Side-effect Management

Patients With Urologic Cancer Need Psycho-oncologic Support to Manage High Stress

Patients With Urologic Cancer Need Psycho-oncologic Support to Manage High Stress

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Patients with urologic cancer should be offered psycho-oncologic support to manage effects of emotional stressors.

Best Approach to Infection and Tumor Treatment: Contain or Eliminate?

Best Approach to Infection and Tumor Treatment: Contain or Eliminate?

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Using mathematical analysis, researchers identified factors to help determine if containment or the elimination of an infection or tumor, is most effective.

Treatment Outcomes Were Unchanged by Brentuximab Vedotin (BV)-induced Peripheral Neuropathy

Treatment Outcomes Were Unchanged by Brentuximab Vedotin (BV)-induced Peripheral Neuropathy

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Patients who were surveyed reported that the benefits of treatment with BV outweighed its risks.

Müllerian Inhibiting Substance Hormone Protects Ovaries From Chemotherapy Drugs in Mice

Müllerian Inhibiting Substance Hormone Protects Ovaries From Chemotherapy Drugs in Mice

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Müllerian inhibiting substance (MIS) may be employed to protect ovaries from the effects of chemotherapy, according to research done with mice.

Managing Adverse Effects From Oral Kinase Inhibitors in Patients With Hematologic Cancers

Managing Adverse Effects From Oral Kinase Inhibitors in Patients With Hematologic Cancers

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Ibrutinib, idelalisib, ponatinib, and ruxolitinib are each associated with a variety of potential adverse effects and oncology nurses must be aware of these to successfully monitor for them.

Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs

Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs

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Cancer survivors who reported chronic neuropathic pain 5 years after diagnosis were approximately 50% less likely to retain their jobs than those without chronic neuropathic pain.

Emerging Reproductive Technology Holds Great Potential and Risks for Patients, Research

Emerging Reproductive Technology Holds Great Potential and Risks for Patients, Research

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In vitro gametogenesis (IVG) offers hope for patients and survivors coping with disease-related and treatment-induced infertility, as well as providing a potentially unlimited supply of embryonic stem cells. However, legal and ethical issues need to be addressed before its widespread clinical use.

Cannabis Use Becoming More Common Among Older Patients

Cannabis Use Becoming More Common Among Older Patients

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Using data from previous analyses and several state medical cannabis programs, investigators assessed how social attitudes, health issues, and state laws affect the use of cannabis among persons older than 50 years.

Comprehensive Report Looks at Benefits and Harms of Medical Cannabis

Comprehensive Report Looks at Benefits and Harms of Medical Cannabis

Oral cannabinoids can ease chronic pain and chemotherapy-related nausea, but researchers cite risks, as well.

Hypnosis and Its Use in Cancer Treatment

Hypnosis and Its Use in Cancer Treatment

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A cursory look at hypnosis and where it may be used to offer an alternative and side-effect-free management of several aspects of care that can be beneficial to patients with cancer.

Menopause-specific QoL Changes Associated With Chemoprevention Nonadherence

Menopause-specific QoL Changes Associated With Chemoprevention Nonadherence

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A cohort of participants in the MAP.3 trial completed the MENQOL questionnaire, and the findings shed light on the influence of changes in menopause-specific quality of life on aromatase inhibitor adherence in women at high risk for breast cancer.

Diarrhea Common But Manageable With Pertuzumab-containing Regimens

Diarrhea Common But Manageable With Pertuzumab-containing Regimens

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Because treatment with pertuzumab could include adverse events similar to those observed with EGFR antagonists, such as diarrhea, researchers evaluated participants from 3 trials to determine the incidence and severity of diarrhea observed with pertuzumab.

Serum IL-12 May Predict for Chemotherapy-Related Fatigue in Early-Stage Breast Cancer

Serum IL-12 May Predict for Chemotherapy-Related Fatigue in Early-Stage Breast Cancer

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In this study, researchers sought to identify physical, neurocognitive, and serologic markers that may correlate with self-reported fatigue before and after (neo)adjuvant chemotherapy for patients with early-stage breast cancer.

Adding Aprepitant Not Superior to Ondansetron Monotherapy for UA-RINV

Adding Aprepitant Not Superior to Ondansetron Monotherapy for UA-RINV

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Many patients can still experience UA-RINV despite prophylactic therapy; therefore, researchers explored the effectiveness and safety of dual prophylactic therapy with an NK1 receptor antagonist and a 5-HT3 receptor antagonist.

Tissue Factor May Predict for Recurrent VTE in Patients Receiving Anticoagulants

Tissue Factor May Predict for Recurrent VTE in Patients Receiving Anticoagulants

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An evaluation of the association of tissue factor, clinical risk factors, and other biomarkers measured at the time of initial VTE with recurrent VTE helps determine their predictive value for patients at high risk.

Optimal Timing of Influenza Vaccination in Patients Receiving Chemotherapy

Optimal Timing of Influenza Vaccination in Patients Receiving Chemotherapy

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A comparison of administering the influenza vaccine concurrently with chemotherapy with that of administration within the cytopenic period during 3-week chemotherapy cycles determined which schedule was the optimal timing for vaccination administration in this group.

Patients With Breast Cancer Report More Cognitive Difficulties After Chemotherapy

Patients With Breast Cancer Report More Cognitive Difficulties After Chemotherapy

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Researchers sought to evaluate the incidence of cancer-related cognitive impairment in patients with breast cancer in a large prospective, longitudinal, nationwide study. These findings address limitations in previous research.

Scalp-cooling Device To Reduce Chemotherapy-related Alopecia

Scalp-cooling Device To Reduce Chemotherapy-related Alopecia

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A new system appears efficacious in preventing chemotherapy-related alopecia in women with breast cancer, according to a study presented at SABCS 2016.

Menopause-related Nausea/Vomiting and Headaches Effects Tamoxifen Adherence

Menopause-related Nausea/Vomiting and Headaches Effects Tamoxifen Adherence

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Women who experienced menopause-related side effects were significantly less likely to adhere to their assigned tamoxifen therapy.

Loperamide Regimen May Reduce Diarrhea in Neratinib-treated Patients

Loperamide Regimen May Reduce Diarrhea in Neratinib-treated Patients

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Investigators report on the efficacy of a structured prophylactic regimen of loperamide for 2 cycles to reduce incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer, at SABCS 2016.

Netupitant/Palonosetron Efficacious for Prevention of N/V in Patients Receiving MEC or HEC

Netupitant/Palonosetron Efficacious for Prevention of N/V in Patients Receiving MEC or HEC

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In a poster presentation at SABCS 2016, researchers reported on the efficacy and safety of netupitant/palonosetron (NEPA) for the prevention of CINV in patients receiving highly or moderately emetogenic chemotherapy.

Arsenic Pretreatment May Protect Normal Tissue During Chemo in Breast Cancer

Arsenic Pretreatment May Protect Normal Tissue During Chemo in Breast Cancer

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Researchers found that temporary pretreatment with LDA may protect normal breast tissue during chemotherapy for breast cancer in patients undergoing breast-conserving therapy, according to a study presented at SABCS 2016.

Perindopril, Bisoprolol Not Effective for Preventing Trastuzumab-mediated Left Ventricular Remodeling

Perindopril, Bisoprolol Not Effective for Preventing Trastuzumab-mediated Left Ventricular Remodeling

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Perindopril, an angiotensin-converting enzyme (ACE) inhibitor, and the beta blocker bisoprolol protected against trastuzumab-related declines.

Rasburicase More Effective Than Allopurinol for Tumor Lysis Syndrome

Rasburicase More Effective Than Allopurinol for Tumor Lysis Syndrome

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In patients with tumor lysis syndrome, rasburicase was significantly more effective in treating hyperuricemia and was associated with significantly shorter ICU stay.

Technique for Minimizing Chemotherapy-Induced Alopecia Gaining a Foothold in the States

Technique for Minimizing Chemotherapy-Induced Alopecia Gaining a Foothold in the States

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Inducing vasoconstriction in the scalp of patients with breast cancer undergoing chemotherapy effectively reduces the amount of drug that reaches the hair follicles and hair-cell metabolism, minimizing one of the most dreaded side effects of treatment.

Fecal Occult Blood Test, Colonoscopy Useful for Detecting Dasatinib-induced Colitis

Fecal Occult Blood Test, Colonoscopy Useful for Detecting Dasatinib-induced Colitis

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Researchers examined the frequency of TKI-induced hemorrhagic colitis among patients with CML treated with dasatinib and evaluated the efficacy of screening with a fecal occult blood test followed by colonoscopy in this patient population.

Resistance Training Improves Posttreatment Outcomes for Breast Cancer Survivors

Resistance Training Improves Posttreatment Outcomes for Breast Cancer Survivors

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Loss of bone density related to chemotherapy and adjuvant therapy for breast cancer can lead to debilitating hip and vertebral fractures. This discussion discusses the impact of resistance training for these patients.

Study Identifies Factors Associated With Platinum-induced Ototoxicity in Pediatric Cancer Survivors

Study Identifies Factors Associated With Platinum-induced Ototoxicity in Pediatric Cancer Survivors

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Large cohort study assesses the frequency of, and factors associated with, ototoxicity in childhood cancer survivors who received platinum agents without cranial irradiation.

Vaginal Ring/Cream May Be Feasible for Urogenital Atrophy

Vaginal Ring/Cream May Be Feasible for Urogenital Atrophy

The feasibility of an estradiol-releasing vaginal ring vs intravaginal testosterone cream for women with HR-positive stage I to III breast cancer using aromatase inhibitors who reported vaginal dryness, decreased libido, or dyspareunia is evaluated in a phase 2 study.

MASCC/ESMO Update Guidelines for CINV Prophylaxis

MASCC/ESMO Update Guidelines for CINV Prophylaxis

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The Multinational Association of Supportive Care in Cancer (MASCC) and the European Society for Medical Oncology (ESMO) have updated their recommendations for the prevention of nausea and vomiting following multiple-day chemotherapy.

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