Risk Assessment

JAK2 Mutation, Leukocytosis Are Predictive Factors of Thrombosis in Essential Thrombocythemia

JAK2 Mutation, Leukocytosis Are Predictive Factors of Thrombosis in Essential Thrombocythemia

By

Presence of JAK2 mutation and leukocytosis are strong predictors for thromboembolic events in patients with essential thrombocythemia (ET).

New Predisposition Genes for Familial Polycythemia Vera Are Identified

New Predisposition Genes for Familial Polycythemia Vera Are Identified

By

Predisposition genes for familial polycythemia vera were identified via exome sequencing in a Finnish family with 4 patients.

Distress Management Tool Gets an Update, Patient Version

Distress Management Tool Gets an Update, Patient Version

By

A review of the updated NCCN Guidelines is presented with a look at the newly published Guideline for Patients.

Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing

Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing

By

Limited use of genetic counselors and high rate of double mastectomy in women at average risk with early-stage breast cancer illustrate that understanding of genetic testing results is limited.

Recommendations Against Contralateral Prophylactic Mastectomy Not Tied to Patient Satisfaction

Recommendations Against Contralateral Prophylactic Mastectomy Not Tied to Patient Satisfaction

By

Study finds patients are not more likely to report dissatisfaction, seek a second opinion, or change doctors due to physician recommendations against CPM.

Trends in BRCA Mutation Testing Shifting Toward Unaffected Women

Trends in BRCA Mutation Testing Shifting Toward Unaffected Women

By

Genetic testing for BRCA gene mutation is increasingly undertaken by women unaffected by breast and/or ovarian cancers.

Risk of Second Cancers Increased in Hodgkin Lymphoma Survivors

Risk of Second Cancers Increased in Hodgkin Lymphoma Survivors

By

Hodgkin lymphoma survivors are at higher risk of second cancers, and that risk is even higher in those with a first-degree relative with cancer.

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

By

Predictive risk model shows that lifestyle choices have a greater influence on risk for colorectal cancer than does genetic factors.

Comorbidities May Predict Non-Home Discharge After Hysterectomy

Comorbidities May Predict Non-Home Discharge After Hysterectomy

By

Presence of 1 risk factor or 2 or more risk factors is associated with non-home discharge after hysterectomy for gynecologic malignancy.

Annual Screening of High-Risk Smokers Only More Cost-effective Than Current Methods

Annual Screening of High-Risk Smokers Only More Cost-effective Than Current Methods

By

Annual lung cancer screening of only high-risk smokers more cost-effective than current methods.

Inflammatory Cytokine Levels Increase Breast Tissue Density, Cancer Risk

Inflammatory Cytokine Levels Increase Breast Tissue Density, Cancer Risk

By

Discovered link between inflammation and overexpression of CCL2 hints at potential of anti-inflammatory medications as a breast cancer preventive in women with dense-tissue breasts.

Recurrence Score Appears To Be Driving Personalized Treatment for Breast Cancer

Recurrence Score Appears To Be Driving Personalized Treatment for Breast Cancer

By

The recurrence score assay stratifies early stage, estrogen receptor-positive breast cancer by recurrence risk. This study assessed how clinicians use the recurrence score to recommend adjuvant systemic therapy or patients' experiences with testing decision-making.

Socioeconomic Status Inversely Related to Risk for Ovarian Cancer in African American Women

By

Risk of ovarian cancer is higher in African American women with lower socioeconomic status, the opposite of trends seen in breast cancer.

Prophylactic Gynecologic Resections Increase Risk for Aggressive Uterine Cancer in BRCA Gene Mutation Carriers

By

Women who carry the BRCA1 mutation are at increased risk for serous/serous-like endometrial carcinoma after risk-reducing salpingo-oophorectomy. Yet uncertainty exists over the need to perform a full hysterectomy in these women.

Sleep Disorders in Cancer Radiation Therapy: Little Understood, Often Undetected — and Important

Sleep Disorders in Cancer Radiation Therapy: Little Understood, Often Undetected — and Important

By

Sleep patterns and habits should be a part of oncology nurses' routine patient assessment, as sleep disorders can be a significant challenge for cancer patients undergoing radiation therapy.

Baseline PSA Levels in Midlife Could Predict Risk of Lethal Prostate Cancer

Baseline PSA Levels in Midlife Could Predict Risk of Lethal Prostate Cancer

By

Screening PSA levels at midlife could identify men who are at greater risk of developing prostate cancer later in life and who should be monitored more closely.

Biochemical Marker Is a Better Predictor of Adverse Effects in Patients with Non-small Cell Lung Cancer

By

Albumin concentration with an established cutoff point is proven a better predictor of both chemotherapy toxicity and survival in patients with advanced lung cancer.

Prognostic Index Will Improve Clinical Practice Management of Patients With CLL and in Clinical Trials

Prognostic Index Will Improve Clinical Practice Management of Patients With CLL and in Clinical Trials

By

An international consortium devised an international prognostic index for chronic lymphocytic leukemia (CLL-IPI) that combines genetic, biochemical, and clinical parameters into a prognostic model to enable more targeted management of patients with CLL.

Rates of Colorectal Cancer Are Increasing in Younger Patients, Despite an Overall Decline

By

Reasons for the continuing increase in cases of young-onset colorectal cancer, despite a decline in the overall rate of the disease in recent years, are unclear.

Study Finds Racial Disparities in Breast and Ovarian Cancer Risk Management

Study Finds Racial Disparities in Breast and Ovarian Cancer Risk Management

By

Disparities in cancer risk management among BRCA carriers across a diverse sample of young black, Hispanic, and non-Hispanic white breast cancer survivors underscores that "the benefit from genetic testing comes from acting on the test results," not just the testing itself, a study presented at the ASCO 2016 Annual Meeting concluded.

Participants Understand Implications of Multiplex Gene Testing for Inherited Cancer Risk

Participants Understand Implications of Multiplex Gene Testing for Inherited Cancer Risk

By

Multiplex gene testing of diverse patients has found that patients who test positive advise relatives to test, "suggesting that participants understood the implications of test results," according to results of a planned interim analysis of a prospective trial presented at the ASCO 2016 Annual Meeting.

New Research Questions Recommendations Regarding PSA Tests for Prostate Cancer Screening

New Research Questions Recommendations Regarding PSA Tests for Prostate Cancer Screening

By

New research results favor testing for prostate specific antigen (PSA) levels for detection of prostate cancer. PSA tests can reduce the number of fatal cases of prostate cancer by detecting disease early.

Moderate Link for Automated and Clinical Breast Density Measures

Moderate Link for Automated and Clinical Breast Density Measures

Both automated and clinical assessments of breast density are associated with breast cancer risk.

Recent Cancer Diagnoses May Coincide With Mental Health Comorbidities

Recent Cancer Diagnoses May Coincide With Mental Health Comorbidities

By

Having a recent cancer diagnosis is associated with an increased risk for some mental health disorders and increased use of psychiatric medications.

More Than HPV Vaccine Uptake Is Needed to Reduce the Burden of HPV-associated Cancers

More Than HPV Vaccine Uptake Is Needed to Reduce the Burden of HPV-associated Cancers

By

Although HPV vaccination is expected to decrease the cancer burden from HPV across all racial and ethnic groups, some disparities are expected to persist and widen if their causes are not addressed, including lack of access to screening, timely diagnoses, and treatment.

German Study Confirms Accuracy of Multigene Test Predictions of Safe Omission of Chemotherapy for Breast Cancer

German Study Confirms Accuracy of Multigene Test Predictions of Safe Omission of Chemotherapy for Breast Cancer

By

A multigene test can identify patients with early stage breast cancer who do not need chemotherapy and who will be alive 5 years after diagnosis.

Risk Stratification and Treatment Options Differ for Male and Female Patients With Breast Cancer

By

Optimal risk stratification differs between male and female breast cancers. Outcomes for male patients with breast cancer were not significantly correlated with histologic grade, unlike for female patients.

High-risk HPV Infection Increases Risk for Anal Cancer

By

Anal cancer is associated with human papillomavirus (HPV) infection, and some women are at increased likelihood of have both diseases.

Familial Risk and Heritability of Cancer Is Higher Among Twins

By

Twins carry a significant excess familial risk for cancer overall and for specific types of cancer, including prostate, melanoma, breast, ovary, and uterus, according to a long-term follow-up study of twins in Nordic countries.

Risk for Colorectal Cancer Varies Among Latino Subgroups

By

Researchers found that colorectal cancer risk in Californian Latinos vary widely based on their country of origin.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs