Side Effects

Olanzapine Use to Prevent Chemotherapy-Induced Nausea and Vomiting

Olanzapine Use to Prevent Chemotherapy-Induced Nausea and Vomiting

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Why is the antipsychotic olanzapine (Zyprexa) being used to prevent nausea?

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

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Although many TKIs have well-documented cardiotoxic effects, results of a single-center prospective study that assessed effects of 1 year of therapy with imatinib or nilotinib in patients with CML demonstrated safety and efficacy of the 2 agents in this population.

Palonosetron Noninferior to Ondansetron for Pediatric Chemotherapy-induced Vomiting

Palonosetron Noninferior to Ondansetron for Pediatric Chemotherapy-induced Vomiting

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In a prospective study, researchers sought to determine the noninferiority of palonosetron to ondansetron in pediatric patients with cancer receiving moderate or high emetogenic chemotherapy.

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

Nabilone Improves Cancer-Associated Anorexia in Lung Cancer

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Researchers assessed the efficacy of nabilone for improving symptoms of anorexia in patients with NSCLC. In addition, patient appetite, quality of life, and nutritional status were also assessed.

Androgen-Deprivation Therapy for Prostate Cancer May Cause Nocturia, Sleep Disturbance

Androgen-Deprivation Therapy for Prostate Cancer May Cause Nocturia, Sleep Disturbance

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ADT recipients reported worse subjective sleep disturbance, researchers found.

CHEMO-SUPPORT: A Nursing Intervention to Relieve Chemotherapy Symptom Burden

CHEMO-SUPPORT: A Nursing Intervention to Relieve Chemotherapy Symptom Burden

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Results of a mixed-method study that used a combination of self-report tools evaluated the efficacy of CHEMO-SUPPORT, a patient support program designed to help patients manage their chemotherapy-related symptoms at home.

Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis

Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis

[Journal of Gastrointestinal Oncology] A review of diagnostic parameters and management modalities for checkpoint inhibitor-induced hepatic toxicity is presented.

Managing Chemo Brain in Pediatric Survivors of Childhood Cancer

Managing Chemo Brain in Pediatric Survivors of Childhood Cancer

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Reintegration to the general environment, particularly to school, can be challenging for survivors of childhood cancers. This review discusses how adverse effects such as chemo brain may present extra challenges for these patients and what can be done to ease patients' anxiety.

Intervention Improves Breast Cancer Survivors' Memory Contentment

Intervention Improves Breast Cancer Survivors' Memory Contentment

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Results of a prospective study demonstrated the effectiveness of a 1-hour psychoeducational intervention designed to help survivors of breast cancer manage their chemotherapy-related cognitive dysfunction and improve their memory contentment.

Advances in Prevention, Treatment of RT-Associated Radiodermatitis Hold Promise

Advances in Prevention, Treatment of RT-Associated Radiodermatitis Hold Promise

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This review of radiodermatitis, a common adverse effect of radiation therapy, discusses preventive and treatment options available that reduce and/or minimize symptoms of the condition.

Calcitriol May Improve Hormone-Therapy Induced Osteoporosis in Breast Cancer Survivors

Calcitriol May Improve Hormone-Therapy Induced Osteoporosis in Breast Cancer Survivors

In this study, researchers determined the efficacy of calcitriol, weight-bearing exercise, both, or daily multivitamins on bone formation and resorption in breast cancer survivors actively maintained on hormone therapy.

Zinc Sulfate Improves Chemotherapy-Induced Mucositis Outcomes in Leukemia

Zinc Sulfate Improves Chemotherapy-Induced Mucositis Outcomes in Leukemia

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Results of a triple-blind study demonstrate effectiveness of zinc sulfate in preventing chemotherapy-induced mucositis or reducing its incidence and severity in patients with leukemia receiving chemotherapy.

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

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In a secondary analysis of the BEATE and INVEST study, researchers followed a link between levothyroxine use, exercise, and fatigue in women with breast cancer undergoing chemotherapy.

Prevention, Management of Hand-Foot Syndrome With Cooling Therapy

Prevention, Management of Hand-Foot Syndrome With Cooling Therapy

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Researchers explored the effectiveness of wearing frozen gloves and socks before and after treatment with PLD to prevent or manage hand-foot syndrome in patients with ovarian cancer.

Resolving Vaginal Dryness in Women With a History of Breast Cancer

Resolving Vaginal Dryness in Women With a History of Breast Cancer

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What are some nonhormonal treatments that can improve vaginal dryness in women with a history of breast cancer?

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

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Researchers assessed outcomes for 587 patients with PV to determine the risk factors most likely to predict arterial or venous thrombosis in this patient population.

Incidence of Post-traumatic Stress Disorder High Among Patients With Cancer

Incidence of Post-traumatic Stress Disorder High Among Patients With Cancer

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Study evaluates the incidence of post-traumatic stress disorder in patients with cancer from diagnosis through survivorship.

Sarcopenia Severity Prognostic of Postchemotherapy Outcomes in the Elderly

Sarcopenia Severity Prognostic of Postchemotherapy Outcomes in the Elderly

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Using a series of functional tests, researchers determined the significance of sarcopenia severity after chemotherapy in older patients with cancer and its effect on their physical independence.

Hearing Loss, Tinnitus May Predict Worse Outcomes for Cancer Survivors

Hearing Loss, Tinnitus May Predict Worse Outcomes for Cancer Survivors

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A survey of 754 cancer survivors sought to determine the association between number of neurotoxicities such as CIN, hearing loss, and tinnitus and outcomes for these patients.

Exercise Reduces Severity of Chemotherapy-Induced Peripheral Neuropathy

Exercise Reduces Severity of Chemotherapy-Induced Peripheral Neuropathy

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For this study, researchers sought to determine the effect exercise would have on severity of symptoms for patients who develop CIPN after taxane, platinum, or vinca alkaloid based chemotherapy.

Clinical Aspects of Foot Health and Their Influence on Quality of Life Among Breast Cancer Survivors: A Case-control Study

Clinical Aspects of Foot Health and Their Influence on Quality of Life Among Breast Cancer Survivors: A Case-control Study

[Cancer Management and Research] Researchers determined the effect of breast cancer and its treatment on quality of life relative to foot health issues.

Aspirin Does Not Reduce Risk of Venous Thromboembolism in Multiple Myeloma

Aspirin Does Not Reduce Risk of Venous Thromboembolism in Multiple Myeloma

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A retrospective study, presented at ASH 2017, determined the effectiveness of aspirin in reducing risk of VTE in patients with multiple myeloma at high risk of developing VTE.

Relapsed Ph-Negative Acute Lymphoblastic Leukemia Incurs a High Economic Burden

Relapsed Ph-Negative Acute Lymphoblastic Leukemia Incurs a High Economic Burden

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Recent study findings investigated the economic burden of patients with relapsed Ph-negative ALL, and the adverse events of special interest that are most likely to have the greatest impact. These findings were presented at ASH 2017.

Arterial Thrombotic Events Associated With First-line Nilotinib for CML in Older Adults

Arterial Thrombotic Events Associated With First-line Nilotinib for CML in Older Adults

A retrospective analysis of patients with CML determined prevalence of arterial thrombotic events in those receiving nilotinib as first-line treatment and prevalence by patient age. Data were presented at ASH 2017.

Bioimpedance Spectroscopy Reduces Chronic BCRL in High-Risk Breast Cancer

Bioimpedance Spectroscopy Reduces Chronic BCRL in High-Risk Breast Cancer

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Results of a study evaluating the effectiveness of bioimpedance spectroscopy in reducing incidence of chronic breast cancer-related lymphedema (BCRL) in high-risk patients with breast cancer were presented at SABCS 2017.

Bundling Interventions Bridges Gender Gap in AYA Cancer Fertility Discussions

Bundling Interventions Bridges Gender Gap in AYA Cancer Fertility Discussions

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In this companion piece to our November column, we discuss the unique challenges to preserving the fertility of female patients with cancer and current options.

Efficacy of Curcumin in Reducing Radiation Dermatitis Severity Assessed

Efficacy of Curcumin in Reducing Radiation Dermatitis Severity Assessed

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A phase 2, randomized study investigated the effectiveness of oral curcumin, a component of turmeric, in reducing radiation dermatitis severity in patients undergoing radiation therapy for breast cancer.

Markers Identified for Cardiotoxicity Due to Chemotherapy for Breast Cancer

Markers Identified for Cardiotoxicity Due to Chemotherapy for Breast Cancer

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Biomarker analysis revealed markers for cardiotoxicity enabling early initiation of heart failure therapy in patients with breast cancer who were treated with chemotherapy.

Exercise May Mitigate Cardiotoxicity Associated With Doxorubicin Treatment

Exercise May Mitigate Cardiotoxicity Associated With Doxorubicin Treatment

Researchers injected Ewing sarcoma cells into mice to determine the effects of exercise on doxorubicin efficacy and treatment-related cardiotoxicity.

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