Prostate Cancer

Taxane Acute Pain Syndrome in Cancer Therapy: Occurrence, Impact on Quality of Life

Taxane Acute Pain Syndrome in Cancer Therapy: Occurrence, Impact on Quality of Life

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Results of a prospective study of patients with breast or prostate cancer demonstrate the impact of taxane-based chemotherapy on quality of life.

Increased Monitoring Increases Cost, Not Quality of Care or Survival, in Prostate Cancer

Increased Monitoring Increases Cost, Not Quality of Care or Survival, in Prostate Cancer

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In an evaluation of SEER-Medicare data, researchers sought to determine the benefits of extreme use of monitoring in patients with metastatic prostate cancer at the end of life on survival outcomes, quality of life, and costs.

Androgen-Deprivation Therapy for Prostate Cancer May Cause Nocturia, Sleep Disturbance

Androgen-Deprivation Therapy for Prostate Cancer May Cause Nocturia, Sleep Disturbance

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ADT recipients reported worse subjective sleep disturbance, researchers found.

Oral Androgen Receptor Inhibitor Granted FDA Approval for Nonmetastatic CRPC

Oral Androgen Receptor Inhibitor Granted FDA Approval for Nonmetastatic CRPC

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According to the FDA, the drug approval is the first to use the end point of metastasis-free survival.

Aggressive Therapy Provides No Additional Advantage in Metastatic Prostate Cancer

Aggressive Therapy Provides No Additional Advantage in Metastatic Prostate Cancer

Aggressive therapy does not appear to be more beneficial than conservative androgen deprivation therapy alone, according to a study.

Single Screening for PSA Levels Does Not Improve Survival in Prostate Cancer

Single Screening for PSA Levels Does Not Improve Survival in Prostate Cancer

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Researchers sought to determine the effect single PSA testing had on prostate cancer diagnosis, mortality, and all-cause mortality.

Cost vs Benefits: The Controversy Over Proton Beam Radiotherapy

Cost vs Benefits: The Controversy Over Proton Beam Radiotherapy

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At $225 million per system, the precision of proton beam radiotherapy is not necessarily overshadowing its high costs. Yet ongoing studies seek to determine how this technology fits into current treatment regimens for prostate, breast, and other cancers.

Travel Distance to Prostate Cancer Treatment Influences Treatment Choice 

Travel Distance to Prostate Cancer Treatment Influences Treatment Choice 

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Long-distance travel was more strongly associated with definitive prostate SBRT use, researchers found.

Apalutamide Prolongs Time to Metastasis in Castration-resistant Prostate Cancer

Apalutamide Prolongs Time to Metastasis in Castration-resistant Prostate Cancer

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SPARTAN phase 3 study shows that apalutamide prolongs metastasis-free survival and time to symptomatic progression compared with placebo among men with nonmetastatic CRPC.

Susceptibility Gene Mutations Common in Those With Pancreatic Cancer and History of Other Cancers

Susceptibility Gene Mutations Common in Those With Pancreatic Cancer and History of Other Cancers

Those with pancreatic adenocarcinoma and a personal history of another cancer associated with hereditary breast and ovarian cancer or Lynch syndrome may be more likely to carry germline mutations.

Daily IGRT Regimen for Prostate Cancer Improves Rectal Toxicity, Not OS

Daily IGRT Regimen for Prostate Cancer Improves Rectal Toxicity, Not OS

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Researchers present findings of a comparison of daily image-guided radiotherapy (IGRT) vs a weekly regimen in patients with N0 localized prostate cancer at the 2018 GU Cancers Symposium.

Active Surveillance, Repeat Biopsies Not Linked to Post Prostatectomy Complications

Active Surveillance, Repeat Biopsies Not Linked to Post Prostatectomy Complications

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Rates of erectile dysfunction and urinary incontinence at 1, 2, and 3 years after radical surgery are not higher among men who have multiple prostate biopsies while on active surveillance for prostate cancer.

Adjuvant Radiotherapy Found Superior to Early-Salvage RT in Prostate Cancer

Adjuvant Radiotherapy Found Superior to Early-Salvage RT in Prostate Cancer

Propensity score-matched study compared adjuvant radiotherapy with surveillance and early-salvage radiotherapy after prostatectomy in men with prostate cancer.

Priority Review of New Drug Application Granted to Apalutamide for CRPC

Priority Review of New Drug Application Granted to Apalutamide for CRPC

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Data from the phase 3 SPARTAN trial prompted the FDA's Priority Review designation for apalutamide.

Active Surveillance Required Following Prostate Cancer Focal Ablation

Active Surveillance Required Following Prostate Cancer Focal Ablation

In a small but meaningful number of patients, Gleason pattern 4 disease missed by MRI and systematic biopsy is present outside the focal ablation zone.

Testosterone Therapy May Lower Prostate Cancer Incidence

Testosterone Therapy May Lower Prostate Cancer Incidence

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Hypogonadal men who received testosterone replacement therapy had a lower incidence of prostate cancer than those who did not, and their cancers were less severe.

Impact of Prostate Cancer Diagnosis, Treatment Choice on Quality of Life

Impact of Prostate Cancer Diagnosis, Treatment Choice on Quality of Life

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The impact of prostate cancer treatment is well documented; however, in this study, researchers sought to determine the effect on health-related quality of life for patients from diagnosis through treatment planning to initiation of treatment.

Compound in Teas, Peas, Soybeans May Increases Prostate Cancer Risk

Compound in Teas, Peas, Soybeans May Increases Prostate Cancer Risk

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An analysis of an intervention arm of the PLCO Cancer Screening Trial evaluated the risk of prostate cancer relative to dietary consumption of isoflavones, a dietary compound found in some plant foods.

Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret

Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret

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A survey followed up with an assessment via validated tools determined that patients with prostate cancer who experienced regret after radical prostatectomy were more susceptible to depression-associated sleep disorders.

Androgen Deprivation Therapy for Prostate Cancer Increases Risk of CVD

Androgen Deprivation Therapy for Prostate Cancer Increases Risk of CVD

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The risk of cardiovascular disease such as heart failure, arrhythmias, and conduction disorders are greater in men with localized prostate cancer who were treated with androgen deprivation therapy.

Osteoporosis Medication Improves Bone Health in ADT-Treated Prostate Cancer

Osteoporosis Medication Improves Bone Health in ADT-Treated Prostate Cancer

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Osteoporosis medications were found to reduce bone mineral density loss and risk of fracture in men with nonmetastatic prostate cancer being treated with androgen-deprivation therapy.

Cabazitaxel in Prostate Cancer: Reduced Dose Noninferior to Standard Dose

Cabazitaxel in Prostate Cancer: Reduced Dose Noninferior to Standard Dose

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A smaller dose of cabazitaxel (C20) is noninferior to a larger dose (C25) in the post-docetaxel treatment of mCRPC.

Cabazitaxel Does Not Prolong Overall Survival vs Docetaxel in Metastatic Prostate Cancer

Cabazitaxel Does Not Prolong Overall Survival vs Docetaxel in Metastatic Prostate Cancer

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Cabazitaxel does not prolong OS in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer compared with the first-line chemotherapy agent docetaxel.

Risk for Prostate Cancer Not Associated With Vasectomy, Meta-analysis Affirms

Risk for Prostate Cancer Not Associated With Vasectomy, Meta-analysis Affirms

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Meta-analysis of data from more than 50 studies reaffirms that vasectomy is not associated with increased risk of prostate cancer.

Obese Men at Higher Risk for Aggressive Prostate Cancer

Obese Men at Higher Risk for Aggressive Prostate Cancer

Study found taller and heavier males were more likely to develop prostate cancer, and they are also more likely to die of the disease.

Long Term Survivors of Prostate Cancer Express Treatment Decision Regret for Up to 15 Years

Long Term Survivors of Prostate Cancer Express Treatment Decision Regret for Up to 15 Years

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Study results show that patients with prostate cancer express treatment decision regret, with concerns regarding sexual function, bowel function, and PSA most commonly associated with regret.

Metabolism of Next-Generation Prostate Cancer Drugs Share Similarities

Metabolism of Next-Generation Prostate Cancer Drugs Share Similarities

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How the body metabolizes next-generation anti-androgen agents affects their anti-tumor activity in the treatment of prostate cancer.

Prostate-specific PET and CT Imaging Improves Detection of Disease and Patient Care

Prostate-specific PET and CT Imaging Improves Detection of Disease and Patient Care

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Prostate-specific molecular imaging, such as PET and CT, can detect more cancer and improve patient care.

Significance of Prostate Cancer Treatment-Related Factors Differ in Black, White Men

Significance of Prostate Cancer Treatment-Related Factors Differ in Black, White Men

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A survey of men with prostate cancer revealed that treatment-related factors impact treatment decisions differently in black men compared with white men.

Prehabilitation May Benefit Older Men Initiating ADT for Prostate Cancer

Prehabilitation May Benefit Older Men Initiating ADT for Prostate Cancer

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Prehabilitation before initiating ADT in older men with prostate cancer may improve functioning, even in men on short-term ADT.

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