The effectiveness of chemotherapy was enhanced by targeting survivin, a protein that inhibits apoptosis or cell death, according to preclinical research in cells and mouse models of retinoblastoma.
Ethnic, racial, and socioeconomic disparities appear to exist among children with retinoblastoma, a once uniformly fatal but now treatable eye cancer. Those disparities are associated with greater risks for advanced disease and undergoing removal of the eye.
Most retinoblastoma survivors do not have poorer psychosocial functioning compared with people without cancer.
Adult survivors of retinoblastoma, a type of eye cancer that usually develops in early childhood, are typically free from long-lasting effects, a new study shows.
Adults who survived childhood retinoblastoma have limited cognitive and social issues later in life.
A new technique to treat retinoblastoma may help prevent eye loss, blindness, or death in children with advanced forms of the disease.
Shortening the time from first appearance of symptoms to diagnosis has no bearing on survival or stage of disease in unilateral retinoblastoma, the most common form of childhood eye cancer, according to a new study.
Can parents use digital cameras and smart phones to potentially screen their children for the most common form of pediatric eye cancer? Researchers believe so.
A new type of retinoblastoma, which is a rapidly developing eye cancer that affects very young babies, has been discovered. This finding can immediately change clinical practice and optimize care for these children.
A prospective clinical trial conducted in France found that children with low-risk retinoblastoma do not need adjuvant chemotherapy to prevent disease recurrence or metastasis.
Using a classification strategy, all patients were event-free at a median 71 months of follow-up.
Younger patients receiving the drug for retinoblastoma have higher rates of ototoxicity.
Genetic evaluations by a multidisciplinary health team improved risk prediction for children with retinoblastoma and their relatives, and prevented overuse of clinical screening tests.
Intra-arterial chemotherapy (IAC) for treatment of retinoblastoma demonstrated a variable response rate but also evidence of ocular complications in a recent study.
Doctors may be able to save the eyes of children with retinoblastoma by using a plaque method, according to an ophthalmologist at Washington University School of Medicine in St. Louis.
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