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RECOTHROM
Bleeding disorders
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Drug Name:

RECOTHROM Rx

Generic Name and Formulations:
Thrombin [recombinant] 5000 IU, 20000 IU; per vial; pwd for topical use after reconstitution; preservative-free.

Company:
ZymoGenetics, Inc.

Therapeutic Use:

Indications for RECOTHROM:

Aid to hemostasis for minor bleeding/oozing from capillaries and venules when standard surgical techniques are inadequate or ineffective. May use with absorbable gelatin sponge.

Adult:

Apply directly to bleeding area, or soak into absorbable gelatin sponge and apply in a single layer.

Children:

Not recommended.

Contraindications:

Not for direct injection into circulatory system. Not for treatment of massive or brisk arterial bleeding. Hypersensitivity to hamster proteins.

Warnings/Precautions:

Avoid systemic absorption (thrombosis may occur). Hypersensitivity to snake proteins. Pregnancy (Cat.C).

Pharmacological Class:

Topical hemostatic.

Adverse Reactions:

Incision site complication, infection, pain, bleeding, nausea/vomiting, cardiac events, thromboembolic events.

How Supplied:

Single-use vial (5000 IU, 20000 IU)—1 (w. diluent, supplies)
20000 IU Recothrom kit (co-packaged with ZymoGenetics Spray Applicator Kit)—1

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