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REPRONEX 75 IU
Infertility
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Drug Name:

REPRONEX 75 IU Rx

Generic Name and Formulations:
Follicle-stimulating hormone 75 IU + luteinizing hormone 75 IU; per vial; pwd for SC or IM inj after reconstitution.

Company:
Ferring Pharmaceuticals, Inc.

Therapeutic Use:

Indications for REPRONEX 75 IU:

Multiple follicular development for in vitro fertilization and ovulation induction in women who have previously received pituitary suppression.

Adult:

For controlled ovarian hyperstimulation: 150 IU daily for 1st 5 days of treatment, followed by 5000–10000 Units of hCG 1 day after last dose. ART: Initially 225 IU followed by 5000–10000 Units of hCG. For both: Adjust in increments of 75–150 IU at intervals of at least 2 days; max 450 IU/day and 12 days treatment.

Children:

Not applicable.

Contraindications:

Primary ovarian failure. Uncontrolled thyroid or adrenal dysfunction. Intracranial lesions. Undiagnosed abnormal vaginal bleeding. Ovarian cysts or enlargement. Pregnancy (Cat.X).

Warnings/Precautions:

Be fully familiar with infertility treatment and its complications before using this product. Do complete gynecological and endocrinological exam first. Monitor appropriate lab values. May cause false (+) pregnancy test. Thromboembolic disorders. If ovaries are excessively enlarged on last day of therapy do not administer hCG; this decreases risk of ovarian hyperstimulation syndrome (OHSS). Discontinue if OHSS occurs. Nursing mothers.

Adverse Reactions:

OHSS with pulmonary and vascular complications, hemoperitoneum, adnexal torsion, ovarian enlargement or cysts, abdominal pain, flu-like symptoms, GI disturbances, local reactions, rash, dizziness, tachycardia, dyspnea, tachypnea, risk of high order multiple births.

How Supplied:

Vials—1, 5

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