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RABAVERT
Vaccines
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Drug Name:

RABAVERT Rx

Generic Name and Formulations:
Rabies vaccine, inactivated 2.5IU/mL; pwd for IM inj after reconstitution; may contain trace amounts of bovine gelatin, chicken protein, neomycin, chlortetracycline, and amphotericin B.

Company:
Novartis Pharmaceuticals Corp

Therapeutic Use:

Indications for RABAVERT:

Preexposure immunization and post-exposure prophylaxis of rabies.

Adults and Children:

Adults: inject into deltoid area. Small children: inject into thigh. Preexposure immunization: 3 inj of 1mL IM each on day 0, 7, and either day 21 or 28. Booster: 1 dose as needed to maintain antibody titer (see literature). Post-exposure prophylaxis: a 5-dose regimen of 1mL IM given on days 0, 3, 7, 14, and 28 (give 1st dose with human rabies immunoglobulin at a separate site). If previously immunized: 2 inj of 1mL each on days 0 and 3 (no immune globulin needed).

Warnings/Precautions:

Immunocompromised: may get suboptimal response (monitor titers). Postpone preexposure immunization during acute febrile illness or infection. Egg allergy. Have epinephrine inj (1:1000) available. Pregnancy (Cat.C).

Interactions:

Immunosuppressants: may get suboptimal response.

Adverse Reactions:

Local reactions, lymphadenopathy, headache, myalgia, malaise, dizziness, neuroparalytic events, anaphylaxis.

How Supplied:

Single-dose vial—1 (w. diluent)

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