Side Effects

Resolving Vaginal Dryness in Women With a History of Breast Cancer

Resolving Vaginal Dryness in Women With a History of Breast Cancer

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What are some nonhormonal treatments that can improve vaginal dryness in women with a history of breast cancer?

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera

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Researchers assessed outcomes for 587 patients with PV to determine the risk factors most likely to predict arterial or venous thrombosis in this patient population.

Incidence of Post-traumatic Stress Disorder High Among Patients With Cancer

Incidence of Post-traumatic Stress Disorder High Among Patients With Cancer

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Study evaluates the incidence of post-traumatic stress disorder in patients with cancer from diagnosis through survivorship.

Sarcopenia Severity Prognostic of Postchemotherapy Outcomes in the Elderly

Sarcopenia Severity Prognostic of Postchemotherapy Outcomes in the Elderly

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Using a series of functional tests, researchers determined the significance of sarcopenia severity after chemotherapy in older patients with cancer and its effect on their physical independence.

Hearing Loss, Tinnitus May Predict Worse Outcomes for Cancer Survivors

Hearing Loss, Tinnitus May Predict Worse Outcomes for Cancer Survivors

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A survey of 754 cancer survivors sought to determine the association between number of neurotoxicities such as CIN, hearing loss, and tinnitus and outcomes for these patients.

Exercise Reduces Severity of Chemotherapy-Induced Peripheral Neuropathy

Exercise Reduces Severity of Chemotherapy-Induced Peripheral Neuropathy

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For this study, researchers sought to determine the effect exercise would have on severity of symptoms for patients who develop CIPN after taxane, platinum, or vinca alkaloid based chemotherapy.

Clinical Aspects of Foot Health and Their Influence on Quality of Life Among Breast Cancer Survivors: A Case-control Study

Clinical Aspects of Foot Health and Their Influence on Quality of Life Among Breast Cancer Survivors: A Case-control Study

[Cancer Management and Research] Researchers determined the effect of breast cancer and its treatment on quality of life relative to foot health issues.

Aspirin Does Not Reduce Risk of Venous Thromboembolism in Multiple Myeloma

Aspirin Does Not Reduce Risk of Venous Thromboembolism in Multiple Myeloma

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A retrospective study, presented at ASH 2017, determined the effectiveness of aspirin in reducing risk of VTE in patients with multiple myeloma at high risk of developing VTE.

Relapsed Ph-Negative Acute Lymphoblastic Leukemia Incurs a High Economic Burden

Relapsed Ph-Negative Acute Lymphoblastic Leukemia Incurs a High Economic Burden

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Recent study findings investigated the economic burden of patients with relapsed Ph-negative ALL, and the adverse events of special interest that are most likely to have the greatest impact. These findings were presented at ASH 2017.

Arterial Thrombotic Events Associated With First-line Nilotinib for CML in Older Adults

Arterial Thrombotic Events Associated With First-line Nilotinib for CML in Older Adults

A retrospective analysis of patients with CML determined prevalence of arterial thrombotic events in those receiving nilotinib as first-line treatment and prevalence by patient age. Data were presented at ASH 2017.

Bioimpedance Spectroscopy Reduces Chronic BCRL in High-Risk Breast Cancer

Bioimpedance Spectroscopy Reduces Chronic BCRL in High-Risk Breast Cancer

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Results of a study evaluating the effectiveness of bioimpedance spectroscopy in reducing incidence of chronic breast cancer-related lymphedema (BCRL) in high-risk patients with breast cancer were presented at SABCS 2017.

Bundling Interventions Bridges Gender Gap in AYA Cancer Fertility Discussions

Bundling Interventions Bridges Gender Gap in AYA Cancer Fertility Discussions

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In this companion piece to our November column, we discuss the unique challenges to preserving the fertility of female patients with cancer and current options.

Efficacy of Curcumin in Reducing Radiation Dermatitis Severity Assessed

Efficacy of Curcumin in Reducing Radiation Dermatitis Severity Assessed

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A phase 2, randomized study investigated the effectiveness of oral curcumin, a component of turmeric, in reducing radiation dermatitis severity in patients undergoing radiation therapy for breast cancer.

Markers Identified for Cardiotoxicity Due to Chemotherapy for Breast Cancer

Markers Identified for Cardiotoxicity Due to Chemotherapy for Breast Cancer

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Biomarker analysis revealed markers for cardiotoxicity enabling early initiation of heart failure therapy in patients with breast cancer who were treated with chemotherapy.

Exercise May Mitigate Cardiotoxicity Associated With Doxorubicin Treatment

Exercise May Mitigate Cardiotoxicity Associated With Doxorubicin Treatment

Researchers injected Ewing sarcoma cells into mice to determine the effects of exercise on doxorubicin efficacy and treatment-related cardiotoxicity.

Axillary Lymph Node Dissection Predictive for Lymphedema in Breast Cancer

Axillary Lymph Node Dissection Predictive for Lymphedema in Breast Cancer

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Researchers investigated the incidence of lymphedema on patients with breast cancer treated with TAC after axillary lymph node dissection (ALND), with or without radiotherapy, and its impact on quality of life for patients.

Fertility Preservation in Male Adolescents and Young Adults With Cancer

Fertility Preservation in Male Adolescents and Young Adults With Cancer

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Increasing survival rates for AYA patients with cancer have heightened the importance of discussing fertility preservation options. In this column, we review the options for male patients and the significance of including a discussion of them as part of treatment planning.

Social, Psychiatric Variables Reduce Cognitive Functioning, QoL in HNC

Social, Psychiatric Variables Reduce Cognitive Functioning, QoL in HNC

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Data on psychosocial and psychiatric variables of patients with HNC prior to treatment was analyzed to determine the extent of cognitive impairment and quality of life for patients with head and neck cancer, and its impact on patient outcomes.

Critical Thinking Key to Effective Management of Adverse Effects in Lymphoma

Critical Thinking Key to Effective Management of Adverse Effects in Lymphoma

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Nurses' critical thinking perspective is key to recognizing and managing adverse effects in patients with lymphoma, and staying ahead of the curve in a rapidly changing clinical setting.

Adolescents With Cancer May Derive Benefit From Skills-targeted Interventions

Adolescents With Cancer May Derive Benefit From Skills-targeted Interventions

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Investigators randomly assigned 100 adolescents and young adults with cancer ages 12 to 25 years old 1:1 to the PRISM intervention or to non-directive usual psychosocial care.

Hospitalizations in Advanced Cancer: What Makes Patients Stay or Come Back

Hospitalizations in Advanced Cancer: What Makes Patients Stay or Come Back

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Investigators conducted a study involving more than 1000 patients with advanced cancer to assess the factors that contribute to prolonged hospital stays and increased risk for readmissions.

A Case of Immunotherapy-Induced Myocarditis Concomitant to MG in Lung Cancer

A Case of Immunotherapy-Induced Myocarditis Concomitant to MG in Lung Cancer

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In this case, a female patient with advanced lung cancer experiences a rare episode of nivolumab-induced Herzmyasthenie, emphasizing the need to be aware of the potential for rapid myocarditis concomitant with MG in patients undergoing treatment with anti-PD-1 monoclonal antibodies.

Lanreotide Effectively Controls Diarrhea, Flushing in Neuroendocrine Tumors

Lanreotide Effectively Controls Diarrhea, Flushing in Neuroendocrine Tumors

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Results of the double-blinded and initial open-label phases of the ELECT Study demonstrate the effectiveness of lanreotide in controlling diarrhea and flushing in patients with NETs presenting with carcinoid syndrome.

Neurotoxicity After CAR T-cell Therapy May Be Associated With Endothelial Activation

Neurotoxicity After CAR T-cell Therapy May Be Associated With Endothelial Activation

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Despite its high response rate, researchers are finding that patients with endothelial activation prior to lymphodepletion chemotherapy are at greater risk of neurologic adverse events after undergoing CAR T-cell therapy for relapsed/refractory B-ALL, CLL, or NHL.

Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret

Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret

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A survey followed up with an assessment via validated tools determined that patients with prostate cancer who experienced regret after radical prostatectomy were more susceptible to depression-associated sleep disorders.

Complications and Management of Coagulation Disorders in Leukemia Patients

Complications and Management of Coagulation Disorders in Leukemia Patients

[Blood and Lymphatic Cancer: Targets and Therapy] Investigators conduct 4 case studies that illustrate a range of coagulation disorders that can develop in patients with leukemia to elucidate the rationale and process of specific treatment options.

Symptoms, Economic Burden Reduce QoL in Gastrointestinal Cancer Survivors

Symptoms, Economic Burden Reduce QoL in Gastrointestinal Cancer Survivors

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A cross-sectional survey revealed the impact of symptoms and economic burden on quality of life for survivors of gastrointestinal cancer.

Naldemedine Effective for Opioid-Induced Constipation in Cancer Pain

Naldemedine Effective for Opioid-Induced Constipation in Cancer Pain

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Opioids are an effective option for managing cancer pain; however, opioid-induced constipation (OIC) detracts from their effectiveness. In this study, investigators sought to determine if naldemedine use improved OIC without reducing pain relief.

Spontaneous Tumor Lysis Syndrome in Recently Diagnosed Small Cell Lung Cancer

Spontaneous Tumor Lysis Syndrome in Recently Diagnosed Small Cell Lung Cancer

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This case demonstrates that, although rare, spontaneous TLS can occur even in the absence of chemotherapy, and a high index of suspicion for the effect should be maintained when patients with malignancies demonstrate the classic symptom of laboratory abnormalities.

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