Research

Recombinant human endostatin in combination with CHOP regimen for peripheral T cell lymphoma

Recombinant human endostatin in combination with CHOP regimen for peripheral T cell lymphoma

[OncoTargets and Therapy] This research examines the efficacy and safety of recombinant human endostatin in combination with CHOP regimen (ECHOP) for patients with peripheral T cell lymphoma.

Omega-3 Polyunsaturated Fatty Acids in the Prevention of Postoperative Complications in Colorectal Cancer: A Meta-analysis

Omega-3 Polyunsaturated Fatty Acids in the Prevention of Postoperative Complications in Colorectal Cancer: A Meta-analysis

[OncoTargets and Therapy] This research evaluates the clinical efficacy of omega-3 PUFAs in the prevention of postoperative complications in colorectal cancer patients.

What You Do Not Know Could Hurt You: What Women Wish Their Doctors Had Told Them About Chemotherapy Side Effects on Memory and Response to Alcohol

What You Do Not Know Could Hurt You: What Women Wish Their Doctors Had Told Them About Chemotherapy Side Effects on Memory and Response to Alcohol

[Breast Cancer: Basic and Clinical Research] This research examines the incidence of alcohol and memory-related side effects of chemotherapy in female cancer patients.

Comparison of Three Information Sources for Smoking Information in Electronic Health Records

Comparison of Three Information Sources for Smoking Information in Electronic Health Records

[Cancer Informatics] This research examinbed independent and joint performance of retrieving smoking status through different sources and compared the performance of retrieving smoking strength information from narrative text and PPI.

The evolution of the diminishing role of extrapleural pneumonectomy in the surgical management of malignant pleural mesothelioma

The evolution of the diminishing role of extrapleural pneumonectomy in the surgical management of malignant pleural mesothelioma

[OncoTargets and Therapy] The surgical approach that offers the best outcomes for malignant pleural mesothelioma management is still debated. This research examines the efficacy of surgical treatment.

Comparing Popular Commercial Cancer Gene Tests Yield Different Results

Comparing Popular Commercial Cancer Gene Tests Yield Different Results

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A head-to-head comparison of two commercial gene sequencing tests yielded differing results.

Management of Hypoglycemia in Nondiabetic Palliative Care Patients: A Prognosis-Based Approach

Management of Hypoglycemia in Nondiabetic Palliative Care Patients: A Prognosis-Based Approach

[Palliative Care: Research and Treatment] This research discusses the epidemiology, evidence-based recommendations, etiology, and mechanisms of hypoglycemia, as well as its management in hospice care or inpatient palliative care wards.

Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: The Evidence to Date

Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: The Evidence to Date

[Journal of Hepatocellular Carcinoma] This research examines tivantinib and its therapeutic profile in the management of hepatocellular carcinoma.

Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis

Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis

[OncoTargets and Therapy] This research examines the prognostic value of pretreatment serum albumin in RCC patients.

Role of Chemotherapy and Mechanisms of Resistance to Chemotherapy in Metastatic Castration-Resistant Prostate Cancer

Role of Chemotherapy and Mechanisms of Resistance to Chemotherapy in Metastatic Castration-Resistant Prostate Cancer

[Clinical Medicine Insights: Oncology] This research examines the various mechanisms of resistance to chemotherapy in metastatic CRPC and the potential role of emerging regimens and agents in varying clinical phases of development.

Hepatocellular Carcinoma: A Review

Hepatocellular Carcinoma: A Review

[Journal of Hepatocellular Carcinoma] This research examines the screening modalities, diagnosis, staging, and treatment of hepatocellular carcinoma (HCC), the most common primary liver malignancy.

Economic Burden Related to Chemotherapy-related Adverse Events in Patients with Metastatic Breast Cancer in an Integrated Health Care System

Economic Burden Related to Chemotherapy-related Adverse Events in Patients with Metastatic Breast Cancer in an Integrated Health Care System

[Breast Cancer: Targets and Therapy] This research evaluates costs related to chemotherapy-related adverse events in patients with metastatic breast cancer in an integrated health care delivery system.

Role of Regorafenib as Second-line Therapy and Landscape of Investigational Treatment Options in Advanced Hepatocellular Carcinoma

Role of Regorafenib as Second-line Therapy and Landscape of Investigational Treatment Options in Advanced Hepatocellular Carcinoma

[Journal of Hepatocellular Carcinoma] This review examines the multikinase inhibitors sorafenib and regorafenib, inhibitors of the MET pathway, and immunotherapeutics for the treatment of advanced hepatocellular carcinoma.

Clinical Use of Cabozantinib in the Treatment of Advanced Kidney Cancer: Efficacy, Safety, and Patient Selection

Clinical Use of Cabozantinib in the Treatment of Advanced Kidney Cancer: Efficacy, Safety, and Patient Selection

[OncoTargets and Therapy] This research We reviews the development of cabozantinib in advanced renal cell carcinoma and its role in the treatment landscape.

Monitoring Metastasis and Cachexia in a Patient with Breast Cancer: A Case Study

Monitoring Metastasis and Cachexia in a Patient with Breast Cancer: A Case Study

[Clinical Medicine Insights: Oncology] A case study of a 49-year-old premenopausal woman with metastatic invasive ductal breast carcinoma in the vertebral and iliac bones, which progressed with new metastases to her hips, thigh bones, and vertebrae.

Economic Evaluation of Obinutuzumab in Combination With Chlorambucil in First-line Treatment of Patients With Chronic Lymphocytic Leukemia in Spain

Economic Evaluation of Obinutuzumab in Combination With Chlorambucil in First-line Treatment of Patients With Chronic Lymphocytic Leukemia in Spain

[ClinicoEconomics and Outcomes Research] This research examines the cost-effectiveness of obinutuzumab in combination with chlorambucil (GClb) versus rituximab plus chlorambucil (RClb) in the treatment of previously untreated chronic lymphocytic leukemia.

Ruxolitinib: A Targeted Treatment Option for Patients with Polycythemia Vera

Ruxolitinib: A Targeted Treatment Option for Patients with Polycythemia Vera

[Blood and Lymphatic Cancer: Targets and Therapy] This research provides a summary of the pathobiology of polycythemia vera, and examines challenges associated with traditional PV treatment options and the clinical data for ruxolitinib.

Ezh2 Inhibitors May Offer Cure for Chronic Myelogenous Leukemia

Ezh2 Inhibitors May Offer Cure for Chronic Myelogenous Leukemia

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Inhibition of the protein Ezh2 causes chronic myelogenous leukemia (CML) stem cells to die. Adding drugs that target this protein to imatinib (Gleevec) or other BCR-ABL blockers could result in a cure for this disease.

Cutaneous Basal Cell Carcinoma Arising Within a Keloid Scar: A Case Report

Cutaneous Basal Cell Carcinoma Arising Within a Keloid Scar: A Case Report

[OncoTargets and Therapy] This research presents a rare case of a secondary tumor (BCC) which arose on top of a primary tumor (keloid scar) on the right auricle region in a healthy 23-year-old woman.

Chemotherapy-Induced Dormancy Improves Immunotherapy for Breast Cancer

Chemotherapy-Induced Dormancy Improves Immunotherapy for Breast Cancer

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Inducing quiescent dormancy with conventional chemotherapy makes cancer cells more susceptible to immunotherapy, thereby minimizing potential for tumor recurrence.

Outcomes in Patients With Brain Metastasis from Esophageal Carcinoma

Outcomes in Patients With Brain Metastasis from Esophageal Carcinoma

[Journal of Gastrointestinal Oncology] This research examines factors associated with survival in patients with brain metastasis from esophageal cancer.

Technique Provides Accurate Radiation Dosimetry in Cancer

Technique Provides Accurate Radiation Dosimetry in Cancer

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Novel technique uses injected microbubbles for dosimetry in radiation therapy in patients with cancer.

Experimental Drug Improves Immunotherapy Activity in Triple-Negative Breast Cancer

Experimental Drug Improves Immunotherapy Activity in Triple-Negative Breast Cancer

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An experimental drug, AMPI-109, shows promise as an immunotherapy that sensitizes triple-negative breast cancer cells, enhancing the effectiveness of the drug.

Vitamin C Enhances Epigenetic Treatments in Acute Myeloid Leukemia and Myeloid Dysplastic Syndrome

Vitamin C Enhances Epigenetic Treatments in Acute Myeloid Leukemia and Myeloid Dysplastic Syndrome

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Research using cancer cell lines demonstrated that supplementing standard epigenetic therapy with vitamin C enhanced the drug's antineoplastic action.

A Systematic Review and Meta-analysis of Harmonic Technology Compared With Conventional Techniques in Mastectomy and Breast-conserving Surgery With Lymphadenectomy for Breast Cancer

A Systematic Review and Meta-analysis of Harmonic Technology Compared With Conventional Techniques in Mastectomy and Breast-conserving Surgery With Lymphadenectomy for Breast Cancer

[Breast Cancer: Targets and Therapy] This research compares Harmonic technology and conventional techniques for a range of clinical outcomes and complications in both mastectomy and BCS patients, including axillary lymph node dissection.

Genomic Sequencing Data May Widen Racial and Ethnic Health Disparities

Genomic Sequencing Data May Widen Racial and Ethnic Health Disparities

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Precision medicine based on genetic makeup of tumors is leading to anticancer treatments that target specific patients; however, racial and ethnic minorities are underrepresented in genomic samples, resulting in less benefit from advances in cancer care for these patients.

Recently Discovered microRNA Controls Response to Oxaliplatin in Colorectal Cancer

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Danish researchers identified a microRNA shown to predict whether a patient with colorectal cancer would be resistant to oxaliplatin treatment, a discovery that holds promise of improving both current treatment options and development of future treatment strategies.

Favorable Perioperative Outcomes After Resection of Borderline Resectable Pancreatic Cancer Treated With Neoadjuvant Stereotactic Radiation and Chemotherapy Compared with Upfront Pancreatectomy for Resectable Cancer

Favorable Perioperative Outcomes After Resection of Borderline Resectable Pancreatic Cancer Treated With Neoadjuvant Stereotactic Radiation and Chemotherapy Compared with Upfront Pancreatectomy for Resectable Cancer

[Journal of Gastrointestinal Oncology] This research examines outcomes related to the use of neoadjuvant multi-agent chemotherapy and stereotactic body radiation therapy (SBRT) in borderline resectable pancreatic cancer (BRPC) or locally advanced pancreatic cancer (LAPC) patients.

Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma

Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma

[OncoTargets and Therapy] This research reviews the effects of single-port access transaxillary totally endoscopic thyroidectomy on outcomes following surgery, including quality of life and cosmetic result, in patients with papillary thyroid carcinoma (PTC).

Managing Treatment-related Peripheral Neuropathy in Patients with Multiple Myeloma

Managing Treatment-related Peripheral Neuropathy in Patients with Multiple Myeloma

[Blood and Lymphatic Cancer: Targets and Therapy] This research reviews clinical symptoms, diagnosis, and risk factors of peripheral neuropathy, particularly dealing with the incidence, mechanisms, and management of TiPN and BiPN.

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