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Sarcoma News & Features

Propranolol May Be Repurposed to Treat Angiosarcoma

Propranolol May Be Repurposed to Treat Angiosarcoma

A drug currently used for hypertension may be effective for patients with soft tissue sarcoma, based on the finding of researchers in Europe.

Combination of Gemcitabine and New CHK1 Inhibitor Is Effective in Soft Tissue Sarcomas

In a phase 1 clinical trial, the combination produces a significant and long-lasting response in patients with advanced disease including metastases to the peritoneum and lung.

Olaratumab in Combo With Doxorubicin Approved for Soft Tissue Sarcoma

The US FDA granted accelerated approval to olaratumab (Lartruvo) in combination with doxorubicin for the treatment of certain patients with soft tissue sarcoma.

Experimental Targeted Therapy Succeeds in Rare Pediatric Cancer

The experimental treatment LOXO-101 led to remarkable improvement for a 20-month-old girl whose rare pediatric cancer did not respond to surgery or chemotherapy.

New Therapy Holds Promise for Patients With Ewing Sarcoma

Two new compounds suppress tumor growth in cell culture and mouse xenograft models of Ewing sarcoma, a rare pediatric cancer. These 2 compounds are similar to mithramycin, also known as picamycin, a drug no longer manufactured due to its toxicity.

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