Risk Factors

Nipple-sparing Mastectomy Safe for Women With High Risk of Breast Cancer

Nipple-sparing Mastectomy Safe for Women With High Risk of Breast Cancer

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Prophylactic nipple-sparing mastectomy is as effective at preventing breast cancer as more invasive surgeries, according to a multi-institution study.

Higher Vitamin D Levels Lower Risk of Cancer in Women

Higher Vitamin D Levels Lower Risk of Cancer in Women

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Higher serum levels of 25-hydroxyvitamin D (25(OH)D) correlated with a reduced risk of cancer in women.

Risk of Bladder Cancer Higher for Patients Taking a Specific Diabetes Medication

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Pioglitazone use correlated with increased rates of bladder cancer across a large population. The risk of developing bladder cancer also increased with higher dose and longer use of the drug.

Mastectomy Increases Life Expectancy in Younger Women With Ovarian Cancer

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Risk-reducing mastectomy (RRM) can increase life expectancy and be cost effective in women up to age 60 years with ovarian cancer as carriers of a BRCA mutation.

Arterial Calcification Seen on Mammography Linked to Risk of Heart Disease

Arterial Calcification Seen on Mammography Linked to Risk of Heart Disease

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The amount of calcium in the arteries of the breast, readily visible on digital mammography, is linked to the level of calcium buildup in the coronary arteries.

How Insulin Levels Are Managed Affects Breast Density in Women With Diabetes

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Diabetes treatments, such as diet or pills (eg, metformin), decrease mammographic density, whereas insulin may increase mammographic density.

Newly Identified Gene Mutation Predominant in Chinese With a Family History of Breast Cancer

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Germline mutations to the RECQL gene were identified in 0.5% of patients with familial breast cancer in a Chinese population.

Vitamin D Deficiency Increases Risk of Tumor Growth and Metastasis in Breast Cancer

Vitamin D Deficiency Increases Risk of Tumor Growth and Metastasis in Breast Cancer

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Deficiency in vitamin D resulted in breast cancer tumors that grew faster and were more likely to metastasize, according to a recent study using mouse and cell culture models. The study also demonstrated a correlation between serum vitamin D levels and ID1.

Prognosis Poor for Women With Pregnancy-Associated Melanoma

Prognosis Poor for Women With Pregnancy-Associated Melanoma

Among women aged up to 49 years with a pregnancy-associated melanoma, recurrence rates were higher than seen in other groups.

Gingivitis Bacteria Associated With Esophageal Cancer

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Bacteria that cause gum disease, Porphyromonas gingivalis, frequently infect the esophageal tissues of patients with esophageal squamous cell carcinoma (ESCC), were associated with ESCC progression, and serve as a potential biomarker for ESCC.

Breast Cancer Risk Higher in Latinas Who Consume Processed Meats

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Eating processed meats such as bacon and sausage may increase the risk for breast cancer in Latinas, while the same association was not found in white women.

Agent Orange Linked to Bladder Cancer

Agent Orange Linked to Bladder Cancer

New evidence links exposure to the herbicide Agent Orange with bladder cancer and hypothyroidism among U.S. military personnel.

Regular Aspirin Use Could Reduce Colorectal, Gastrointestinal, and Overall Cancer Risks

Regular Aspirin Use Could Reduce Colorectal, Gastrointestinal, and Overall Cancer Risks

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Regular, low doses of aspirin for a minimum of 6 years correlated with a small, yet significant reduction in overall cancer risk, due primarily to reductions in risks for colorectal cancer and gastrointestinal cancer.

Study Findings Show Possible Association Between PreLabor Cesarean Delivery and Risk for ALL in Young Children

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The finding that prelabor cesarean delivery may have a correlation with acute lymphoblastic leukemia (ALL) may offer new targets for research into preventing cancer.

Should Vital Signs Be Routinely Obtained Prior to Intravenous Chemotherapy? Results From a 2-Center Study

Should Vital Signs Be Routinely Obtained Prior to Intravenous Chemotherapy? Results From a 2-Center Study

[Cancer Control] This research sought to explore whether routine checking of vital signs prior to administration of intravenous chemotherapy is associated with fewer complications, particularly hospitalizations and emergency department (ED) visits.

Nine Additional Inherited Gene Mutations Are Linked to Ovarian Cancer

Nine Additional Inherited Gene Mutations Are Linked to Ovarian Cancer

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Among 1915 patients with ovarian cancer, almost 1 in 5 had inherited mutations in genes associated with risk of ovarian cancer. Furthermore, a total of 11 genes are now suspected of causing hereditary ovarian cancer.

Fat Injection for Postmastectomy Breast Reconstruction Does Not Increase Risk of Recurrent Breast Cancer

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The use of lipofilling for postmastectomy breast reconstruction does not increase the risk of recurrent breast cancer. These findings are from an analysis of a plastic surgery database.

Earlier and More Frequent Tanning Bed Use by Women Associated With Melanoma Incidence and Age at Diagnosis

Earlier and More Frequent Tanning Bed Use by Women Associated With Melanoma Incidence and Age at Diagnosis

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Younger age at first use and more frequent use of indoor tanning beds are largely responsible for the steep increase in melanoma diagnoses in women younger than 40 years.

Prognosis Is Poor for Women With Pregnancy-Associated Melanoma

Prognosis Is Poor for Women With Pregnancy-Associated Melanoma

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A recent study showed that women younger than 50 years who are pregnant or were recently pregnant at diagnosis of melanoma have a higher risk of death from the skin cancer.

Fewer Mammography Screenings Are Safer in Women With Large Breasts or Implants

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The risk of radiation-induced breast cancer is higher for women with large breasts or breast implants because extra screening views often increase their radiation exposure.

Lethal Prostate Cancer Risk Lower With Regular Aspirin Use

Lethal Prostate Cancer Risk Lower With Regular Aspirin Use

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The risk of lethal prostate cancer, but not of overall, high-grade, or advanced cancers, was reduced with regular aspirin use.

Use of Electronic Cigarettes May Not Be Any Safer Than Smoking Tobacco Cigarettes

Use of Electronic Cigarettes May Not Be Any Safer Than Smoking Tobacco Cigarettes

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A California laboratory team tested two electronic cigarette products and found both products, and their nicotine-free versions, caused cell damage that could lead to cancer.

Postmenopausal Women With Periodontal Disease Have an Increased Risk of Developing Breast Cancer

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Postmenopausal women with periodontal disease are more likely to develop breast cancer than women who do not have the chronic inflammatory disease.

Family Members of Patients With CUP Are At Increased Risk for Several Types of Cancer

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Family members of patients with cancers of unknown primary (CUP) are at higher risk of developing CUP themselves, as well as cancers of the lung, pancreas, and colon and some cancers of the blood.

Combination Estrogen/Continuous Progestin Reduces Postmenopausal Risk of Endometrial Cancer

Combination Estrogen/Continuous Progestin Reduces Postmenopausal Risk of Endometrial Cancer

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Adding continuous progestin to estrogen lowers the risk of endometrial cancer in postmenopausal women, according to a new study.

Certain Characteristics Increase Leukemia Risk for Some Breast Cancer Survivors

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A new analysis indicates that certain characteristics may indicate a higher risk of developing leukemia after chemotherapy and/or radiation for breast cancer survivors.

Incidence of Undetected Cancer in Patients Undergoing Gynecologic Surgery for a Benign Condition Higher Than Estimated

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Researchers in Massachusetts sought to determine how frequently cancer is diagnosed in women after undergoing gynecologic surgery for a problem believed to be benign.

Consistency of Lung Nodules Is Predictive of Lung Cancer Risk in Men and Women

Consistency of Lung Nodules Is Predictive of Lung Cancer Risk in Men and Women

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Women with a certain type of lung nodule visible on lung cancer screening CT scans face a higher risk of lung cancer than men with similar nodules, according to a study presented at RSNA 2015.

New Model for Breast Cancer Risk in Hispanic Women Is the First to be Based Exclusively on Data From Hispanic Women

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The first breast cancer risk-prediction model based entirely on data from Hispanic women, including whether a woman was born in or outside the United States, provides a more accurate assessment of Hispanic women's risk of developing breast cancer.

Breast Cancer Risk From Common Commercial-product Ingredient Greater Than Previously Determined

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Parabens, estrogen-mimicking chemicals commonly found in an array of personal care products, may be more dangerous at lower doses than previously thought.

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