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PULMOZYME
Lung surfactants/mucolytics
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Drug Name:

PULMOZYME Rx

Generic Name and Formulations:
Dornase alfa (recombinant human DNase) 1mg/mL; soln for inh; preservative-free.

Company:
Genentech, Inc.

Therapeutic Use:

Indications for PULMOZYME:

Management of cystic fibrosis in conjunction with standard therapies to improve pulmonary function.

Adults and Children:

<3months: not recommended. Use appropriate nebulizer. Do not dilute. >5yrs: 2.5mg once daily via nebulization; may increase to 2.5mg twice daily (see literature).

Warnings/Precautions:

For patients <5yrs of age, use only if there is a potential for benefit in pulmonary function or in risk of respiratory tract infection. Use only with recommended nebulizers. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Do not mix with other drugs in nebulizer.

Adverse Reactions:

Pharyngitis, voice alteration, laryngitis, rash, chest pain, conjunctivitis.

How Supplied:

Amps (2.5mL)—30

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