Radiotherapy

Pilot Study Assesses Feasibility of Nurse-led Sexual Rehabilitation Program

Pilot Study Assesses Feasibility of Nurse-led Sexual Rehabilitation Program

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Researchers report on the feasibility of a nurse-led sexual rehabilitation intervention to target sexual recovery and vaginal dilation in women who underwent pelvic radiation therapy and brachytherapy for gynecologic cancers.

Study Supports Routine Use of IMRT for Locally Advanced NSCLC

Study Supports Routine Use of IMRT for Locally Advanced NSCLC

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IMRT was associated with lower rates of severe pneumonitis and cardiac doses compared with 3D-CRT in patients with locally advanced NSCLC.

Patients Receiving RT in APBI Facilities Despite Eligibility for Observation

Patients Receiving RT in APBI Facilities Despite Eligibility for Observation

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Patients with early stage breast cancer who received breast-conserving surgery and were eligible for observation were more likely to undergo adjuvant radiotherapy in facilities performing APBI.

ASCO, ASTRO Issue Guideline Update for Postmastectomy RT

ASCO, ASTRO Issue Guideline Update for Postmastectomy RT

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The American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology have issued a joint consensus guideline update for the use of radiotherapy following mastectomy in patients with breast cancer.

WBRT Adds Little Benefit for NSCLC With Brain Metastases

WBRT Adds Little Benefit for NSCLC With Brain Metastases

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Adding WBRT to dexamethasone and best supportive care provides little additional benefit for patients with NSCLC and brain metastases who are ineligible to undergo resection or stereotactic radiotherapy.

Study Evaluates Systemic Therapy Use With RT Among Older Patients With Head and Neck Cancer

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In contrast of available prospective data, most older patients with locoregionally advanced head and neck cancer are treated with definitive radiotherapy also receive systemic therapy.

Postop RT Deferral Associated With Worse Survival in Children With Medulloblastoma

Postop RT Deferral Associated With Worse Survival in Children With Medulloblastoma

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Despite the use of adjuvant chemotherapy, deferral of postoperative radiotherapy is associated with worse survival in pediatric patients with medulloblastoma.

Functional Status Linked to Treatment Choice for Prostate Cancer

Functional Status Linked to Treatment Choice for Prostate Cancer

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Functional status, a person's ability to perform normal activities of daily living, is associated with treatment choice for patients with prostate cancer.

Adding Temozolomide to Radiotherapy Improves Survival in Elderly Patients With Newly Diagnosed Glioblastoma

Adding Temozolomide to Radiotherapy Improves Survival in Elderly Patients With Newly Diagnosed Glioblastoma

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The addition of temozolomide to standard short-course radiation therapy significantly improved both overall and progression-free survival in elderly patients with newly diagnosed glioblastoma, results from the first study to test this combination in this age group concluded in a plenary presentation at the ASCO 2016 Annual Meeting.

Nimotuzumab + Radiotherapy Less Toxic Than Cisplatin + Radiotherapy for Stage III/IVB Nasopharyngeal Cancer

Nimotuzumab + Radiotherapy Less Toxic Than Cisplatin + Radiotherapy for Stage III/IVB Nasopharyngeal Cancer

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Patients with locally advanced nasopharyngeal cancer concurrently treated with nimotuzumab and radiotherapy had similar rates of progression-free and overall survival to those treated with cisplatin and radiotherapy, but with significantly fewer GI and hematologic toxicities, according to phase 3 trial results presented at the ASCO 2016 Annual Meeting.

Cisplatin, Cetuximab Show Similar Locoregional Control in Unresectable Head and Neck Cancer

Cisplatin, Cetuximab Show Similar Locoregional Control in Unresectable Head and Neck Cancer

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Survival results from the first randomized phase 3 trial to compare cisplatin-radiotherapy with cetuximab-radiotherapy after induction chemotherapy in patients with locally advanced unresectable head and neck cancer remain inconclusive, with both arms showing good locoregional control, greater than 50% at 3 years, attendees at the ASCO 2016 Annual Meeting were told.

Vessel-Sparing Radiation Successfully Treats Prostate Cancer, Maintains Quality of Life

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Radiation therapy delivered to the critical vessels surrounding the prostate can result in erectile dysfunction and bladder and renal irritation. Vessel-sparing radiation and an improved understanding of the anatomy of the prostate can reduce these effects.

Training Patients With Breast Cancer to Achieve Prolonged Breath Holds Could Improve Targeted Radiotherapy

Training Patients With Breast Cancer to Achieve Prolonged Breath Holds Could Improve Targeted Radiotherapy

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Patients with breast cancer can be trained to achieve a breath hold lasting more than 5 minutes, allowing for targeted administration of radiotherapy with a single dose per daily session that can minimize damage to surrounding tissues.

Radiotherapy Plus Hormone Therapy Improves Long-term Survival for Patients With Prostate Cancer

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Radiotherapy in combination with anti-androgen hormone therapy halves the risk of death from prostate cancer 15 years after diagnosis compared with hormone therapy alone.

Age Affects Outcomes After Mastectomy or Breast-conserving Therapy for Early Stage Breast Cancer

Age Affects Outcomes After Mastectomy or Breast-conserving Therapy for Early Stage Breast Cancer

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For women younger than 45 years with early stage breast cancer that has not spread to the lymph nodes, opting for breast-conserving therapy with RT was associated with higher risk of local recurrence over 20 years compared with mastectomy and no RT.

Shortened Radiation Therapy Schedule No Worse Than Conventional Radiotherapy in Low-Risk Prostate Cancer

Shortened Radiation Therapy Schedule No Worse Than Conventional Radiotherapy in Low-Risk Prostate Cancer

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Treatment with a hypofractionated radiotherapy (HRT) schedule achieved similar efficacy as treatment with the longer, conventional RT (CRT) schedule in men with low-risk prostate cancer.

Adaptive IGRT for Urinary Bladder Cancer Is Clinically Feasible With Good Outcomes

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A bladder preservation rate of 83% occurred at 3 years after a trimodality treatment approach for localized bladder cancer that used adaptive image-guided, intensity-modulated radiation therapy (IG-IMRT).

Managing Radiotherapy-Induced Breakthrough Cancer Pain

Managing Radiotherapy-Induced Breakthrough Cancer Pain

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Nasal spray effectively relieves intense breakthrough pain associated with radiotherapy planning and treatment.

Partial Breast Radiotherapy May Be Effective for Some Women With Early Breast Cancer

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Partial breast radiotherapy was noninferior to whole breast radiotherapy in regard to local recurrence in women with low-risk early breast cancer.

Surgery Improves Survival After Radiotherapy Failure in Men With Prostate Cancer

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A complex surgical procedure to remove the prostate achieves excellent long-term survival for men with prostate cancer after radiation therapy has failed.

Risk for Some Secondary Cancers After Radiotherapy For Prostate Cancer is Increased

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Although reported absolute rates of second malignancies after radiotherapy for prostate cancer are very low, it is associated with higher rates of bladder, colon, and rectal cancers in patients who undergo radiotherapy for prostate cancer.

Radiotherapy/Histone Deacetylase Inhibitor Combination Safe, Effective in High-grade Gliomas

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Adding panobinostat to radiotherapy appears safe, tolerable, and has preliminary efficacy for treating recurrent high-grade gliomas.

Targeted Radiation Holds Promise for Early Breast Cancer

Targeted Radiation Holds Promise for Early Breast Cancer

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Limited radiotherapy effective after low-risk tumors are removed, but questions remain.

Sleep Disturbance Is a Common Challenge for Patients With Cancer

Sleep Disturbance Is a Common Challenge for Patients With Cancer

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Sleep disturbances in patients with cancer preceded radiotherapy treatment and are associated with previous treatment, disease progression, and psychological symptoms.

ASTRO Develops a Template to Facilitate Radiotherapy-Specific Cancer Survivorship Care Plans

ASTRO Develops a Template to Facilitate Radiotherapy-Specific Cancer Survivorship Care Plans

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As the American College of Surgeons' Commision on Cancer milestones approach, ASTRO publishes a template to ensure consistent, comprehensive survivorship care plans can be developed for cancer survivors whose treatment involved radiotherapy.

Imaging, Physical Examination Find Most Recurrences of HPV-positive Oropharyngeal Cancer

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Posttreatment imaging at 3 months and physical examinations during the 6 months following treatment can detect most recurrences in patients treated with definitive radiation therapy for HPV-associated oropharyngeal cancer.

Adding SIRT to mFOLFOX6 ± Bevacizumab in mCRC Delays Progression in Liver

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Adding selective internal radiation therapy to FOLFOX-based first-line chemotherapy in patients with mCRC and liver metastases significantly delayed disease progression in the liver.

Tailoring Decisions on Radiation Therapy for DCIS

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Decisions about radiotherapy after breast-conserving surgery for ductal carcinoma in situ can be tailored on the basis of patient factors, tumor biology, and the prognostic score, according to research.

Mortality Rates in Patients With Esophageal Cancer Are Lower With The Use of Intensity-modulated Radiotherapy

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Intensity-modulated radiotherapy (IMRT) is significantly associated with lower all-cause, cardiac, and other-cause mortality rates in patients with esophageal cancer.

Type of Electromagnetic Field Therapy Improves Survival for Patients With Brain Tumor

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Progression-free and overall survival were prolonged with electromagnetic field and chemotherapy maintenance therapy in patients with a brain tumor.

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