Combining a Wee1 protein inhibitor with the chemotherapy agent gemcitabine reduced sarcoma tumor volume more than did either drug alone.
In synovial sarcoma, metastasis development is linked to chromosome complexity.
Researchers have identified a group of liposarcoma tumors that can be imaged by positron emission tomography scans using a tracer substance known as FAC.
The American Society of Clinical Oncology has released a nearly 100-page report detailing the year's most significant developments in cancer.
Persons with metastatic colorectal cancer or gastrointestinal stromal tumors may garner some survival benefit from regorafenib after standard treatments have failed.
Discovery of a new drug with high potential to treat Ewing sarcoma and of the previously unknown mechanism behind the disease came hand-in-hand.
Pazopanib is a tyrosine kinase inhibitor indicated for renal cell carcinoma and advanced soft tissue sarcoma in patients who have received prior chemotherapy.
Thiabendazole, an antifungal drug in clinical use for 40 years, inhibits angiogenesis, slows tumor growth, and reduces vascular density of tumors.
Vincristine is a vinca alkaloid indicated for the treatment of certain cancers, and may also be used in some combination therapies.
Scientists have identified a protein that makes some children and teenagers afflicted with Ewing sarcoma more resistant to chemotherapy.
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