieved With Indomethacin Oral Spray

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Indomethacin oral spray (IM-OS) is proven to be a safe and effective treatment for oropharyngeal mucositis pain in patients with cancer.

Acupuncture May Improve Fatigue in Patients with Lung Cancer

Acupuncture May Improve Fatigue in Patients with Lung Cancer

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Acupuncture was found to improve cancer-related fatigue in patients with lung cancer in as little as 2 weeks, according to results of a double-blind randomized clinical study.

Neuropathic Cancer Pain Linked to Reduced Quality of Life

Neuropathic Cancer Pain Linked to Reduced Quality of Life

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Results of a recent study showed that neuropathic cancer pain (NCP) in patients with cancer was not only associated with a worsened quality of life but is also not adequately managed.

Dexamethasone-Induced Hiccups in Chemotherapy May be Prevented by Rotating to Methylprednisolone

Dexamethasone-Induced Hiccups in Chemotherapy May be Prevented by Rotating to Methylprednisolone

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Rotating dexamethasone and methylprednisolone can help to alleviate dexamethasone-induced hiccups (DIH) without the loss of antiemetic effects in patients undergoing chemotherapy.

FDA Expands Clearance for Cooling Cap Use With Chemotherapy for Solid Tumors

FDA Expands Clearance for Cooling Cap Use With Chemotherapy for Solid Tumors

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The US FDA has granted expanded clearance for the DigniCap Cooling System to include use in patients undergoing chemotherapy for solid tumors in other areas of the body besides the breast.

Long-Term Use of TPO Receptor Agonist Safe in CLL-Associated Immune Thrombocytopenia

Long-Term Use of TPO Receptor Agonist Safe in CLL-Associated Immune Thrombocytopenia

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Case study demonstrates the effectiveness of long-term treatment with an oral nonpeptide receptor agonist in a 69-year-old male patient with CLL-associated ITP.

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Participants with high risk of depression reported lower mood disturbance, anxiety, depression following intervention.

Self-Reports on Adverse Effects From Younger Patients Are Reliable, Accurate

Self-Reports on Adverse Effects From Younger Patients Are Reliable, Accurate

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Children and adolescent patients with cancer are able to accurately report subjective adverse events (AEs) they experience during their cancer treatment, and they are willing to do so.

Program Focuses on How to 'Look Good Feel Better' During Cancer Treatment

Program Focuses on How to 'Look Good Feel Better' During Cancer Treatment

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American Cancer Society (ACS) program teaches patients with cancer how to repair their physical image when faced with the changes in their appearance brought on by cancer treatments.

Clinical Pathways: Paving the Way to Improve Patient-Centered and Cohesive Cancer Care

Clinical Pathways: Paving the Way to Improve Patient-Centered and Cohesive Cancer Care

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Cancer centers and hospital networks are finding both utility and value in clinical care pathways to help standardize diagnosis, treatment, and management of the most common disease presentations.

Lanreotide Eases Carcinoid Syndrome Symptoms in All Patients

Lanreotide Eases Carcinoid Syndrome Symptoms in All Patients

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Lanreotide decreased the proportion of days patients had flushing and diarrhea compared with placebo, even in patients previously responsive to rescue therapy with octreotide.

Brief Intervention Eases Distress in Patients With Advanced Cancer

Brief Intervention Eases Distress in Patients With Advanced Cancer

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Called CALM, the psychological intervention tries to help patients live with their disease rather than just prepare them for the end of life.

Combination Better At Easing Agitated Delirium in Advanced Cancer Patients

Combination Better At Easing Agitated Delirium in Advanced Cancer Patients

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Lorazepam plus haloperidol is more effective than haloperidol alone at reducing agitation, study finds.

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