Risk Factors

Major breakthrough in understanding acute lymphoblastic leukemia

Major breakthrough in understanding acute lymphoblastic leukemia

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By analyzing the DNA sequence of patients at different stages of leukemia, researchers have discovered mutations in genes that lead to childhood leukemia of the acute lymphoblastic type, the most common childhood cancer.

Postmenopausal breast cancer risk drops off after starting regular physical activity

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Postmenopausal women who in the past 4 years had undertaken regular physical activity equivalent to at least 4 hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less

Mutations in the PALB2 gene increases risk of breast cancer by age 70 years

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The PALB2 gene is potentially one of the most important genes associated with breast cancer after the BRCA1/2 genes.

Chemoprotective effects of coffee

Chemoprotective effects of coffee

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Diet and nutrition are significant factors in preventing hepatic diseases progressing to hepatocellular carcinoma, and coffee is high on the list of good foods.

New mutations may increase breast cancer risk

New mutations may increase breast cancer risk

Mutations in PALB2 and germline mutations in the multiple endocrine neoplasia type 1 (MEN1) tumor-suppressor gene causing MEN1 correlate with increased breast cancer risk, according to two studies.

Secondhand Smoke and Cancer (Fact Sheet)

Secondhand Smoke and Cancer (Fact Sheet)

This fact sheet examines the relationship between secondhand smoke and cancer risk.

Recent use of some birth control pills may increase breast cancer risk

Recent use of some birth control pills may increase breast cancer risk

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Women who recently used birth control pills containing high-dose estrogen and a few other formulations had an increased risk for breast cancer, whereas women using some other formulations did not, according to recent data.

Specific genetic defect may increase melanoma susceptibility

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A new study shows how a genetic defect in a specific hormonal pathway may make people more susceptible to developing melanoma.

Novel approach reduces risk of cervical cancer

Novel approach reduces risk of cervical cancer

Researchers describe a novel approach to preventing cervical cancer. The study findings showed a reduction in cervical cancer risk after removal of a discrete population of cervical cells called squamocolumnar junction cells.

Here's What We Know About Cell Phone Use And the Risks For Cancer

Here's What We Know About Cell Phone Use And the Risks For Cancer

Cell phone emit radiation that can be absorbed by human tissue; however, that does not mean that cell phones can cause cancer. An important factor is that cell phone emit non-ionizing electromagnetic radiation—the kind of radiation emitted by microwave—not ionizing radiation—the kind that comes from x-rays.

Poor lifestyle choices blamed for large rise In liver and skin cancers

Poor lifestyle choices blamed for large rise In liver and skin cancers

Lifestyle factors such as overeating, smoking, drinking too much and not enough exercises may be to blame for a sharp rise in liver and skin cancer cases.

Four genes confirmed as increasing familial breast cancer risk

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Four new genes have been added to the growing list of those known to cause increased breast cancer risk when mutated.

Researchers at NYU and UCSF Develop a Framework for Monitoring Oral Cancer

Researchers at NYU and UCSF Develop a Framework for Monitoring Oral Cancer

Researchers at New York University College of Dentistry and at University of California San Francisco are investigating a potential association between oral cancers and chronic microbial diseases of the oral cavity.

Variation in BRCA2 gene linked to lung cancer, doubles a smoker's risk

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New research confirms a vulnerability to lung cancer can be inherited and implicates the BRCA2 gene as harboring one of the involved genetic mutations.

Prophylactic double mastectomy following breast cancer diagnosis often not needed

Prophylactic double mastectomy following breast cancer diagnosis often not needed

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Approximately 70% of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research has found.

ASCO: Obesity and ER+ breast cancer mortality link limited to pre-menopause

ASCO: Obesity and ER+ breast cancer mortality link limited to pre-menopause

In estrogen receptor (ER)+ breast cancer, obesity is positively associated with breast cancer mortality only among pre-/peri-menopausal women, according to new research.

Radiation therapy for cervical cancer increases risk for colorectal cancer

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Young women treated with radiation for cervical cancer should begin colorectal cancer screening earlier than traditionally recommended, according to new research.

Insights into why cancer incidence increases with age

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Age-associated changes in a biochemical process that helps control genes may be responsible for some of the increased risk of cancer seen in older people.

Obesity in men could dictate future colon screenings

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Elevated levels of the fat hormone leptin, higher BMI, and a larger waistline are associated with a greater likelihood of having colorectal polyps in men.

AACR: Higher melatonin levels tied to lower prostate cancer risk

AACR: Higher melatonin levels tied to lower prostate cancer risk

After adjusting for potential confounders, men with high levels of 6-sulfatoxymelatonin demonstrated a significantly lower prostate cancer risk.

Celebrity health stories tend to raise awareness but not knowledge of disease risk

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a new study reveals that widespread awareness of Angelina Jolie's mastectomy story did not translate into increased understanding of breast cancer risk.

Allergies increase risk of blood cancers in women

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A team of scientists looking into the interplay of the immune system and cancer have found a link between a having a history of airborne allergies with risk of blood cancers in women.

Central adiposity linked to esophageal cancer risk

Central adiposity linked to esophageal cancer risk

An association between central adiposity and increased risk of esophageal inflammation, metaplasia, and adenocarcinoma found.

Artificial Sweeteners and Cancer (Fact Sheet)

This fact sheet explores the evidence of links between artificial sweeteners and cancer risk.

Family history of adenomas ups CRC risk

Family history of adenomas ups CRC risk

Screening according to current guidelines could miss 10 percent of CRCs diagnosed in relatives.

AACR: Sedentary time linked to male CR adenoma recurrence

AACR: Sedentary time linked to male CR adenoma recurrence

Risk of colorectal adenoma recurrence up for men with low recreation activity, high sedentary time.

Esophageal and gastric cancers linked to teen weight

Esophageal and gastric cancers linked to teen weight

Adolescents' weight and socioeconomic status (SES) may affect their subsequent risk of developing esophageal and gastric cancer, according to a study.

Mexican women develop more aggressive forms of breast cancer despite protective factors

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Women of Mexican descent who had more children and breastfed were more likely to develop an aggressive breast cancer, according to results from the Ella Binational Breast Cancer Study.

One hour of walking per day may reduce breast cancer risk

One hour of walking per day may reduce breast cancer risk

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Researchers have uncovered a decreased risk of breast cancer among women who walk 7 or more hours per week compared with women who walk for 3 hours or less per week.

Secondary cancers: When treatment ­increases the risk of disease

Secondary cancers: When treatment ­increases the risk of disease

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Which cancer treatments can cause other cancers later in life?

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