Side Effects

Preventing Tumor Lysis Syndrome in Patients Receiving Venetoclax

Preventing Tumor Lysis Syndrome in Patients Receiving Venetoclax

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What precautions should be taken to prevent tumor lysis syndrome (TLS) in patients receiving venetoclax (Venclexta)?

Pseudohyperkalemia: False Potassium Levels Occur in a Patient With Lymphoma

Pseudohyperkalemia: False Potassium Levels Occur in a Patient With Lymphoma

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The patient's history and current blood work results indicated a dangerously high potassium level. But a meticulously handled redraw proved it false.

Study Confirms Long-term Risk of VTE in Patients With Breast Cancer

Study Confirms Long-term Risk of VTE in Patients With Breast Cancer

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Patients with breast cancer have more than 2 times the risk for developing a venous thromboembolism 5 years after diagnosis compared with the general population.

Risk of Endometrial Abnormalities With Adjuvant Tamoxifen for Early Stage Breast Cancer Is Low

Risk of Endometrial Abnormalities With Adjuvant Tamoxifen for Early Stage Breast Cancer Is Low

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For women receiving tamoxifen in the adjuvant setting for early stage breast cancer or as a preventive for high risk of breast cancer, the risk of developing endometrial pathology in those with negative uterine examination findings prior to treatment is very low.

E-HF Radiation Therapy Side Effects Comparable to CF Radiation Therapy in Prostate Cancer

E-HF Radiation Therapy Side Effects Comparable to CF Radiation Therapy in Prostate Cancer

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Side effects experienced with extremely hypofractionated treatment for intermediate-risk prostate cancer were comparable to those of conventional radiation therapy at 2 years after treatment.

Drug Prevents Heart Damage in Pediatric Patients Receiving Chemotherapy

Drug Prevents Heart Damage in Pediatric Patients Receiving Chemotherapy

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Dexrazoxane has cardioprotective properties that can prevent long-term cardiotoxicity in pediatric patients receiving chemotherapy, according to a review of the medical literature on cardiotoxic effects of anthracycline treatment.

PMPS: A Common Late Effect of Surgery and Radiation for Breast Cancer

PMPS: A Common Late Effect of Surgery and Radiation for Breast Cancer

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Postmastectomy pain syndrome (PMPS) is a debilitating late effect of surgery and radiation therapy for breast cancer.

Study Evaluates Incidence of PD-1 Blockade-related Pneumonitis

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Pneumonitis related to the use of PD-1 inhibitor therapy is higher among patients with NSCLC and RCC, and during combination therapy.

Sexual Dissatisfaction Prevalent Among Cancer Survivors, Especially in Women

Sexual Dissatisfaction Prevalent Among Cancer Survivors, Especially in Women

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Older cancer survivors' self-reports of sexual activity and functioning are comparable to age-matched people without cancer; despite this, sexual dissatisfaction is more prevalent among cancer survivors than age-matched cancer-free persons.

Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors

Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors

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Although most adolescent survivors of childhood cancer have no reported psychological symptoms, those who do often have multiple symptoms and distinct symptom profiles.

A Systematic Review and Meta-analysis of the Risk of Diarrhea Associated With Vandetanib Treatment in Carcinoma Patients

A Systematic Review and Meta-analysis of the Risk of Diarrhea Associated With Vandetanib Treatment in Carcinoma Patients

[OncoTargets and Therapy] This research examines overall risks of all-grade and high-grade diarrhea during vandetanib treatment, to gain a better understanding of its prediction and management.

Chronic Pain Is More Likely for Women Who Undergo Armpit Lymph Node Surgery for Breast Cancer

Chronic Pain Is More Likely for Women Who Undergo Armpit Lymph Node Surgery for Breast Cancer

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Risk factors for chronic pain after breast cancer surgery include axillary lymph node dissection, younger age, and radiation therapy. Only axillary lymph node dissection is a high-yield target for a modifiable risk factor to prevent the persistent pain after breast cancer surgery.

Poor Sleep Quality Negatively Impacts Some Adverse Effects in Patients With Advanced Cancer

Poor Sleep Quality Negatively Impacts Some Adverse Effects in Patients With Advanced Cancer

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Patients participating in early-phase clinical trials should be assessed for sleep quality, as poor sleep quality is associated with greater fatigue, symptom burden, and mood disturbance.

Tango Dancing Improves Balance and Fall Risk in Cancer Patients With Peripheral Neuropathy

Tango Dancing Improves Balance and Fall Risk in Cancer Patients With Peripheral Neuropathy

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Balanced is improved and fall risk is reduced among cancer patients with peripheral neuropathy who participated in Argentine tango dancing as a form of therapy.

Cause of Pain of Photodynamic Therapy Identified

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Exaggerated sensitivity to harmless light, or photosensitization, is often triggered by photodynamic therapy used to treat precancerous skin lesions and skin cancers.

Moderate-to-Vigorous Exercise Improves Subjective Memory in Breast Cancer Survivors

Moderate-to-Vigorous Exercise Improves Subjective Memory in Breast Cancer Survivors

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Memory problems in breast cancer survivors appear associated with the high stress load these patients experience rather than their treatment, and moderate-to-vigorous physical activity may help subjective memory in these patients.

Case Reports Show an Association Between Immune Checkpoint Inhibitors and Risk for Rheumatologic Disorders

Case Reports Show an Association Between Immune Checkpoint Inhibitors and Risk for Rheumatologic Disorders

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A small number of patients with cancer treated with immune checkpoint inhibitors may have higher-than-usual risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a case report on 13 patients has shown.

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

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Quality of life for patients with oral cancer can be dismal due to cancer-related pain. An NIDCR grant is supporting the investigation of a nonviral gene delivery method for treating oral cancer pain safely and effectively.

Sleep Disorders in Cancer Radiation Therapy: Little Understood, Often Undetected — and Important

Sleep Disorders in Cancer Radiation Therapy: Little Understood, Often Undetected — and Important

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Sleep patterns and habits should be a part of oncology nurses' routine patient assessment, as sleep disorders can be a significant challenge for cancer patients undergoing radiation therapy.

Recently Identified Biomarkers Found to Warn of Chronic Graft-vs-Host Disease in Marrow Transplant Patients

Recently Identified Biomarkers Found to Warn of Chronic Graft-vs-Host Disease in Marrow Transplant Patients

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Researchers recently identified CXCL10, a protein that could act as a biomarker for chronic graft-versus-host disease (cGVHD), a long-term adverse effect that develops in some patients after undergoing blood and bone marrow transplant.

Premedication With Antiemetic Improves Length of Stay and Readmissions for a Liver Cancer Procedure

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Including an antiemetic in the preprocedure medications for patients with liver cancer undergoing drug eluting bead chemoembolization (DEB TACE) can shorten hospital stays and reduce the chance for readmission due to complications.

Timing Chemotherapy Administration to Circadian Rhythm Improves Drug Effectiveness

Timing Chemotherapy Administration to Circadian Rhythm Improves Drug Effectiveness

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Aligning chemotherapy administration to the time of day when the body is most awake benefits the effectiveness of the treatment, as shown in a mouse model.

Higher Concentrations of Methotrexate for Pediatric Leukemia Affect Long-Term Cognitive Processes

Higher Concentrations of Methotrexate for Pediatric Leukemia Affect Long-Term Cognitive Processes

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Pediatric patients with ALL treated with methotrexate can experience challenges with mental flexibility and organization compared with expectations from the general population.

Novel Device Captures Excess Chemotherapy, Avoiding Systemic Exposure to the Drugs

Novel Device Captures Excess Chemotherapy, Avoiding Systemic Exposure to the Drugs

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A new material was developed to soak up chemotherapy drugs after the tumor is treated and before they can circulate throughout the body, potentially limiting the side effects of chemotherapy.

Trastuzumab-related Cardiotoxicity Lower Among Taiwanese Patients

Trastuzumab-related Cardiotoxicity Lower Among Taiwanese Patients

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Trastuzumab-related cardiotoxicity was far lower in Taiwanese women with breast cancer compared with previously published results, according to recent study data.

Frailty Is a Concerning Factor Among Young Bone Marrow Transplant Survivors

Frailty Is a Concerning Factor Among Young Bone Marrow Transplant Survivors

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Incidence of frailty among young survivors of bone marrow transplant is similar to that of the elderly population, and increases the risk of death compared with nonfrail survivors.

'Breaking Bad' Symptoms: Constipation, Fatigue, Peripheral Neuropathy, Nausea and Vomiting

'Breaking Bad' Symptoms: Constipation, Fatigue, Peripheral Neuropathy, Nausea and Vomiting

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"Patients who feel better, live longer." And, to help patients feel better, clinicians need to provide optimal symptom management, said Eric Roeland, MD, GI Oncology & Palliative Care, UC San Diego Moores Cancer Center, San Diego, California, discussant for 4 poster presentations at the ASCO 2016 Annual Meeting.

Cisplatin-Associated Hearing Loss Is More Severe in Patients With Cockayne Syndrome

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Although cisplatin can kill cancer, the agent also causes permanent hearing loss. The drug kills sensory cells of the inner ear, and the effects on the inner ear are likely more severe in persons with the rare form of dwarfism known as Cockayne syndrome.

Cancer-related Neuropathy May Respond to Gene Therapy

Cancer-related Neuropathy May Respond to Gene Therapy

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Recent research using rats indicates that gene therapy might treat the neuropathic pain that affects 90% of patients with cancer.

Implementing a Distress Screening Process for Cancer Patients

Implementing a Distress Screening Process for Cancer Patients

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Highest points of distress experienced by patients with cancer at 1 institution are identified in this study to better implement distress screening.

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