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SECONAL SODIUM
Anxiety/OCD
Sleep-wake disorders
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Drug Name:

SECONAL SODIUM CII

Generic Name and Formulations:
Secobarbital sodium 50mg, 100mg; caps.

Company:
Valeant Pharmaceuticals, Inc

Therapeutic Use:

Indications for SECONAL SODIUM:

For use as a preanesthetic sedative.

Adult:

200–300mg 1–2 hours before surgery. Elderly, debilitated, hepatic or renal impairment: reduce dose.

Children:

2–6mg/kg before surgery. Max 100mg.

Contraindications:

Manifest or latent porphyria. Marked hepatic impairment. Respiratory disease in which dyspnea or obstruction evident.

Warnings/Precautions:

Premonitory signs of hepatic coma: not recommended. Renal or hepatic impairment. Acute or chronic pain. Depression. Suicidal tendencies. Drug or alcohol abuse. Monitor hematopoietic, renal, hepatic systems with long-term therapy. Avoid abrupt cessation. Write ℞ for smallest practical amount. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat. D); may cause fetal damage. Nursing mothers.

Interactions:

Avoid concomitant griseofulvin. May antagonize oral anticoagulants (eg, warfarin), corticosteroids (may require dosage adjustments), doxycycline (monitor), oral contraceptives (consider alternative contraceptive method). May be potentiated by sodium valproate, valproic acid, MAOIs. Additive CNS depressant effects with alcohol, other CNS depressants. Concomitant phenytoin: monitor blood levels frequently.

Pharmacological Class:

Barbiturate.

Adverse Reactions:

Somnolence, agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, sleep-driving, hallucination, insomnia, anxiety, dizziness, abnormal thinking, hypoventilation, apnea, bradycardia, hypotension, syncope, GI upset, constipation, headache, hypersensitivity reactions, fever, liver damage.

How Supplied:

Caps—100

Indications for SECONAL SODIUM:

For short-term (2 weeks) treatment of insomnia.

Adult:

100mg at bedtime. Limit use to 2 weeks. Elderly, debilitated, hepatic or renal impairment: reduce dose.

Children:

Not recommended.

Contraindications:

Manifest or latent porphyria. Marked hepatic impairment. Respiratory disease in which dyspnea or obstruction evident.

Warnings/Precautions:

Premonitory signs of hepatic coma: not recommended. Renal or hepatic impairment. Acute or chronic pain. Depression. Suicidal tendencies. Drug or alcohol abuse. Monitor hematopoietic, renal, hepatic systems with long-term therapy. Avoid abrupt cessation. Write ℞ for smallest practical amount. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat. D); may cause fetal damage. Nursing mothers.

Interactions:

Avoid concomitant griseofulvin. May antagonize oral anticoagulants (eg, warfarin), corticosteroids (may require dosage adjustments), doxycycline (monitor), oral contraceptives (consider alternative contraceptive method). May be potentiated by sodium valproate, valproic acid, MAOIs. Additive CNS depressant effects with alcohol, other CNS depressants. Concomitant phenytoin: monitor blood levels frequently.

Pharmacological Class:

Barbiturate.

Adverse Reactions:

Somnolence, agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, sleep-driving, hallucination, insomnia, anxiety, dizziness, abnormal thinking, hypoventilation, apnea, bradycardia, hypotension, syncope, GI upset, constipation, headache, hypersensitivity reactions, fever, liver damage.

How Supplied:

Caps—100

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