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SECTRAL
CHF and arrhythmias
Hypertension
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Drug Name:

SECTRAL Rx

Generic Name and Formulations:
Acebutolol (as HCl) 200mg, 400mg; caps.

Company:
Dr. Reddy's Laboratories, Inc.

Therapeutic Use:

Indications for SECTRAL:

Ventricular arrhythmias.

Adult:

Initially 200mg twice a day. Usual range: 600mg–1.2g daily.

Children:

Not recommended.

Elderly:

Max 800mg/day.

Contraindications:

Severe bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

Bronchospastic disease. Ischemic heart disease or failure. Renal or hepatic dysfunction. Diabetes. Hyperthyroidism. Vascular insufficiency. Surgery. Avoid abrupt cessation. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

May potentiate hypotension with prazosin, reserpine, other catecholamine-depleting drugs. Antagonized by NSAIDs. May increase cardiac effects of verapamil, digitalis. Avoid α-adrenergic agonists. May block epinephrine.

Pharmacological Class:

Cardioselective beta-blocker.

Adverse Reactions:

Fatigue, dizziness, headache, GI upset, dyspnea, dysuria, insomnia, rash, myalgia, rhinitis, abnormal vision, hypotension, bradycardia, heart failure or block, bronchospasm, elevated ANA titers.

How Supplied:

Caps—100

Indications for SECTRAL:

Hypertension.

Adult:

Initially 400mg daily in 1–2 divided doses. Usual range: 200–800mg daily; max 1.2g/day in 2 divided doses.

Children:

Not recommended.

Elderly:

Max 800mg/day.

Contraindications:

Severe bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. Cardiogenic shock.

Warnings/Precautions:

Bronchospastic disease. Ischemic heart disease or failure. Renal or hepatic dysfunction. Diabetes. Hyperthyroidism. Vascular insufficiency. Surgery. Avoid abrupt cessation. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

May potentiate hypotension with prazosin, reserpine, other catecholamine-depleting drugs. Antagonized by NSAIDs. May increase cardiac effects of verapamil, digitalis. Avoid α-adrenergic agonists. May block epinephrine.

Pharmacological Class:

Cardioselective beta-blocker.

Adverse Reactions:

Fatigue, dizziness, headache, GI upset, dyspnea, dysuria, insomnia, rash, myalgia, rhinitis, abnormal vision, hypotension, bradycardia, heart failure or block, bronchospasm, elevated ANA titers.

How Supplied:

Caps—100

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