Retinoblastoma

Targeted Therapy Enhances Chemotherapy, Improves Outcomes in Retinoblastoma

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The effectiveness of chemotherapy was enhanced by targeting survivin, a protein that inhibits apoptosis or cell death, according to preclinical research in cells and mouse models of retinoblastoma.

Ethnic, Racial, and Socioeconomic Disparities in Retinoblastoma in Children

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Ethnic, racial, and socioeconomic disparities appear to exist among children with retinoblastoma, a once uniformly fatal but now treatable eye cancer. Those disparities are associated with greater risks for advanced disease and undergoing removal of the eye.

Most retinoblastoma survivors have normal psychosocial functioning

Most retinoblastoma survivors have normal psychosocial functioning

Most retinoblastoma survivors do not have poorer psychosocial functioning compared with people without cancer.

Adult survivors of childhood eye cancer experience few cognitive or social setbacks

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Adult survivors of retinoblastoma, a type of eye cancer that usually develops in early childhood, are typically free from long-lasting effects, a new study shows.

Survivors of pediatric retinoblastoma have few cognitive and social problems during adulthood

Survivors of pediatric retinoblastoma have few cognitive and social problems during adulthood

Adults who survived childhood retinoblastoma have limited cognitive and social issues later in life.

New treatment for retinoblastoma expected to save more eyes from cancer

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A new technique to treat retinoblastoma may help prevent eye loss, blindness, or death in children with advanced forms of the disease.

Early detection of childhood eye cancer does not improve survival or prevent eye loss

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Shortening the time from first appearance of symptoms to diagnosis has no bearing on survival or stage of disease in unilateral retinoblastoma, the most common form of childhood eye cancer, according to a new study.

Smart phone photos for easier detection of pediatric eye cancer

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Can parents use digital cameras and smart phones to potentially screen their children for the most common form of pediatric eye cancer? Researchers believe so.

New type of retinoblastoma discovered in babies

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A new type of retinoblastoma, which is a rapidly developing eye cancer that affects very young babies, has been discovered. This finding can immediately change clinical practice and optimize care for these children.

Many children with retinoblastoma can safely forego adjuvant chemotherapy

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A prospective clinical trial conducted in France found that children with low-risk retinoblastoma do not need adjuvant chemotherapy to prevent disease recurrence or metastasis.

Risk-based chemotherapy effective for retinoblastoma

Risk-based chemotherapy effective for retinoblastoma

Using a classification strategy, all patients were event-free at a median 71 months of follow-up.

Ototoxicity Rates in Children Receiving Carboplatin Studied

Ototoxicity Rates in Children Receiving Carboplatin Studied

Younger patients receiving the drug for retinoblastoma have higher rates of ototoxicity.

Make genetic testing part of retinoblastoma care

Genetic evaluations by a multidisciplinary health team improved risk prediction for children with retinoblastoma and their relatives, and prevented overuse of clinical screening tests.

New treatment for retinal tumor should be used with caution

Intra-arterial chemotherapy (IAC) for treatment of retinoblastoma demonstrated a variable response rate but also evidence of ocular complications in a recent study.

New method designed to save vision of children with retinoblastoma

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Doctors may be able to save the eyes of children with retinoblastoma by using a plaque method, according to an ophthalmologist at Washington University School of Medicine in St. Louis.

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