Research

Vaginal Cuff Brachytherapy in Endometrial Cancer - A Technically Easy Treatment?

Vaginal Cuff Brachytherapy in Endometrial Cancer - A Technically Easy Treatment?

[Cancer Management and Research] This research examines vaginal cuff brachytherapy (VCB) in the postoperative treatment of high- to intermediate-risk endometrial cancer.

Oncological Safety and Cosmetic Outcomes in Oncoplastic Breast Conservation Surgery, a Review of the Best Level of Evidence Literature

Oncological Safety and Cosmetic Outcomes in Oncoplastic Breast Conservation Surgery, a Review of the Best Level of Evidence Literature

[Breast Cancer: Targets and Therapy] This review examines oncological safety in oncoplastic breast conservation surgery, local recurrence and patient outcome, postoperative complications, and cosmetic outcomes.

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

Chronic obstructive pulmonary disease in patients with lung cancer: prevalence, impact and management challenges

[Lung Cancer: Targets and Therapy] Chronic obstructive pulmonary disease and lung cancer share a common etiological factor and usually coexist in everyday clinical practice.

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

Psychosocial Challenges for Patients With Advanced Lung Cancer: Interventions to Improve Well-being

[Lung Cancer: Targets and Therapy] This research reviews the current literature on psychosocial interventions in lung cancer, and discusses .

Cabazitaxel in Prostate Cancer: Reduced Dose Noninferior to Standard Dose

Cabazitaxel in Prostate Cancer: Reduced Dose Noninferior to Standard Dose

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A smaller dose of cabazitaxel (C20) is noninferior to a larger dose (C25) in the post-docetaxel treatment of mCRPC.

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

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A study on a cohort of women enrolled in the WHI-OS shows that those with a history of periodontal disease had a higher risk for developing some cancers.

A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory

A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory

[Breast Cancer: Targets and Therapy] This research examines literature regarding the prevalence of PTSD in breast cancer patients and reviews mechanisms by which stress impacts cancer risk.

Chemotherapy-associated Paronychia Treated With 2% Povidone-iodine: A Series of Cases

Chemotherapy-associated Paronychia Treated With 2% Povidone-iodine: A Series of Cases

[Cancer Management and Research] This research examines cases of chemotherapy-induced nail changes in individuals treated with taxanes and EGFR inhibitors.

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

This research aims to assess the correlation between quality of life (QoL) and severity of dermatological toxicity in patients with metastatic colorectal cancer.

Relationship Between Breast Cancer and Posttraumatic Stress Disorder Inconclusive

Relationship Between Breast Cancer and Posttraumatic Stress Disorder Inconclusive

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Although a strong correlation between breast cancer diagnosis and stress has been noted — particularly in the form of posttraumatic stress disorder (PTSD) — there is no demonstrable evidence to suggest a direct causal relationship between them.

New Evidence Shows Metastases May Spread Independently of Lymph Nodes

New Evidence Shows Metastases May Spread Independently of Lymph Nodes

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A recent study found that nodal tumors and distant metastases originate from different areas of the primary tumor, suggesting that cancer spreads independently of the lymph nodes.

Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study

Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study

[Breast Cancer: Targets and Therapy] The goal of this research was to evaluate the acute changes in PFTs in breast carcinoma patients who received adjuvant chemotherapy and were treated with PMRT including SC regions.

Can Biosimilars Help Achieve the Goals of US Health Care Reform?

Can Biosimilars Help Achieve the Goals of US Health Care Reform?

[Cancer Management and Research] This research examines the pros and cons of the Affordable Care Act enactment and the possible beneficial role biosimilars may play in this environment.

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

[Cancer Management and Research] This research examines preferences and risk tolerance among patients and oncologists in the USA for anticancer drugs to treat metastatic colorectal cancer (mCRC).

Multiscale Modeling Framework Predicts Tumor Growth

Multiscale Modeling Framework Predicts Tumor Growth

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Researchers from 3 Texas institutions collaborated on a multiscale framework for modeling tumor growth, with potential to inform growth patterns and tumor density.

Manipulation Increases Susceptibility of Triple-Negative Breast Cancer to Conventional Therapy

Manipulation Increases Susceptibility of Triple-Negative Breast Cancer to Conventional Therapy

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Researchers manipulated triple-negative breast cancer cells to make them susceptible to conventional antiestrogen therapy for breast cancer.

Thyroid Cancer Incidence Increasing Among Younger, Hispanic, African American Populations

Thyroid Cancer Incidence Increasing Among Younger, Hispanic, African American Populations

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A report on incidence of thyroid cancer shows incidence of the disease is increasing among certain populations: younger persons, Hispanic, and African American.

JAK1, JAK2 Inhibition Improves Outcomes in Myeloproliferative Neoplasms, But More Is Needed

JAK1, JAK2 Inhibition Improves Outcomes in Myeloproliferative Neoplasms, But More Is Needed

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Myelofibrosis, extensive splenomegaly, and symptomatic burden are significantly improved for patients with MPN by JAK1 and JAK2 inhibition; however, some major needs in this patient group are still largely unmet.

Analysis & Perspective on Practical and Ethical Use and Interpretation of Whole Genome Sequencing Data During Clinical Trials

Analysis & Perspective on Practical and Ethical Use and Interpretation of Whole Genome Sequencing Data During Clinical Trials

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Despite the value of genomic sequence information, nurses need to be aware of the limitations of this information and ethical concerns regarding sharing it with patients.

Mastectomy Skin Flap Necrosis: Challenges and Solutions

Mastectomy Skin Flap Necrosis: Challenges and Solutions

[Breast Cancer: Targets and Therapy] This research discusses the management options for incidents of mastectomy skin flap necrosis (MSFN).

Research Shows iPS-ML/IFN-β Migrates to, Penetrate Liver Cancer Tumors

Research Shows iPS-ML/IFN-β Migrates to, Penetrate Liver Cancer Tumors

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Decreased liver tumor growth and improved survival in a mouse model were noted after injecting iPS-ML/IFN-β.

A Single Institution Report of 19 Hepatocellular Carcinoma Patients With Bile Duct Tumor Thrombus

A Single Institution Report of 19 Hepatocellular Carcinoma Patients With Bile Duct Tumor Thrombus

[Journal of Hepatocellular Carcinoma] This research examines the outcomes of HCC patients with BDTT in a single institution.

Barriers in Routine Care Coverage for Cancer Clinical Trial Participants Still Exist

Barriers in Routine Care Coverage for Cancer Clinical Trial Participants Still Exist

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Despite the ACA mandate on coverage for clinical trial participants, many facilities involved in cancer research still coping with insurance denials for participants.

Serum Liver Enzymes Serve as Prognostic Factors in Patients With Intrahepatic Cholangiocarcinoma

Serum Liver Enzymes Serve as Prognostic Factors in Patients With Intrahepatic Cholangiocarcinoma

This study examines the influences of liver enzymes on the overall survival in a number of patients with intrahepatic cholangiocarcinoma (ICC).

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

[OncoTargets and Therapy] This research examines the lymphatic flow in the arm following breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphoscintigraphy (LS).

NCI Funds Project to Investigate Cancer Progression, Survival in African Americans

NCI Funds Project to Investigate Cancer Progression, Survival in African Americans

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NCI awarded a $9 million grant to Barbara A. Karmanos Cancer Institute and Wayne State University to explore factors contributing to racial disparities in cancer.

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

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Leflunomide, an immunosuppressor FDA-approved for rheumatoid arthritis, is effective against breast cancer in mouse study.

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

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Nicotinamide riboside, a type of B3 vitamin, was shown to prevent chemotherapy-induced peripheral neuropathy in an animal-model study.

Docetaxel-associated Myalgia-arthralgia Syndrome in Patients With Breast Cancer

Docetaxel-associated Myalgia-arthralgia Syndrome in Patients With Breast Cancer

[Breast Cancer: Targets and Therapy] This research examines possible risk factors and effectiveness of treatments for docetaxel-associated myalgia-arthralgia syndrome.

Pediatric Hepatocellular Carcinoma: Challenges and Solutions

Pediatric Hepatocellular Carcinoma: Challenges and Solutions

[Journal of Hepatocellular Carcinoma] This research examines the medical challenges presented by pediatric hepatocellular carcinoma (HCC).

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