Prostate Cancer

Fluciclovine PET/CT Improves Targeted Radiation Treatment of Recurrent Prostate Cancer

Fluciclovine PET/CT Improves Targeted Radiation Treatment of Recurrent Prostate Cancer

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F-18-fluciclovine PET helps detect and localize recurrent prostate cancer allowing for individualized, targeted therapy.

Single Fraction of HDR Brachytherapy Found Effective in Localized Prostate Cancer

Single Fraction of HDR Brachytherapy Found Effective in Localized Prostate Cancer

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A single 19-Gy fraction of brachytherapy was found as effective as a longer regimen of low-dose-rate brachytherapy in localized prostate cancer.

Cabozantinib Activates Innate Immune Response, Eliminating Prostate Cancer

Cabozantinib Activates Innate Immune Response, Eliminating Prostate Cancer

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Cabozantinib activated innate immunity and completely eradicated prostate cancer in a study using a mouse model.

Moderate Hypofractionation Effective, Cost-Efficient, and Tolerable in Prostate Cancer

Moderate Hypofractionation Effective, Cost-Efficient, and Tolerable in Prostate Cancer

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Shorter course of higher dose radiation therapy provide effective treatment, costs less, and is easier on patients than current standard radiation therapy course.

No Association Between Vasectomy and Prostate Cancer Risk

No Association Between Vasectomy and Prostate Cancer Risk

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There is no association between vasectomy and the risk of overall, high-grade, or advanced-stage prostate cancer or prostate cancer-related mortality.

Low-Fat Meal May Allow for Lower Doses of Abiraterone Acetate in Prostate Cancer Patients

Low-Fat Meal May Allow for Lower Doses of Abiraterone Acetate in Prostate Cancer Patients

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A lower dose of abiraterone acetate with a low fat meal may have the same effect as taking the standard dose as recommended on an empty stomach.

Patients Undergoing Multiple Systemic Therapies for Metastatic Prostate Cancer Expect a Cure

Patients Undergoing Multiple Systemic Therapies for Metastatic Prostate Cancer Expect a Cure

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Treatment expectations of individuals with metastatic prostate cancer and their health care providers often do not match.

Overall Health Worse in African American Men Undergoing Active Surveillance For Prostate Cancer

Overall Health Worse in African American Men Undergoing Active Surveillance For Prostate Cancer

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African American men choosing active surveillance for their low-grade prostate cancer have overall poorer health than non-African American men undergoing active surveillance.

Follow-up Rates in Active Surveillance for Prostate Cancer Higher in University-Based vs Safety-Net Hospitals

Follow-up Rates in Active Surveillance for Prostate Cancer Higher in University-Based vs Safety-Net Hospitals

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A significant difference exists in the failure to follow-up rates among patients undergoing active surveillance at university-based hospitals versus safety-net hospitals.

Decipher Genomic Classifier Prognostic for Distant Prostate Metastasis

Decipher Genomic Classifier Prognostic for Distant Prostate Metastasis

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The Decipher genomic classifier obtained from biopsy samples was prognostic for distant metastases and prostate cancer-specific mortality.

GUCS 2017: Adjuvant Trials in Post-radical Prostatectomy Prostate Cancer Feasible

GUCS 2017: Adjuvant Trials in Post-radical Prostatectomy Prostate Cancer Feasible

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A phase 3 study presented at the 2017 Genitourinary Cancers Symposium demonstrated the feasibility of conducting adjuvant trials.

Immunotherapy and the Future of Prostate Cancer Treatment

Immunotherapy and the Future of Prostate Cancer Treatment

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Despite early failures, there may be a role for single-agent and combination immunotherapy for patients with prostate cancer.

Targeting AR Mutations Promising in Metastatic Prostate Cancer

Targeting AR Mutations Promising in Metastatic Prostate Cancer

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A higher overall number of genetic alterations in cell-free circulating tumor DNA (ctDNA) were associated with worse treatment outcomes.

Adding Bicalutamide to Salvage RT Improves OS in Recurrent Prostate Cancer

Adding Bicalutamide to Salvage RT Improves OS in Recurrent Prostate Cancer

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Investigators studied the effects of adding antiandrogen therapy to radiotherapy on cancer control and overall survival in men with prostate cancer recurrence after radical prostatectomy.

Clinicians May Want To Address Emotional Stress to Prevent Overtreatment of Localized Prostate Cancer

Clinicians May Want To Address Emotional Stress to Prevent Overtreatment of Localized Prostate Cancer

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Some men with low-risk prostate cancer may opt for more aggressive treatments due to emotional distress.

Prostate Cancer Treatment Rates Decrease Following Changes in Treatment Recommendations

Prostate Cancer Treatment Rates Decrease Following Changes in Treatment Recommendations

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The implementation of recommendations opposing regular prostate cancer screening appear to have lowered treatment rates dramatically.

Longer Dosing Interval of Zoledronic Acid May Be Acceptable for Bone Metastases

Longer Dosing Interval of Zoledronic Acid May Be Acceptable for Bone Metastases

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Results from a phase 3 trial comparing a 12-week dosing interval with the standard 4-week dosing interval of zoledronic acid to reduce the incidence of skeletal-related events and pain in patients with bone metastases.

Hormone Therapy for Prostate Cancer (Fact Sheet)

Hormone Therapy for Prostate Cancer (Fact Sheet)

This fact reviews how hormone therapy may be used to treat prostate cancer, treatment options for castration-resistant prostate cancer, and side effects of hormone therapy.

Less Intense Surveillance Acceptable for Some Prostate Cancer Cases

Less Intense Surveillance Acceptable for Some Prostate Cancer Cases

Patients on active surveillance with stable disease may be candidates for less intense surveillance

Most Common Reason for Prostate Cancer Second Opinions: More Information

Most Common Reason for Prostate Cancer Second Opinions: More Information

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Although many men obtain a second opinion regarding their prostate cancer care options, they seldom deviate from the original course of action.

MRI Plays a Role After Negative Prostate Biopsy

MRI Plays a Role After Negative Prostate Biopsy

Magnetic resonance imaging and MRI-targeted biopsy can facilitate detection of clinically significant prostate disease.

Cognitive Therapy Not More Effective Than Usual Care for Distress Reduction in Advanced PCa

Cognitive Therapy Not More Effective Than Usual Care for Distress Reduction in Advanced PCa

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Advanced prostate cancer is associated with substantial psychosocial morbidity; therefore, this study was conducted to evaluate whether mindfulness-based cognitive therapy reduces distress in this population.

Guidelines Issued for Prostate MRI After Negative Biopsy

Guidelines Issued for Prostate MRI After Negative Biopsy

Consensus statement presents guidelines for prostate magnetic resonance imaging (MRI) in patients with negative biopsy.

Role of Chemotherapy and Mechanisms of Resistance to Chemotherapy in Metastatic Castration-Resistant Prostate Cancer

Role of Chemotherapy and Mechanisms of Resistance to Chemotherapy in Metastatic Castration-Resistant Prostate Cancer

[Clinical Medicine Insights: Oncology] This research examines the various mechanisms of resistance to chemotherapy in metastatic CRPC and the potential role of emerging regimens and agents in varying clinical phases of development.

Cancer Patients Benefit From Exercise Both During and After Treatment

Cancer Patients Benefit From Exercise Both During and After Treatment

Studies show better physical function and quality of life for cancer patients who do strength training or aerobic activity.

Second Opinions Rarely Change Prostate Cancer Decisions

Second Opinions Rarely Change Prostate Cancer Decisions

The impact of additional opinions on patient decision-making is limited.

Study Shows Effects of 2012 USPSTF Recommendation Against PSA Screening

Study Shows Effects of 2012 USPSTF Recommendation Against PSA Screening

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Researchers report on their evaluation of the impact of the 2012 USPSTF recommendation on volumes of prostate biopsy and radical prostatectomy.

Study Suggests More Men With Prostate Cancer Would Choose Active Surveillance if it Were Offered

Study Suggests More Men With Prostate Cancer Would Choose Active Surveillance if it Were Offered

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Researchers analyzed data from the NPCR of Sweden to determine whether more US men with prostate cancer would choose active surveillance if it were presented as a treatment option.

Androgen Deprivation Therapy for Prostate Cancer May Increase Dementia Risk

Androgen Deprivation Therapy for Prostate Cancer May Increase Dementia Risk

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Growing evidence suggests a link between androgen deprivation therapy (ADT) and cognitive dysfunction, but whether it may contribute to the risk of dementia more broadly is unclear. In this study, researchers examined the association of ADT with subsequent development of dementia in patients with prostate cancer.

Early Post-op RT Linked to Worse Functional Outcomes in Prostate Cancer

Early Post-op RT Linked to Worse Functional Outcomes in Prostate Cancer

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Radiotherapy administered postoperatively within 1 year of radical prostatectomy was associated with worse functional outcomes compared with radiotherapy administered 1 year or more after surgery.

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